Stimulation-induced status epilepticus: role of the hippocampal mossy fibers in the seizures and associated neuropathology.

abstract：:The postnatal development of the terminal Schwann cell, an analogue of the lamellar cell in cutaneous sensory receptors, was examined by histochemistry for non-specific cholinesterase and immunohistochemistry for S-100 protein in the periodontal Ruffini endings of the rat incisor. Double immunohistochemistry for S-100...

journal_title：Brain research

authors： Hayashi S,Nakakura-Ohshima K,Ohshima H,Noda T,Honma S,Wakisaka S,Maeda T

更新日期：2000-03-06 00:00:00

abstract：:In a previous study, we demonstrated that cholera toxin-A subunit, as well as the whole toxin, selectively blocks opioid-induced prolongation of the Ca2+ component of the action potential duration (APD) in dorsal root ganglion (DRG) neurons, indicating mediation of this excitatory effect by Gs-linked opioid receptors....

journal_title：Brain research

authors： Shen KF,Crain SM

更新日期：1990-10-29 00:00:00

abstract：:The effect of electrical stimulation of the prefrontal cortex (PFC) on acetylcholine (ACh) release in the dorsal striatum was investigated using on line in vivo microdialysis. ACh output was sampled before, during and after 20-min periods of 50 and 100 microA stimulation in awake, unrestrained rats. Both currents incr...

journal_title：Brain research

authors： Taber MT,Fibiger HC

更新日期：1994-03-14 00:00:00

abstract：:The possibility that the opioid delta-receptor mediates antinociception in tests where heat is the noxious stimulus was investigated using highly selective mu- and delta-agonist and -antagonists. Antinociceptive dose-response curves were constructed for mu ([D-Ala2,NMePhe4,Gly-ol]enkephalin, DAGO; morphine) and delta ...

journal_title：Brain research

authors： Heyman JS,Mulvaney SA,Mosberg HI,Porreca F

更新日期：1987-09-08 00:00:00

abstract：:In the brain, the neuropeptide cholecystokinin (CCK) appears to be involved in the mediation of stress responses. Here we provide new evidence that mild stress induces long-term changes in CCK-like immunoreactivity (CCK-LI) in the prefrontal cortex (PFC). The changes in CCK-LI show a biphasic pattern, with a decrease ...

journal_title：Brain research

authors： Radu D,Brodin E,Weber G,Lindefors N

更新日期：2001-07-27 00:00:00

abstract：:Lesions of the anterior hypothalamus-medial preoptic area (AH-MPOA) impair courtship and copulatory behavior in male Cnemidophorus inornatus, a sexually reproducing species of whiptail lizard, and male-like pseudosexual behaviors in C. uniparens, an all-female species. These results suggest that, since C. inornatus is...

journal_title：Brain research

authors： Kingston PA,Crews D

更新日期：1994-04-18 00:00:00

abstract：:Angiotensin peptides are thought to act as neurotransmitters or neuromodulators in central osmoregulation. We tested the hypothesis that angiotensin peptides are released in the paraventricular nucleus (PVN) of the hypothalamus upon local osmotic stimulation. Brain microdialysis and radioimmunoassay (RIA) techniques w...

journal_title：Brain research

authors： Qadri F,Edling O,Wolf A,Gohlke P,Culman J,Unger T

更新日期：1994-02-21 00:00:00

abstract：:The purpose of this study was to determine whether treatment with high-dose human serum albumin (HSA) would offer protection in a model of high-grade transient forebrain ischemia. Twenty-six fasted Wistar rats underwent bilateral common carotid artery occlusion and severe hypotension (50 mmHg) for 10 min. The agent (2...

journal_title：Brain research

authors： Belayev L,Saul I,Huh PW,Finotti N,Zhao W,Busto R,Ginsberg MD

更新日期：1999-10-16 00:00:00

abstract：:Transgenic mice expressing human APPswe and PS1-A264E mutations mimic certain neuropathological features of Alzheimer's disease (AD). These mice have elevated levels of the highly fibrillogenic amyloid beta1-42 peptide (Abeta42) and develop amyloid plaques around the age of 9 months. Our aim was to find whether these ...

journal_title：Brain research

authors： Wang J,Ikonen S,Gurevicius K,van Groen T,Tanila H

更新日期：2002-07-12 00:00:00

abstract：:Visuomotor behavior and pattern discrimination were studied in a group of cats raised with one eye closed by eyelid suturing 7-10 days after birth. At the age of 8-10 months the animals were forced to use their deprived eye by reversal of eye closure (closing the normal eye and opening the deprived one). Visuomotor be...

journal_title：Brain research

authors： Hof-Van Duin JV

更新日期：1976-07-30 00:00:00

abstract：:The effects of retinoic acid (RA), a naturally occurring metabolite of vitamin A, on the growth, morphology and neurochemical differentiation of the PC12 clone of rat pheochromocytoma cells were investigated. RA added to the medium inhibited the growth of PC12 cells in a dose-dependent manner up to 10 microM without a...

journal_title：Brain research

authors： Matsuoka I,Mizuno N,Kurihara K

更新日期：1989-11-13 00:00:00

abstract：:In recent decades, an increasing number of neuroimaging studies utilizing magnetic resonance imaging (MRI) have explored the differential effects of postherpetic neuralgia (PHN) on brain structure and function. We systematically reviewed and integrated the findings from relevant neuroimaging studies in PHN patients. A...

journal_title：Brain research

authors： Tang Y,Wang M,Zheng T,Xiao Y,Wang S,Han F,Chen G

更新日期：2021-02-01 00:00:00

abstract：:In vivo microdialysis combined with high performance liquid chromatography (HPLC) with electrochemical detection, was used to study the effect of MK-801 (0.1 mg/kg i.p.) on extracellular concentrations of dopamine (DA) 3,4-dihydroxyphenylacetic acid (DOPAC), serotonin (5-HT), norepinephrine (NE) and DOPAC/DA ratio in ...

journal_title：Brain research

authors： Hatip-Al-Khatib I,Mishima K,Iwasaki K,Fujiwara M

更新日期：2001-05-25 00:00:00

abstract：:7-Chlorokynurenic acid (7-Cl KYNA) has been reported to attenuate N-methyl-D-aspartate (NMDA) receptor functioning by a potent and selective inhibitory action mediated at the strychnine-insensitive glycine recognition site of the NMDA complex. Here we report that 7-Cl KYNA dose-dependently inhibits [3H]MK-801 binding ...

journal_title：Brain research

authors： Sircar R,Frusciante MJ,Javitt DC,Zukin SR

更新日期：1989-12-18 00:00:00

abstract：:Membrane properties of rat magnocellular neuroendocrine cells (MNCs) were examined during intracellular recordings in vivo. Current-clamp experiments revealed sustained outward rectification positive to -55 mV and transient outward rectification of depolarizing responses elicited from negative holding potentials. Trai...

journal_title：Brain research

authors： Bourque CW,Renaud LP

更新日期：1991-02-01 00:00:00

abstract：:Horseradish peroxidase (HRP) was used as a retrograde tracer to identify the distribution pattern of labeled cells in the inferior olivary nucleus (IO) of Tupaia. Crystallized HRP was implanted into dorsal (DPML) and ventral (VPML) divisions of the paramedian lobule (PML) and, following appropriate survival times, the...

journal_title：Brain research

authors： Whitworth RH Jr,Haines DE,Patrick GW

更新日期：1984-07-09 00:00:00

abstract：:Freeze-fracture examination of nodes of Ranvier from adult rat optic nerve demonstrates the presence of astrocytic processes at the majority of nodes of Ranvier. Astrocytic processes often run along the entire length of the nodal gap, although they do not necessarily encircle the entire nodal circumference. The E- and...

journal_title：Brain research

authors： Waxman SG,Black JA

更新日期：1984-08-06 00:00:00

abstract：:Tyrosine hydroxylase (TH) in freshly prepared 45,000 g supernatant from rat striatum was fractionated by DEAE-cellulose chromatography. The elution was made with 2 vols. of buffer (50 mM Tris, pH 7.4; 2 mM dithiothreitol) followed by 4 vols. of a linear NaCl gradient (0 0.3 M) in the same buffer. TH activity was elute...

journal_title：Brain research

authors： Sze PY,Alderson RF,Hedrick BJ

更新日期：1983-05-23 00:00:00

abstract：:The ionic mechanism of the membrane permeability changes caused by L-glutamate in hippocampal neurons prepared from 17- to 19-day-old fetal rat in dispersed cell cultures was studied with the whole-cell variation of the patch electrode voltage-clamp technique. The cultured hippocampal neurons became sensitive to gluta...

journal_title：Brain research

authors： Ozawa S,Nakamura T,Yuzaki M

更新日期：1988-03-08 00:00:00

abstract：:In the present study we have examined the effects of changes in potassium and calcium concentration on the early adaptation of the slowly adapting stretch receptor of the crayfish using intracellular recordings including the potential clamp technique. This was because previous studies had suggested that the early adap...

journal_title：Brain research

authors： Ottoson D,Swerup C

更新日期：1985-06-10 00:00:00

abstract：:The expression of the neurofilament (NF) protein triplet (70, 150 and 200 k daltons (K)) was studied by immunofluorescence in two clones of murine C-1300 neuroblastoma. Clone 1 formed clumps of round cells with few processes, while in clone 2 the cells were more dispersed and extended many processes. In both clones se...

journal_title：Brain research

authors： Dahl D,Rustigian R,Bignami A

更新日期：1984-05-14 00:00:00

abstract：:This study addressed the issue of multiple parallel auditory processing systems and their relationship to the skull-recorded auditory evoked potentials (AEPs) in the unanesthetized, unrestrained rat. In the preceding paper (Brain Res., 602 (1993) 240-250) it has been shown that auditory cortex activity does not contri...

journal_title：Brain research

authors： Simpson GV,Knight RT

更新日期：1993-02-05 00:00:00

abstract：:Previous studies in this laboratory have demonstrated that cholinergic receptors within the spinal cord play an important role in the expression of naloxone-precipitated withdrawal symptoms in the morphine-dependent rat. Related cardiovascular studies in non-dependent animals have demonstrated that this spinal choline...

journal_title：Brain research

authors： Buccafusco JJ,Terry AV Jr,Shuster L

更新日期：1995-05-15 00:00:00

abstract：:Endothelins are potent vasoconstrictors and signaling molecules. Their effects are broad, impacting processes ranging from neurovascular and cardiovascular health to cell migration and survival. In stroke, traumatic brain injury or subarachnoid hemorrhage, endothelin-1 (ET-1) is induced resulting in cerebral vasospasm...

journal_title：Brain research

authors： Bickford JS,Ali NF,Nick JA,Al-Yahia M,Beachy DE,Doré S,Nick HS,Waters MF

更新日期：2014-11-07 00:00:00

abstract：:When rabbit retinas are exposed in vitro to specific excitatory amino acid receptor agonists certain GABAergic amacrine cells are activated to cause a release of GABA. The GABA that is not released can be detected by immunohistochemistry. Exposure of tissues to kainate or NMDA each caused a characteristic change in th...

journal_title：Brain research

authors： Osborne NN,Pergande G,Block F,Schwarz M

更新日期：1994-12-26 00:00:00

abstract：:Techniques to induce activity-dependent neuronal plasticity in vivo allow the underlying signaling pathways to be studied in their biological context. Here, we demonstrate activity-induced plasticity at neuromuscular synapses of Drosophila double mutant for comatose (an NSF mutant) and Kum (a SERCA mutant), and presen...

journal_title：Brain research

authors： Freeman A,Bowers M,Mortimer AV,Timmerman C,Roux S,Ramaswami M,Sanyal S

更新日期：2010-04-22 00:00:00

abstract：:In non-neuronal cultures of cells dissociated from postnatal rat cerebellum astrocytes, identified by the presence of the marker protein glial fibrillary acidic protein (GFAP), displayed two distinct morphological forms. One class was stellate in shape with radially distributed fine processes, while the other class wa...

journal_title：Brain research

authors： Wilkin GP,Levi G,Johnstone SR,Riddle PN

更新日期：1983-11-01 00:00:00

abstract：:Until now, there has been no effective therapy for chronic sensorineural hearing impairment. This study investigated the role of bone marrow cells (BMCs) in cochlear dysfunction. BALB/c mice (2 months of age), a non-presbycusis-prone mouse strain, were lethally irradiated and then transplanted with BMCs from SAMP1 mic...

journal_title：Brain research

authors： Baba S,Iwai H,Inaba M,Kawamoto K,Omae M,Yamashita T,Ikehara S

更新日期：2006-11-20 00:00:00

abstract：:The [14C]2-deoxy-D-glucose technique was used to test the effects of central muscarinic stimulation on local cerebral glucose utilization (LCGU) in rats. Systemic administration of the muscarinic agonist oxotremorine (OXO, 0.7 mg/kg, ip) increased LCGU in brain regions involved in motor function: the sensorimotor cort...

journal_title：Brain research

authors： Dow-Edwards D,Dam M,Peterson JM,Rapoport SI,London ED

更新日期：1981-12-07 00:00:00

abstract：:Gastrin-releasing peptide (GRP) mediated signals in the central nervous system (CNS) influence many functions associated with energy metabolism. The purpose of the present study was to investigate the central effect of GRP on glucose metabolism in the male rat. Intracerebroventricular (icv) administration of GRP cause...

journal_title：Brain research

authors： Jha PK,Foppen E,Challet E,Kalsbeek A

更新日期：2015-11-02 00:00:00