Abstract：
:Responses to rotation in many vertical and horizontal planes were studied in electrically identified secondary vestibular neurons of alert cats. This report concerns secondary neurons that gave responses which could not be explained as due to a summation of semicircular canal inputs. These cells responded to sinusoidal rotation of the cat in any vertical plane, and response phase depended on the plane of rotation. The responses were modeled as the result of summation of two inputs that differed in their spatial orientations and dynamics. Response dynamics and a comparison of responses to vertical and horizontal rotations showed that some cells were sensitive to rotation with respect to gravity. Their responses both to gravity and horizontal rotations argue that these secondary neurons received convergent otolith and canal inputs. Some cells also had oculomotor related discharges and/or responded weakly to neck rotation.
journal_name
Brain Resjournal_title
Brain researchauthors
Baker J,Goldberg J,Hermann G,Peterson Bdoi
10.1016/0006-8993(84)91318-0subject
Has Abstractpub_date
1984-02-27 00:00:00pages
138-43issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(84)91318-0journal_volume
294pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Short-term potentiation of extracellular field excitatory postsynaptic potentials (EPSP's) was investigated in the stratum radiatum of CA1 of the rat hippocampal slice in vitro. A presynaptic tetanus consisting of a single train of stimuli at 250 Hz evoked short-term potentiation (STP), but not long-term potentiation ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90304-6
更新日期：1988-08-30 00:00:00
abstract：:The neuroactive steroid 5 beta-pregnan-3 alpha-ol-20-one (5 beta 3 alpha) modulates GABAA receptor function by potentiating postsynaptic GABA currents. While much is now known about the postsynaptic action of neurosteroids, far less is known about how they affect neurotransmission. We have investigated the synaptic ac...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00809-3
更新日期：1997-10-03 00:00:00
abstract：:Adaptive behaviour requires that organisms continuously monitor the environment for potentially significant information and evaluate whether currently unattended stimuli afford a behavioural change. Here we used event-related functional magnetic resonance imaging in humans to assess the neural mechanisms underlying th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.06.056
更新日期：2010-09-10 00:00:00
abstract：:17β-Estradiol is a multi-active steroid that imparts neuroprotection via diverse mechanisms of action. However, its role as a neuroprotective agent after spinal cord injury (SCI), or the involvement of the estrogen receptor-alpha (ER-α) in locomotor recovery, is still a subject of much debate. In this study, we evalua...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2014.03.002
更新日期：2014-05-02 00:00:00
abstract：:Ibotenic acid lesions of the vertical limb of the diagonal band of Broca (VDB) in marmosets produced significant depletions in choline acetyltransferase (ChAT) activity and a decrease in acetylcholinesterase (AChE) staining in the hippocampal formation and entorhinal cortex (to which the cholinergic neurones of the VD...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90348-4
更新日期：1988-07-19 00:00:00
abstract：:Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors and are considered promising therapeutic targets in several neurodegenerative diseases. A number of PPAR agonists have been shown to have neuroprotective properties in the presence of oxidative stress, neuroinflammatory response, and apoptosis i...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2018.09.036
更新日期：2019-02-01 00:00:00
abstract：:Previous neuroimaging studies provided evidence that visual mental imagery relies, in part, on the primary visual cortex. We hypothesized that, analogous to the finding that motor imagery increases the excitability of motor cortex, visual imagery should increase visual cortex excitability, as indexed by a decrease in ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)02478-2
更新日期：2002-05-31 00:00:00
abstract：:Prenatal exposure to chlorpyrifos (CPF) leads to cognitive impairments in adulthood. The cytoarchitectural basis is unclear. In the present study, we assessed the effects of prenatal CPF exposure on T-maze delayed alternation task and the win-shift/lose-shift responses associated with the morphology of the dorsal hipp...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2012.07.036
更新日期：2012-09-20 00:00:00
abstract：:Mammalian transglutaminases (TGs) catalyze the irreversible post-translational modifications of proteins, the most prominent of which is the calcium-dependent formation of covalent acyl transfers between the γ-carboxamide group of glutamine and the ε-amino-group of lysine (GGEL-linkage). In the central nervous system,...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.11.027
更新日期：2016-01-15 00:00:00
abstract：:Levodopa (L-DOPA) is widely used for symptomatic management in Parkinson's disease. We recently showed that (-)-epigallocatechin-3-gallate, a tea polyphenol, not only inhibits L-DOPA methylation, but also protects against oxidative hippocampal neurodegeneration. In the present study, we sought to determine several oth...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2012.11.043
更新日期：2013-02-25 00:00:00
abstract：:Cyclooxygenase-2 (COX-2) is the predominant isoform of cyclooxygenase in brain. COX-2 activity produces oxidative stress and results in the production of prostaglandins that have many injurious effects. COX-2 transcription is induced by synaptic activity; therefore, COX-2 activity could contribute to epileptic neurona...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.05.038
更新日期：2005-07-19 00:00:00
abstract：:Experiments were carried out on UC-11MG human astrocytoma cells, a continuous cell line that expresses a broad range of the biochemical and electrophysiological properties found in well-differentiated astrocytes. Because of a number of recent reports that astrocytes may express receptors for a variety of neuro-active ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91676-6
更新日期：1992-10-02 00:00:00
abstract：:The retrogradely-transported tracer, rhodamine-tagged microspheres was injected into the pressor region of the rostral ventrolateral medulla (RVLM) to enable detection of paraventricular neurons in the hypothalamus that project to the RVLM. The protein, Fos, was detected immunohistochemically and used to highlight neu...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00560-5
更新日期：1998-08-10 00:00:00
abstract：:Sites which bind oxytocin and vasopressin with high affinity were detected in the brain and upper spinal cord of 12 human subjects, using in vitro light microscopic autoradiography. Tissue sections were incubated with tritiated vasopressin, tritiated oxytocin or an iodinated oxytocin antagonist. The ligand specificity...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90345-v
更新日期：1991-08-02 00:00:00
abstract：:The present study determined whether cortical cholinergic neurons recover functionally following the loss of afferent projections from the nucleus basalis magnocellularis (nbm). At various time points following ibotenic acid lesions of the nbm, choline acetyltransferase (ChAT) activity or the capacity of cortical chol...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90904-2
更新日期：1993-06-11 00:00:00
abstract：:The ionic basis of norepinephrine (NE) action was studied with intracellular recording techniques in the rat hippocampal slice. Topical application of NE caused, in CA1 neurons, a 3-4 mV hyperpolarization associated with a 10-20% decrease in input resistance. This effect was accompanied by a decrease in spontaneous ac...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90104-9
更新日期：1981-02-09 00:00:00
abstract：BACKGROUND:It is unclear whether spinal cord stimulation (SCS) at higher frequencies induces further increases in vasodilation and enhances clinical efficacy. OBJECTIVES:This study investigated effects of SCS at both a normal frequency (as used clinically) and two higher frequencies on peripheral vasodilation. METHOD...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.11.072
更新日期：2010-02-08 00:00:00
abstract：:Brain injury accelerates amyloid-β (Aβ) deposits and exacerbates Alzheimer's disease (AD). Accumulation of intracellular soluble Aβ impairs cognition prior to emergence of Aβ plaques. However, it is not known whether brain injury affects learning impairment attributable to intracellular soluble Aβ. We made a small inj...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2016.02.017
更新日期：2016-04-15 00:00:00
abstract：:To determine the contribution of presynaptic cholinergic mechanisms to the increased sensitivity of a genetically selected line of Sprague-Dawley rats (Flinders S-line) to the anticholinesterase, diisopropyl fluorophosphate (DFP), rats were sacrificed by focused microwave irradiation of the head 1 min after a pulse in...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)91044-8
更新日期：1984-03-05 00:00:00
abstract：:Our recent study has shown that many afferent fibers in the ventral root are third branches of dorsal root ganglion cells in addition to their processes in the peripheral nerve and the dorsal root. From results of this study, we hypothesized that most of the afferent fibers in the normal ventral root are extra process...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)91030-5
更新日期：1989-10-30 00:00:00
abstract：:Morphine is one of the most potent analgesics used in medicine and it's long-term use is associated with the risk of the state of dependence. The cessation of chronic morphine administration leads to withdrawal signs which are associated with neurotransmitter dysregulations within mesolimbic system. Adenosine 5'-triph...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2019.05.025
更新日期：2019-09-15 00:00:00
abstract：:The entire set of giant interneurons (GIs) in the nerve cord of the cockroach, Periplaneta americana, was ablated using either electrolytic or surgical techniques. All animals with these lesions were capable of turning and running away from standard wind puffs. However, all animals responded much less frequently to st...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)91202-4
更新日期：1988-04-05 00:00:00
abstract：:Sleep-suppressive activity of prostaglandin synthesis inhibitors, diclofenac sodium (DF) and indomethacin (IM), was examined in unrestrained male rats. An intraperitoneal injection of 5 mg/kg IM, or an oral administration of 5 mg/kg DF and 10 mg/kg IM at an early phase of the light period transiently decreased slow wa...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90173-4
更新日期：1988-06-21 00:00:00
abstract：:Previous observations show that neonatal removal of nerve growth factor results in an increased number of fine dorsal root axons in the adult animal. The present study shows that the same treatment results in 49% more axons in the adult tract of Lissauer, which is an area of spinal white matter that contains predomina...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90262-4
更新日期：1988-10-04 00:00:00
abstract：:William James noted that memories could persist from minutes to weeks. This essay attempts to explain this variation by situating the explanation in the biochemistry of dendritic spines. Two outcomes are critical to generate the synaptic basis of memory: (1) the actin cytoskeleton in the spine must be degraded to perm...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2014.12.009
更新日期：2015-09-24 00:00:00
abstract：:Previous studies have shown that long-term 5-hydroxytryptamine (5-HT) depletion induced by combined dorsal and median raphe injections of 5,7-dihydroxytryptamine (5,7-DHT) leads to impairments in the acquisition and performance of behaviour maintained under a differential-reinforcement-of-low-rate (DRL) schedule of re...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)00037-q
更新日期：1995-03-27 00:00:00
abstract：:The distribution of NK(1) receptor immunoreactivity in the amygdaloid complex, induction of NK(1) receptor endocytosis in the amygdala following immobilisation stress, and the ability of pretreatment with the substance P antagonist L-760,735 or imipramine to block this response were examined in gerbils, a species with...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01976-9
更新日期：1999-11-27 00:00:00
abstract：:The efficacy of 5 alpha-androstane-3 alpha,17 beta-diol (3 alpha-Androstanediol; 3 alpha-Diol) and 4-pregnen-3,20-dione (progesterone; P) in promoting analgesia was investigated. Ovariectomized rats received daily injections of 3 alpha-Diol (0.6, 3.0, 6.0 and 7.5 mg/kg) or vehicle and twice daily injections of estradi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)01118-8
更新日期：1996-02-12 00:00:00
abstract：:Cholinergic mechanisms in the septohippocampal pathway contribute to several cognitive functions and impaired cholinergic transmission in this pathway may be related to the memory loss and dementia that accompanies normal aging and Alzheimer's disease and behavioral studies suggest that muscarinic mechanisms in the me...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00729-x
更新日期：1998-09-14 00:00:00
abstract：:The primary mechanism of action of bupropion, a smoking cessation drug, is commonly believed to involve the dopaminergic system although evidence exists that bupropion also has effects at nicotinic acetylcholine receptors (nAChRs). This study evaluated the disruptive effects of nicotine on response rates in the presen...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.07.110
更新日期：2006-10-30 00:00:00
