The rostral projection of small diameter primary afferents in Lissauer's tract.

abstract：:Ouabain binds to the catalytic subunit of Na+,K+-ATPase and specific [3H]ouabain binding can be used as a measure of the number of active enzyme molecules present in a given tissue. Specific [3H]ouabain binding can be demonstrated in frozen, cryostat sections from rat brain and pineal and these sites have the characte...

journal_title：Brain research

authors： Caspers ML,Schwartz RD,Labarca R,Paul SM

更新日期：1987-04-21 00:00:00

abstract：:5-Hydroxytryptamine (5-HT, serotonin), synthesized in midbrain raphe nuclei and released in various hypothalamic sites, decreases food intake but the specific 5-HT receptor subtypes involved are controversial. Here, we have studied changes in the regional density of binding to 5-HT receptors and transporters and the l...

journal_title：Brain research

authors： Park S,Harrold JA,Widdowson PS,Williams G

更新日期：1999-11-13 00:00:00

abstract：:The present study attempts to elucidate the possible role of adenosine 3',5'-monophosphate (cAMP) and prostaglandin E2 (PGE2) in the function of the neural luteinizing hormone-releasing hormone (LH-RH) apparatus. To this end, in vitro LH-RH release from superfused hypothalamic fragments and cAMP production by hypothal...

journal_title：Brain research

authors： Kim K,Ramirez VD

更新日期：1986-10-29 00:00:00

abstract：:Light microscopic double labeling immunocytochemistry for vasoactive intestinal peptide (VIP) and gonadotrophin-releasing hormone (GnRH) was carried out on the hypothalami of male and female rats. It was found that the number of VIP boutons that terminate on GnRH neurons and the percentage of GnRH neurons contacted by...

journal_title：Brain research

authors： Horvath TL,Cela V,van der Beek EM

更新日期：1998-06-08 00:00:00

abstract：:We observed chronological changes of platelet endothelial cell adhesion molecule-1 (PECAM-1), final mediator of neutrophil transendothelial migration, immunoreactivity, and protein level in the gerbil hippocampus proper after 5 min of transient ischemia. One day after ischemic insult, PECAM-1 immunoreactivity and prot...

journal_title：Brain research

authors： Hwang IK,Kim DW,Yoo KY,Jung BK,Song JH,Jung JY,Choi SY,Kang TC,Lee JY,Kwon YG,Won MH

更新日期：2005-06-28 00:00:00

abstract：:A histo-enzymatic technique for visualizing and quantifying endogenous NAD(H) in brain tissue was developed, based on coupled enzymatic cycling reactions that reduce nitrotetrazolium blue chloride to produce formazan. Conditions were used where the endogenous level of nicotinamide adenine dinucleotides (NAD(H)) was th...

journal_title：Brain research

authors： Balan IS,Fiskum G,Kristian T

更新日期：2010-02-26 00:00:00

abstract：:Ischemic-reperfusion injury in humans occurs in conditions such as stroke, cardiac arrest, subarachnoid hemorrhage or head trauma. Maximal tissue damage is observed during reperfusion, which is primarily attributed to oxidative injury resulting from production of oxygen free radicals. One of the major consequences of ...

journal_title：Brain research

authors： Panigrahi M,Sadguna Y,Shivakumar BR,Kolluri SV,Roy S,Packer L,Ravindranath V

更新日期：1996-04-22 00:00:00

abstract：:Expression of the immediate-early gene c-fos, a marker of neuronal activation, was employed to localize brainstem neuronal populations functionally related to the expiration reflex (ER). Twelve spontaneously breathing, non-decerebrate, pentobarbital anesthetized cats were used. The level of Fos-like immunoreactivity (...

journal_title：Brain research

authors： Poliacek I,Halasova E,Jakus J,Murin P,Barani H,Stransky A,Bolser DC

更新日期：2007-12-12 00:00:00

abstract：:The present study aimed to evaluate the therapeutic potential of apocynin, an NADPH oxidase assembly inhibitor, on traumatic brain injury. Rat traumatic brain injury (TBI) was performed using a weight drop model. Apocynin (100mg/kg) was injected into the intraperitoneal space 15 min before TBI. Reactive oxygen species...

journal_title：Brain research

authors： Choi BY,Jang BG,Kim JH,Lee BE,Sohn M,Song HK,Suh SW

更新日期：2012-10-24 00:00:00

abstract：:The L-isomer of beta-N-methylamino-L-alanine (BMAA), present in free form in seed of Cycas circinalis, elicits in spinal cord cultures a pattern of acute postsynaptic neuronal vacuolation comparable to that induced by beta-N-oxalylamino-L-alanine (BOAA), an excitotoxic amino acid of greater potency isolated from seed ...

journal_title：Brain research

authors： Nunn PB,Seelig M,Zagoren JC,Spencer PS

更新日期：1987-05-05 00:00:00

abstract：:The addition of L-glutamic acid (Glu) alone, both Glu and glycine (Gly) or Glu/Gly/spermidine (SPD) was effective in potentiating [3H]5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10- imine (MK-801) binding before equilibrium to an ion channel associated with the N-methyl-D-aspartate (NMDA) receptor complex in b...

journal_title：Brain research

authors： Yoneda Y,Enomoto R,Ogita K

更新日期：1994-02-14 00:00:00

abstract：:Calcium-binding proteins play a critical role in vertebrate sensory cells, and some of them have been detected in mechanosensory and chemosensory cells of bony and cartilaginous fishes. In this study immunohistochemistry and Western blot were used to investigate the occurrence and the distribution of S100 protein and ...

journal_title：Brain research

authors： Germanà A,Paruta S,Germanà GP,Ochoa-Erena FJ,Montalbano G,Cobo J,Vega JA

更新日期：2007-08-08 00:00:00

abstract：:To study morphological changes in the cortex that follow repeated ischemia, one, two, and three 7-min unilateral occlusions of the carotid artery at 6-h intervals, and three, four, and five 7-min similar occlusions at 12-h intervals were produced in gerbils. Animals with one and two 7-min occlusions at 6-h intervals s...

journal_title：Brain research

authors： Hanyu S,Ito U,Hakamata Y,Yoshida M

更新日期：1995-07-17 00:00:00

abstract：:The prostacyclin (PGI2) formation in cerebral vessels, as reflected by the difference in concentration of internal carotid arterial and internal jugular venous radioimmunoassayed 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha), was determined under normocapnic and hypercapnic conditions in 5 patients with mild cereb...

journal_title：Brain research

authors： Uyama O,Nagatsuka K,Fukunaga R,Kusunoki M,Takano T,Yoneda S,Kimura K,Abe H

更新日期：1983-01-24 00:00:00

abstract：:Ramified microglial cells were investigated in primary cultures of dissociated cerebral cortical tissue from rats. The identification of these cells was confirmed through immunohistochemical staining with 7 monoclonal antibodies selective for microglia. While there was significant variation in staining intensity with ...

journal_title：Brain research

authors： Booth PL,Thomas WE

更新日期：1991-05-10 00:00:00

abstract：:Retrogradely labeled vestibulo-ocular neurons (VOR) that also stain with antibodies for the excitatory amino acid neurotransmitters glutamate (GLU-LI) or aspartate (ASP-LI) were studied. VOR neurons that contained GLU-LI or ASP-LI label were identified in the medial (MVN) and superior (SVN) vestibular nuclei, and cell...

journal_title：Brain research

authors： Kevetter GA,Hoffman RD

更新日期：1991-07-19 00:00:00

abstract：:Endothelins are potent vasoconstrictors and signaling molecules. Their effects are broad, impacting processes ranging from neurovascular and cardiovascular health to cell migration and survival. In stroke, traumatic brain injury or subarachnoid hemorrhage, endothelin-1 (ET-1) is induced resulting in cerebral vasospasm...

journal_title：Brain research

authors： Bickford JS,Ali NF,Nick JA,Al-Yahia M,Beachy DE,Doré S,Nick HS,Waters MF

更新日期：2014-11-07 00:00:00

abstract：:The effects of ventromedial hypothalamic (VMH) stimulation on various metabolic parameters in freely moving animals were measured using a specific indirect calorimetric chamber associated with a quantitative measurement of locomotor activity, which allows the separate measurement of locomotor energy expenditure from t...

journal_title：Brain research

authors： Ruffin M,Nicolaidis S

更新日期：1999-10-30 00:00:00

abstract：:The effects of different ionic media on Ca2+ uptake and release in isolated brain microsomes were investigated. KCl (100 mM) provided the best medium for Ca2+ uptake in the presence of ATP. The effect of myo-inositol 1,4,5-trisphosphate (IP3) on Ca2+ release was examined and was maximum at 0.2 microM. IP3-induced Ca2+...

journal_title：Brain research

authors： Shah J,Cohen RS,Pant HC

更新日期：1987-09-01 00:00:00

abstract：:Spontaneous figure reversal of ambiguous patterns was analyzed in humans. A) With Necker-"cube"-like, or "drum"-like figures, having square or round shaped "front" and "rear" surfaces, and either large or small "depth", the perceptual intervals corresponding to both interpretations of "drum" were longer than those of ...

journal_title：Brain research

authors： Taddei-Ferretti C,Radilova J,Musio C,Santillo S,Cibelli E,Cotugno A,Radil T

更新日期：2008-08-15 00:00:00

abstract：:Extracellular action potentials were recorded from 691 neurons in the ventromedial hypothalamus (VMH) of urethane anesthetized female rats under acute and chronic sham-operated and hyperprolactinemic conditions. Hyperprolactinemia was produced by transplanting pituitaries under the kidney capsules. Neuronal excitabili...

journal_title：Brain research

authors： Moss RL,Chan A,Dudley CA

更新日期：1985-11-04 00:00:00

abstract：:Recent reports have suggested that the excitatory amino acid L-glutamate is a neurotransmitter released by baroreceptor afferent nerves at their termination in the nucleus tractus solitarii (NTS). In this study we have examined the effect on arterial pressure, heart rate and baroreflex activity of the glutamate antago...

journal_title：Brain research

authors： Talman WT,Perrone MH,Scher P,Kwo S,Reis DJ

更新日期：1981-07-27 00:00:00

abstract：:We identified cell bodies of a pair of the cardio-inhibitory (CI) neurons in the first thoracic ganglion (TG1) of Bathynomus doederleini. Each of the cell bodies gives rise to a single axon, which runs into the contralateral hemiganglion of TG1 via the commissure and runs to the heart via the fourth root as CI axon. S...

journal_title：Brain research

authors： Tanaka K,Kuwasawa K

更新日期：1991-09-06 00:00:00

abstract：:Homer1a is implicated in depression in humans and depression-like behavior in mice. To further understand the role of Homer1a in stress-induced emotional changes, we applied very mild stress to Homer1a knockout (H1a KO) mice. The wild-type (WT) and H1a KO mice were restrained for 2h daily for 7 consecutive days at the...

journal_title：Brain research

authors： Shui Y,Wang L,Luo X,Uchiumi O,Yamamoto R,Sugai T,Kato N

更新日期：2015-04-24 00:00:00

abstract：:The effects of medial septal lesions on latent inhibition (LI) were assessed in a conditioned taste aversion paradigm. Animals were tested in a LI paradigm 2 weeks after receiving medial septal or sham lesions. The LI paradigm involved a pre-exposure phase in which water-deprived rats were allowed access to either wat...

journal_title：Brain research

authors： Turgeon SM,Kegel G,Davis MM

更新日期：2001-02-02 00:00:00

abstract：:Horseradish peroxidase (HRP) histochemistry was used to study the time course of reinnervation of the pigeon olfactory bulb after simple transection of the primary olfactory nerve. At selected intervals (9, 13, 29, 61 and 93 days) after transection of the right olfactory nerve, a concentrated solution of HRP was insti...

journal_title：Brain research

authors： Jennings RA,Hambright Keiger CJ,Walker JC

更新日期：1995-06-19 00:00:00

abstract：:Neurons are distinctive in that they are generally considered to be permanently post-mitotic cells. The oncoprotein p53 is a key regulator in neuronal development, notably in cell proliferation and neuronal death. We hypothesize that p53 maintains the post-mitotic characteristic of differentiated neurons. New lines of...

journal_title：Brain research

authors： Miller MW,Peter A,Wharton SB,Wyllie AH

更新日期：2003-03-07 00:00:00

abstract：:The [14C]2-deoxyglucose (2-DG) technique has been widely utilized for quantitative measurement of local cerebral metabolic for glucose (1CMRG) in animals. The technique as presently used is limited by the energy of 14C beta-particles, which can travel relatively great distances in tissue. This results in limited audio...

journal_title：Brain research

authors： Alexander GM,Schwartzman RJ,Bell RD,Yu J,Renthal A

更新日期：1981-10-26 00:00:00

abstract：:The rapid saltatory motion of intra-axonal particles detected by dark-field microscopy in myelinated axons isolated from sciatic nerves of adult Xenopus laevis was inhibited by colchicine or vinblastine at a concentration of larger than or equal to 0.1 mM. Both the predominant somatopetal transport and the somatofugal...

journal_title：Brain research

authors： Hammond GR,Smith RS

更新日期：1977-06-10 00:00:00

abstract：:The biosynthetic activity of extra-hypothalamic vasopressin (VP) neurons in the bed nucleus of the stria terminalis (BNST) is regulated by gonadal steroids. These neurons have also been implicated in a number of behaviors that are impaired in aging. We previously reported that VP mRNA labelling in the BNST is decrease...

journal_title：Brain research

authors： Dobie DJ,Miller MA,Raskind MA,Dorsa DM

更新日期：1992-06-26 00:00:00