Abstract：
:The prostacyclin (PGI2) formation in cerebral vessels, as reflected by the difference in concentration of internal carotid arterial and internal jugular venous radioimmunoassayed 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha), was determined under normocapnic and hypercapnic conditions in 5 patients with mild cerebral thrombotic infarction. There was no evidence that endogenous PGI formation in cerebral vessels was stimulated at mild hypercapnia, while an increase of cerebral blood flow (CBF) induced by hypercapnia was observed. These results suggest that endogenous PGI2 may not be a mediator for the response of CBF to CO2.
journal_name
Brain Resjournal_title
Brain researchauthors
Uyama O,Nagatsuka K,Fukunaga R,Kusunoki M,Takano T,Yoneda S,Kimura K,Abe Hdoi
10.1016/0006-8993(83)91272-6subject
Has Abstractpub_date
1983-01-24 00:00:00pages
344-7issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(83)91272-6journal_volume
259pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:We have previously demonstrated that ibotenate (IBO)-stimulated polyphosphoinositide (PPI) hydrolysis is increased for a long period in the amygdala/pyriform cortex (AM/PC) of amygdala (AM)- and hippocampal (HIPP)-kindled rats. This finding indicates that enhanced function of the PPI-coupled excitatory amino acid (EAA...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90370-o
更新日期：1992-01-08 00:00:00
abstract：:Insulin has emerged as an important neuropeptide. Central actions of insulin appear to oppose those in the periphery. Insulin is transported across the blood-brain barrier (BBB) by a saturable transport system. The permeability of the BBB to insulin is altered by various events, but no studies exist that have examined...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)03247-9
更新日期：2001-03-30 00:00:00
abstract：:(1) Synaptic transmission was studied in isolated transverse hippocampal slices from guinea pigs. Extracellular evoked potentials were recorded in the region CA1. (2) Changing the normal perfusion solution (containing 2 mM Ca2+) to calcium-free Ringer abolished synaptic transmission which was again restored by adding ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)91327-x
更新日期：1980-07-21 00:00:00
abstract：:Using an isolated neonatal rat spinal cord preparation, we have studied the ability of hydrogen peroxide to act as a source of oxygen for mammalian central nervous system (CNS) maintained in vitro. We report here that hydrogen peroxide, in low concentrations (0.001-0.004%), can effectively provide the only source, or ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90280-9
更新日期：1983-11-14 00:00:00
abstract：:Previous findings from this laboratory demonstrating changes in dopamine (DA) transporter and D2 receptors in the amygdaloid complex of subjects with major depression indicate that disruption of dopamine neurotransmission to the amygdala may contribute to behavioral symptoms associated with depression. Quantitative re...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.02.009
更新日期：2008-05-01 00:00:00
abstract：:The recent indications of specialized lateralization of cardiovascular regulation within the right and left posterior insular cortex of the rat, suggest the possibility of transcallosal connectivity between these regions. This has not been previously demonstrated using physiological techniques. Extracellular neural re...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02068-0
更新日期：2000-04-28 00:00:00
abstract：:We used rabbit antisera against manganese (Mn)-superoxide dismutase for immunohistochemical studies of localization in the rat neostriatum. Immunostaining was intense in large-sized neurons and several medium-sized neurons, but it was moderate to weak in other cells. Double immunostaining with monoclonal antibody to c...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90618-6
更新日期：1991-05-17 00:00:00
abstract：:The substance P and Met-enkephalin content were measured in the rat lumbar spinal cord after monolateral section of the sciatic nerve. The proximal stump of the lesioned nerve was either ligated, limiting the formation of neuroma, or sutured intraperitoneally, allowing the formation of a very large neuroma. Both types...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91147-3
更新日期：1985-09-09 00:00:00
abstract：:The behavioral effects of lesions of the nucleus basalis magnocellularis (NBM) on two spatial discrimination tasks (place navigation and cross maze) were examined in the rat. These tasks were designed to test reference memory. Lesions by bilateral injection of ibotenic acid into the NBM led to a severe and permanent i...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90079-0
更新日期：1988-07-12 00:00:00
abstract：:The jimpy gene is a sex-linked recessive mutation which produces severe hypomyelination throughout the central nervous system (CNS) in affected male mice. The female carrier also expresses the mutation, but the degree of hypomyelination varies considerably among the tracts. In the optic nerve, patches of unmyelinated ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90958-1
更新日期：1982-10-28 00:00:00
abstract：:C3H/HeJ mice are refractory to lipolysaccharide (LPS) in the periphery, primarily because their macrophages do not respond to LPS and produce pro-inflammatory cytokines such as interleukin-1 (IL-1). To determine if they are also refractory to LPS in the brain, behavior of C3H/HeJ mice was compared to LPS-sensitive C3H...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(96)01454-0
更新日期：1997-03-28 00:00:00
abstract：:Rats showing disrupted taste aversion due to gustatory neocortex or amygdala lesions were transplanted into the lesioned area with homologous brain tissue obtained from 17-day-old fetuses. Comparisons of taste aversions scores before and after the graft, revealed that the grafted animals significantly recuperated tast...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)91507-1
更新日期：1987-07-21 00:00:00
abstract：:In this study, a single unit activity was recorded in the nucleus paragigantocellularis (PGi), located in the rostral ventrolateral medulla of anesthetized, morphine-dependent rats. The spontaneous activity of PGi neurons was significantly decreased by administration of morphine (10 mg/kg; i.p.) in sham-operated, cont...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)01029-4
更新日期：1998-12-14 00:00:00
abstract：:Pharmacological characteristics of native neuronal nicotinic acetylcholine receptor-mediated ion currents in mouse N1E-115 neuroblastoma cells have been investigated by superfusion of voltage clamped cells with known concentrations of the agonists acetylcholine, nicotine and cytisine, and the antagonists alpha-bungaro...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90493-6
更新日期：1994-08-22 00:00:00
abstract：:The phenomenon of ischemic tolerance has been closely associated with the expression of heat shock proteins but recently, stress tolerance not related to hsp72 has been reported. In the present study, we focused on ischemic tolerance induced by hypoxia and hyperthermia in neonatal rat brain and analyzed the expression...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)02036-3
更新日期：1999-11-20 00:00:00
abstract：:Sustained seizure activity can be induced in rabbit olfactory bulb by application of brief low-level current via chronically implanted micro-electrodes. Sensitivity to such stimulation is markedly augmented by prior surgical isolation of the ipsilateral or contralateral bulb. The isolated rabbit olfactory bulb appar...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(75)90056-6
更新日期：1975-08-29 00:00:00
abstract：:Previous studies have shown that the feline caudate nucleus contains DPI-sensitive (caput nuclei caudati, anterodorsal part; r-CRM) and DPI-insensitive (caput nuclei caudati, rostromedial part; CRM) regions. Stimulation of dopamine receptors within the r-CRM by dopamine or DPI are known to elicit oro-facial dyskinesia...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90689-s
更新日期：1991-01-18 00:00:00
abstract：:Neurokinins, such as substance P (SP), modulate the reflex regulation of cardiovascular and respiratory function in the CNS, particularly in the nucleus tractus solitarius (NTS). There is considerable evidence of the action of SP in the NTS, but the precise effects have not yet been determined. Voltage-dependent Ca2+ ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.06.060
更新日期：2006-09-19 00:00:00
abstract：:Opioid modulation of ingestion includes general opioid antagonism of deprivation-induced water intake and intake of sucrose and saccharin solutions. Previous studies using selective subtype antagonists indicated that opioid effects upon deprivation-induced water intake occurred through the mu2 receptor and that opioid...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91274-v
更新日期：1993-08-06 00:00:00
abstract：:Although there are several reports on the alteration of intracellular signal transduction during heat shock in somatic cells, the long term effects of heat shock on neuronal cells remain unknown. In this report, we investigated cyclic AMP (cAMP) accumulation and the expression of heat shock proteins following heat sho...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00072-9
更新日期：1998-04-20 00:00:00
abstract：:We investigated the effects of pituitary adenylate cyclase-activating polypeptide (PACAP38) on cytosolic free calcium ([Ca2+]i) at a single cell level in both type-1 and type-2 cultured rat astrocytes using a calcium-sensitive fluorescent dye, fura-2. Type-1 astrocytes were relatively silent during the 20 min observat...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90790-0
更新日期：1994-10-31 00:00:00
abstract：:Significant insights into the dynamics of neuronal populations have been gained in the olfactory system where rich spatio-temporal dynamics is observed during, and following, exposure to odours. It is now widely accepted that odour identity is represented in terms of stimulus-specific rate patterning observed in the c...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.07.032
更新日期：2012-01-24 00:00:00
abstract：:Threohydroxyaspartate (THA)-induced glutamate excitotoxicity in organotypic culture of rat spinal cord is a well-known model of motor neuron degeneration. THA causes accumulation of synaptic glutamate and over stimulation of the postsynaptic receptor by inhibiting glutamate uptake. This model has also been used to ide...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.12.030
更新日期：2009-02-27 00:00:00
abstract：:The heterogeneous nature of vesicles has been studied by evaluating exocytotic events released from the cell body of a dopamine-containing neuron of Planorbis corneus. Vesicular exocytosis has been elicited by stimulation with in situ application of elevated potassium and has been monitored electrochemically with a ca...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)00989-9
更新日期：1995-12-01 00:00:00
abstract：:The purpose of the present study is to examine the effects of mental fatigue and motivation on neural network dynamics activated during task switching. Mental fatigue was induced by 2 h of continuous performance; after which subjects were motivated by using social comparison and monetary reward as motivating factors t...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.03.015
更新日期：2009-05-13 00:00:00
abstract：:Immunohistochemical staining with mouse monoclonal antibody R24 recognizing the ganglioside GD3 was used to study the distribution of GD3 in the human brain. Positive staining was primarily found in the surrounding neuropil of many neuronal groups in the brainstem and spinal cord, cerebellum, retina and dentate gyrus ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90642-5
更新日期：1984-12-17 00:00:00
abstract：:Flexion movements induced by cortical stimulation and the associated postural adjustments in bilaterally pyramidotomised cats have been studied by means of an apparatus which measures separately the changes of force under each limb in the upright position of the animal. The results show: (1) The general motor behaviou...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(78)90586-3
更新日期：1978-06-23 00:00:00
abstract：:Applications of acetylcholine to hippocampal slices maintained in vitro resulted in slow depolarizations and simultaneous increases in membrane resistance (RN)in hippocampal pyramidal neurons. Increases in RN had both voltage dependent and voltage independent components. These effects were associated with increases in...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90089-5
更新日期：1981-04-27 00:00:00
abstract：:This ERP study explores the brain's response to the manipulation of motor compatibility in action-related language. In Experiment 1 participants read sentences in which a protagonist performed two different manual actions either simultaneously or consecutively (e.g. While/after cleaning the wound he unrolled the banda...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2013.06.020
更新日期：2013-08-14 00:00:00
abstract：:Chronic pain tends to be intractable, regardless of whether the etiology has improved or is persistent. This intractability may be due, in part, to conditioning factors, but studies of the underlying mechanism are limited. We predicted that the body might learn pain sensation during sustained pain. In the present stud...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.06.028
更新日期：2011-08-11 00:00:00
