Acetylcholine induced modulation of hippocampal pyramidal neurons.

abstract：:We found that local perfusion of COA-Cl (0.1, 0.4, or 1.0 mM) into the dorsal striatum of living mice produced a significant and dose-dependent increase in extracellular DA levels, with the highest dose of 1.0 mM COA-Cl producing an approximately 5-fold increase in DA. Consistent with in vivo findings, 0.1 and 0.2 mM ...

journal_title：Brain research

authors： Jamal M,Tsukamoto I,Takata M,Ito A,Tanaka N,Miki T,Takakura A,Ameno K,Kubota Y,Konishi R,Kinoshita H

更新日期：2019-03-01 00:00:00

abstract：:The mechanisms responsible for the rate of rise (RR) of cumulative depolarization induced by dorsal root stimulus trains were investigated with intracellular recordings from motoneurones of the rat isolated spinal cord. The NMDA receptor antagonists CPP or APV depressed the cumulative depolarization but not its RR whi...

journal_title：Brain research

authors： Baranauskas G,Nistri A

更新日期：1996-11-04 00:00:00

abstract：:The ultrastructural morphology and synaptic associations between enkephalin-containing neurons and sensory afferents was examined in the caudalis portion of rat spinal trigeminal complex, the region corresponding to Rexed's layer II of the dorsal horn. Specific antiserum to Met5-enkephalin was localized by the peroxid...

journal_title：Brain research

authors： Sumal KK,Pickel VM,Miller RJ,Reis DJ

更新日期：1982-09-30 00:00:00

abstract：:Ionic currents induced by glutamate, kainate, quisqualate, and N-methyl-D-aspartate (NMDA) in cultured septal neurons were analyzed by fluctuations analysis. The power spectrum (PWS) of NMDA current fluctuations always fitted a single Lorentzian. PWSs of the other agonists fitted the sum of two Lorentzians; however, t...

journal_title：Brain research

authors： Shingai R,Ebina Y

更新日期：1988-05-10 00:00:00

abstract：:A total of 183 nucleus basalis of Meynert (NBM) neurons were recorded in a monkey performing a delayed response task. Significant changes in discharge rate were detected in 74% of the NBM cells sampled with most responses occurring in the choice (64%) or the reward (67%) epochs of the task. Neuronal responses in the c...

journal_title：Brain research

authors： Richardson RT,DeLong MR

更新日期：1986-12-10 00:00:00

abstract：:Nitric oxide synthase (NOS) activity was examined in forebrain, cerebellum and optic lobes of adult domestic fowl, having a hereditary primary generalized convulsive disorder. NOS was approximately 2-fold higher in only the forebrain of adult epileptic fowl compared to non-epileptic (carrier) hatchmates. A significant...

journal_title：Brain research

authors： Sandirasegarane L,Mikler JR,Tuchek JM,Sulakhe PV

更新日期：1996-10-07 00:00:00

abstract：:The vascular changes in the hippocampus and neocortex during kainic acid-induced seizures were investigated in control rats and in rats with chronic, bilateral, cervical sympathectomy. Seizures were induced in unanesthetized, spontaneously breathing rats. The increase in blood flow in the hippocampus of the sympathect...

journal_title：Brain research

authors： Rigaud AS,Pinard E,Borredon J,Seylaz J

更新日期：1990-11-05 00:00:00

abstract：:Administration of either Tyr-D-Ala-Gly-MePhe-Gly(ol) (DAGO), a mu-opioid agonist, or nicotine into the VTA (A10) caused an increase in both dopamine (DA) and its metabolite levels in both the A10 region and DA nerve terminals in the nucleus accumbens of rats when assessed with dual probe brain dialysis. These findings...

journal_title：Brain research

authors： Yoshida M,Yokoo H,Tanaka T,Mizoguchi K,Emoto H,Ishii H,Tanaka M

更新日期：1993-10-08 00:00:00

abstract：:A hundred years after Lhx2 ortholog apterous was identified as a critical regulator of wing development in Drosophila, LIM-HD gene family members have proved to be versatile and powerful components of the molecular machinery that executes the blueprint of embryogenesis across vertebrate and invertebrate species. Here,...

journal_title：Brain research

authors： Chou SJ,Tole S

更新日期：2019-02-15 00:00:00

abstract：:The feedback effect of activity of area 21a on orientation maps of areas 17 and 18 was investigated in cats using intrinsic signal optical imaging. A spatial frequency-dependent decrease in response amplitude of orientation maps to grating stimuli was observed in areas 17 and 18 when area 21a was inactivated by local ...

journal_title：Brain research

authors： Huang L,Chen X,Shou T

更新日期：2004-02-20 00:00:00

abstract：:The extensive outgrowth from explanted goldfish retina in vitro stimulated by the axotomy of the optic nerve several days prior to the explantation, enables a more direct examination of the events which accompany optic nerve regeneration. Thus far neuritic outgrowth has been obtained in serum-containing medium. In the...

journal_title：Brain research

authors： Schwartz M,Mizrachi Y,Eshhar N

更新日期：1982-01-01 00:00:00

abstract：:Single unit activities of Y, X and W cells were recorded in the cat lateral geniculate nucleus to study how their responses to stationary light spots change with the cortical EEG. The shift from desynchronized to synchronized EEG drastically suppressed W cell activities, depressed both transient and sustained componen...

journal_title：Brain research

authors： Sawai H,Morigiwa K,Fukuda Y

更新日期：1988-07-12 00:00:00

abstract：:To identify whether altered expressions of voltage gated Ca(2+) channel (VGCC) are linked to inhibitory transmission abnormalities in the gerbil hippocampus, we investigated the effects of GABA receptor or somatostatin receptor (SST) antagonists/agonists on VGCC immunoreactivity in vivo. VGCC immunoreactivities in the...

journal_title：Brain research

authors： Kim DS,Kwak SE,Kim JE,Kim JS,Won MH,Kang TC

更新日期：2006-10-18 00:00:00

abstract：:Transplantation of mesenchymal stem cells (MSCs) prepared from adult bone marrow (BMSCs) has been reported to ameliorate functional deficits in several CNS diseases in experimental animal models. Bone marrow was enriched in MSCs by selecting for plastic-adherent cells that were grown to confluency in appropriate cultu...

journal_title：Brain research

authors： Kim S,Honmou O,Kato K,Nonaka T,Houkin K,Hamada H,Kocsis JD

更新日期：2006-12-06 00:00:00

abstract：:To identify the subtype of dopamine receptors critically involved in the rewarding effect of brain stimulation, four dopamine antagonists were intracranially injected in 25 rats. The importance of dopamine D1 receptors had been demonstrated previously by using SCH 23390, a highly selective D1 antagonist. Rats were imp...

journal_title：Brain research

authors： Nakajima S,Patterson RL

更新日期：1997-06-20 00:00:00

abstract：:Individuals are found to have better recall for self-referent information than other types of information. However, attribution research has shown that self-reference is highly correlated with emotional valence. The present study attempted to identify and separate the processing of self-reference and emotional valence...

journal_title：Brain research

authors： Watson LA,Dritschel B,Obonsawin MC,Jentzsch I

更新日期：2007-06-04 00:00:00

abstract：:Single cell suspensions of early postnatal mouse cerebellum adhere to substrate-bound culture supernatants of the teratocarcinoma cell line PF-HR9 and can be inhibited to adhere by antibodies to the neural cell adhesion molecules L1 and N-CAM. Adhesion can also be inhibited by the glycosaminoglycans heparin and hepara...

journal_title：Brain research

authors： Werz W,Schachner M

更新日期：1988-10-01 00:00:00

abstract：:Neonatal MK-801 treatment from postnatal day 8-19 leads to long-term effects on brain function, suggesting that exposure to this drug leads to the development of a brain with immature network properties. One aspect of this hypothesis, that the NMDA receptors preserve their immature state after the treatment, has been ...

journal_title：Brain research

authors： Gorter JA,Brady RJ

更新日期：1994-11-28 00:00:00

abstract：:C57BL/6J (B6) and DBA/2J (D2) mice have been characterized previously as seizure-resistant and seizure-sensitive, respectively, a distinction based primarily upon a differential response to the convulsant effects of various drugs. In the present study, electroconvulsive shock (ECS) was used to assess maximal electrosh...

journal_title：Brain research

authors： Ferraro TN,Golden GT,Snyder R,Laibinis M,Smith GG,Buono RJ,Berrettini WH

更新日期：1998-11-30 00:00:00

abstract：:Coated vesicles within dentate gyrus granule cell dendrites were found free in the cytoplasm and also attached to the smooth endoplasmic reticulum and plasmalemma. Coated vesicles began increasing in number 40-48 h following partial dendritic deafferentation. This increase continued up to 15-30 days postlesion, after ...

journal_title：Brain research

authors： McWilliams JR,Lynch G

更新日期：1981-04-27 00:00:00

abstract：:Extracellular recordings were carried out in the primary visual cortex of behaving macaque monkeys. Neurons were activated by moving a visual stimulus across their receptive fields during periods of steady fixation and by moving their receptive fields (by visual tracking) across a motionless visual stimulus, taking ca...

journal_title：Brain research

authors： Galletti C,Squatrito S,Battaglini PP,Grazia Maioli M

更新日期：1984-05-28 00:00:00

abstract：:Single unit extracellular recordings were obtained from cat lumbar spinal cord dorsal horn neurons activated by cutaneous inputs. The effect of electrical conditioning stimuli applied to the red nucleus (RN) was predominantly that of inhibition although in some cases excitation was seen. All the neurons that projected...

journal_title：Brain research

authors： Gray BG,Dostrovsky JO

更新日期：1984-10-08 00:00:00

abstract：:Vasopressinergic structures were examined within the magnocellular nuclei of the human basal forebrain. Vasopressinergic neurons were found in all parts of the diagonal band nucleus, and less frequently in the anteromedial subnucleus of the basal nucleus (Meynert). They belong to the group of large multipolar neurons,...

journal_title：Brain research

authors： Ulfig N,Braak E,Ohm TG,Pool CW

更新日期：1990-10-15 00:00:00

abstract：:The development of symptomatic epilepsy is a model of long-term plasticity changes in the central nervous system. The rat pilocarpine model of epilepsy was utilized to study persistent alterations in calcium/calmodulin-dependent kinase II (CaM kinase II) activity associated with epileptogenesis. CaM kinase II-dependen...

journal_title：Brain research

authors： Churn SB,Kochan LD,DeLorenzo RJ

更新日期：2000-09-01 00:00:00

abstract：:Few clinical or experimental studies have carried out systematic investigations of cutaneous and deep sensibility in areas with referred muscle pain. Therefore, no clear signs of increased or decreased psychophysical responses to various somatosensory stimuli are found in referred pain areas. In the present study, a t...

journal_title：Brain research

authors： Graven-Nielsen T,Arendt-Nielsen L,Svensson P,Jensen TS

更新日期：1997-01-02 00:00:00

abstract：:Gamma-hydroxybutyrate (GHB) has been shown to have therapeutical properties in various psychiatric disorders, especially in alcohol abuse, and to mimic different actions of ethanol at the cellular and system level. Using whole-cell patch-clamp recordings on brain slices of 21- to 25-day-old rats, the present study inv...

journal_title：Brain research

authors： Brancucci A,Berretta N,Mercuri NB,Francesconi W

更新日期：2004-01-30 00:00:00

abstract：:Brain edema is a serious consequence of hemispheric stroke and traumatic brain injury and contributes significantly to patient mortality. In the present study, we measured water contents in hippocampal slices as an in vitro model of edema formation. Excitotoxic conditions induced by N-methyl-D-aspartate (NMDA, 300 mic...

journal_title：Brain research

authors： Kumar V,Naik RS,Hillert M,Klein J

更新日期：2006-11-29 00:00:00

abstract：:Microtubule-associated protein 1B (MAP1B) is expressed at high levels during development of the nervous system and is localized primarily in neurons while specific phosphorylated isoforms of MAP1B are localized exclusively in growing axons. The levels of MAP1B are down regulated in most regions of the adult CNS, but r...

journal_title：Brain research

authors： Ma D,Chow S,Obrocka M,Connors T,Fischer I

更新日期：1999-03-27 00:00:00

abstract：:Our previous study reported that cathepsin L may contribute to the death of dopaminergic neurons in rodent model of Parkinson's disease (PD). In this study we detected the changes in the expression of lysosomal cathepsin L in cellular models of PD. In human neuroblastoma SH-SY5Y cells, treatment with 6-hydroxydopamine...

journal_title：Brain research

authors： Xiang B,Fei X,Zhuang W,Fang Y,Qin Z,Liang Z

更新日期：2011-04-28 00:00:00

abstract：:The objective was to determine if corticopetal basal forebrain neurons could co-synthesize different transmitters. Histochemical labeling of a molecular marker of connectivity (wheat germ agglutinin lectin-bound horseradish peroxidase [HRP]; axonal uptake and retrograde transport from neocortex) and immunohistochemica...

journal_title：Brain research

authors： Fisher RS,Levine MS

更新日期：1989-07-03 00:00:00