Fetal brain transplants induce recuperation of taste aversion learning.

Abstract:

:Rats showing disrupted taste aversion due to gustatory neocortex or amygdala lesions were transplanted into the lesioned area with homologous brain tissue obtained from 17-day-old fetuses. Comparisons of taste aversions scores before and after the graft, revealed that the grafted animals significantly recuperated taste aversions, whereas cortical lesioned animals without grafts did not. Surprisingly, however, amygdala-lesioned animals without graft presented spontaneous recovery. These results not only support the hypothesis that fetal brain transplants can restore cognitive functions, but also that there are some fundamental functional differences between the gustatory neocortex and the amygdala in the regulation of the processes involved in the acquisition and retention of taste aversion.

journal_name

Brain Res

journal_title

Brain research

authors

Bermúdez-Rattoni F,Fernández J,Sánchez MA,Aguilar-Roblero R,Drucker-Colín R

doi

10.1016/0006-8993(87)91507-1

subject

Has Abstract

pub_date

1987-07-21 00:00:00

pages

147-52

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(87)91507-1

journal_volume

416

pub_type

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