Blockade of dopamine D1 receptors by SCH 23390 antagonizes discriminative stimulus effects of pentazocine.

abstract：:This study compared the responsivity of alpha 2-adrenoceptors to agonists in normotensive (WKY) and genetically hypertensive (SH) rats. Clonidine produced a greater degree of analgesia in SH as compared to WKY rats. This analgesia was antagonized by yohimbine. Neither naphazoline nor 4-hydroxy-clonidine produced analg...

journal_title：Brain research

authors： Marwaha J

更新日期：1984-06-25 00:00:00

abstract：:The effects of 0.1 to 500 mM ethanol on NMDA-activated currents were studied in primary cultures of mouse cortical and hippocampal neurons. In whole-cell recordings the IC50S for inhibition of NMDA-activated currents by ethanol were 129 mM +/- 20 mM in hippocampal neurons and 126 +/- 18 mM in cortical neurons. In sing...

journal_title：Brain research

authors： Wright JM,Peoples RW,Weight FF

更新日期：1996-11-04 00:00:00

abstract：:Different mechanisms have been suggested to contribute to isoflurane-mediated neuroprotection. Previous studies have suggested that the protein Slit can abrogate neuronal death in mixed neuronal-glial cultures exposed to oxygen-glucose deprivation (OGD) and reperfusion (OGD/R). We hypothesized that isoflurane increase...

journal_title：Brain research

authors： Zhao XC,Zhang LM,Li Q,Tong DY,Fan LC,An P,Wu XY,Chen WM,Zhao P,Wang J

更新日期：2013-11-06 00:00:00

abstract：:The stimulated (40 Hz) release of enkephalin from the myenteric plexus can be modulated by multiple types of opiate receptor. The direction of the modulation is not fixed but is bimodal. Both an inhibition and an enhancement of evoked release is observed depending on the concentration of opioid agonist that is used. E...

journal_title：Brain research

authors： Xu H,Smolens I,Gintzler AR

更新日期：1989-12-11 00:00:00

abstract：:Central catecholaminergic nerves have been shown to participate in the integration of cardio-cardiac reflexes induced by coronary artery ligation in the rat. In this study we measured the turnover of dopamine, norepinephrine and epinephrine in microdissected brain regions to identify some of the specific neural loci i...

journal_title：Brain research

authors： Sole MJ,Hussain MN,Versteeg DH,de Kloet ER,Adams D,Lixfeld W

更新日期：1982-03-11 00:00:00

abstract：:Immunohistochemical studies with an antiserum raised against tyrosine hydroxylase have allowed us to demonstrate a dense dopaminergic innervation of the globus pallidus in the squirrel monkey. This innervation derived mostly from two fascicles that detached themselves from the major ascending dopaminergic bundle arisi...

journal_title：Brain research

authors： Parent A,Smith Y

更新日期：1987-11-24 00:00:00

abstract：:Studies related to brain oscillations pervade the neuroscience literature. Functional correlates of oscillations in the delta, theta, alpha, beta and gamma frequency windows are interpreted in several ways. However, only a small number of reports indicate the need for overall interpretations by integrating all type of...

journal_title：Brain research

authors： Başar E

更新日期：2008-10-15 00:00:00

abstract：:The effect of aging on the properties of N-methyl-D-aspartate (NMDA) receptors in the forebrain of female NMRI mice was investigated using the antagonist [3H]MK-801 as radioligand. Compared to young (3 months) mice, aged (20 months) mice showed changes of the properties of the NMDA receptor at three different levels: ...

journal_title：Brain research

authors： Cohen SA,Müller WE

更新日期：1992-07-03 00:00:00

abstract：:While axonal regeneration is more successful in peripheral nerve than in the central nervous system, it is by no means complete and research to enhance peripheral nerve regeneration is clinically important. Olfactory ensheathing cells (OECs) are known to enhance axonal regeneration and to produce myelin after transpla...

journal_title：Brain research

authors： Radtke C,Aizer AA,Agulian SK,Lankford KL,Vogt PM,Kocsis JD

更新日期：2009-02-13 00:00:00

abstract：:The levels of PLCgamma, a phospholipase C (PLC) isozyme, were higher in the cytosol fraction than in the membrane fraction in several control brain regions. The levels of PLCgamma were significantly elevated in the membrane, but not in the cytosolic fraction of the hippocampus of AD subjects. In the superior and middl...

journal_title：Brain research

authors： Zhang D,Dhillon H,Prasad MR,Markesbery WR

更新日期：1998-11-16 00:00:00

abstract：:Tetanization of commissural-CA1 input to the apical dendrites of the dorsal hippocampal CA1 area was found to produce a marked long-term potentiation of the field EPSP. Whereas by concurrent tetanization of the commissural pathway and medial septo-CA1 input, this potentiation was significantly reduced. Thus a negative...

journal_title：Brain research

authors： Xie XP

更新日期：1988-04-05 00:00:00

abstract：:Stereotaxic microinjections of the excitotoxin, ibotenic acid, were made into the striatum, hippocampus or cerebellum of the immature (7-day-old) rat. Two days later, pups were decapitated and the brains processed for light microscopic examination or neurochemical analyses. 10 micrograms ibotenate caused a complete lo...

journal_title：Brain research

authors： Steiner HX,McBean GJ,Köhler C,Roberts PJ,Schwarcz R

更新日期：1984-07-30 00:00:00

abstract：:Diabetes mellitus (DM) may lead to gastrointestinal motility disorders. Rodent models of DM indicate the presence of morpho-functional abnormalities of the enteric nervous system. Here, we evaluated whether experimental DM can cause changes in the excitatory cholinergic fibers, neuronal density, and voltage-gated sodi...

journal_title：Brain research

authors： Brasileiro AD,Garcia LP,de Carvalho da Silva S,Rocha LB,Pedrosa AL,Vieira AS,da Silva VJD,Rodrigues ARA

更新日期：2019-04-01 00:00:00

abstract：:Astrogliogenesis in the human fetal cerebellum was examined in 46 cerebella obtained from hysterotomy specimens ranging between 9 and 20 weeks of ovulation age. By correlating the results obtained by rapid Golgi and Golgi-Cox methods, the indirect immunofluorescence technique for glial fibrillary acidic protein, and e...

journal_title：Brain research

authors： Choi BH,Lapham LW

更新日期：1980-05-26 00:00:00

abstract：:Post-traumatic invasion of macrophages into the cochlear nerve of the rat and measurement of how their invasion was modified by the administration of methylprednisolone were investigated for the first time by using a reproducible and quantifiable experimental model of cochlear nerve injury. Two weeks after precise coc...

journal_title：Brain research

authors： Sekiya T,Tanaka M,Shimamura N,Suzuki S

更新日期：2001-06-29 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH)-like immunoreactivity was examined in the rat olfactory bulb by an immunohistochemical method using antiserum against the tripeptide TRH. TRH-immunoreactive neurons and neuronal processes were localized in both main and accessory olfactory bulb, including the glomerular layer, exter...

journal_title：Brain research

authors： Tsuruo Y,Hökfelt T,Visser TJ

更新日期：1988-04-26 00:00:00

abstract：:It was previously reported that chronic food restriction and maintenance of rats at 75-80% of initial body weight enhanced the reward-potentiating effect of D-amphetamine in the lateral hypothalamic self-stimulation (LHSS) paradigm. Moreover, the enhancement reversed in parallel with body weight recovery when ad libit...

journal_title：Brain research

authors： Hao J,Cabeza de Vaca S,Pan Y,Carr KD

更新日期：2006-05-04 00:00:00

abstract：:The regional distribution of FLFQPQRFamide binding sites on fresh unfixed cryostate sections from post mortem specimens of human spinal cord and lower medulla oblongata was studied by quantitative autoradiographic methods using [125I]YLFQPQRFamide as ligand. Samples were taken from five cases who had died with no hist...

journal_title：Brain research

authors： Allard M,Jordan D,Zajac JM,Ries C,Martin D,Monkouanga D,Kopp N,Simonnet G

更新日期：1994-01-07 00:00:00

abstract：:The postnatal development of acetylcholinesterase (AChE, EC 3.1.1.7) and NADH-diaphorase was examined in the caudate-putamen nucleus and substantia nigra of rats ranging from 3 to 90 days in age. From 3 to 15 days post partum islands of AChE and NADH-diaphorase activity were observed in the caudate-putamen nucleus. In...

journal_title：Brain research

authors： Butcher LL,Hodge GK

更新日期：1976-04-23 00:00:00

abstract：:The role of central delta-opioid receptors in the mediation of opioid reinforcement and endogenous reward processes was examined using a non-biased place-preference conditioning procedure. Intracerebroventricular (i.c.v.) administration of the selective delta-receptor agonist, [D-Pen2, D-Pen5]-enkephalin (DPDPE, 10.0-...

journal_title：Brain research

authors： Shippenberg TS,Bals-Kubik R,Herz A

更新日期：1987-12-15 00:00:00

abstract：:The lamprey brainstem contains a 'command system' which descends into the spinal cord to activate motor networks and initiate locomotion. In the present study, partial lesions were made in the rostral spinal cord in order to spare various tracts and determine which tracts carry the descending command signal to the spi...

journal_title：Brain research

authors： McClellan AD

更新日期：1988-08-09 00:00:00

abstract：:Axonal loss and degeneration in multiple sclerosis (MS) and experimental allergic encephalomyelitis (EAE) have been suggested by brain imaging, pathological and axonal transport studies. Further elucidation of the processes and mechanisms of axonal degeneration in demyelinating diseases is therefore of potential impor...

journal_title：Brain research

authors： Zhu B,Moore GR,Zwimpfer TJ,Kastrukoff LF,Dyer JK,Steeves JD,Paty DW,Cynader MS

更新日期：1999-04-10 00:00:00

abstract：:This study aimed at developing a dual setup of the photothrombotic ring stroke model with or without late spontaneous reperfusion in the region at risk and to explore the morphological consequences. The exposed crania of adult male Wistar rats were subjected to a ring-shaped laser-irradiation beam (o.d. 5.0 mm, 0.35 m...

journal_title：Brain research

authors： Hu X,Brännström T,Gu W,Wester P

更新日期：1999-12-04 00:00:00

abstract：:Experiments were done in cats to identify neurons in the paramedian reticular nucleus (PRN) sending collateral axons to the region of the intermediolateral nucleus (IML) at different levels of the thoracic cord by using lectin-conjugated horseradish peroxidase (HRP) and double-labeling fluorochrome histochemistry to r...

journal_title：Brain research

authors： Elisevich K,Caverson MM,Flumerfelt BA,Hrycyshyn AW,Ciriello J

更新日期：1987-04-07 00:00:00

abstract：:A neuron׳s response to a sound can be suppressed by the presentation of a preceding sound. It has been suggested that this suppression is a direct correlate of the psychophysical phenomenon of forward masking, however, forward suppression, as measured in the responses of the auditory nerve, was insufficient to account...

journal_title：Brain research

authors： Ingham NJ,Itatani N,Bleeck S,Winter IM

更新日期：2016-05-15 00:00:00

abstract：:Affective disorders and memory impairments precede the classical motor symptoms seen in Parkinson's disease (PD) and the currently approved antiparkinsonian agents do not alleviate the non-motor symptoms as well as the underlying dopaminergic neuron degeneration. On the other hand, there is increasing evidence that in...

journal_title：Brain research

authors： Castro AA,Wiemes BP,Matheus FC,Lapa FR,Viola GG,Santos AR,Tasca CI,Prediger RD

更新日期：2013-06-04 00:00:00

abstract：:The actions of sodium valproate (NaVP) were studied in the in vitro hippocampus using extracellular, intracellular and voltage-clamp recording techniques. In the CA1 region, concentrations of 30-200 microM NaVP reduced the amplitude but not the time course of post-tetanic potentiation (PTP) of dendritic field excitato...

journal_title：Brain research

authors： Griffith WH,Taylor L

更新日期：1988-11-22 00:00:00

abstract：:We examined the effects of chronic social stress and social rank on monamine concentrations in the prefrontal cortex (PFC) in adult male cynomolgus macaques (Macaca fascicularis). Seventy-five animals were housed in five-member social groups for 28 months and were exposed to three experimental conditions. A 'no-stress...

journal_title：Brain research

authors： Fontenot MB,Kaplan JR,Manuck SB,Arango V,Mann JJ

更新日期：1995-12-24 00:00:00

abstract：:In the rat, calbindin-like immunoreactivity was observed at both the light and electron microscopic levels within the chemoreceptor neurons of the vomeronasal organ (VNO) and both intragemmal cells and associated nerve fibers of the circumvallate taste buds. All VNO neurons were immunoreactive. Only a subset of intrag...

journal_title：Brain research

authors： Johnson EW,Eller PM,Jafek BW,Norman AW

更新日期：1992-02-14 00:00:00

abstract：:The purpose of this work was to characterize the gap junctions between cultured glomus cells of the rat carotid body and to assess the effects of acidity and accompanying changes in [Ca(2+)](i) on electric coupling. Dual voltage clamping of coupled glomus cells showed a mean macrojunctional conductance (G(j)) of 1.16 ...

journal_title：Brain research

authors： Abudara V,Jiang RG,Eyzaguirre C

更新日期：2001-10-19 00:00:00