Abstract：
:To determine the involvement of vasoactive intestinal polypeptide (VIP) in the development of kindling in rats, VIP or antibody to VIP (anti-VIP) was injected into the third ventricle after the daily stimulation of the basolateral amygdala. The number of stimulations required to reach full amygdaloid kindling was significantly smaller in rats treated with VIP than rats treated with saline, whereas it increased significantly in rats treated with anti-VIP compared to that in the rats treated with either saline or normal rabbit serum. The results suggest that VIP participates in the development of amygdaloid kindling as a facilitatory factor.
journal_name
Brain Resjournal_title
Brain researchauthors
Funabashi T,Hiruma H,Arita J,Kimura Fdoi
10.1016/0006-8993(91)91082-csubject
Has Abstractpub_date
1991-02-08 00:00:00pages
110-4issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(91)91082-Cjournal_volume
541pub_type
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