Abstract:
:Tetanic stimulation at 50 Hz elicited long-term potentiation (LTP) in the hippocampal CA1 region of 28-day-old control animals. In contrast, no significant potentiation was seen following the same tetanus in animals chronically exposed to 1000 ppm of lead acetate during development. Gender differences were observed in animals exposed to 500 ppm of lead. In females, LTP was significantly attenuated, while in males the LTP was identical to that of controls.
journal_name
Brain Resjournal_title
Brain researchauthors
Zaiser AE,Miletic Vdoi
10.1016/s0006-8993(00)02657-3subject
Has Abstractpub_date
2000-09-08 00:00:00pages
201-4issue
1-2eissn
0006-8993issn
1872-6240pii
S0006-8993(00)02657-3journal_volume
876pub_type
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