Abstract：
:Methylazoxymethanol acetate (MAM)-induced cortical hypoplasia resulted in a 2-fold increase in the concentration of norepinephrine and its metabolite, 3-methoxyl-4-hydroxyphenylglycol sulfate, and a 26% decrease in the Bmax for the beta-receptor ligand, [3H]dihydroalprenolol (DHA) in the rat cortex. Chronic treatment with desmethylimipramine did not further decrease DHA-labeled sites although prior lesion of the noradrenergic terminals with 6-hydroxydopamine markedly increased the number in the MAM-lesioned cortex.
journal_name
Brain Resjournal_title
Brain researchauthors
Beaulieu M,Coyle JTdoi
10.1016/0165-3806(82)90195-xsubject
Has Abstractpub_date
1982-08-01 00:00:00pages
491-4issue
4eissn
0006-8993issn
1872-6240journal_volume
256pub_type
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