Localization of cholinergic muscarinic receptors in rat brain by light microscopic radioautography.

Abstract:

:Injection of a potent, cholinergic muscarinic antagonist, [3H]3-quinuclidinyl benzilate ([3H]QNB), results in a localization of the drug to muscarinic receptors in rat brain. The distribution of these drug receptors was examined in various brain regions previously thought to contain cholinergic neurons. They were localized to dendritic regions in the hippocampus, corpus striatum, nucleus accumbens and cerebral cortex. Particularly in the hippocampus, the receptor distribution may correspond to that for cholinergic nerve terminals.

journal_name

Brain Res

journal_title

Brain research

authors

Kuhar M,Yamamura HI

doi

10.1016/0006-8993(76)90399-1

subject

Has Abstract

pub_date

1976-07-09 00:00:00

pages

229-43

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(76)90399-1

journal_volume

110

pub_type

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