CNTF potentiates peripheral nerve regeneration.

abstract：:The discontinuous terminal distributions of thalamo- and nigrostriatal axons were examined in adjacent tissue sections from single cat brains by combined anterograde labeling with tritiated proline autoradiography and wheat germ-horseradish peroxidase histochemistry. Injection of one tracer into the centromedian-paraf...

journal_title：Brain research

authors： Beckstead RM

更新日期：1985-05-27 00:00:00

abstract：:Concentrations of monoamines and metabolites and uric acid were measured in sequential 15-min microdialysis samples taken from the area of the supraoptic nucleus (SON) in 9 urethane-anaesthetized rats. A decrease in blood pressure of 40 mm Hg was induced by withdrawing 3-4 ml of blood from an indwelling jugular cathet...

journal_title：Brain research

authors： Kendrick KM,Leng G

更新日期：1988-02-09 00:00:00

abstract：:Nerve growth factor (NGF) transported intraaxonally from the adrenergic nerve terminals in the iris to the cell bodies in the superior cervical ganglion resulted in an increase in the activity of the enzyme ornithine decarboxylase in the ganglion. This occurred in both six-day-old and adult rats with the relative effe...

journal_title：Brain research

authors： Hendry IA,Bonyhady R

更新日期：1980-10-27 00:00:00

abstract：:Lateral ventricular injection of antibodies to dynorphin A(1-13) was previously shown to elevate lateral hypothalamic stimulation frequency threshold for eliciting feeding behavior. The antibodies utilized in that study cross-react completely with dynorphin A(1-17) and, to a lesser extent, dynorphin A(1-8). In the pre...

journal_title：Brain research

authors： Carr KD,Bak TH

更新日期：1990-01-22 00:00:00

abstract：:Correlative light and electron microscopic immunohistochemical methods were adapted for a descriptive analysis of the normal time course and pattern of expression and intraneuronal localization of the enzyme glutamic acid decarboxylase (GAD) in the neostriatum (Ns) of fetal, postnatal and adult cats. The differentiati...

journal_title：Brain research

authors： Fisher RS,Levine MS,Adinolfi AM,Hull CD,Buchwald NA

更新日期：1987-06-01 00:00:00

abstract：:The generation of oscillatory activity may be crucial to brain function. The coordination of individual neurons into rhythmic and coherently active populations is thought to result from interactions between excitatory and inhibitory cells mediated by local feedback connections. By using extracellular recording wires a...

journal_title：Brain research

authors： Ahrens KF,Freeman WJ

更新日期：2001-08-24 00:00:00

abstract：:Cytochrome P45011B1 (11 beta-hydroxylase) was detected in the brain of male rats by in situ hybridization methods. Normal Sprague-Dawley rats were compared to the transgenic strain TGR(mRen2)27, characterized by the expression of the murine Ren-2d renin gene and the development of severe hypertension. Specific ribopro...

journal_title：Brain research

authors： Erdmann B,Gerst H,Lippoldt A,Bülow H,Ganten D,Fuxe K,Bernhardt R

更新日期：1996-09-09 00:00:00

abstract：:Surgical microscopy and electrophysiological techniques were used to standardize the nomenclature for the pudendal nerve and sacral plexus according to their somatic axonal composition in the male rat. We conclude that the pudendal nerve is the segment running from the L6-S1 trunk to the sacral plexus, carrying effere...

journal_title：Brain research

authors： Pacheco P,Camacho MA,García LI,Hernández ME,Carrillo P,Manzo J

更新日期：1997-07-25 00:00:00

abstract：:In the present study, we report the localization of the Rev-ErbA alpha and beta nuclear orphan receptors, two closely related members of the nuclear hormone receptor superfamily, in the brain. Both Rev-ErbA variant mRNAs were highly expressed in the olfactory bulb, the hippocampus, and in the granular cells of the cer...

journal_title：Brain research

authors： Kainu T,Enmark E,Gustafsson JA,Pelto-Huikko MP

更新日期：1996-12-16 00:00:00

abstract：:Extended incubation of hippocampus slices in the presence of fatty acid-free bovine serum albumin (FAF-BSA) strongly enhanced the release of D-[3H]aspartate and [14C]GABA induced by veratridine. Saturation of the FAF-BSA with oleic acid abolished the enhancing effect. Spontaneous release and K+-induced release were no...

journal_title：Brain research

authors： Minc-Golomb D,Eimerl S,Levy Y,Schramm M

更新日期：1988-08-09 00:00:00

abstract：:Influence of dopamine agonists, methamphetamine (MAT, 1 mg/kg, i.p.) and apomorphine (APO, 1 mg/kg, i.p.), on the effects of amygdaloid lesions on thresholds for the defensive attack behavior elicited by electrical stimulation of the ventromedial hypothalamic nucleus was studied in cats. The thresholds were measured i...

journal_title：Brain research

authors： Maeda H,Maki S

更新日期：1986-01-15 00:00:00

abstract：:To investigate the reversibility of neuronal functions during deep and mild hypothermia, we have examined changes in membrane properties of pyramidal neurons of the CA3 region of hippocampal slices during cooling and rewarming (8 approximately 37 degrees C) of the perfusion medium. Hypothermia reduced the excitatory p...

journal_title：Brain research

authors： Aihara H,Okada Y,Tamaki N

更新日期：2001-03-02 00:00:00

abstract：:Methionine (Met) enkephalin is detectable in rat hypothalamic and neurointermediate lobe (NIL) tissue extracts using a specific radioimmunoassay. Reversed-phase HPLC revealed that only the pentapeptide form was present in the extracts. Total amounts of Met-enkephalin in extracts containing the median eminence (ME), su...

journal_title：Brain research

authors： Jessop D,Sidhu R,Lightman SL

更新日期：1990-05-14 00:00:00

abstract：:Bilateral removal of the cortical visual area in newborn cats produces degeneration of retinal ganglion cells. Measurements of over 4,000 cells and calculation of neuron densities from sample areas of retina in the adult show that the medium sized cell population in peripheral retina is reduced by 68%, whereas the pop...

journal_title：Brain research

authors： Pearson HE,Labar DR,Payne BR,Cornwell P,Aggarwal N

更新日期：1981-05-18 00:00:00

abstract：:We tested the hypothesis that intravenous infusion of human marrow stromal cells (hMSC) with a nitric oxide donor, (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl) aminio] diazen-1-ium-1,2-diolate (DETA/NONOate), enhances angiogenesis, neurogenesis and neurological functional recovery after stroke in rats compared to indivi...

journal_title：Brain research

authors： Chen J,Li Y,Zhang R,Katakowski M,Gautam SC,Xu Y,Lu M,Zhang Z,Chopp M

更新日期：2004-04-16 00:00:00

abstract：:Avian circadian rhythms are regulated by a multiple oscillatory system consisting of the pineal, the suprachiasmatic nucleus (SCN) and the eye. In the present study, ontogeny of circadian clock in the pineal and the SCN of chick embryo was examined using Per2 expression as a marker. A daily rhythmicity of Per2 express...

journal_title：Brain research

authors： Okabayashi N,Yasuo S,Watanabe M,Namikawa T,Ebihara S,Yoshimura T

更新日期：2003-11-14 00:00:00

abstract：:Binge-like ethanol treatment of septal neurons blunts GABAAR-mediated miniature postsynaptic currents (mPSCs), suggesting it arrests synaptic development. Ethanol may disrupt postsynaptic maturation by blunting feedback signaling through immature GABAARs. Here, the impact of ethanol on the sensitivity of mPSCs to zolp...

journal_title：Brain research

authors： DuBois DW,Trzeciakowski JP,Parrish AR,Frye GD

更新日期：2006-05-17 00:00:00

abstract：:Endogenous hyperprolactinaemia was induced in intact male rats by transplantation of pituitaries under the kidney capsule. Five days later the utilization of noradrenaline (NA) and dopamine (DA) in individual brain nuclei and changes of plasma prolaction (PRL) were measured. Inhibition of catecholamine synthesis by al...

journal_title：Brain research

authors： Kovács GL,Drago F,Acsai L,Tihanyi A,Scapagnini U,Telegdy G

更新日期：1984-12-17 00:00:00

abstract：:Regional cerebral blood flow (RCBF) and local cerebral glucose utilization (LCGU) were studied in normal, awake newborn beagle puppies using quantitative autoradiography. A highly significant linear relationship between RCBF and LCGU was present for all brain structures. Special attention was directed to the subependy...

journal_title：Brain research

authors： Pasternak JF,Groothuis DR

更新日期：1984-05-14 00:00:00

abstract：:Traumatic injury to the peripheral and central nervous systems very often causes axotomy, where an axon loses connections with its target resulting in loss of function. The axon segments distal to the injury site lose connection with the cell body and degenerate. Axotomized neurons in the periphery can spontaneously m...

journal_title：Brain research

authors： Smith TP,Sahoo PK,Kar AN,Twiss JL

更新日期：2020-08-01 00:00:00

abstract：:After glucocorticoid stimulation, glucocorticoid receptors (GRs) are translocated to the nucleus to modulate transcription of glucocorticoid target genes. The subcellular distribution and trafficking of GR in cultured cells has been studied quite intensively using several techniques. However, the intracellular localiz...

journal_title：Brain research

authors： Sarabdjitsingh RA,Meijer OC,de Kloet ER

更新日期：2010-05-17 00:00:00

abstract：:Clusters of carotid body (glomus) cells cultured from a few days to 3 weeks, maintained their morphological characteristics during this period. The resting potential (Em) and input resistance (Ro) did not change for 2 weeks but both declined afterwards. The intracellular pH (pHi) of glomus cells, measured with glass m...

journal_title：Brain research

authors： He SF,Wei JY,Eyzaguirre C

更新日期：1991-05-03 00:00:00

abstract：:In synaptosomal preparations from rat cerebral cortex, ouabain-sensitive Rb+ uptake was stimulated by ethanol (20-80 mM). Based on differential sensitivity to ouabain, 80% of this Na+,K(+)-ATPase activity represented activity of the alpha 1 isozyme while 20% was due to the alpha 2 and/or alpha 3 isozymes (alpha 2/ alp...

journal_title：Brain research

authors： Foley TD,Rhoads DE

更新日期：1994-08-08 00:00:00

abstract：:The prostacyclin (PGI2) formation in cerebral vessels, as reflected by the difference in concentration of internal carotid arterial and internal jugular venous radioimmunoassayed 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha), was determined under normocapnic and hypercapnic conditions in 5 patients with mild cereb...

journal_title：Brain research

authors： Uyama O,Nagatsuka K,Fukunaga R,Kusunoki M,Takano T,Yoneda S,Kimura K,Abe H

更新日期：1983-01-24 00:00:00

abstract：:Electroconvulsive stimulation (ECS), the experimental analogue of electroconvulsive therapy (ECT), has been shown to produce both functional and structural effects in the hippocampal formation in infrahuman species. These changes may relate to the antidepressant and cognitive effects of ECT observed in patients treate...

journal_title：Brain research

authors： Lamont SR,Stanwell BJ,Hill R,Reid IC,Stewart CA

更新日期：2005-08-16 00:00:00

abstract：:To investigate whether differences in vulnerability to free radicals might underlie differences among striatal neurons in their vulnerability to neurodegenerative processes such as occur in ischemia and Huntington's disease, we have analyzed the localization of superoxide free radical scavengers in different striatal ...

journal_title：Brain research

authors： Medina L,Figueredo-Cardenas G,Reiner A

更新日期：1996-02-05 00:00:00

abstract：:Small reductions in temperature have been shown to improve neurologic recovery after ischemia. We have examined the effect of temperature on biochemical and physiological changes during hypoxia using rat hippocampal slices as a model system. The postsynaptic population spike recorded from the CA1 pyramidal cell region...

journal_title：Brain research

authors： Amorim P,Cottrell JE,Kass IS

更新日期：1999-10-09 00:00:00

abstract：:Perinatal exposure to environmental tobacco smoke (ETS) has adverse effects on neurobehavioral development. In the current study, rats were exposed to ETS during gestation, during the early neonatal period, or both. Brains and hearts were examined for alterations in adenylyl cyclase (AC) activity and for changes in be...

journal_title：Brain research

authors： Slotkin TA,Pinkerton KE,Garofolo MC,Auman JT,McCook EC,Seidler FJ

更新日期：2001-04-13 00:00:00

abstract：:During a recent study of the effects of photoreceptor degeneration on Muller cells, we observed that unlike glia from normal adult retinas, glia from degenerating rat retinas could be cultured and maintained in vitro for several weeks. Using a variety of cell type specific antisera, we show that at least 70% of cells ...

journal_title：Brain research

authors： Sarthy PV

更新日期：1985-06-24 00:00:00

abstract：:Mammalian vestibular type I hair cells (VIHCs) are innervated by an afferent synaptic calyx which contains vesicles and is immunoreactive for GABA. We describe here the effects of GABA on electrophysiological properties and on cytosolic free-calcium levels ([Ca2+]i) of VIHCs isolated from guinea-pig ampullae. Whole-ce...

journal_title：Brain research

authors： Lapeyre PN,Kolston PJ,Ashmore JF

更新日期：1993-04-23 00:00:00