Abstract：
:Avian circadian rhythms are regulated by a multiple oscillatory system consisting of the pineal, the suprachiasmatic nucleus (SCN) and the eye. In the present study, ontogeny of circadian clock in the pineal and the SCN of chick embryo was examined using Per2 expression as a marker. A daily rhythmicity of Per2 expression was first detectable at embryonic day (ED) 18 in the pineal and at ED 16 in the SCN under light-dark (LD) cycles. The amplitude of the rhythmicity increased during the development. In contrast, little expression was observed during the development in constant darkness. These results suggest that although circadian clock matures by the end of the embryonic life in chicken, LD cycles are required for the expression of the Per2.
journal_name
Brain Resjournal_title
Brain researchauthors
Okabayashi N,Yasuo S,Watanabe M,Namikawa T,Ebihara S,Yoshimura Tdoi
10.1016/s0006-8993(03)03531-5subject
Has Abstractpub_date
2003-11-14 00:00:00pages
231-4issue
1-2eissn
0006-8993issn
1872-6240pii
S0006899303035315journal_volume
990pub_type
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