Fluoro-Jade B staining as useful tool to identify activated microglia and astrocytes in a mouse transgenic model of Alzheimer's disease.

abstract：:Cells in layers II-III or VI were activated by microdrop application of acetylcholine (ACh), while monitoring the intracellular response of layer V pyramidal cells. This enabled the tracing of functional connections between the cells of layers II-III or VI with those of layer V. ACh activation of layer II-III or VI ce...

journal_title：Brain research

authors： Kenan-Vaknin G,Malach R,Segal M

更新日期：1992-03-06 00:00:00

abstract：:Training can induce significant changes in brain functioning and behavioral performance. One consequence of training is changing the pattern of brain activation. Abacus training is of interest because abacus experts gain the ability to handle digits with unusual speed and accuracy. However, the neural correlates of nu...

journal_title：Brain research

authors： Li Y,Hu Y,Zhao M,Wang Y,Huang J,Chen F

更新日期：2013-11-20 00:00:00

abstract：:Thyroid hormone effects on brain somatostatin-like immunoreactivity (SRIF-LI) were studied in an in vitro model system. Serum was removed from the nutrient culture medium of fetal day-18 rat cerebral cortex cells maintained in primary, long-term, dispersed monolayer culture. Chronic administration of either T3 or T4 i...

journal_title：Brain research

authors： Peterfreund RA,Sawchenko PE,Vale W

更新日期：1985-03-04 00:00:00

abstract：:Explicit memory is widely assumed to reflect the conscious processes of recollection and familiarity. However, familiarity has been hypothesized to be supported by nonconscious processing. In the present functional magnetic resonance imaging (fMRI) experiment, we assessed whether familiarity is mediated by some of the...

journal_title：Brain research

authors： Thakral PP,Kensinger EA,Slotnick SD

更新日期：2016-02-01 00:00:00

abstract：:Deferoxamine (DFO) has shown therapeutic promise for the treatment of Parkinson׳s disease (PD) as it has reduced both behavioral and biochemical deficits when injected into the brain of rodent models of PD. Intranasally administered DFO targets the brain directly but non-invasively and has been effective in animal mod...

journal_title：Brain research

authors： Fine JM,Forsberg AC,Renner DB,Faltesek KA,Mohan KG,Wong JC,Arneson LC,Crow JM,Frey WH 2nd,Hanson LR

更新日期：2014-07-29 00:00:00

abstract：:Numerous studies with PC12 cells have suggested that the mitogen-activated protein (MAP) kinase pathway might play a major role in the neuronal differentiation that is induced by nerve growth factor (NGF). Cells of the PC12D subline extend neurites within several hours in response to NGF in the presence of inhibitors ...

journal_title：Brain research

authors： Sano M,Kitajima S

更新日期：1998-03-02 00:00:00

abstract：:The postnatal maturation of the medial preoptic area (MPOA) of male and female rats was studied by means of light and electron microscopy. In Golgi-Kopsch preparations, bi- and multipolar cells were present at birth in both sexes; the perikarya of most of these cells, as seen with the electron microscope, exhibited an...

journal_title：Brain research

authors： Reier PJ,Cullen MJ,Froelich JS,Rothchild I

更新日期：1977-02-25 00:00:00

abstract：:Electrophysiological recordings in rat brain slices have been used to study the actions of adenosine on striatal neurons and striatal excitatory amino acid neurotransmission originating in the cortex or the thalamus. Adenosine had no effects on membrane properties of striatal neurons. Adenosine and the A1 agonist N6-C...

journal_title：Brain research

authors： Flagmeyer I,Haas HL,Stevens DR

更新日期：1997-12-05 00:00:00

abstract：:In anaesthetized cats, effects of iontophoretic application of angiotensin II were studied in the nuclei of the tractus solitarius. Specifically, its effects were tested on single respiratory neurones, having rhythmic activity related temporally with the phrenic nerve discharge, and on presumed reflex interneurones, w...

journal_title：Brain research

authors： Sessle BJ,Henry JL

更新日期：1987-03-24 00:00:00

abstract：:Evidence is provided that carbonic anhydrase-II is localized in the central nervous system to wide spread systems of oligodendrocytes and restricted astroglia populations, involving both fiber bundles and neuropil. It is suggested that CO2 formed in activated axons may, via carbonic anhydrase-II, give rise to protons ...

journal_title：Brain research

authors： Agnati LF,Tinner B,Staines WA,Väänänen K,Fuxe K

更新日期：1995-04-03 00:00:00

abstract：:Dissimilarity of the electroencephalogram (EEG) between the two hemispheres was characterized by cross-approximate entropy (C-ApEn), an information statistical parameter applicable to nonlinear, aperiodic signals. EEGs were recorded bipolarly with pairs of epidural electrodes in the left and right frontal cortices. Th...

journal_title：Brain research

authors： Hudetz AG

更新日期：2002-11-01 00:00:00

abstract：:Discharges of neurons in the midpontine dorsal tegmental field (DTF neurons) were recorded and analyzed during locomotion and were compared with those of reticulospinal neurons (RS neurons) located lateral to the DTF area. The conduction velocity of the descending axon of the DTF neurons was significantly smaller than...

journal_title：Brain research

authors： Kawahara K,Mori S,Tomiyama T,Kanaya T

更新日期：1985-08-26 00:00:00

abstract：:The aim of this study was to evaluate the effects of hypothermia on bilirubin-induced alterations in brain cell membrane function and energy metabolism in the developing brain. Thirty-seven newborn piglets were divided randomly into four groups: normothermic control (NC, n=9); hypothermic control (HC, n=7); normotherm...

journal_title：Brain research

authors： Park WS,Chang YS,Chung SH,Seo DW,Hong SH,Lee M

更新日期：2001-12-20 00:00:00

abstract：:We describe a method to produce frog olfactory epithelium with a population of developmentally synchronized receptor cells suitable for electrophysiological studies. The epithelium is ablated with ZnSO4 and allowed to regenerate for 10 days. Generation of new cells is then blocked by continuous treatment with hydroxyu...

journal_title：Brain research

authors： Lidow MS,Gesteland RC,Shipley MT,Kleene SJ

更新日期：1987-02-01 00:00:00

abstract：:Dysfunction in the hypothalamic GABAergic system has been implicated in panic syndrome in humans. Furthermore, several studies have implicated the hypothalamus in the elaboration of pain modulation. Panic-prone states are able to be experimentally induced in laboratory animals to study this phenomenon. The aim of the ...

journal_title：Brain research

authors： Freitas RL,Uribe-Mariño A,Castiblanco-Urbina MA,Elias-Filho DH,Coimbra NC

更新日期：2009-12-11 00:00:00

abstract：:Identifiable giant neurons of Aplysia explored intracellularly behave differently at the offset of an intracellular electroshock (IES) or after a synaptic 'tetanization', according to their functional type: neurons of the stable type depolarize and fire at the offset of the IES, anodal or cathodal, thus eliciting an a...

journal_title：Brain research

authors： Chalazonitis N,Boisson M,Rome-Talbot D,Chagneux R

更新日期：1982-09-30 00:00:00

abstract：:The lack of the glycine transporter 1 (GlyT1) leads to early postnatal death due to failure of respiratory network activity. Here we demonstrate a segregated expression of GlyT1 on different astroglial cell populations of the ventral respiratory group. In TgN(hGFAP-EGFP) mice a combined immunohistochemical and electro...

journal_title：Brain research

authors： Szoke K,Härtel K,Grass D,Hirrlinger PG,Hirrlinger J,Hülsmann S

更新日期：2006-11-13 00:00:00

abstract：:The herpes virus suis has been used as a tracer for the pathways in the central nervous system of the rat. The viruses have been inoculated in various peripheral structures innervated by the trigeminal nerve, namely in the cornea by instillation or scarification, in the anterior chamber of the eye by injection and als...

journal_title：Brain research

authors： Martin X,Dolivo M

更新日期：1983-08-29 00:00:00

abstract：:Freezing and escape responses induced by gradual increases in the intensity of the electrical current applied to dorsal regions of the periaqueductal gray (dPAG) cause a distinct pattern of Fos distribution in the brain. From these studies, it has been suggested that a pathway involving the dPAG itself, dorsomedial hy...

journal_title：Brain research

authors： Ferreira-Netto C,Borelli KG,Brandão ML

更新日期：2005-01-21 00:00:00

abstract：BACKGROUND:Toll-like receptor 4 (TLR4) is an important mediator of the innate immune response. It significantly contributes to neuroinflammation and may be involved in ischemic tolerance. It is unknown how cerebral ischemia in the cortex and postconditioning might affect inflammatory reactions in the hippocampus or whe...

journal_title：Brain research

authors： Feng R,Li S,Li F

更新日期：2011-04-12 00:00:00

abstract：:The effects of a wide range of doses of systemically administered cysteamine were studied on locomotor behavior, passive avoidance memory, cortical and cerebrospinal fluid somatostatin-like immunoactivity and cortical levels of dopamine and norepinephrine. High doses of cysteamine (200 and 250 mg/kg s.c.) led to susta...

journal_title：Brain research

authors： Haroutunian V,Mantin R,Campbell GA,Tsuboyama GK,Davis KL

更新日期：1987-02-17 00:00:00

abstract：:Following codepletion of endogenous serotonin (5-HT, greater than 90%) and thyrotropin-releasing hormone (TRH, 66%) by neonatal treatment with the serotonergic neurotoxin, 5,7-dihydroxytryptamine (DHT), a 33% (n = 12, P less than 0.01) increase in specific TRH receptor binding was observed in adult rat spinal cord (SC...

journal_title：Brain research

authors： Sharif NA,Towle AC,Burt DR,Mueller RA,Breese GR

更新日期：1989-02-20 00:00:00

abstract：:The locus coeruleus of the adult albino rat is a clearly delimited nucleus in Nissl-stained preparations. It is surrounded by an extensive, relatively neuron-free neuropil which is not stained in reduced silver and Luxol fast blue preparations. Most if not all locus coeruleus neurons contain the enzyme dopamine-beta-h...

journal_title：Brain research

authors： Swanson LW

更新日期：1976-06-25 00:00:00

abstract：:Severed medial giant axons in crayfish can be rejoined in vitro with polyethylene glycol (PEG) to produce axoplasmic continuity and through transmission of action potentials. Severed axon-like processes of a mammalian neuroblastoma/glioma cell line seem to be rejoined to the cell body using PEG in tissue culture. Our ...

journal_title：Brain research

authors： Bittner GD,Ballinger ML,Raymond MA

更新日期：1986-03-05 00:00:00

abstract：:Avian circadian rhythms are regulated by a multiple oscillatory system consisting of the pineal, the suprachiasmatic nucleus (SCN) and the eye. In the present study, ontogeny of circadian clock in the pineal and the SCN of chick embryo was examined using Per2 expression as a marker. A daily rhythmicity of Per2 express...

journal_title：Brain research

authors： Okabayashi N,Yasuo S,Watanabe M,Namikawa T,Ebihara S,Yoshimura T

更新日期：2003-11-14 00:00:00

abstract：:It is well known that locus coeruleus (LC) of the rat shows intense mu-opioid receptor-like immunoreactivity (MOR-LI). In the course of our study on the distribution of MOR-LI in the brain of the Japanese monkey (Macaca fuscata), however, no MOR-LI was found in the LC although the distribution pattern of MOR-LI in oth...

journal_title：Brain research

authors： Chen J,Koyama N,Kaneko T,Mizuno N

更新日期：1997-05-02 00:00:00

abstract：:Effects of nitric oxide on glutamate (Glu) release in long-term potentiation (LTP) were investigated by superfusion of conventional (P2) and large (P3) synaptosomes prepared from the rat hippocampus. Basal releasing rates of endogenous Glu from P2 and P3 fractions were 103.6 and 85.2 pmol/min/mg protein, respectively....

journal_title：Brain research

authors： Kamisaki Y,Maeda K,Ishimura M,Omura H,Moriwaki Y,Itoh T

更新日期：1994-04-25 00:00:00

abstract：:Endothelin (ET) is a small peptide that activates astrocyte proliferation, regulates proliferation and migration of embryonic neural precursor cells and stimulates glioblastoma growth. We found that in mouse brain, ET and its receptor B (ETRB) were highly expressed in the subependymal zone (SEZ), an adult neurogenic n...

journal_title：Brain research

authors： Castañeda MM,Cubilla MA,López-Vicchi MM,Suburo AM

更新日期：2010-03-19 00:00:00

abstract：:An immunoneutralization technique with specific antibodies was used to explore the role of endogenous neuropeptide Y (NPY) in the adrenocorticotropic hormone (ACTH) release after hypoglycemic stress in the dog. Dogs received injections of rabbit antihuman NPY gamma-globulin (anti-NPY) or normal gamma-globulin (NGG) in...

journal_title：Brain research

authors： Inui A,Inoue T,Nakajima M,Okita M,Sakatani N,Okimura Y,Chihara K,Baba S

更新日期：1990-03-05 00:00:00

abstract：:Subcutaneous injection of formalin produces a biphasic pain response: a transient early phase followed by a tonic late phase. It has recently been suggested that development of the late phase depends upon the presence of the early one. In support of this suggestion, we now demonstrate that blocking the early phase by ...

journal_title：Brain research

authors： Vaccarino AL,Marek P,Liebeskind JC

更新日期：1992-02-14 00:00:00