Angiotensin II excites neurones in cat solitary tract nuclei which are involved in respiration and related reflex activities.

abstract：:The relationship between carotid body chemoreceptor activity and flow was studied in preparations superfused in vitro. The carotid bodies were excised from pentobarbitone-anesthetized cats and superfused with modified Tyrode's solution, buffered with HEPES-NaOH to pH 7.41. The bath temperature was kept constant at 37....

journal_title：Brain research

authors： Alcayaga J,Iturriaga R,Zapata P

更新日期：1988-07-05 00:00:00

abstract：:Injury to the central or peripheral nervous systems leads to the loss of cognitive and/or sensorimotor capabilities that still lack an effective treatment. Although injury to the nervous system involves multiple and complex molecular factors, alteration to protein homeostasis is emerging as a relevant pathological mec...

journal_title：Brain research

authors： Valenzuela V,Oñate M,Hetz C,Court FA

更新日期：2016-10-01 00:00:00

abstract：:Distribution of somatostatin (SS) immunoreactivity was observed in the preoptic-anterior hypothalamus (PO-AH) of the female rat brain. Six specific rabbit antibodies A (SS-14), B (SS-28), C (SS-28 complete), D (SS 14 and SS-28 both), E (SS preprohormone) and F (GHRH) were used for immunostaining using Avidin-Biotin Co...

journal_title：Brain research

authors： Bhatnagar M

更新日期：2001-05-11 00:00:00

abstract：:The principal finding in this study is that the callosal projection to the occipital cortex in rats and mice follows a complex and highly reproducible pattern which has not previously been described in detail. In some regions, the callosal projection is associated with well defined cytoarchitectonic boundaries such as...

journal_title：Brain research

authors： Cusick CG,Lund RD

更新日期：1981-06-15 00:00:00

abstract：:Somatostatin-like immunoreactivity (Som-LI) and glycine high-affinity uptake have been characterized in the Rana pipiens retina. These labels are found in both the outer and inner plexiform layers (OPL and IPL), suggesting that interplexiform cells (IPCs) contain both Som and glycine in this retina. In double-label ex...

journal_title：Brain research

authors： Smiley JF,Basinger SF

更新日期：1989-08-21 00:00:00

abstract：:Nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) containing fibers and neurons within the hippocampal formation and entorhinal cortex of the new world monkey were determined using a direct histochemical procedure. Occasional intensely stained bipolar NADPH-d positive neurons were seen in the polymorphi...

journal_title：Brain research

authors： Mufson EJ,Brady DR,Carey RG

更新日期：1990-05-21 00:00:00

abstract：:Microglial cyclo-oxygenase (COX) expression is considered to be important in the pathogenesis of Alzheimer's disease (AD) and, therefore, constitutes a key target for therapeutic intervention. We investigated the influence of AD plaque associated factors on COX-1 and COX-2 expression and activity in adult human microg...

journal_title：Brain research

authors： Hoozemans JJ,Veerhuis R,Janssen I,van Elk EJ,Rozemuller AJ,Eikelenboom P

更新日期：2002-10-04 00:00:00

abstract：:The zebrafish, Danio rerio, has become an important model species for examining olfactory system structure and function, yet little is known about developmental changes in olfactory bulb morphology from embryo to adult. The present study examined both normal growth and the effects of deafferentation on the bulb from h...

journal_title：Brain research

authors： Poling KR,Brunjes PC

更新日期：2000-02-21 00:00:00

abstract：:The distribution of calretinin containing neurons examined by in situ hybridization mapping was compared with that obtained by immunocytochemistry in the brain of octopus. Results revealed a close correspondence between the two types of investigations. Western blot analysis disclosed a 29 kDa protein immunostained wit...

journal_title：Brain research

authors： Altobelli GG,Cimini V

更新日期：2007-02-09 00:00:00

abstract：:The primary olfactory cortex of mouse embryos varying in age from the 13th to the 15th day of gestation is investigated with the aid of several techniques: Nissl and Golgi preparations, autoradiography and electron microscopy. It is observed that the earliest cells to complete their migrations are diffusely scattered ...

journal_title：Brain research

authors： Derer P,Caviness VS Jr,Sidman RL

更新日期：1977-03-04 00:00:00

abstract：:Breathing oxygen at sufficiently elevated pressures can trigger epileptiform seizures. Therefore, we tested the hypothesis that pre-treatment with FDA-approved antiepileptic drugs could prevent seizure onset in hyperoxia at 5 atmospheres absolute. We selected drugs from two putative functional categories, Na+-channel ...

journal_title：Brain research

authors： Demchenko IT,Zhilyaev SY,Moskvin AN,Krivchenko AI,Piantadosi CA,Allen BW

更新日期：2017-02-15 00:00:00

abstract：:An animal model of self-sustaining status epilepticus (SSSE) induced in rats by brief intermittent perforant path stimulation (PPS) was examined with regard to the effects of two conventional antiepileptic drugs, diazepam and phenytoin. Thirty or sixty minutes PPS induced SSSE characterized by continuous behavioral an...

journal_title：Brain research

authors： Mazarati AM,Baldwin RA,Sankar R,Wasterlain CG

更新日期：1998-12-14 00:00:00

abstract：:Awake, intact monkeys were trained to perform discrete flexion or extension movements of the hand about the wrist in response to visual signals. The object of the movement was to align a cursor, coupled to a manipulandum, on a target line. Cursor and target lines are displayed on a video monitor placed in front of the...

journal_title：Brain research

authors： Murphy JT,Kwan HC,MacKay WA,Wong YC

更新日期：1982-03-25 00:00:00

abstract：:Alterations in protein phosphorylation may be important in the pathogenesis of Alzheimer's disease and recent observations suggest that a subset of protein kinase pathways may be selectively altered. Calcium/calmodulin-dependent protein kinase II CaM kinase II) is the most abundant protein kinase in the brain and is b...

journal_title：Brain research

authors： Simonian NA,Elvhage T,Czernik AJ,Greengard P,Hyman BT

更新日期：1994-09-19 00:00:00

abstract：:This study investigated the relationship between central cholinergic neurons and insulin secretion in bilateral adrenalectomized fed rats. Neostigmine (a cholinesterase inhibitor, 5 x 10(-8) mol) administered into the third cerebral ventricle produced significant increases in hepatic venous plasma insulin and glucose ...

journal_title：Brain research

authors： Gotoh M,Iguchi A,Yatomi A,Uemura K,Miura H,Futenma A,Kato K,Sakamoto N

更新日期：1989-07-24 00:00:00

abstract：:In scrapie infection, prion protein (PrPSc) is localized in areas where there is neurodegeneration and astrocytosis. It is thought that PrPSc is toxic to neurons and trophic for astrocytes. In our study, paraffin sections from scrapie infected (263K and 139H) and control hamsters were examined with histological and im...

journal_title：Brain research

authors： Ye X,Scallet AC,Kascsak RJ,Carp RI

更新日期：1998-11-02 00:00:00

abstract：:The activity of the septo-hippocampal and nucleus basalis-cortical cholinergic pathways was investigated by measuring changes in the extracellular acetylcholine levels in the hippocampus and parietal cortex, by means of transversal microdialysis, during the acquisition and recall of a positively reinforced operant beh...

journal_title：Brain research

authors： Orsetti M,Casamenti F,Pepeu G

更新日期：1996-06-10 00:00:00

abstract：:Systemic injection of kainic acid (KA) in adult rat elicits a pattern of neuronal pathology which exhibits several features of human temporal lobe epilepsy. KA-induced seizure activity is accompanied by the activation of the calcium-dependent protease calpain in limbic structures. In the present study, we evaluated th...

journal_title：Brain research

authors： Bi X,Chang V,Siman R,Tocco G,Baudry M

更新日期：1996-07-08 00:00:00

abstract：:Treatment of rat brain sections and of thalamic and striatal membranes with phosphatidylinositol phospholipase C (PIPLC), an enzyme known to hydrolyse only phosphatidylinositol and its derivatives, significantly alters the specific binding of mu- and delta-opioid ligands on their receptors. These results suggest that ...

journal_title：Brain research

authors： Trovero F,Glowinski J,Lévy M

更新日期：1990-12-24 00:00:00

abstract：:Albino rats received 10 s of sub-seizure electrical stimulation applied to the dentate gyrus granule cells immediately after acquisition of information on trial 1 of a 2-trial radial maze spatial memory task. Granule cell stimulation selectively reduced the probability of accessing information held in declarative memo...

journal_title：Brain research

authors： Collier TJ,Routtenberg A

更新日期：1984-09-24 00:00:00

abstract：:The production and localization of cell-associated forms of beta-amyloid precursor protein (APP) of Alzheimer's disease was investigated in primary cultures of mouse glial cells. In both oligodendrocytes and astrocytes, immunofluorescence staining with an antibody against the carboxy terminus of APP revealed an intens...

journal_title：Brain research

authors： Mizuguchi M,Ikeda K,Kim SU

更新日期：1992-07-03 00:00:00

abstract：:We examined the distribution of myelin antigens recognized by monoclonal antibodies (mAbs) 01 and 04 in the developing ventral white matter of the cervical spinal cord of the rat using immunogold-labeled ultrathin cryosections. From the beginning of myelination after birth to multilamellar myelin in adult animals, we ...

journal_title：Brain research

authors： Schiff R,Rosenbluth J

更新日期：1995-07-24 00:00:00

abstract：:Classical anatomical depictions of the cervical sympathetic trunk label it as a cholinergic preganglionic structure. We studied the cervical sympathetic trunk of the rat following daily injection for 5 weeks of guanethidine monosulphate, a regimen known to selectively destroy adrenergic neurons outside of the blood-br...

journal_title：Brain research

authors： Zochodne DW,Low PA,Dyck PJ

更新日期：1989-10-02 00:00:00

abstract：:Metabotropic glutamate receptors (mGluRs) are thought to mediate diverse processes in brain including synaptic plasticity and excitotoxicity. These receptors are often divided into three groups by their pharmacological profiles. [3H]Glutamate binding in the presence of compounds selective for ionotropic glutamate rece...

journal_title：Brain research

authors： Testa CM,Hollingsworth ZR,Shinozaki H,Penney JB Jr,Young AB

更新日期：1997-10-31 00:00:00

abstract：:The ontogenic development of neurophysin has not been investigated so far. To study this problem, electron microscopic immunohistochemistry was performed on ultrathin sections of the posterior pituitary of foetal and newborn rats. A concomitant appearance of secretory granules and neurophysin was first noted in the po...

journal_title：Brain research

authors： Leclerc R,Pelletier G

更新日期：1977-07-01 00:00:00

abstract：:In seven female alpha-chloralose-anesthetized cats, 52 lateral thalamic neurons were tested with noxious distension of the urinary bladder, the distal colon and the lower esophagus. In addition, the neurons were characterized with innocuous and noxious mechanical stimulation of the skin and deep structures. Of the 52 ...

journal_title：Brain research

authors： Horn AC,Vahle-Hinz C,Brüggemann J,Petersen M,Kniffki KD

更新日期：1999-12-18 00:00:00

abstract：:The subpallial region of the avian telencephalon contains neural systems whose functions are critical to the survival of individual vertebrates and their species. The subpallial neural structures can be grouped into five major functional systems, namely the dorsal somatomotor basal ganglia; ventral viscerolimbic basal...

journal_title：Brain research

authors： Kuenzel WJ,Medina L,Csillag A,Perkel DJ,Reiner A

更新日期：2011-11-18 00:00:00

abstract：:Calcium-binding proteins play a critical role in vertebrate sensory cells, and some of them have been detected in mechanosensory and chemosensory cells of bony and cartilaginous fishes. In this study immunohistochemistry and Western blot were used to investigate the occurrence and the distribution of S100 protein and ...

journal_title：Brain research

authors： Germanà A,Paruta S,Germanà GP,Ochoa-Erena FJ,Montalbano G,Cobo J,Vega JA

更新日期：2007-08-08 00:00:00

abstract：:Recent experimental data have shown that hyperbaric oxygen therapy (HBOT) was associated increased Bcl-2 expression at the injury site that correlated with reduced apoptosis. We hypothesized that HBOT mediated enhancement of Bcl-2 expression and increased intracellular oxygen bio-availability may both contribute to pr...

journal_title：Brain research

authors： Palzur E,Zaaroor M,Vlodavsky E,Milman F,Soustiel JF

更新日期：2008-07-24 00:00:00

abstract：:Measurements of extracellular Ca2+ and K+ activities [( Ca2+]o, [K+]o) in the superfused cat carotid body in vitro with triple-barrelled ion-selective electrodes have shown that hypoxia induced a decrease in [Ca2+]o of 0.035 +/- 0.17 mM (mean +/- S.D.; n = 17) and a biphasic change in [K+]o which consisted of an incre...

journal_title：Brain research

authors： Delpiano MA,Acker H

更新日期：1989-03-20 00:00:00