Abstract：
:In seven female alpha-chloralose-anesthetized cats, 52 lateral thalamic neurons were tested with noxious distension of the urinary bladder, the distal colon and the lower esophagus. In addition, the neurons were characterized with innocuous and noxious mechanical stimulation of the skin and deep structures. Of the 52 neurons tested, 32 (62%) were visceroceptive. Of these visceroceptive neurons, 20 (63%) were located in the periphery of the ventral posterolateral nucleus (VPLp), 10 (31%) in the adjacent posterior complex (PO), and two (6%) in the ventrolateral nucleus (VL). No differences were found with respect to location between neurons responsive or unresponsive to visceral stimulation. Ten neurons (31%) received input from more than one viscus and, therefore, showed viscerovisceral convergence. Excitatory or "inhibitory" responses were elicited by stimulation of the esophagus in 21 neurons, of the colon in 13, and of the urinary bladder in 11 neurons. No indications were found for a segregation of neurons responsive to a certain viscus and their location in VPLp or PO. Of 51 neurons, for which a somatic receptive field was determined, 44 (86%) exhibited low threshold type (LT), and seven (14%) wide dynamic range type (WDR) responses. The data indicate that there might exist a somatovisceral coregistration, because many neurons (69%) had homosegmental receptive fields, and bladder stimulation was the most successful stimulus. It is concluded that VPLp and the adjacent PO in the cat play a role in the perception and localization of painful events originating from thoracic and pelvic organs.
journal_name
Brain Resjournal_title
Brain researchauthors
Horn AC,Vahle-Hinz C,Brüggemann J,Petersen M,Kniffki KDdoi
10.1016/s0006-8993(99)02180-0subject
Has Abstractpub_date
1999-12-18 00:00:00pages
164-74issue
1-2eissn
0006-8993issn
1872-6240pii
S0006-8993(99)02180-0journal_volume
851pub_type
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