Abstract：
:Electrical stimulation of the cerebellar fastigial nucleus (FN) in spontaneously hypertensive (SHR), Wistar-Kyoto (WKY) and Fisher rats reduced, by approximately 50%, the infarctions produced by occlusion of the middle cerebral artery. Blockade of ATP-dependent potassium (K-ATP) channels with glibenclamide (i.c.v.) abolished salvage only in the SHR rat. While blockade of K-ATP channels failed to abolish salvage in WKY and Fisher rats, participation of potassium channels in neurogenic neuroprotection cannot be excluded.
journal_name
Brain Resjournal_title
Brain researchauthors
Golanov EV,Christensen JD,Reis DJdoi
10.1016/s0006-8993(99)01871-5subject
Has Abstractpub_date
1999-09-25 00:00:00pages
496-500issue
2eissn
0006-8993issn
1872-6240pii
S0006-8993(99)01871-5journal_volume
842pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Close to 20% of the patients infected with the AIDS virus develops neurological deficit; eventhough HIV does not invade neurons. Consistently with the neurological deficit, HIV(+) subjects show abnormalities in brainstem auditory and visual evoked potentials (BSAEP and VEP) and in sleep patterns. The HIV-derived glyco...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01572-3
更新日期：1999-07-31 00:00:00
abstract：:Receptor subunit composition is believed to play a major role in the synaptic trafficking of AMPA receptors (AMPARs), and thus in activity-dependent synaptic plasticity. To isolate a physiological role of GluA1-containing AMPARs in area CA3 of the hippocampus, pair recordings were performed in organotypic hippocampal ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.11.029
更新日期：2012-01-30 00:00:00
abstract：:Snake venom kappa-neurotoxins are selective antagonists of nicotinic acetylcholine responses in avian, murine and bovine neurons, and have been used as probes for functionally defined vertebrate neuronal nicotinic receptors. The actions of kappa-bungarotoxin, a kappa-neurotoxin, have now been examined at a central inv...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90494-5
更新日期：1988-08-16 00:00:00
abstract：:In a rat model of peripheral inflammation and hyperalgesia, dynorphin A(1-8)-like immunoreactive (DYN-LIr) spinal neurons were examined for contacts from calcitonin gene-related peptide-like immunoreactive (CGRP-LIr) varicosities using a double-label PAP method. Ipsilateral to the inflammation, CGRP-LIr varicosities c...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90213-2
更新日期：1988-12-13 00:00:00
abstract：:After transplantation of autologous sciatic nerve segments into the retina of adult hamsters for 1-2 months, retrograde labelling with horseradish peroxidase demonstrated a population of ganglion cells situated peripheral to the graft. If an additional lesion was placed between the insertion of the graft and the optic...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91203-5
更新日期：1986-07-02 00:00:00
abstract：:In order to better understand the neuroleptic-like effects of neurotensin in vivo, the effects of neurotensin in vitro on dopamine D2 and D1 agonist and antagonist binding sites were characterized in membranes from the neostriatum and the subcortical limbic area. Neurotensin increased the KD but not the Bmax value of ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90753-i
更新日期：1991-10-04 00:00:00
abstract：:The origin of neuronal perikarya which project to the external zone of the median eminence (the tuberoinfundibular neuronal system) was determined in the rat after injection or diffusion of wheat germ agglutinin (WGA) into the median eminence. The retrogradely transported lectin was detected in neurons using an immuno...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90334-1
更新日期：1982-08-05 00:00:00
abstract：:In situ hybridization (ISH) is an essential technique for mapping gene expression in the brain. Although many ISH protocols provide for quantitative analysis of individual mRNAs in different brain regions or across experimental conditions, this technique has lacked the necessary standardization for quantitative compar...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2003.11.069
更新日期：2004-03-12 00:00:00
abstract：:Three to five microliters of 50% HRP in saline was injected along a central axis into one of the 6 extraocular muscles in each of 18 adult pigeons. The brain was fixed and serially sectioned 16-20 h postinjection and the HRP reacted with tetramethylbenzidine (TMB). HRP-labeled proprioceptive neurons were located in th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90554-6
更新日期：1982-04-08 00:00:00
abstract：:(1) The possibility that water intake elicited by the administration of angiotensin-II to the preoptic region (POA), subfornical organ and anterior third ventricle is mediated by separate neural systems was investigated in 58 male Wistar rats using electrolytic lesion techniques. (2) Lesions of the midlateral hypothal...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(76)90189-x
更新日期：1976-05-28 00:00:00
abstract：:Acupuncture is widely used to relieve pain; however, the mechanism underlying electroacupuncture analgesia (EAA) during inflammatory pain is unclear. We investigated whether endogenous peripheral opioid receptors participated in EAA during hyperalgesia elicited by carrageenan-induced inflammation. Moreover, we investi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.08.014
更新日期：2010-10-08 00:00:00
abstract：:Deacetylation is a rapid clearance mechanism for ocular melatonin. We have studied the distribution of retinal melatonin deacetylase activity among vertebrate classes. Exogenous radiolabeled melatonin is metabolized by ocular tissue prepared from the amphibian Xenopus laevis, the reptile Anolis carolinensis, the teleo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90286-5
更新日期：1991-09-13 00:00:00
abstract：:The locus coeruleus was stimulated in 62 cats in order to investigate the effect on cephalic blood flow and cephalic vascular resistance. Flow was measured by electromagnetic flow probes applied to the common carotid artery. Stimulation over a range of frequencies (0.2-200 s-1) produced a frequency-dependent fall in c...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90236-6
更新日期：1983-11-14 00:00:00
abstract：:The neural representation of facial expression within the human visual system is not well defined. Using an adaptation paradigm, we examined aftereffects on expression perception produced by various stimuli. Adapting to a face, which was used to create morphs between two expressions, substantially biased expression pe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.09.104
更新日期：2007-01-05 00:00:00
abstract：:The present study aimed to determine the kinetics of L-3, 4-dihydroxyphenylalanine (L-DOPA) uptake in an immortalised cell line of rat capillary cerebral endothelial cells (clones RBE 4 and RBE 4B), to define the type of inhibition produced by L-5-hydroxytryptophan (L-5-HTP), 2-aminobicyclo(2,2,1)-heptane-2-carboxylic...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01387-6
更新日期：1999-05-22 00:00:00
abstract：:Abeta amyloidosis and tauopathy are characteristic changes in the brain of Alzheimer's disease. Although much evidence suggests that Abeta deposit is a critical initiation factor, the pathological pathway between Abeta amyloidosis and tau accumulation remains unclear. Tau accumulation was examined in the doubly transg...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.12.134
更新日期：2006-06-13 00:00:00
abstract：:Slow field potentials (SFP) lasting up to 5 s followed penicillin-induced bursts in CA3 of guinea pig hippocampal slices and accounted for most of the interburst interval. The longest lasting component of the SFP which was maximal in the distal apical dendritic region was usually absent in s. pyramidale. Potassium flu...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90138-7
更新日期：1987-02-10 00:00:00
abstract：:Previous studies have suggested that cardiovascular responses elicited by injection of glycine into the nucleus tractus solitarii (NTS) depend upon interactions between glycinergic and cholinergic neuronal elements in NTS. Release of acetylcholine in response to glycine is one such interaction that has been shown in s...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)91789-2
更新日期：1994-07-11 00:00:00
abstract：:We have previously identified a cell senescence-related, detergent-insoluble cytoplasmic protein referred to as terminin, and have presented the development-dependent modification of terminin polypeptides in rat brain. In the present study, we characterize biochemically and immunocytochemically terminin expression in ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)91679-9
更新日期：1994-05-02 00:00:00
abstract：:Previous studies have suggested that monosynaptic transmission between spinal primary afferent fibers and motoneurons is mediated by an excitatory amino acid, most likely glutamate or aspartate. No such comparable studies have been carried out in the trigeminal system. In an attempt to elucidate the neurotransmitter(s...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)91413-3
更新日期：1989-01-16 00:00:00
abstract：:Systemic endothelin-1 (ET-1) enhances the activity of subfornical organ (SFO) neurons with identified projections to the paraventricular nucleus of the hypothalamus (PVN). The present electrophysiological experiments were undertaken to examine the mechanisms through which systemic ET influences vasopressin secretion. ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91378-r
更新日期：1992-07-17 00:00:00
abstract：:In urodele amphibians, the hypothalamic neuropeptide arginine vasotocin and the adrenal steroid corticosterone interact to regulate reproductive behavior by actions in the brain. The present study investigated signal transduction pathways underlying acute effects of vasotocin and corticosterone, presumably mediated vi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.11.071
更新日期：2007-02-23 00:00:00
abstract：:A hypothalamic oxytocinergic-descending pathway that reaches the dorsal horn of the spinal cord has been well documented and recently related to states of pain and analgesia. In order to study the action of the neuropeptide oxytocin (OT) on pain-related responses, we compared dorsal horn neuronal responses to electric...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.03.020
更新日期：2005-05-31 00:00:00
abstract：:Williams Syndrome (WS) is a neurodevelopment disorder associated with a hemizygous deletion on chromosome 7. WS is characterized with mental retardation, severe visual-spatial deficits, relative language preservation, and excellent facial recognition. Distinctive auditory features include musical ability, heightened s...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.11.038
更新日期：2005-03-10 00:00:00
abstract：:Data reported up to now on neuron-glia relationships, show that neuron cell bodies and glial cells are separated by a narrow intercellular cleft which is considered as the microenvironment of the nervous system, and where neuron-glia exchange occurs. We present here evidence that neuron perikarya and ensheathing glial...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91394-0
更新日期：1985-02-04 00:00:00
abstract：:Cerebral vascular density is correlated with metabolic demands, which increase in highly active brain areas. External inputs are an essential requirement in the modeling of the visual cortex. Experience-mediated development is very active during the first postnatal month, when congruous blood supply is needed. We stud...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)02361-6
更新日期：2000-02-07 00:00:00
abstract：:While moderate calorie restriction (CR) in the absence of malnutrition has been consistently shown to have a systemic, beneficial effect against aging in several animals models, its effect on the brain microstructure in a non-human primate model remains to be studied using post-mortem histopathologic techniques. In th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2013.02.046
更新日期：2013-05-01 00:00:00
abstract：:The amount of myelin and its protein composition was studied in hypothyroid rats during the first 30 days after birth. Although the brain weight was 92% of that in the controls, the yield of myelin in hypothyroid animals was only 60% of that in controls. The protein and glycoprotein ocmposition of the isolated myelin ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(75)90764-7
更新日期：1975-02-14 00:00:00
abstract：:An autoradiographic determination of the time of origin of the lateral motor columns (LMC) of the chick embryo has been made. The first motor neurons of the brachial LMC are born at stage 15; the earliest birthdates of lumbar LMC neurons are at stage 17. At least 95% of the motor neurons of both brachial and lumbar co...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(77)90416-4
更新日期：1977-08-26 00:00:00
abstract：:Neural stem cells can be derived from the adult/embryonic nervous system as well as from more primitive embryonic stem cells but, because of the lack of specific markers, only their differentiated progeny can be characterized. We here report the presence of several endothelial and hematopoietic receptors (at protein a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)03291-7
更新日期：2002-01-25 00:00:00
