Abstract:
:Treatment of rat brain sections and of thalamic and striatal membranes with phosphatidylinositol phospholipase C (PIPLC), an enzyme known to hydrolyse only phosphatidylinositol and its derivatives, significantly alters the specific binding of mu- and delta-opioid ligands on their receptors. These results suggest that some opioid binding proteins are membrane-anchored by a glycosylphosphatidylinositol (GPI) linkage.
journal_name
Brain Resjournal_title
Brain researchauthors
Trovero F,Glowinski J,Lévy Mdoi
10.1016/0006-8993(90)90391-nsubject
Has Abstractpub_date
1990-12-24 00:00:00pages
381-5issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(90)90391-Njournal_volume
537pub_type
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