Abstract:
:Rabbits reared from birth in stroboscopic illumination have no experience of visual motion. In primary visual cortex of these animals there is a large reduction in the number of cells which are direction selective. This result, contrary to previous reports, shows that the rabbit visual system can be modified by early visual experience.
journal_name
Brain Resjournal_title
Brain researchauthors
Pearson HE,Berman N,Murphy EHdoi
10.1016/0165-3806(81)90099-7subject
Has Abstractpub_date
1981-01-01 00:00:00pages
127-31issue
1eissn
0006-8993issn
1872-6240journal_volume
227pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::Synapsin I is believed to be involved in regulating neurotransmitter release and in synapse formation. Its interactions with the actin filaments and synaptic vesicles are regulated by phosphorylation. Because exocytosis and synapsin I phosphorylation are a Ca(2+)-dependent process, it is possible that an ischemic insu...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2003.09.069
更新日期:2004-01-16 00:00:00
abstract::Increases in concentration of brain NO are proposed to initiate and mediate migraine headache. Triggered by focal depolarisation, spreading depression (SD) represents a suitable mechanism for eliciting widespread release of nitric oxide. The current study examines the effect of sumatriptan, a 5-HT(1B/1D) agonist and e...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02400-8
更新日期:2000-07-07 00:00:00
abstract::The Mesulam technique for horseradish peroxidase was used to study the subcortical afferent projections to a location in the hypothalamus that has been shown to control the complete cardiovascular (CV) response accompanying a specific emotional behavior. Major projections common to all baboons injected included the la...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90389-4
更新日期:1982-12-09 00:00:00
abstract::Glucose modulates substantia nigra (SN) dopamine (DA) neuronal activity and GABA axon terminal transmitter release by actions on an ATP-sensitive potassium channel (K(ATP)). Here, the effect of altering SN glucose levels on striatal DA release was assessed by placing microdialysis probes into both the SN and striatum ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02573-7
更新日期:2000-08-25 00:00:00
abstract::The effect of electrolytic lesion of the paraventricular nucleus of the hypothalamus (PVN) on yawning and penile erection induced by apomorphine, oxytocin and adrenocorticotropic hormone (ACTH1-24) was studied in male rats. In sham-operated rats, apomorphine (50 micrograms/kg s.c.), oxytocin (30 ng i.c.v.), and ACTH1-...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)91305-9
更新日期:1987-09-22 00:00:00
abstract::Recent researches suggest that autophagic degradation declines with age, and this leads to an accumulation of damage that contributes to age-related cellular dysfunction. Nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1) shows therapeutic potential for cerebral ischemia in young-adult animals. This study inve...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2019.146391
更新日期:2019-11-15 00:00:00
abstract::A special feature of the extracellular matrix in adult brains of various species is the concentration of certain components around different sub-populations of neurones, giving rise to net-like structures termed perineuronal nets. Recently, some of these components have been identified but the function of these nets h...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)01596-6
更新日期:1999-07-10 00:00:00
abstract::Artificial CSF containing 12mEq/1 of potassium (4 times normal concentration) was perfused over the surface of normal neocortex in 10 locally or barbiturate anesthetized cats. Extracellular potassium concentrations ([K+]OS) were measured as a function of time to 8 h and of depth to 3 mm. Analysis of the [K+]O versus d...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(76)90265-1
更新日期:1976-01-16 00:00:00
abstract::Docosahexaenoic acid (DHA), an omega-3 polyunsaturated fatty acid, is an essential component of membrane phosphatides and has been implicated in cognitive functions. Low levels of circulating or brain DHA are associated with various neurocognitive disorders including Alzheimer's disease (AD), while laboratory animals,...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.08.089
更新日期:2007-11-28 00:00:00
abstract::The putative neurotransmitter substance P was localized in the embryonic and neonatal mouse trigeminal nerve by indirect immunofluorescence. Central terminals in the nucleus caudalis gave a positive substance P-like immunofluorescence (SPLI) reaction of E13-E14. SPLI subsequently appeared in the peripheral mucous and ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(82)90147-x
更新日期:1982-07-01 00:00:00
abstract::To test the hypothesis that functional metabolic deficits observed following surgical brain injury are associated with changes in cognitive performance in rodents, we performed serial imaging studies in parallel with behavioral measures in control animals and in animals with surgical implants. Memory function was asse...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.01.134
更新日期:2007-05-04 00:00:00
abstract::The purpose of this study was to investigate the cannabinoid and opioid mediated regulation on the effects of central Delta(9)-tetrahydrocannabinol (Delta(9)-THC) administration on hypothalamus-pituitary-adrenal (HPA) axis activity in the male rat. Intracerebroventricular (i.c.v.) administration of delta(9)-THC (25, 5...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)01756-4
更新日期:1999-08-21 00:00:00
abstract::Recent experimental data have shown that hyperbaric oxygen therapy (HBOT) was associated increased Bcl-2 expression at the injury site that correlated with reduced apoptosis. We hypothesized that HBOT mediated enhancement of Bcl-2 expression and increased intracellular oxygen bio-availability may both contribute to pr...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2008.04.078
更新日期:2008-07-24 00:00:00
abstract::The central axon of a primary afferent neuron that responded to light mechanical stimulation of the lower premolar teeth in a fast adapting fashion was intra-axonally injected with horseradish peroxidase in the cat. The labeled terminals within the rostrodorsomedial (Vo.r) and dorsomedial (Vo.dm) parts of subnucleus o...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)91588-j
更新日期:1993-03-19 00:00:00
abstract::Axonal projections of ganglion cells to the superior colliculus (SC) and to the nucleus of the optic tract (NOT) were re-examined physiologically in the cat's retina. Taking care to minimize current spreads around the stimulating electrodes placed in the NOT or the SC, we reached a conclusion that a substantial propor...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91465-9
更新日期:1985-08-19 00:00:00
abstract::Extracellular ATP can influence cells via activation of P2X purinoceptors, the distribution of which can be altered in the central and peripheral nervous systems following injury or tissue damage. Here we have investigated the effect of a unilateral section of the cervical vagus nerve on the distribution of P2X(1), P2...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(03)02797-5
更新日期:2003-07-04 00:00:00
abstract::The weakly electric fish Apteronotus leptorhynchus produces electric organ discharges which are highly stable in waveform and frequency. Short-term modulations of these discharges, typically displayed during social interactions, are controlled by the prepacemaker nucleus (PPn). Neurons of this thalamic cell group inte...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(96)00818-9
更新日期:1996-11-11 00:00:00
abstract::Neural transplantation is a promising approach for treating neurodegenerative disease. Neural stem/progenitor cells (NPCs) are self-renewing and multipotent and thus are good candidates for donor cells when they have been clearly defined to differentiate into neurons. As neuronal differentiation follows cell cycle exi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.02.046
更新日期:2006-05-30 00:00:00
abstract::Two rat lines bred for kindling susceptibility were previously observed to engage in different behavioral strategies in tests of emotionality. In order to extend past research on defensive behaviors in these strains which largely used males, Fast- and Slow-kindling females were assessed for anxiety-like behaviors in a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2008.08.090
更新日期:2008-11-13 00:00:00
abstract::This study examined the involvement of N-methyl-D-aspartate receptors (NMDARs) in experience-dependent synaptic plasticity. Rats chronically received an NMDA receptor antagonist (AP5) or saline (SAL) and were exposed to individual cages (IC) or environmental enrichment (EC). AP5 impaired measures of hippocampal-depend...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02379-9
更新日期:2000-07-14 00:00:00
abstract::We have shown that high-concentration albumin therapy is markedly neuroprotective in focal cerebral ischemia. The present study was conducted to ascertain the degree to which hemodynamic alterations are responsible for this therapeutic effect. Normothermic, physiologically regulated male Sprague-Dawley rats received a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00674-x
更新日期:1998-08-31 00:00:00
abstract::1-(p-Bromobenzoyl)-piperazine-2,3-dicarboxylic acid (pBB-PzDA; 0.03-5 mM), an excitatory amino acid antagonist, was perfused through the guinea pig cochlea while monitoring various cochlear potentials. pBB-PzDA (1-5 mM) reversibly suppressed the amplitude of the compound action potential of the auditory nerve (CAP) an...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90934-7
更新日期:1989-05-15 00:00:00
abstract::Phospholipid extracts from 48 intracranial tumors were analyzed using 31P NMR. Phospholipids commonly identified in the tumor spectra included phosphatidylglycerol (PG), phosphatidic acid (PA), diphosphatidylglycerol (DPG), uncharacterized phospholipid (U), ethanolamine plasmalogen (EPLAS), phosphatidylethanolamine (P...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91041-3
更新日期:1994-06-27 00:00:00
abstract::The effects of glucagon injections (25, 100 and 200 ng) into the paraventricular nucleus of the hypothalamus (PVN) were investigated in an open-circuit calorimeter. Wistar rats were tested, with no food available during the tests. High doses of glucagon (100 and 200 ng) produced small and short-lasting increases in en...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)90663-8
更新日期:1993-12-10 00:00:00
abstract::We have investigated, in 9 normal subjects, the time course of amplitude changes in the automatic long latency stretch reflex of wrist flexors during the preparatory period as a function of the precued direction of hand movement. Subjects maintained right hand position against a weak force and learned to compensate pr...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)91172-1
更新日期:1983-11-28 00:00:00
abstract::Perinatal exposure to cannabinoids has been shown to elicit central nervous system impairment in rodents. This includes changes in monoaminergic and neuropeptidergic activities. We have examined the effect of perinatal exposure to delta 9-tetrahydrocannabinol (delta 9-THC) on sensitivity to radiant heat in both male a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00255-o
更新日期:1995-05-22 00:00:00
abstract::Converging evidence suggests that compromised motor abilities in hemiparetic cerebral palsy are not solely due to impairments in motor execution, but are also related to deficits in action planning. The present study had two aims. First, we compared grip planning in a sequential task between participants with left-sid...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2008.12.074
更新日期:2009-03-19 00:00:00
abstract::In order to explore the anatomical nature of the inhibitory GABAergic control of cerebral serotonergic neurons exerted at the level of the anterior raphé cells in the rat, we have studied the effect of GABA agonist agents (given systemically or infused locally into the raphé dorsalis or medianus) on cerebral 5-hydroxy...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90717-6
更新日期:1985-04-01 00:00:00
abstract::Excitatory actions of acromelic acid were investigated in the isolated newborn rat spinal cord. Test compounds were added to the perfusing fluid and the responses were recorded from the ventral root extracellularly. Acromelic acid caused a depolarizing response in a dose-dependent manner and the depolarizing activity ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)90456-8
更新日期:1988-12-06 00:00:00
abstract::Cultures of neonatal mouse cortical astrocytes synthesized NGF mRNA and released immunoreactive NGF (ir-NGF) into the culture medium. Addition of 10 microM guanosine or GTP to the cultures increased ir-NGF release by 6 and 2 fold, respectively, after 24 h, and increased NGF mRNA 6 fold after 4 h and 2-3 fold after 24 ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00156-k
更新日期:1995-04-17 00:00:00