Abstract：
:A special feature of the extracellular matrix in adult brains of various species is the concentration of certain components around different sub-populations of neurones, giving rise to net-like structures termed perineuronal nets. Recently, some of these components have been identified but the function of these nets has yet to be resolved. Using immunofluorescence microscopy, we report here that phosphacan, a chondroitin sulphate proteoglycan, is an additional component of Wisteria floribunda labelled perineuronal nets surrounding parvalbumin-expressing neurones in rat cerebral cortex. Glycoproteins such as tenascin-C and -R have been identified in perineuronal nets and the present detection of phosphacan immunoreactivity in the same entity is of potential physiological importance because of their previously described interactions.
journal_name
Brain Resjournal_title
Brain researchauthors
Haunso A,Celio MR,Margolis RK,Menoud PAdoi
10.1016/s0006-8993(99)01596-6subject
Has Abstractpub_date
1999-07-10 00:00:00pages
219-22issue
1-2eissn
0006-8993issn
1872-6240pii
S0006-8993(99)01596-6journal_volume
834pub_type
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