Corticotropin-releasing factor mRNA is expressed in the inferior olives of rodents and primates.

Abstract:

:Immunohistochemical studies have suggested that corticotropin-releasing factor (CRF) was a transmitter of the olivocerebellar projection. We used in situ hybridization histochemistry with a 35S-labeled oligodeoxyribonucleotide probe for CRF mRNA to show that inferior olivary neurons of rats, baboons, and humans synthesize CRF.

journal_name

Brain Res

journal_title

Brain research

authors

Young WS 3rd,Walker LC,Powers RE,De Souza EB,Price DL

doi

10.1016/0169-328x(86)90010-0

subject

Has Abstract

pub_date

1986-11-01 00:00:00

pages

189-92

issue

2

eissn

0006-8993

issn

1872-6240

journal_volume

387

pub_type

杂志文章
  • Effects of brain-derived neurotrophic factor and nerve growth factor on remaining neurons in the lesioned nucleus basalis magnocellularis.

    abstract::Rats received a unilateral lesion of the nucleus basalis magnocellularis (NBM) by infusion of ibotenic acid. Starting 2 weeks after the lesion, the animals were treated with nerve growth factor (NGF) or brain-derived neurotrophic factor (BDNF) by intraparenchymal infusion of 3 micrograms per day for 4 weeks. Lesioned ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91775-2

    authors: Dekker AJ,Fagan AM,Gage FH,Thal LJ

    更新日期:1994-03-07 00:00:00

  • Microdialysis evidence that acetylcholine in the nucleus accumbens is involved in morphine withdrawal and its treatment with clonidine.

    abstract::This study used microdialysis to measure changes in extracellular acetylcholine (ACh) content in the nucleus accumbens (NAC) of freely moving rats during acute and chronic morphine treatment, and following naloxone-precipitated withdrawal. Morphine injection (20 mg/kg, i.p.) caused a significant decrease in extracellu...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)91616-9

    authors: Rada P,Pothos E,Mark GP,Hoebel BG

    更新日期:1991-10-11 00:00:00

  • Adaptive modeling of the unattended acoustic environment reflected in the mismatch negativity event-related potential.

    abstract::The mismatch negativity (MMN) event-related potential is elicited by changes in repetitive auditory stimuli. The present paper suggests that: (1) an acoustic model of the auditory environment is maintained even in the absence of attention focussed on auditory stimuli, preattentively detecting repetitive features of th...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(96)01008-6

    authors: Winkler I,Karmos G,Näätänen R

    更新日期:1996-12-02 00:00:00

  • Time- and dose-dependent effects of the serotonergic agent quipazine on regional cerebral metabolism in rats.

    abstract::The time course and the relation to dose of regional cerebral metabolic rates for glucose (rCMRglc) were measured in awake male adult Fischer-344 rats after administration of quipazine, a serotonin 5-HT2-3 receptor agonist. rCMRglc was determined, using the quantitative autoradiographic [14C]deoxyglucose technique, in...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)91380-b

    authors: Freo U,Ricchieri GL,Holloway HW,Soncrant TT

    更新日期:1993-01-15 00:00:00

  • Response of newborn and adult sheep to pyrogens: relation between fever and brain eicosanoid changes.

    abstract::We investigated whether the weak febrile response to pyrogens in newborns is due to a diminished activation of the putative pyrogen mediator, prostaglandin (PG)E2. Indwelling cannulas in the third ventricle of lambs (age, 5-31 days) and adult ewes were used to collect cerebrospinal fluid (CSF) for radioimmunoassay of ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00946-n

    authors: Coceani F,Bishai I,Engelberts D,House RV,Adamson SL

    更新日期:1995-11-27 00:00:00

  • Nicotinic acetylcholine binding sites in Alzheimer's disease.

    abstract::In Alzheimer's disease (AD), there is a loss of presynaptic cholinergic markers in the cerebral cortex, but the nature of cholinergic receptor changes is unclear. In this study, [3H]acetylcholine and [3H]nicotine were used to label nicotinic cholinergic binding sites in cerebral cortical tissues obtained at autopsy fr...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)90819-x

    authors: Whitehouse PJ,Martino AM,Antuono PG,Lowenstein PR,Coyle JT,Price DL,Kellar KJ

    更新日期:1986-04-16 00:00:00

  • The involvement of brain-derived neurotrophic factor in the pattern generator of mastication.

    abstract::Brain-derived neurotrophic factor (BDNF) is a family of neurotrophins that plays crucial roles in neural development, survival, maintenance and regeneration both in central and peripheral nervous systems. To examine the effects of BDNF on mastication, jaw movement trajectories and masticatory muscle activities were el...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2004.04.061

    authors: Okayasu I,Yamada Y,Maeda T,Yoshida N,Koga Y,Oi K

    更新日期:2004-07-30 00:00:00

  • Nuclear orphan receptor Nor-1 contributes to depressive behavior in the Wistar-Kyoto rat model of depression.

    abstract::The current study explored the effects of prolonged antidepressant treatment on mRNA levels of two nuclear receptors in specific brain regions of an animal model of depression, the Wistar-Kyoto (WKY) rat. Both nuclear receptors have been implicated in the development or treatment of depression. The expression of nucle...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2010.09.041

    authors: Schaffer DJ,Tunc-Ozcan E,Shukla PK,Volenec A,Redei EE

    更新日期:2010-11-29 00:00:00

  • Nitric oxide modulates NMDA-induced increases in intracellular Ca2+ in cultured rat forebrain neurons.

    abstract::We studied the effects of nitric oxide (NO) and the NO-releasing agents sodium nitroprusside (SNP), S-nitroso-N-acetylpenicillamine (SNAP) and isosorbide dinitrate (ISDN) on N-methyl-D-aspartate (NMDA)-induced increases in intracellular Ca2+ ([Ca2+]i), whole-cell patch-clamp currents and on glutamate-stimulated [3H]di...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)91690-g

    authors: Hoyt KR,Tang LH,Aizenman E,Reynolds IJ

    更新日期:1992-10-02 00:00:00

  • The effects of reversible inactivation of postero-temporal visual cortex on neuronal activities in cat's area 17.

    abstract::'Spontaneous' and visually evoked action potentials were recorded from single neurons in cytoarchitectonic area 17 (striate cortex, area V1) of anaesthetized and immobilized cats, prior to, during and after brief reversible inactivation of the ipsilateral postero-temporal visual (PTV) cortex (presumed homologue of pri...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.12.081

    authors: Huang JY,Wang C,Dreher B

    更新日期:2007-03-23 00:00:00

  • Dopamine receptors in the ventral tegmental area affect motor, but not motivational or reflexive, components of copulation in male rats.

    abstract::Microinjection of apomorphine into the ventral tegmental area (VTA) of male rats was previously shown to delay the onset of copulation and slow its rate, presumably by stimulating impulse-regulating autoreceptors on cell bodies of the A10 mesocorticolimbic dopamine tract. Such stimulation would be expected to slow the...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)90173-s

    authors: Hull EM,Weber MS,Eaton RC,Dua R,Markowski VP,Lumley L,Moses J

    更新日期:1991-07-19 00:00:00

  • Survival and mitogenesis of neuroepithelial cells are influenced by noradrenergic but not cholinergic innervation in cultured embryonic rat neopallium.

    abstract::alpha-Adrenoreceptors are present in the ventricular (VZ) and subventricular (SVZ) zones of the mammalian embryonic forebrain, and contribute towards cell cycle controls in the germinal neuroepithelium [Pabbathi et al., Brain Res. 760 (1997) 22-33.]. Since noradrenaline-containing fibres from the locus coeruleus (LC) ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)02242-8

    authors: Popovik E,Haynes LW

    更新日期:2000-01-24 00:00:00

  • Sites in the male primate brain at which testosterone acts as an androgen.

    abstract::Quantitative autoradiographic analysis was used to identify regions in the brain of the male primate where androgen binding sites may be involved in the actions of testosterone. Three days after castration, adult male rhesus monkeys received a subcutaneous injection of either dihydrotestosterone propionate (DHTP, 20 m...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)90456-3

    authors: Michael RP,Rees HD,Bonsall RW

    更新日期:1989-11-13 00:00:00

  • In situ enzymatic activity of transglutaminase isoforms on brain tissue sections of rodents: A new approach to monitor differences in post-translational protein modifications during neurodegeneration.

    abstract::Mammalian transglutaminases (TGs) catalyze the irreversible post-translational modifications of proteins, the most prominent of which is the calcium-dependent formation of covalent acyl transfers between the γ-carboxamide group of glutamine and the ε-amino-group of lysine (GGEL-linkage). In the central nervous system,...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2015.11.027

    authors: Schulze-Krebs A,Canneva F,Schnepf R,Dobner J,Dieterich W,von Hörsten S

    更新日期:2016-01-15 00:00:00

  • Dopamine receptors regulate Met-enkephalin content in pituitary.

    abstract::Met-enkephalin-like immunoreactive material (ME-LI) in the neurointermediate lobe of rat pituitary was dramatically altered by the long-term administration of drugs altering dopamine receptor activity. Treatment with the dopamine receptor antagonist haloperidol resulted in significant increases of ME-LI and treatment ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90586-4

    authors: George SR,Kertesz M

    更新日期:1985-05-13 00:00:00

  • Conditional immortalization of neuronal cells from postmitotic cultures and adult CNS.

    abstract::To determine whether postmitotic neurons can be immortalized by oncogenic transduction, we used two approaches involving conditional expression of a temperature-sensitive SV40 large T antigen (Tts). Initially, Tts was introduced into E17 rat embryonal hippocampal cells that were then cultured at the non-permissive tem...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91484-2

    authors: Eves EM,Kwon J,Downen M,Tucker MS,Wainer BH,Rosner MR

    更新日期:1994-09-12 00:00:00

  • Localizing the corticospinal neurons in neonatal, developing and mature albino rat.

    abstract::Following the administration of horseradish peroxidase (HRP) in the middle or lower cervical cord segments of neonatal (1-10 days), developing (15-20 days) and mature (2-4 months) albino rats, labeled pyramidal neurons were found in layer V of the cerebral cortex. They formed one continuous band of labeled neurons in ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)91327-6

    authors: Leong SK

    更新日期:1983-04-11 00:00:00

  • Probing amyloid beta-induced cell death using a fluorescence-peptide conjugate in Alzheimer's disease mouse model.

    abstract::With the increasing worldwide incidence of Alzheimer's disease (AD), there is a critical need for the discovery of more effective diagnostic methods. However, development of diagnostic tools in AD has been hindered by obstacles such as the absence of exact biomarkers. Apoptosis caused by amyloid-β (Aβ) plays an import...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2016.06.041

    authors: Lee JK,Wang K,Park MH,Kim N,Lee JY,Jin HK,Kim IS,Lee BH,Bae JS

    更新日期:2016-09-01 00:00:00

  • Evidence for a neural inhibitory factor which downregulates fetal-type acetylcholine receptor expression in skeletal muscle cell lines.

    abstract::Nerve-evoked muscle depolarisation plays an important role in the downregulation of extrasynaptic AChRs which accompanies the increase in synaptic AChR expression at the neuromuscular junction during embryonic development. However, additional mechanisms may be involved in the AChR downregulation. This study provides e...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(98)01313-4

    authors: Montgomery JM,Fleming JS,Mills RG

    更新日期:1999-02-13 00:00:00

  • Partial damage to the noradrenergic bundle increases tyrosine hydroxylase activity in noradrenergic terminals of hippocampus but not cerebellum.

    abstract::Intracerebral administration of 6-hydroxydopamine (6-HDA) along the dorsal noradrenergic bundle produced a gradual and long-lasting decrease of norepinephrine (NE) in hippocampus. This decrease in NE levels initially was accompanied by a parallel decrease in the activity of the rate-limiting enzyme for NE biosynthesis...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(84)90056-8

    authors: Fluharty SJ,Stricker EM,Zigmond MJ

    更新日期:1984-12-24 00:00:00

  • Long-term survival and development of dissociated parasympathetic neurons in culture.

    abstract::Ciliary ganglion neurons from chick embryo were grown in cell culture following enzymatic and mechanical dissociation. The culture conditions necessary for long-term (greater than 21 days) survival of the isolated neurons were investigated. Neurons could be cultured with and without non-neural cells by adjusting the c...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(80)90127-4

    authors: Tuttle JB,Suszkiw JB,Ard M

    更新日期:1980-02-03 00:00:00

  • Multimodal exercises simultaneously stimulating cortical and brainstem pathways after unilateral corticospinal lesion.

    abstract::In the context of injury to the corticospinal tract (CST), brainstem-origin circuits may provide an alternative system of descending motor influence. However, subcortical circuits are largely under subconscious control. To improve volitional control over spared fibers after CST injury, we hypothesized that a combinati...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2013.07.012

    authors: Harel NY,Yigitkanli K,Fu Y,Cafferty WB,Strittmatter SM

    更新日期:2013-11-13 00:00:00

  • Non-dopaminergic mechanisms in the turning behavior evoked by intranigral opiates.

    abstract::The turning effects of the unilateral intranigral injection of morphine and of different analogs of dynorphin and enkephalin were studied. All injections were made in awake rats through cronically implanted guide cannulae. Dynorphin1-13 at a dose of 10 micrograms (0.6 nmol) and dynorphin1-17 at a dose of 2 micrograms ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)91074-1

    authors: Morelli M,Di Chiara G

    更新日期:1985-08-26 00:00:00

  • Disinhibition of the hypothalamic paraventricular nucleus increases mean circulatory filling pressure in conscious rats.

    abstract::Venous capacitance plays an important role in the control of cardiac output. However, the central nervous system sites and neurochemical signals involved in modulating venous function remain to be fully elucidated. The hypothalamic paraventricular nucleus (PVN) is an important site modulating autonomic outflow to the ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00128-5

    authors: Martin DS,Rodrigo MC,Egland MC,Barnes LU

    更新日期:1997-05-09 00:00:00

  • Activation of mu opioid receptors in the nucleus raphe dorsalis blocks apomorphine-induced aggression in rats: serotonin appears not to be involved.

    abstract::The role of mu opioid receptors in the nucleus raphe dorsalis (DR) in the control of apomorphine-induced aggression was studied in rats. Administration in the DR of a selective mu opioid receptor agonist, (D-Ala2,N-Me-Phe4,Gly5-ol)-enkephalin (DAGO), in doses ranging from 0.01 to 1 microgram/0.5 microliter, dose-depen...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)90706-3

    authors: Giraud O,Cervo L,Grignaschi G,Samanin R

    更新日期:1989-05-29 00:00:00

  • Long-term castration effects motoneuron size but not number in the spinal nucleus of the bulbocavernosus in the adult male Mongolian gerbil.

    abstract::The spinal nucleus of the bulbocavernosus (SNB) is a sexually dimorphic group of motoneurons in Rexed's Lamina X of the lumbosacral spinal cord of the Mongolian gerbil. The SNB innervates the perineal musculature, the bulbocavernosus (BC), levator ani (LA), and external anal sphincter (EAS). Recent studies demonstrate...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(02)02949-9

    authors: Fraley GS,Ulibarri CM

    更新日期:2002-10-25 00:00:00

  • Quisqualic acid induced sensitization and the active uptake of L-quisqualic acid by hippocampal slices.

    abstract::Hippocampal CA1 pyramidal cell neurons are sensitized to depolarization by L-2-amino-4-phosphonobutanoic acid (L-AP4) following exposure to L-quisqualic acid (QUIS). It has been proposed that induction of this 'QUIS-effect' involves uptake of L-QUIS by hippocampal cells. We have used o-phthaldialdehyde (OPA) derivatiz...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)91359-z

    authors: Schulte MK,Roon RJ,Koerner JF

    更新日期:1993-03-05 00:00:00

  • Catecholamine alterations in basal ganglia after hippocampal lesions.

    abstract::Rats were given sham, cortical, or hippocampal lesions and sacrificed 7 or 28 days following surgery. Levels of norepinephrine, dopamine, and the major dopamine metabolites, 3,4-dihydroxyphenylacetic acid and homovanillic acid (HVA), were assayed in 3 brain regions. At day 7 there was a decrease in dopamine utilizatio...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(82)90996-9

    authors: Springer JE,Isaacson RL

    更新日期:1982-12-02 00:00:00

  • ERP correlates of the conflict level in the multi-response Stroop task.

    abstract::This EEG study (N=33) examined event-related potentials associated with conflict between activated responses in the Stroop task, in order to examine the conflict monitoring theory of cognitive control, which predicts the strength of exerted control to be proportional to the detected level of conflict. However, existin...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2016.08.041

    authors: Chuderski A,Senderecka M,Kałamała P,Kroczek B,Ociepka M

    更新日期:2016-11-01 00:00:00

  • Modality matters: the effects of stimulus modality on the 4- to 30-Hz brain electric oscillations during a lexical decision task.

    abstract::The aim of the current study was to assess modality-specific brain oscillatory responses during cognitive processing. Brain oscillatory ERD/ERS responses of the 4- to 30-Hz EEG frequency bands were examined during lexical decision where the task is to identify whether the presented stimulus is a word or a pseudoword. ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.06.100

    authors: Krause CM,Grönholm P,Leinonen A,Laine M,Säkkinen AL,Söderholm C

    更新日期:2006-09-19 00:00:00