SPARC, an extracellular matrix glycoprotein containing the follistatin module, is expressed by astrocytes in synaptic enriched regions of the adult brain.

abstract：:In teleosts, the fasciculus medialis tractus optici departs the optic tract and follows an aberrant path towards the midbrain tectum. To determine the retinal origin of the fascicle, horseradish peroxidase was injected into localized lesions of either the optic nerve or the retina. The fasciculus medialis axons of adu...

journal_title：Brain research

authors： Fraley SM,Sharma SC

更新日期：1985-07-01 00:00:00

abstract：:The response of trunk neural crest cells taken from precise levels of the neural axis and cultured together with adjacent somites to Brain-derived neurotrophic factor (BDNF), was examined in cultures grown in a chemically defined medium. In control cultures, the number of neural crest-derived neurons expressing the HN...

journal_title：Brain research

authors： Kalcheim C,Gendreau M

更新日期：1988-06-01 00:00:00

abstract：:A carbohydrate epitope on adhesion proteins of the developing nervous system, and on myelin-associated glycoprotein, is recognized by the monoclonal antibody HNK-1. The HNK-1 epitope bearing proteins and the monoclonal antibody alter, in a dose-dependent manner, the interaction between neurons and neurite-promoting su...

journal_title：Brain research

authors： Riopelle RJ,McGarry RC,Roder JC

更新日期：1986-03-05 00:00:00

abstract：:In WAG/Rij rat genetic model of absence epilepsy, the first spike-wave discharges (EEG hallmark of absence epilepsy) are known to appear after puberty, and their incidence increases with age. WAG/Rij rats are known to have a genetic predisposition to absence epilepsy, and further development of epilepsy might be influ...

journal_title：Brain research

authors： Sitnikova E,Rutskova EM,Raevsky VV

更新日期：2015-01-12 00:00:00

abstract：:These experiments examined the effects of intra-amygdala injections of NMDA receptor antagonists on the acquisition and retention of inhibitory avoidance. In Expt. I, rats received bilateral intra-amygdala injections of the NMDA antagonists D,L-AP5 (1-10 micrograms), D-AP5 (0.03-1 micrograms), CPP (0.125 or 0.375 micr...

journal_title：Brain research

authors： Kim M,McGaugh JL

更新日期：1992-07-10 00:00:00

abstract：:Rhyme processing is reflected in the electrophysiological signals of the brain as a negative deflection for non-rhyming as compared to rhyming stimuli around 450 ms after stimulus onset. Studies have shown that this N450 component is not solely sensitive to rhyme but also responds to other types of phonological overla...

journal_title：Brain research

authors： Wagensveld B,Segers E,Alphen Pv,Hagoort P,Verhoeven L

更新日期：2012-11-05 00:00:00

abstract：:Following the intraventricular injection of a small amount of [3H]5-hydroxytryptamine ([3H]5-HT), the amount of radioactivity in telencephalic structures on the injected side was 6--7 times larger than that in corresponding areas on the opposite side. Moreover, a multiphasic disappearance of [3H]5-HT from whole brain ...

journal_title：Brain research

authors： Gallager DW,Sanders-Bush E,Aghajanian GK,Sulser F

更新日期：1975-07-25 00:00:00

abstract：:Hippocampal soluble fraction stimulates acetylcholine (AcCho) synthesis of medial septal nuclei in explant culture system. This stimulating activity was purified from 10-12-day-old rat hippocampus. During purification, the activity was separated into two fractions and a previously unreported peptide was purified from ...

journal_title：Brain research

authors： Ojika K,Kojima S,Ueki Y,Fukushima N,Hayashi K,Yamamoto M

更新日期：1992-02-14 00:00:00

abstract：:A startle-like response can be evoked at low currents by one-pulse electrical stimulation of reticular formation sites from the rostrolateral pons to the caudomedial medulla. To test whether this response is mediated by the same reticular formation neurons as those that mediate the acoustic startle, we delivered a bri...

journal_title：Brain research

authors： Yeomans JS,Cochrane KA

更新日期：1993-07-23 00:00:00

abstract：:The response of granule cells and CA1 pyramidal neurones to NMDA was studied in the presence and absence of Mg2+ using an in vitro slice preparation. In the absence of Mg2+ the depolarizing response of hippocampal neurones to NMDA is accompanied by a decrease in input resistance. In the presence of Mg2+ ions, however,...

journal_title：Brain research

authors： Crunelli V,Mayer ML

更新日期：1984-10-08 00:00:00

abstract：:When rabbit retinas are exposed in vitro to specific excitatory amino acid receptor agonists certain GABAergic amacrine cells are activated to cause a release of GABA. The GABA that is not released can be detected by immunohistochemistry. Exposure of tissues to kainate or NMDA each caused a characteristic change in th...

journal_title：Brain research

authors： Osborne NN,Pergande G,Block F,Schwarz M

更新日期：1994-12-26 00:00:00

abstract：:Neovascularization within syngeneic rat fetal neocortical grafts transplanted into a previously prepared cavity in the cerebral cortex was studied 1 to 3 months after transplantation, utilizing scanning electron microscopy of vascular corrosion casts. The grafts were easily identified and the outer surface of the graf...

journal_title：Brain research

authors： Miyoshi Y,Date I,Ohmoto T

更新日期：1995-05-29 00:00:00

abstract：:Female rats were subjected to unilateral left or right, bilateral, or sham ablation of the cerebral cortex. Eight weeks after surgery, the rats were sacrificed by decapitation and spleen cells were grown in culture for 96 h in the presence or absence of the T-cell mitogen concanavalin A or the B-cell mitogen lipopolys...

journal_title：Brain research

authors： LaHoste GJ,Neveu PJ,Mormède P,Le Moal M

更新日期：1989-03-27 00:00:00

abstract：:Protein uptake and transport within the brain stem vasculature of mechanically brain injured cats was studied by means of both light and electron microscopy utilizing intravenously injected horseradish peroxidase as the protein tracer. In animals sustaining low grade head injuries not of sufficient intensity to elicit...

journal_title：Brain research

authors： Povlishock JT,Becker DP,Sullivan HG,Miller JD

更新日期：1978-09-22 00:00:00

abstract：:To investigate the role of the estrogen receptor (ER) in mediating neuroprotection, the neuroprotective profiles of selective ER agonists for ERalpha and ERbeta, propylpyrazole triol (PPT) and 2,3-bis(4-hydroxyphenyl) proprionitrile (DPN), respectively, were compared to that of 17beta-estradiol and 17alpha-estradiol i...

journal_title：Brain research

authors： Cordey M,Pike CJ

更新日期：2005-05-31 00:00:00

abstract：:Previous studies have demonstrated that postnatal (days 2-29 of life) administration of lead (200 mg/kg/day by gavage) to Long-Evans rats caused permanent increases in lithium-induced polydipsia (LIP). These lead-induced increases in LIP were apparently not of renal origin, did not occur in animals treated with lead a...

journal_title：Brain research

authors： DeHaven DL,Krigman MR,Gaynor JJ,Mailman RB

更新日期：1984-04-16 00:00:00

abstract：:The exposure of cultured rat striatal neurons to L-DOPA caused marked cell death. The L-DOPA cytotoxicity was inhibited by the addition of Mg2+ to and by the removal of Ca2+ from the culture medium, and also by the application of tetrodotoxin. Moreover, prolonged application of L-DOPA increased the glutamate content i...

journal_title：Brain research

authors： Maeda T,Cheng N,Kume T,Kaneko S,Kouchiyama H,Akaike A,Ueda M,Satoh M,Goshima Y,Misu Y

更新日期：1997-10-10 00:00:00

abstract：:This study was conducted on unanesthetized rainbow trout equipped with two ECG electrodes and with an intracerebroventricular (i.c.v.) micro-guide. The ECG signal was recorded during three experimental sessions of 30 min and the heart rate variability (HRV) spectral analysis was performed during stabilized periods of ...

journal_title：Brain research

authors： Le Mével JC,Mimassi N,Lancien F,Mabin D,Boucher JM,Blanc JJ

更新日期：2002-08-23 00:00:00

abstract：:The immunocytochemical localization of L-glutamate decarboxylase (GAD), the enzyme which which forms gamma-aminobutyric acid (GABA), has been studied in developing rodent cerebellum. During the first 3-4 postnatal days, GAD is distributed along non-terminal portions of axonal processes in close association with small ...

journal_title：Brain research

authors： McLaughlin BJ,Wood JG,Saito K,Roberts E,Wu JY

更新日期：1975-03-07 00:00:00

abstract：:A novel and convenient assay was used to determine the effect of recombinant Interleukin-2 (IL-2) on the function of the blood-brain barrier (BBB). The assay is based on a variant of the West Nile virus, WN-25, which had lost its neuroinvasiveness but not its neurovirulence. WN-25, when injected intravenously, can cau...

journal_title：Brain research

authors： Kobiler D,Lustig S,Gozes Y,Ben-Nathan D,Akov Y

更新日期：1989-09-04 00:00:00

abstract：:The present study examined the effect of chronic paroxetine (10 mg/kg p.o., 21 days) on the 5-HT1B and 5-HT1D autoreceptors controlling 5-HT efflux in slices of rat ventrolateral geniculate nucleus. Electrically stimulated 5-HT efflux (10 pulses, 200 Hz, 0.1 ms, 10 mA) was measured using fast cyclic voltammetry. Peak ...

journal_title：Brain research

authors： Davidson C,Stamford JA

更新日期：1997-06-20 00:00:00

abstract：:Intracerebroventricular (i.c.v.) administration of corticotropin-releasing factor (CRF) biphasically affects performance in tests of learning and memory. In the present study, we used CRF, urocortin (Ucn), a recently cloned CRF homologue, and CRF receptor antagonists, to determine which CRF receptor subtype(s) mediate...

journal_title：Brain research

authors： Zorrilla EP,Schulteis G,Ormsby A,Klaassen A,Ling N,McCarthy JR,Koob GF,De Souza EB

更新日期：2002-10-18 00:00:00

abstract：:Data reported up to now on neuron-glia relationships, show that neuron cell bodies and glial cells are separated by a narrow intercellular cleft which is considered as the microenvironment of the nervous system, and where neuron-glia exchange occurs. We present here evidence that neuron perikarya and ensheathing glial...

journal_title：Brain research

authors： Cuadras J,Martin G,Czternasty G,Bruner J

更新日期：1985-02-04 00:00:00

abstract：:Headache medicine is primarily dependent on patients' subjective reports of pain, which are assessed at diagnosis and throughout the duration of treatment. There is a need for an objective, quantitative biological measurement of headache pain severity. In this study, quantitative sensory testing (QST) was conducted vi...

journal_title：Brain research

authors： Nguyen RH,Ford S,Calhoun AH,Holden JK,Gracely RH,Tommerdahl M

更新日期：2013-03-01 00:00:00

abstract：:We studied the effect of the cortical projection from the basal forebrain on the cerebral cortical metabolism using positron emission tomography (PET) with [(18)F] fluorodeoxyglucose. Unilateral damage of the nucleus basalis magnocellularis (NBM) did not cause a permanent reduction of cortical metabolism: recovery was...

journal_title：Brain research

authors： Katsumi Y,Hanakawa T,Fukuyama H,Hayashi T,Nagahama Y,Yamauchi H,Ouchi Y,Tsukada H,Shibasaki H

更新日期：1999-08-07 00:00:00

abstract：:Tetramethylpyrazine (TMP) is one of the alkaloids contained in Ligustrazine which has been used in traditional Chinese medicine as an analgesic for injury and dysmenorrhea. ATP can elicit the sensation of pain. This study observed the effects of TMP on ATP-activated current (IATP) in rat DRG neurons. TMP (0.1-1 mM) co...

journal_title：Brain research

authors： Liang SD,Xu CS,Zhou T,Liu HQ,Gao Y,Li GL

更新日期：2005-04-08 00:00:00

abstract：:The suprachiasmatic nuclei receive photic input information directly through a retinohypothalamic tract (RHT) and indirectly through a projection from the intergeniculate leaflet of the lateral geniculate complex, the geniculohypothalamic tract (GHT). Prior work has established that the RHT is sufficient for entrainme...

journal_title：Brain research

authors： Johnson RF,Moore RY,Morin LP

更新日期：1988-09-20 00:00:00

abstract：:Previous studies have reported that schizophrenia (SZ) patients showed selective reinforcement learning deficits and abnormal feedback-related event-related potential (ERP) components. However, how the brain networks and their topological properties evolve over time during transient feedback-related cognition processi...

journal_title：Brain research

authors： Zhao Z,Wang C,Yuan Q,Zhao J,Ren Q,Xu Y,Li J,Yu Y

更新日期：2020-11-01 00:00:00

abstract：:We utilized proton magnetic resonance spectroscopy to evaluate the metabolic profile of the hippocampus and anterior cingulate cortex of the developing rat brain from postnatal days 14-70. Measured metabolite concentrations were modeled using linear, exponential, or logarithmic functions and the time point at which th...

journal_title：Brain research

authors： Ramu J,Konak T,Liachenko S

更新日期：2016-11-15 00:00:00

abstract：:Human arachnoid villi were studied ultrastructurally to clarify the mechanism of cerebrospinal fluid absorption. Arachnoid villi of humans showed quite different features from those of animals. The former were not always invested with endothelial linings as previously reported in the latter. Instead, there was a cover...

journal_title：Brain research

authors： Yamashima T

更新日期：1986-10-01 00:00:00