Reduction of epileptic spike-wave activity in WAG/Rij rats fostered by Wistar dams.

abstract：:Endothelin (ET), a potent vasoconstrictor peptide, is believed to have central sites of action and potential neurohormonal effects relating to body fluid homeostasis and blood-pressure regulation. Systemic endothelin binds to receptors at circumventricular organs and has been shown to increase plasma concentrations of...

journal_title：Brain research

authors： Wall KM,Nasr M,Ferguson AV

更新日期：1992-01-20 00:00:00

abstract：:Swelling of glial and nerve cells is characteristic of brain damage in cerebral ischemia or trauma. The therapeutical efficiency of inhibition of Cl(-)-transport by a novel antagonist, the diuretic torasemide, on cytotoxic swelling of glial cells from lactacidosis, or glutamate was analyzed. Lactacidosis and the inter...

journal_title：Brain research

authors： Staub F,Peters J,Kempski O,Schneider GH,Schürer L,Baethmann A

更新日期：1993-04-30 00:00:00

abstract：:A newly discovered cell-to-cell communication system involves small, membrane-enveloped nanovesicles, called exosomes. We describe here how these extracellular nanoparticles were discovered and how it became gradually apparent that they play fundamental roles in regulation of physiological functions and pathological p...

journal_title：Brain research

authors： Kawikova I,Askenase PW

更新日期：2015-08-18 00:00:00

abstract：:It is well known that the nerve growth factor (NGF) may serve as a link between inflammation and hyperalgesia. Recent experiments showed that systemic injection of NGF dramatically stimulated the expression of brain-derived neurotrophic factor (BDNF) mRNA in the dorsal root ganglion (DRG). In the present study, we eva...

journal_title：Brain research

authors： Cho HJ,Kim SY,Park MJ,Kim DS,Kim JK,Chu MY

更新日期：1997-02-28 00:00:00

abstract：:Brain cortico-striatal circuits have consistently been implicated in the pathology of addiction related disorders. We applied a reliable seed-based analysis of the resting-state brain activity to comprehensively delineate the subdivisions of striatal functional connectivity implicated in internet gaming disorder. Amon...

journal_title：Brain research

authors： Hong SB,Harrison BJ,Dandash O,Choi EJ,Kim SC,Kim HH,Shim DH,Kim CD,Kim JW,Yi SH

更新日期：2015-03-30 00:00:00

abstract：:In urethane-anesthetized cats, ordinary and partial coherence values relating the 10-Hz rhythmic discharges of sympathetic nerves located on opposite sides of the body were not significantly affected by midsagittal section of the spinal cord from the seventh cervical through eighth thoracic or first cervical through e...

journal_title：Brain research

authors： Zhong S,Gebber GL,Barman SM

更新日期：1995-01-30 00:00:00

abstract：:Different mechanisms have been suggested to contribute to isoflurane-mediated neuroprotection. Previous studies have suggested that the protein Slit can abrogate neuronal death in mixed neuronal-glial cultures exposed to oxygen-glucose deprivation (OGD) and reperfusion (OGD/R). We hypothesized that isoflurane increase...

journal_title：Brain research

authors： Zhao XC,Zhang LM,Li Q,Tong DY,Fan LC,An P,Wu XY,Chen WM,Zhao P,Wang J

更新日期：2013-11-06 00:00:00

abstract：:A study was undertaken of the possible relationship of the binding affinity of a series of anticholinergic psychotomimetic drugs to their psychopharmacological and anticholinergic effects. Binding was measured to brain homogenates and nerve endings using [3H]quinuclidinyl benzilate (QB), a highly potent psychotomimeti...

journal_title：Brain research

authors： Baumgold J,Abood LG,Aronstam R

更新日期：1977-03-25 00:00:00

abstract：:cGMP was proposed to be the agent which directly opens the light-sensitive channel in Limulus ventral photoreceptors. However, the light-sensitive rhabdomeral-lobe (R-lobe) is not uniformly responsive to cGMP injection; that is, there are 'hot spots' of sensitivity. A potent phosphodiesterase which rapidly hydrolyses ...

journal_title：Brain research

authors： Feng JJ,Frank TM,Fein A

更新日期：1991-06-28 00:00:00

abstract：:Fulfilled predictions lead to neural suppression akin to repetition suppression, but it is currently unclear if such effects generalize to broader stimulus categories in the absence of exact expectations. In particular, does expecting novelty alter the way novel stimuli are processed? In the present study, the effects...

journal_title：Brain research

authors： Schomaker J,Meeter M

更新日期：2018-09-01 00:00:00

abstract：:The microdialysis technique was utilized to study the effects of N-methyl-D-aspartate (NMDA) receptor ligands on the in vivo release of endogenous glutamate (Glu) and aspartate (Asp) from the rat striatum. Addition of NMDA (250 and 500 microM) to the dialysis perfusion solution resulted in a striking dose-dependent in...

journal_title：Brain research

authors： Bustos G,Abarca J,Forray MI,Gysling K,Bradberry CW,Roth RH

更新日期：1992-07-10 00:00:00

abstract：:Nuclear factor kappa B (NFkappaB) is a transcription factor which can be activated by some neurotrophic factors and cytokines, and then translocated into the nucleus. We examined NFkappaB immunoreactivity (IR) in L4 and L5 dorsal root ganglion (DRG) cells of normal rats, and 2 weeks after complete sciatic nerve transe...

journal_title：Brain research

authors： Ma W,Bisby MA

更新日期：1998-06-29 00:00:00

abstract：:Gabapentin, a drug useful in several neurological and psychiatric disorders, decreased K(+) (15 mM)-induced [Ca(2+)](i) increase in Fura-PE3-loaded rat neocortical synaptosomes (IC(50)=9.7 microM; submaximal inhibition of 28.6%). This effect may indicate a selective modulation of presynaptic Ca(2+) influx in response ...

journal_title：Brain research

authors： Meder WP,Dooley DJ

更新日期：2000-09-01 00:00:00

abstract：:The effects of recombinant mouse stem cell factor (rmSCF) on paired-pulse facilitation (PPF) and long-term potentiation (LTP) in the mossy fiber (MF)-CA3 pathway were examined in mouse hippocampal slices by recording field EPSPs. When PPF was measured before and 30 min after tetanic stimulation, the initial PPF positi...

journal_title：Brain research

authors： Kondo T,Katafuchi T,Hori T

更新日期：2002-08-16 00:00:00

abstract：:Chicks of 1-8 days after hatching were submitted to unilateral visual deprivation and, in both optic lobes, muscarinic receptors, labeled with L-[3H]quinuclidinyl benzylate [( 3H]L-QNB) and acetylcholinesterase (AChE) were assayed. Between 1 and 6 days the number of [3H]L-QNB binding sites was lower in the contralater...

journal_title：Brain research

authors： Jerusalinsky DA,De Robertis E

更新日期：1984-06-01 00:00:00

abstract：:It has recently been shown that the lobules 9 and 10 of the cerebellum contain high densities of dopamine D3 receptors (and almost no D2 receptors [Bouthenet, M.L., Souil, E., Martres, M.P., Sokoloff, P., Giros, B. and Schwartz, J.C., Brain Res., 564 (1991) 203-219; Sokoloff, P., Giros, B., Martres, M.P., Bouthenet, M...

journal_title：Brain research

authors： Barik S,de Beaurepaire R

更新日期：1996-10-21 00:00:00

abstract：:(1)The brain stem of anaesthetized cats has been mapped between Horsley-Clark planes APO and P8.5 with electrical stimuli of low intensity in order to determine the areas which can produce excitatory of inhibitory influences on the spontaneously contracting, sympathetically denervated, urinary bladder. (2) Two inhibit...

journal_title：Brain research

authors： McMahon SB,Spillane K

更新日期：1982-02-25 00:00:00

abstract：:To test the hypothesis that stimulation of glial peroxidase activity by estrogens may play a role in the pathogenesis of the previously reported degenerative changes in the hypothalamic arcuate nucleus that occur in female rats treated with a long-acting estrogen preparation, the cellular localization and number of pe...

journal_title：Brain research

authors： Schipper HM,Lechan RM,Reichlin S

更新日期：1990-01-22 00:00:00

abstract：:Previous studies employing systemic administration of the dopamine agonist apomorphine have shown that the dose response curves for apomorphine's effects on penile reflexes and seminal emission differ, suggesting that experimentally separable populations of dopamine receptors regulate these two responses. The present ...

journal_title：Brain research

authors： Pehek EA,Thompson JT,Hull EM

更新日期：1989-10-23 00:00:00

abstract：:Corticotropin-releasing factor (CRF) and dynorphin-related peptides are co-localized within a subset of hypothalamic neurons suggesting the possibility of their co-release. Therefore, studies were performed in conscious unrestrained rats to examine whether dynorphin-related peptides modify the central nervous system (...

journal_title：Brain research

authors： Overton JM,Fisher LA

更新日期：1989-05-29 00:00:00

abstract：:α4βδ GABA(A) receptors (GABARs) have low CNS expression, but their expression is increased by 48h exposure to the neurosteroid THP (3α-OH-5α[β]-pregnan-20-one). THP also increases the efficacy of δ-containing GABARs acutely, where GABA is a partial agonist. Thus, we examined effects of THP (100 nM) and full GABA agoni...

journal_title：Brain research

authors： Kuver A,Shen H,Smith SS

更新日期：2012-06-29 00:00:00

abstract：:Spontaneously firing units were recorded extracellularly from the hippocampus of anesthetized rats, and autocorrelograms were conventionally constructed. These conventional autocorrelograms were sorted into frequency-specific autocorrelograms according to the instantaneous firing frequency of the spike at Deltat=0, wh...

journal_title：Brain research

authors： Murata M,Kato N

更新日期：2007-02-16 00:00:00

abstract：:The neural manifestations of food avoidance learning in the mollusc, Pleurobranchaea, survive the surgical reduction of the preparation to the nearly isolated brain. These manifestations include increased synaptic inhibition and reduced synaptic excitation of the phasic paracerebral feeding command interneurons (PCps)...

journal_title：Brain research

authors： Kovac MP,Davis WJ,Matera EM,Morielli A,Croll RP

更新日期：1985-04-08 00:00:00

abstract：:Recent reports of the transsynaptic transfer of wheat germ agglutinin (WGA) in several systems are consistent with the hypothesis that WGA binds to endogenous glycoproteins(s) which undergo transsynaptic transfer. Such molecules might be involved in trophic interactions between neurons. Since these hypothetical glycop...

journal_title：Brain research

authors： Rhodes CH,Gonatas NK

更新日期：1986-12-03 00:00:00

abstract：:The behavioral and EEG effects of rat and ovine corticotropin releasing factor (r- and o-CRF) were compared. Both peptides were injected intracerebroventricularly into rats through chronically implanted cannulae. At the doses of 0.1 and 1 microgram both peptides activated the EEG and stimulated motor activity. At the ...

journal_title：Brain research

authors： Marrosu F,Mereu G,Fratta W,Carcangiu P,Camarri F,Gessa GL

更新日期：1987-04-07 00:00:00

abstract：:C3H/HeJ mice are refractory to lipolysaccharide (LPS) in the periphery, primarily because their macrophages do not respond to LPS and produce pro-inflammatory cytokines such as interleukin-1 (IL-1). To determine if they are also refractory to LPS in the brain, behavior of C3H/HeJ mice was compared to LPS-sensitive C3H...

journal_title：Brain research

authors： Johnson RW,Gheusi G,Segreti S,Dantzer R,Kelley KW

更新日期：1997-03-28 00:00:00

abstract：:A study was made of the release of excitatory, inhibitory and other amino acids from epileptic foci induced in the sensorimotor cortex of rats by cobalt implantation. A new in vivo superfusion method was employed which gives free movement to the animals and allows study over periods of days and weeks. Most amino acids...

journal_title：Brain research

authors： Dodd PR,Bradford HF

更新日期：1976-07-30 00:00:00

abstract：:In the present experiment we examined the effect of progesterone upon dopamine (DA) release induced by a direct infusion of unlabeled L-dihydroxyphenylalanine (L-DOPA) into the caudate nucleus of freely behaving rats. Ovariectomized rats were implanted with a push-pull cannula directed at the caudate nucleus and subje...

journal_title：Brain research

authors： Dluzen DE,Ramirez VD

更新日期：1989-08-07 00:00:00

abstract：:The effects of dexmedetomidine, a highly selective alpha(2)-adrenoceptor agonist, on extracellular dopamine (DA) concentrations in the nucleus accumbens of awake rats were collected via in vivo cerebral microdialysis and measured using HPLC with electrochemical detection. The administration of dexmedetomidine (DEX) at...

journal_title：Brain research

authors： Whittington RA,Virag L,Morishima HO,Vulliemoz Y

更新日期：2001-11-16 00:00:00

abstract：:Multiple-unit activity (MUA) in the agranular medial prefrontal cortex (PFC) was recorded in conscious rabbits during a classical conditioning procedure involving repeated pairings of a 4-s tone conditioned stimulus (CS) with eye shock. Prior to behavioral training, significant tone-evoked increases in prefrontal MUA ...

journal_title：Brain research

authors： Gibbs CM,Powell DA

更新日期：1988-02-23 00:00:00