Abstract：
:Concentrations of monoamines and metabolites and uric acid were measured in sequential 15-min microdialysis samples taken from the area of the supraoptic nucleus (SON) in 9 urethane-anaesthetized rats. A decrease in blood pressure of 40 mm Hg was induced by withdrawing 3-4 ml of blood from an indwelling jugular catheter. This decreased blood pressure was maintained for 30 min and produced a significant rise in the concentrations of noradrenaline (NA) and its metabolite 4-hydroxy-3-methoxyphenylethan-1,2-diol (MHPG) and also in 5-hydroxytryptamine (5-HT) and the purine metabolite uric acid (UA). When blood pressure was returned to normal by replacing the withdrawn blood, the concentrations of NA, MHPG, 5-HT and UA returned to pre-haemorrhage levels within 15 min. No significant changes in concentrations of dopamine and its metabolites were found, and in 7 control animals sampled 1.5-2 mm away from the SON, in the area of the olfactory tubercle, concentrations of NA, MHPG, 5-HT and UA were not significantly altered by haemorrhage-induced decreases in blood pressure.
journal_name
Brain Resjournal_title
Brain researchauthors
Kendrick KM,Leng Gdoi
10.1016/0006-8993(88)91016-5subject
Has Abstractpub_date
1988-02-09 00:00:00pages
402-6issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(88)91016-5journal_volume
440pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:As an approach to understanding why central neurons fail to regenerate, we have studied the response to proximal axotomy of transcallosal neurons of the cerebral cortex of the mouse. Anatomical studies have indicated only very slight regenerative responses by this population of cortical neurons. To further examine the...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00100-5
更新日期：1997-05-02 00:00:00
abstract：:Using mild heat shock of rat brain slices as a model for cellular insult, corticosteroid-mediated regulation of protein synthesis has been investigated. Following a single in vivo injection of rats with corticosterone or the Type II glucocorticoid receptor agonist, RU-28362, synthesis of a 28 kDa protein is elevated i...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01988-5
更新日期：1999-11-13 00:00:00
abstract：:The effects of estrus and prolonged estradiol benzoate (EB) treatment on estrogen receptor-like immunoreactivity (ER-LI) were studied in the female Brazilian opossum (monodelphis domestica) brain. In general, both estrus animals and EB treated animals had reduced ER-LI in specific brain regions when compared to ovarie...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90632-w
更新日期：1993-07-16 00:00:00
abstract：:Dopaminergic psychostimulants produce behavioral responses of greater magnitude with repeated, intermittent administration, than a single, acute dose, a phenomenon known as 'sensitization'. Alterations in regional neuronal activity produced by quinpirole, a D(2)/D(3) agonist, in quinpirole-naive and quinpirole-sensiti...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)04115-x
更新日期：2003-02-28 00:00:00
abstract：:The aim of the current study was to assess modality-specific brain oscillatory responses during cognitive processing. Brain oscillatory ERD/ERS responses of the 4- to 30-Hz EEG frequency bands were examined during lexical decision where the task is to identify whether the presented stimulus is a word or a pseudoword. ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.06.100
更新日期：2006-09-19 00:00:00
abstract：:Gonadotrophin-releasing hormone (GnRH) neurons do not express the leptin receptor (OB-R) in the medial preoptic area (MPOA) and the medial basal hypothalamus (MBH). We assessed whether the effect of leptin on the secretion of luteinizing hormone (LH), follicle stimulating hormone (FSH) and prolactin (PRL) in proestrus...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.02.001
更新日期：2015-04-16 00:00:00
abstract：:The electrical property of delayed K+ currents (IKD) was studied in pyramidal neurones freshly isolated from the rat hippocampal CA1 region. The IKD was separated pharmacologically from other membrane currents. Activation and inactivation processes of the IKD were highly voltage-dependent in the potential range betwee...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)91425-z
更新日期：1991-12-24 00:00:00
abstract：:Recent studies have demonstrated the neuroprotective properties of the novel imidazoquinoline benzodiazepine receptor partial agonist, PNU-101017, in the gerbil forebrain ischemia model. The compound effectively reduces delayed post-ischemic (5 min bilateral carotid occlusion) hippocampal CA1 neuronal degeneration eve...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00478-8
更新日期：1998-07-06 00:00:00
abstract：:Ion-sensitive microelectrodes were used to study the behavior of extracellular ions in rat sciatic nerve during and following activity. Nerve stimulation produced increases in [K+]o that were dependent upon the frequency and duration of stimulation; no change in extracellular pH occurred with stimulation. Increases in...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90666-j
更新日期：1991-06-21 00:00:00
abstract：:Intracellular transport of newly synthesized proteins through organelles in the perikarya of regenerating goldfish retinal ganglion cells was studied using electron microscopic autoradiography. Retinas were removed 14 or 30 days after optic tract cut or sham operation, pulse-labeled in [3H]proline-containing medium fo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90832-0
更新日期：1982-05-06 00:00:00
abstract：:The choroid plexus epithelium constitutes the structural basis of the blood-cerebrospinal fluid barrier. We previously demonstrated that Streptococcus suis (S. suis), a relevant cause of bacterial meningitis in pigs and humans, affects porcine choroid plexus epithelial cell (PCPEC) barrier function and integrity. We n...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.05.041
更新日期：2006-07-19 00:00:00
abstract：:The conduction velocity of frog ischiadic nerves incubated in vitro in osmolarities between 220 and 1000 mOsm decreased with the degree of fiber shrinkage. The latter (non-circularity factor) was determined from computer-assisted measurements in freeze-substituted or in chemically fixed fibers. Freeze-substituted norm...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90546-8
更新日期：1984-04-09 00:00:00
abstract：:The retina of the skate (Raja clavata, R. radiata and R. oscellata) was studied by autoradiography following intraocular injections or incubations with [3H]GABA, [3H]isoguvacine, [3H]glycine, [3H]dopamine or [3H]5-hydroxytryptamine. Fluorescence immunohistochemistry was also used to demonstrate the endogenous content,...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90972-7
更新日期：1984-03-19 00:00:00
abstract：:Hypothalamic control of thermoregulatory evaporation has been examined in hydrated and dehydrated cats exposed to warm ambient temperatures. Reduction in evaporative cooling during dehydration is associated with increased hypothalamic temperature. Local thermal stimulation of the hypothalamus indicates that the thermo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90120-7
更新日期：1981-02-09 00:00:00
abstract：:Dehydroepiandrosterone (DHEA) modulates neurogenesis, neuronal function, neuronal survival and metabolism, enhancing mitochondrial oxidative capacity. Glucose deprivation and hypometabolism have been implicated in the mechanisms that mediate neuronal damage in neurological disorders, and some studies have shown that t...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2016.05.014
更新日期：2016-08-01 00:00:00
abstract：:The effect of aging on delta opioid receptors was examined in the brains of guinea pigs aged 1, 6, 24 and 36 months. Quantitative autoradiography was used to monitor the concentrations of delta receptors in various anatomical regions at five rostro-caudal levels. delta opioid receptor populations were found to be rema...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91021-j
更新日期：1993-06-18 00:00:00
abstract：OBJECTIVE:The modern brain imaging studies in patients with eating disorders have shown that neurotransmitting regulation differs distinctly from control groups. These disturbances have involved serotonin and dopamine system can be inherited and conditioned by genes. The aim of this work has been the analysis of associ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.10.035
更新日期：2010-01-11 00:00:00
abstract：:The ability of membrane-associated peptidases from the brains of spontaneously hypertensive rats (SHRs) and normotensive Wistar-Kyoto (WKY) rats to metabolize iodinated angiotensin (125I-Ang II) and 125I-Ang III was compared. 125I-Ang II was metabolized to 125I-Ang III and other fragments exclusively by membrane-assoc...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90844-2
更新日期：1990-10-08 00:00:00
abstract：:Methionine (Met) enkephalin is detectable in rat hypothalamic and neurointermediate lobe (NIL) tissue extracts using a specific radioimmunoassay. Reversed-phase HPLC revealed that only the pentapeptide form was present in the extracts. Total amounts of Met-enkephalin in extracts containing the median eminence (ME), su...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90895-i
更新日期：1990-05-14 00:00:00
abstract：:The distribution of pituitary adenylate cyclase-activating polypeptide (PACAP) was examined in the tooth pulp. In rat and human tooth pulps, PACAP-immunoreactive (IR) nerve fibers were observed around blood vessels and in the subodontoblastic and odontoblastic layers. The predentine and dentine were devoid of such ner...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(03)02876-2
更新日期：2003-08-08 00:00:00
abstract：:The VIIIth cranial nerve projections in the hagfish, which has only one circular canal in the ear, were studied by transganglionic HRP transport. This nerve has two branches, the nervus utricularis (N. utr.) and the nervus saccularis (N. sac.), each with its own ganglion, the ganglion utriculare (G. utr.) and the gang...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91610-5
更新日期：1985-06-24 00:00:00
abstract：:This study evaluated the effect of stress during puberty on sexual motivation and the correlation between serum testosterone levels (T) and the absolute power of the theta electroencephalographic rhythms, recorded in the medial prefrontal cortex (mPFC) and basolateral amygdala (BLA) of adult male rats. Thirty males of...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2020.146937
更新日期：2020-10-15 00:00:00
abstract：:Previous findings from our laboratory demonstrated [125I]angiotensin II (AII) binding to plasma membranes from rat but not gerbil circumventricular organs (CVOs), the presumed location of brain receptors for angiotensin-induced dipsogenicity. Since members of both species drink to intracranially applied AII, a degrada...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90822-9
更新日期：1984-03-12 00:00:00
abstract：:An indirect method of immunocytochemistry showed that cholera toxin and its B-subunit served as specific neuronal surface markers in conjunction with monoclonal anti-cholera toxin and FITC labeled anti-mouse Fab. The cell types which get specifically stained in culture were peripheral neurons from dorsal root ganglion...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90305-5
更新日期：1982-06-24 00:00:00
abstract：:After transplantation of autologous sciatic nerve segments into the retina of adult hamsters for 1-2 months, retrograde labelling with horseradish peroxidase demonstrated a population of ganglion cells situated peripheral to the graft. If an additional lesion was placed between the insertion of the graft and the optic...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91203-5
更新日期：1986-07-02 00:00:00
abstract：:The subfornical organ, along with other regions of the lamina terminalis, may contain osmoreceptors and is likely to be a site of action of blood-borne angiotensin II. The neural pathways by which these stimuli lead to vasopressin secretion, have been suggested to extend from the subfornical organ to hypothalamic site...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90708-4
更新日期：1991-08-30 00:00:00
abstract：:10-fold higher doses in SW mice. Furthermore, cotreatment of 129/SvEv mice with morphine plus a low dose of naltrexone (ca. 0.1 microgram/kg) that markedly enhances and prolongs morphine's antinociceptive effects in SW mice did not enhance, and often attenuated6 h. The marked GM1-induced attenuation of morphine's anti...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)02446-4
更新日期：2000-02-21 00:00:00
abstract：:Using [3H]para-aminoclonidine, alpha 2 adrenergic binding sites have been mapped in the rat and human CNS using in vitro labeling autoradiographic techniques. In both the rat and human thoracic spinal cord, high densities of alpha 2 binding sites were associated with the substantia gelatinosa and the intermediolateral...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/0165-0173(84)90030-4
更新日期：1984-03-01 00:00:00
abstract：:A review of the available literature reveals that proliferation of ependyma occurs during embryological and early postnatal periods of development. Turnover, however, declines significantly during postnatal life and only low levels of residual activity persist into adulthood under normal conditions. In some regions of...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/0165-0173(85)90016-5
更新日期：1985-04-01 00:00:00
abstract：:Toluene diisocyanate (TDI) induces respiratory allergy in mammals. Using immunohistochemistry and in situ hybridization histochemistry, the present study examined effects of nasal mucosa sensitization by TDI on the immunoreactivity for substance P (SP) and calcitonin gene-related peptide (CGRP) and on the expression o...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90692-3
更新日期：1992-04-03 00:00:00
