Kindling causes changes in the composition of the astrocytic cytoskeleton.

abstract：:The study makes an attempt to find out the action of norepinephrine (NE) and phenoxybenzamine (PB), applied at medial preoptic area (mPOA), in altering the sleep-awake responses, in free moving rats, which has not yet been reported. Effects of application of NE during day and PB during night, at mPOA, on sleep-awake r...

journal_title：Brain research

authors： Mohan Kumar V,Datta S,Chhina GS,Gandhi N,Singh B

更新日期：1984-11-26 00:00:00

abstract：:Increased permeability of the brain-blood barrier (BBB) in the piriform cortex (PC) has been reported in various animal models of temporal lobe epilepsy. Since BBB disruption induced by epileptogenic insult has not fully clarified, we attempted to determine whether changes in BBB-related molecules are associated with ...

journal_title：Brain research

authors： Sheen SH,Kim JE,Ryu HJ,Yang Y,Choi KC,Kang TC

更新日期：2011-01-19 00:00:00

abstract：:The hippocampal granule cells receive major inputs via the perforant path from other limbic structures such as the amygdala (AM). In this study, we examined Sprague-Dawley (SD) and Wistar rats, the effect of bilateral destructions of the hippocampal granule cells on the process of AM kindling and kindled AM seizures a...

journal_title：Brain research

authors： Tsunoda K,Mori N,Osonoe M,Ariga K,Saitoh H,Kittaka H,Ogata S

更新日期：1995-09-11 00:00:00

abstract：:A significant fall in the number of GABA-immunoreactive cells in laminae I-III of the rat spinal cord occurred in the somatotopic area of projection of the sciatic nerve after nerve transection. The decrease started at 2 weeks post-neurectomy, and at 4 weeks ipsilateral mean cell numbers were approximately 72% of cont...

journal_title：Brain research

authors： Castro-Lopes JM,Tavares I,Coimbra A

更新日期：1993-08-27 00:00:00

abstract：:After spinal cord injury (SCI), the rapidly upregulated chondroitin sulfate proteoglycans (CSPGs), the prominent chemical constituents and main repulsive factors of the glial scar, play an important role in the extremely limited ability to regenerate in adult mammals. Although many methods to overcome the inhibition h...

journal_title：Brain research

authors： Zhou HX,Li XY,Li FY,Liu C,Liang ZP,Liu S,Zhang B,Wang TY,Chu TC,Lu L,Ning GZ,Kong XH,Feng SQ

更新日期：2014-10-24 00:00:00

abstract：:A decline in the magnitude of the summated responses evoked by taste solutions began about 1 h following IXth nerve transection. In 41 IXth nerves transected at different lengths we found a linear relationship between the length of the IXth nerve stump remaining attached to the tongue and the time for the taste respon...

journal_title：Brain research

authors： Oakley B,Jones LB,Hosley MA

更新日期：1980-07-21 00:00:00

abstract：:Previous work has shown that bilateral injection of as little as 10 microgram of cycloheximide (CHX) into the amygdala, but not into the internal capsule, caused a time-dependent disruption of long-term retention of passive avoidance training. Under these conditions, protein synthesis in the entire brain was inhibited...

journal_title：Brain research

authors： Kesner RP,Partlow LM,Bush LG,Berman RF

更新日期：1981-03-23 00:00:00

abstract：:We previously reported that glial fibrillary acidic protein (GFAP) levels increased significantly at 3 days after stab wounds, relative to sham-operated controls, reaching a maximum of 200% of control value at 5-7 days. They then fell to near-normal values by 21 days. To determine whether these protein changes correla...

journal_title：Brain research

authors： Hozumi I,Aquino DA,Norton WT

更新日期：1990-11-26 00:00:00

abstract：:Rapid skin indentations can produce strong tap-like sensations that contain little information about skin indentation depth. Although slower stimuli produce weaker sensations, subjects can more accurately identify how the position of the skin surface changes with respect to the deeper tissues. This dissociation betwee...

journal_title：Brain research

authors： Horch KW,Tuckett RP,Burgess PR

更新日期：1984-09-10 00:00:00

abstract：:A central component of Attention Deficit Hyperactivity Disorder (ADHD) is increased distractibility in response to visual and auditory stimuli, which is linked to the superior colliculus (SC). Furthermore, there is now mounting evidence of altered collicular functioning in ADHD and it is proposed that a hyper-responsi...

journal_title：Brain research

authors： Brace LR,Kraev I,Rostron CL,Stewart MG,Overton PG,Dommett EJ

更新日期：2015-12-10 00:00:00

abstract：:The protective activity of trimetazidine (TMZ) against cochlear neurotoxicity induced by intraperitoneal and intracochlear administration of kainic acid (KA) has been analyzed. The amplitude of the CAP N1 wave was significantly higher in KA rats pretreated with TMZ, independently of the administration route, than in t...

journal_title：Brain research

authors： Gil-Loyzaga P,Hernández E,Carricondo F,Simón F,Poch-Broto J

更新日期：1999-04-24 00:00:00

abstract：:Cerebral vascular density is correlated with metabolic demands, which increase in highly active brain areas. External inputs are an essential requirement in the modeling of the visual cortex. Experience-mediated development is very active during the first postnatal month, when congruous blood supply is needed. We stud...

journal_title：Brain research

authors： Argandoña EG,Lafuente JV

更新日期：2000-02-07 00:00:00

abstract：:Schwann cell is a cell type that forms myelin sheath and provides trophic supports for neuronal cells by producing neurotrophic factors such as neurotrophins and neurokines in both normal and traumatic situations. It was recently reported that after lesion of sciatic nerve, mRNA for cholinergic differentiation factor ...

journal_title：Brain research

authors： Matsuoka I,Nakane A,Kurihara K

更新日期：1997-11-21 00:00:00

abstract：:The understanding of sarcasm reflects a complex process, which involves recognizing the beliefs of the speaker. There is a clear association between deficits in mentalizing, which is the ability to understand other people's behavior in terms of their mental state, and the understanding of sarcasm in individuals with a...

journal_title：Brain research

authors： Uchiyama H,Seki A,Kageyama H,Saito DN,Koeda T,Ohno K,Sadato N

更新日期：2006-12-08 00:00:00

abstract：:We used double staining immunocytochemical techniques to determine whether nitric oxide (NO) and Fos immunoreactivity induced by noxious visceral stimulation were colocalized in the neurons of the supraspinal areas. We observed a considerable increase in Fos-positive neurons in many brain areas after noxious stimulati...

journal_title：Brain research

authors： Rodella L,Rezzani R,Agostini C,Bianchi R

更新日期：1999-07-10 00:00:00

abstract：:The retrorubral field (RRF) contains numerous dopaminergic neurons and projects to the parvicellular reticular formation (RFp) of the medullary and pontomedullary brainstem, where many premotor neurons project to the orofacial motor nuclei. To know how the amygdala affects the RRF-RFp pathway in the rat, we first exam...

journal_title：Brain research

authors： Tsumori T,Qin Y,Yokota S,Niu JG,Yasui Y

更新日期：2010-01-08 00:00:00

abstract：:The effect of a dihydropyridine Ca2+ antagonist, cilnidipine, on voltage-dependent Ca2+ channels was studied in acutely dissociated rat CA1 pyramidal neurons using the nystatin-perforated patch recording configuration under voltage-clamp conditions. Cilnidipine had no effect on low-voltage-activated (LVA) Ca2+ channel...

journal_title：Brain research

authors： Murai Y,Uneyama H,Ishibashi H,Takahama K,Akaike N

更新日期：2000-01-31 00:00:00

abstract：:We have developed a serum-free chemically defined medium which allows the obtainment of a primary culture highly enriched in ciliated ependymal cells. Serum was never used. Mechanically dissociated neonatal rat brain hemisphere cells were seeded on a fibronectin substratum. Culture medium was minimum Eagle's medium un...

journal_title：Brain research

authors： Weibel M,Pettmann B,Artault JC,Sensenbrenner M,Labourdette G

更新日期：1986-03-01 00:00:00

abstract：:The present study was undertaken to examine the differential effect of estrogen (E) on the expression of tyrosine hydroxylase (TH) in the substantia nigra compacta (SNc) and in two subdivisions of the ventral tegmental area in ovariectomized (ovx) and ovx plus estradiol benzoate (ovx+E)-treated female rats. Cell count...

journal_title：Brain research

authors： Zsarnovszky A,Scalise TJ,Horvath TL,Naftolin F

更新日期：2000-06-23 00:00:00

abstract：:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy CADASIL is caused by more than a hundred NOTCH3 mutations. Virtually all encoded mutant proteins contain an odd number of cysteines. As such, structural changes in NOTCH3 may be the primary molecular abnormality in CADASIL. Thus...

journal_title：Brain research

authors： Zhang X,Lee SJ,Young KZ,Josephson DA,Geschwind MD,Wang MM

更新日期：2014-10-02 00:00:00

abstract：:The binding of [3H]flunitrazepam and [3H]Ro5-4864 to crude homogenates of amygdala-kindled and 'yoked' control rat brains was evaluated in subjects sacrificed 60 days after the sixth generalized convulsion. Decreases in the Bmax for [3H]flunitrazepam binding to 'central-type' benzodiazepine receptors were observed in ...

journal_title：Brain research

authors： Burnham WM,Niznik HB,Okazaki MM,Kish SJ

更新日期：1983-11-21 00:00:00

abstract：:Choline supplementation of the maternal diet has long-term facilitative effects on spatial and temporal memory processes in the offspring. To further delineate the impact of early nutritional status on brain and behavior, we examined effects of prenatal-choline availability on hippocampal oscillatory frequency bands i...

journal_title：Brain research

authors： Cheng RK,Williams CL,Meck WH

更新日期：2008-10-27 00:00:00

abstract：:A large body of evidence shows that methamphetamine (METH) causes sustained damage to the brain in animal models and human METH users. In chronic users there are indications of cognitive and motor deficits. Striatal neuropeptides are in a position to modulate the neurochemical effects of METH and consequently striatal...

journal_title：Brain research

authors： Afanador L,Mexhitaj I,Diaz C,Ordonez D,Baker L,Angulo JA

更新日期：2013-05-13 00:00:00

abstract：:Few clinical or experimental studies have carried out systematic investigations of cutaneous and deep sensibility in areas with referred muscle pain. Therefore, no clear signs of increased or decreased psychophysical responses to various somatosensory stimuli are found in referred pain areas. In the present study, a t...

journal_title：Brain research

authors： Graven-Nielsen T,Arendt-Nielsen L,Svensson P,Jensen TS

更新日期：1997-01-02 00:00:00

abstract：:Synaptic responses evoked in phrenic motoneurones (PMNs) by stimulation of the superior laryngeal nerve (SLN) were analysed in anaesthetised cats. Stimulation of the SLN was followed by inhibition of ipsilateral phrenic nerve discharge with the latency of 9.5 +/- 2.3 ms (mean +/- S.D.) and hyperpolarizations of ipsila...

journal_title：Brain research

authors： Bellingham MC,Lipski J,Voss MD

更新日期：1989-05-08 00:00:00

abstract：:Our previous work has revealed increased nitric oxide (NO) production in the cochlear perilymph following noise stress. However, it is not clear if the increase of NO is related to iNOS and whether NO-related oxidative stress can cause vascular tissue damage. In this study, iNOS immunoreactivity, NO production, and re...

journal_title：Brain research

authors： Shi X,Nuttall AL

更新日期：2003-03-28 00:00:00

abstract：:The motoneurons innervating the orbicularis oculi muscle from a subgroup within the facial nucleus, called the intermediate facial subnucleus. This makes it possible to study afferents to these motoneurons by means of autoradiographical tracing techniques. Many different injections were made in the brainstem and dienc...

journal_title：Brain research

authors： Holstege G,van Ham JJ,Tan J

更新日期：1986-05-28 00:00:00

abstract：:The lateral geniculate nucleus (LGN) of a fetal rat was transplanted to the visual cortex (VC) of a neonatal rat. A current source-density analysis of field potentials and an intracellular study of neuronal responses were conducted in slice preparations by electrical stimulation of transplanted LGN and host VC. The re...

journal_title：Brain research

authors： Hamasaki T,Komatsu Y,Yamamoto N,Nakajima S,Hirakawa K,Toyama K

更新日期：1987-09-29 00:00:00

abstract：:Current and voltage responses elicited by increasing or decreasing the concentration of L-glutamate or its analog kainate around isolated cone horizontal cells were measured with patch pipettes using the whole cell recording configuration. Application of these photoreceptor transmitter agonists induced inward currents...

journal_title：Brain research

authors： Perlman I,Knapp AG,Dowling JE

更新日期：1989-05-15 00:00:00

abstract：:We examined the involvement of tumor necrosis factor (TNF)-alpha on glutamate-induced cytotoxicity in a differentiated neuronal cell line. In this study, we used nerve growth factor (NGF)-differentiated PC12h cells. Glutamate cytotoxicity was assessed using the MTS and TUNEL assays. To detect TNF-alpha levels in cultu...

journal_title：Brain research

authors： Kogo J,Takeba Y,Kumai T,Kitaoka Y,Matsumoto N,Ueno S,Kobayashi S

更新日期：2006-11-29 00:00:00