Electrophysiological study of synaptic connections between a transplanted lateral geniculate nucleus and the visual cortex of the host rat.

abstract：:Activation of microglia is a well-documented phenomenon associated with diverse pathological conditions of the central nervous system. In order to investigate the involvement of microglial cells in the neurotoxic action of the heavy metal compound trimethyltin, three-dimensional brain cell cultures were treated during...

journal_title：Brain research

authors： Monnet-Tschudi F,Zurich MG,Pithon E,van Melle G,Honegger P

更新日期：1995-08-28 00:00:00

abstract：:The acute effects of ethanol on the gamma-aminobutyric acid (GABA)-activated current were studied with the rat dorsal root ganglion neurons in primary culture using the whole-cell patch-clamp technique. GABA produced an inward chloride current, which was composed of an initial transient and a subsequent sustained phas...

journal_title：Brain research

authors： Nishio M,Narahashi T

更新日期：1990-06-04 00:00:00

abstract：:We investigated the influence of muramyl dipeptide (MDP), a cell wall component of Gram-positive bacteria, on cytokine-induced nitric oxide (NO) production in rat primary astrocytes. MDP alone did not induce NO release in astrocyte cultures. However, MDP increased astrocyte NO production and subsequent nitrite accumul...

journal_title：Brain research

authors： Trajkovic V,Samardzic T,Stosic-Grujicic S,Ramic Z,Mostarica Stojkovic M

更新日期：2000-11-10 00:00:00

abstract：:Lesions of the anterior hypothalamus-medial preoptic area (AH-MPOA) impair courtship and copulatory behavior in male Cnemidophorus inornatus, a sexually reproducing species of whiptail lizard, and male-like pseudosexual behaviors in C. uniparens, an all-female species. These results suggest that, since C. inornatus is...

journal_title：Brain research

authors： Kingston PA,Crews D

更新日期：1994-04-18 00:00:00

abstract：:The effects of hyperbaric oxygen have been studied on synaptic transmission in the hippocampal brain slice. Oxygen enhances both the prevolley and postsynaptic potential of extracellularly recorded responses following focal stimulation of afferent fiber bundles, but synaptic efficiency is reduced. It is suggested that...

journal_title：Brain research

authors： King GL,Parmentier JL

更新日期：1983-01-31 00:00:00

abstract：:Adenosine and its agonists exert a depressant effect on neuronal activity by interacting with the adenosine A1 receptor. There is now also evidence for electrophysiological effects mediated by adenosine receptors other than the A1 type, possibly A2 receptors. A1 and A2 receptor-induced changes in the electrical proper...

journal_title：Brain research

authors： Ameri A,Jurna I

更新日期：1991-04-12 00:00:00

abstract：:Several labeled neurotransmitter substances or precursors ( [3H]histamine, [3H]serotonin, and [3H]choline) were injected with pressure into the cell body of C2, an identified putative histaminergic neuron in the cerebral ganglion of Aplysia in order to study the selectivity of axonal transport. We examined transport o...

journal_title：Brain research

authors： Gotoh H,Schwartz JH

更新日期：1982-06-17 00:00:00

abstract：:Granule cell progenitors in the dentate gyrus of the hippocampal formation have the unusual capacity to be able to divide in the brains of adult rats and primates. The basal proliferation rate of granule cell progenitors in the adult rat is low compared with development, however, it is possible that this rate may beco...

journal_title：Brain research

authors： Gray WP,Sundstrom LE

更新日期：1998-04-20 00:00:00

abstract：:Endothelin (ET) is a small peptide that activates astrocyte proliferation, regulates proliferation and migration of embryonic neural precursor cells and stimulates glioblastoma growth. We found that in mouse brain, ET and its receptor B (ETRB) were highly expressed in the subependymal zone (SEZ), an adult neurogenic n...

journal_title：Brain research

authors： Castañeda MM,Cubilla MA,López-Vicchi MM,Suburo AM

更新日期：2010-03-19 00:00:00

abstract：:Mechanical hyperalgesia is an early symptom of diabetic neuropathy. To evaluate the mechanisms underlying this symptom, it was studied and compared in rat models of systemic and local hyperglycemia. Systemic hyperglycemia was induced by a single injection of streptozotocin (STZ, 50 mg/kg). Local hyperglycemia either i...

journal_title：Brain research

authors： Dobretsov M,Hastings SL,Romanovsky D,Stimers JR,Zhang JM

更新日期：2003-01-17 00:00:00

abstract：:Trophic effects of neurturin, a member of the glial cell line-derived neurotrophic factor-family, have been demonstrated on mesencephalic dopaminergic neurons, suggesting its therapeutic potential for Parkinson's disease. This study was designed to test the neuroprotective and regenerative effects of an intrastriatal ...

journal_title：Brain research

authors： Oiwa Y,Yoshimura R,Nakai K,Itakura T

更新日期：2002-08-30 00:00:00

abstract：:We evaluated the role of neuropeptide Y (NPY), a potent endogenous orexigenic signal, in the ventromedial hypothalamic (VMH) lesion-induced hyperphagia in rats. To produce hyperphagia and excessive weight gain, adult female rats received bilateral electrolytic or sham lesions in the VMH. Concurrently, a permanent intr...

journal_title：Brain research

authors： Dube MG,Kalra PS,Crowley WR,Kalra SP

更新日期：1995-09-04 00:00:00

abstract：:Phospholipid extracts from 48 intracranial tumors were analyzed using 31P NMR. Phospholipids commonly identified in the tumor spectra included phosphatidylglycerol (PG), phosphatidic acid (PA), diphosphatidylglycerol (DPG), uncharacterized phospholipid (U), ethanolamine plasmalogen (EPLAS), phosphatidylethanolamine (P...

journal_title：Brain research

authors： Merchant TE,van der Ven LT,Minsky BD,Diamantis PM,Delapaz R,Galicich J,Glonek T

更新日期：1994-06-27 00:00:00

abstract：:Photopic and scotopic spectral sensitivity of rhesus monkeys was determined before and after complete removal of the striate cortex. The monkeys were required to choose between a white and a series of monochromatic stimuli distributed throughout the visible spectrum. A modified method of limits was used to determine t...

journal_title：Brain research

authors： Leporé F,Cardu B,Rasmussen T,Malmo RB

更新日期：1975-08-08 00:00:00

abstract：:The effects of the intraventricular administration of aluminum chloride (AlCl3) on high affinity choline transport (HAChT) and norepinephrine concentration were examined in the hippocampus of the rat. Controlling for osmolarity and pH, the intraventricular administration of AlCl3 resulted in a dose-related reduction i...

journal_title：Brain research

authors： Zubenko GS,Hanin I

更新日期：1989-10-02 00:00:00

abstract：:The hypothesis that glutamate is the afferent transmitter in the acoustico-lateralis receptors was examined in Plotosus electroreceptors. JSTX , a spider toxin known to specifically block glutamate receptors, irreversibly abolished afferent impulse discharges induced by iontophoretically applied glutamate, whereas tho...

journal_title：Brain research

authors： Nagai T,Obara S,Kawai N

更新日期：1984-05-21 00:00:00

abstract：:Deacetylation is a rapid clearance mechanism for ocular melatonin. We have studied the distribution of retinal melatonin deacetylase activity among vertebrate classes. Exogenous radiolabeled melatonin is metabolized by ocular tissue prepared from the amphibian Xenopus laevis, the reptile Anolis carolinensis, the teleo...

journal_title：Brain research

authors： Grace MS,Cahill GM,Besharse JC

更新日期：1991-09-13 00:00:00

abstract：:One hour after long-term potentiation (LTP) in the intact hippocampus, a selective increase in protein F1 in vitro phosphorylation was observed in homogenate prepared from dorsal hippocampus. Protein F1 phosphorylation was directly related to the magnitude and persistence of potentiation. No other phosphoprotein studi...

journal_title：Brain research

authors： Lovinger DM,Colley PA,Akers RF,Nelson RB,Routtenberg A

更新日期：1986-12-10 00:00:00

abstract：:To determine the effects of nerve injury on Fos expression, temporal and spatial distributions of Fos-positive neurons in the trigeminal nucleus caudalis were examined after tissue injury for isolation of the infraorbital nerve as controls and transection of this nerve as well as noxious chemical stimulation by formal...

journal_title：Brain research

authors： Terayama R,Nagamatsu N,Ikeda T,Nakamura T,Rahman OI,Sakoda S,Shiba R,Nishimori T

更新日期：1997-09-12 00:00:00

abstract：:Autoradiographic techniques were used to test if positive modulators of AMPA-type glutamate receptors have regionally differentiated effects on ligand binding. Cyclothiazide, a drug with ten fold greater effects on 'flip' than 'flop' splice variants of the receptors, had unequal effects across the subdivisions of hipp...

journal_title：Brain research

authors： Kessler M,Mutneja MS,Rogers G,Lynch G

更新日期：1998-02-02 00:00:00

abstract：:Pretreatment with scopolamine, 3 mg/kg, prevented the acquisition of a passive avoidance task in rats. These amnesic effects of scopolamine could largely be overcome by treatment with 100 mg/kg of the nootropic drug piracetam. In order to identify the brain structures involved, the effects of these drugs on regional e...

journal_title：Brain research

authors： Piercey MF,Vogelsang GD,Franklin SR,Tang AH

更新日期：1987-10-20 00:00:00

abstract：:Corticotropin-releasing hormone (CRH) and vasopressin (AVP) participate in the endocrine, autonomic, immunological and behavioral response to stress. CRH and AVP receptors are found in hippocampus and anterior pituitary, where mineralocorticoid (MR) and glucocorticoid (GR) receptors are abundant. We investigated the p...

journal_title：Brain research

authors： Hügin-Flores ME,Steimer T,Schulz P,Vallotton MB,Aubert ML

更新日期：2003-06-27 00:00:00

abstract：:We describe a method to produce frog olfactory epithelium with a population of developmentally synchronized receptor cells suitable for electrophysiological studies. The epithelium is ablated with ZnSO4 and allowed to regenerate for 10 days. Generation of new cells is then blocked by continuous treatment with hydroxyu...

journal_title：Brain research

authors： Lidow MS,Gesteland RC,Shipley MT,Kleene SJ

更新日期：1987-02-01 00:00:00

abstract：:Active substance P binding sites were solubilized from rat brain membranes by treatment with 0.125% sodium glycodeoxycholate and 1 M NaCl. About 50% of the binding activity in membrane-bound binding sites was recovered in the solubilized fraction after centrifugation at 105,000 g for 1 h. [3H]Substance P absorbed exte...

journal_title：Brain research

authors： Maruyama M

更新日期：1986-04-02 00:00:00

abstract：:The understanding of sentences involves not only the retrieval of the meaning of single words, but the identification of the relation between a verb and its arguments. The way the brain manages to process word meaning and syntactic relations during language comprehension on-line still is a matter of debate. Here we re...

journal_title：Brain research

authors： Friederici AD,Weissenborn J

更新日期：2007-05-18 00:00:00

abstract：:The laminin-alpha2 chain is a component of brain capillary basement membranes and appears also to be present in neurons of rat, rabbit, pig and non-human primate brain as evidenced by immunohistochemistry. In the present study, we have further characterized this very distinct neuronal laminin-alpha2 chain-like immunor...

journal_title：Brain research

authors： Tian M,Hagg T,Denisova N,Knusel B,Engvall E,Jucker M

更新日期：1997-08-01 00:00:00

abstract：:Tetanization of commissural-CA1 input to the apical dendrites of the dorsal hippocampal CA1 area was found to produce a marked long-term potentiation of the field EPSP. Whereas by concurrent tetanization of the commissural pathway and medial septo-CA1 input, this potentiation was significantly reduced. Thus a negative...

journal_title：Brain research

authors： Xie XP

更新日期：1988-04-05 00:00:00

abstract：:Different groups of rats received three injections of either D-amphetamine (2.5 micrograms/0.5 microliters/side) or saline into the ventral tegmental area (VTA), one injection every third day. Two weeks following the last injection, dopamine (DA) neurotransmission in the nucleus accumbens (N. Acc.) was assessed with i...

journal_title：Brain research

authors： Vezina P

更新日期：1993-03-12 00:00:00

abstract：:Using a perifusion culture technique, the pattern of vasopressin release from the suprachiasmatic nucleus was studied in vitro under basal and stimulated conditions. Individual rat suprachiasmatic explants released vasopressin in a rhythmic fashion and these rhythms persisted with a circadian period for up to 4 cycles...

journal_title：Brain research

authors： Earnest DJ,Sladek CD

更新日期：1987-10-06 00:00:00

abstract：:The effects of glucagon like peptide-1 (GLP-1) on reflex swallowing were examined using anaesthetized rats. GLP-1 was injected into the dorsal vagal complex (DVC) using glass micropipettes. Swallowing was induced by repeated electrical stimulation of the central cut end of the superior laryngeal nerve (SLN) and was id...

journal_title：Brain research

authors： Kobashi M,Mizutani S,Fujita M,Mitoh Y,Shimatani Y,Matsuo R

更新日期：2017-09-15 00:00:00