当前位置： SCI文献检索 > BRAIN RESEARCH期刊下所有文献 > Responses of isolated white perch horizontal cells to changes in the concentration of photoreceptor transmitter agonists.

Responses of isolated white perch horizontal cells to changes in the concentration of photoreceptor transmitter agonists.

Abstract：

:Current and voltage responses elicited by increasing or decreasing the concentration of L-glutamate or its analog kainate around isolated cone horizontal cells were measured with patch pipettes using the whole cell recording configuration. Application of these photoreceptor transmitter agonists induced inward currents in voltage-clamp experiments (for negative holding potentials) and depolarizing responses in current-clamp experiments. Continuous exposure to either drug produced inward currents which were maintained for as long as superfusion with the drugs continued. Reducing the concentration of the agonists by pressure ejection of pulses of drug-free Ringer's solution onto the cells completely turned off the drug-induced currents. Under current-clamp conditions, pulses of control Ringer's elicited hyperpolarizing responses of large amplitude (40-80 mV). The data demonstrate the ability to simulate in vitro the horizontal cell's photoresponses and thus support the use of cultured cells as a model system for studying horizontal cell physiology and pharmacology.

journal_name

Brain Res

journal_title

Brain research

authors

Perlman I,Knapp AG,Dowling JE

doi

10.1016/0006-8993(89)90935-9

subject

Has Abstract

pub_date

1989-05-15 00:00:00

pages

16-25

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(89)90935-9

journal_volume

487

pub_type

杂志文章

相关文献

BRAIN RESEARCH文献大全
  • Multiple ways to the prior occurrence of an event: an electrophysiological dissociation of experimental and conceptually driven familiarity in recognition memory.

    abstract：:Recent research has shown that familiarity contributes to associative memory when the to-be-associated stimuli are unitized during encoding. However, the specific processes underlying familiarity-based recognition of unitized representations are still indefinite. In this study, we present electrophysiologically dissoc...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2010.08.089

    authors： Wiegand I,Bader R,Mecklinger A

    更新日期：2010-11-11 00:00:00

  • Glutamate as a CNS transmitter. I. Evaluation of glucose and glutamine as precursors for the synthesis of preferentially released glutamate.

    abstract：:Slices of the molecular layer of the dentate gyrus of the hippocampal formation were incubated with either [14C]glucose, [14C]pyruvate or 14C glutamine and the efflux of endogenous and radioactive glutamate was monitored under various conditions. After prelabeling with either [14C]glutamine or [14C]glucose elevation o...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(79)90306-8

    authors： Hamberger AC,Chiang GH,Nylén ES,Scheff SW,Cotman CW

    更新日期：1979-06-08 00:00:00

  • Surprisingly rich projection from locus coeruleus to the olfactory bulb in the rat.

    abstract：:The brainstem nucleus, locus coeruleus (LC), is the major, if not the sole, source of noradrenergic (NE) innervation of the telencephalon. It is generally held that LC neurons project diffusely to the entire neuroaxis and this had been the basis for theories that postulate 'general' functions (sleep, attention, learni...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(85)90537-2

    authors： Shipley MT,Halloran FJ,de la Torre J

    更新日期：1985-03-11 00:00:00

  • Chronic exposure to alcohol during development alters the membrane properties of cerebellar Purkinje neurons in culture.

    abstract：:The active and passive membrane properties of developing Purkinje neurons in control cultures and cultures chronically treated with 20 or 40 mM ethanol for 1 or 2 weeks were examined using whole-cell current-clamp techniques. The membrane properties were characterized by the features of the voltage responses evoked by...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(91)90707-3

    authors： Gruol DL

    更新日期：1991-08-30 00:00:00

  • Spread of scrapie agent to the central nervous system: study of a rat model.

    abstract：:Invasion of scrapie agent into the central nervous system (CNS) was studied in rats following intracerebral and peripheral inoculation, the latter by injection into intact or transected sciatic nerve. Comparison of sleep-wakefulness alterations, neuropathological features, and time lag of electroencephalographic and c...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(86)90048-x

    authors： Bassant MH,Baron H,Gumpel M,Cathala F,Court L

    更新日期：1986-09-24 00:00:00

  • Effects of exposure to an imprinting stimulus on the activity of enzymes involved in acetylcholine metabolism in chick brain.

    abstract：:One-day-old chicks were exposed for 60 min to either an imprinting stimulus or a dark-box. They were killed at 0, 1, 6 or 12 h after the end of this treatment, and the activities of acetylcholinesterase (AChE) and choline acetyltransferase (ChAc) assayed in the forebrain roof, forebrain base and midbrain. The activity...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(75)90271-1

    authors： Haywood J,Hambley J,Rose S

    更新日期：1975-07-11 00:00:00

  • Anatomical, physiological and biochemical studies on the cerebellum from mutant mice. III. Protein differences associated with the weaver, staggerer and nervous mutations.

    abstract：:The protein composition of subcellular fractions of the cerebella of normal and weaver, staggerer and nervous mutant mice and of X-irradiated rats are studied by polyacrylamide gel electrophoresis in sodium dodecyl sulphate. The patterns observed are compared with those of granular and Purkinje cells purified from rat...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(76)90800-3

    authors： Mallet J,Huchet M,Pougeois R,Changeux JP

    更新日期：1976-02-20 00:00:00

  • Identification of differentially expressed proteins in the spinal cord of neuropathic pain models with PKCgamma silence by proteomic analysis.

    abstract：:In order to elucidate the mechanisms that PKCγ regulates neuropathic pain (NP), and detect proteins that are associated with the function of PKCγ in NP, we exploited a chronic constriction injury (CCI)-induced neuropathic pain rat (CCI-NP rat) model in which PKCγ knockdown in the spinal cord was successfully carried o...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2011.12.046

    authors： Zou W,Zhan X,Li M,Song Z,Liu C,Peng F,Guo Q

    更新日期：2012-02-27 00:00:00

  • Effects of bicuculline on inspiratory activities in piglets.

    abstract：:Antagonism of the alpha receptor sub-type at gamma-aminobutyric acid (GABA) recognition sites in developing pigs was evaluated using the GABAA receptor antagonist bicuculline. The effect of bicuculline infusions was to produce an increase of phrenic and hypoglossal discharge amplitudes. This bicuculline-induced effect...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(94)90222-4

    authors： Steele AM,Siddiqi ZA,Sica AL

    更新日期：1994-07-04 00:00:00

  • Kinetic analysis of L-carnitine uptake by the choroid plexus.

    abstract：:Choroid plexuses from the lateral (LVCP) and fourth ventricles (FVCP) of rats or rabbits were incubated in artificial cerebrospinal fluid (CSF) containing 1 microM [14C]L-carnitine with various concentrations of L-carnitine ranging from 0.01 mM to 1.0 mM. The time course of 1 microM [14C]L-carnitine uptake by the chor...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(91)90188-2

    authors： Kim CS,Roe CR

    更新日期：1991-07-19 00:00:00

  • Protein tyrosine kinase and mitogen-activated protein kinase activation contribute to K(ATP) and K(ca) channel impairment after brain injury.

    abstract：:Previous studies have observed that pial artery dilation to activators of the ATP sensitive K (K(ATP)) and calcium sensitive K (K(ca)) channel was blunted following fluid percussion brain injury (FPI) in the piglet. In recent studies in the rat, protein tyrosine kinase (PTK) activation was observed to contribute to K(...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/s0006-8993(02)02703-8

    authors： Armstead WM

    更新日期：2002-07-12 00:00:00

  • The vascular response to nerve crush: relationship to Wallerian degeneration and regeneration.

    abstract：:The response of the endoneurial vasculature in rat sciatic nerve following crush injury was investigated by morphometric analysis of serial nerve transverse sections at the site of injury and in distal segments at 1, 2, 3, 6, and 9 weeks after injury. Quantitative analysis included determination of the number of vesse...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(93)90018-i

    authors： Podhajsky RJ,Myers RR

    更新日期：1993-09-24 00:00:00

  • Plasminogen activator is enriched in the synaptosomal plasma membranes.

    abstract：:The intracellular localization of the serine protease plasminogen activator was analyzed in homogenates of bovine brain cortex using differential fractionation procedures. The distribution of the enzyme was clearly different from that of cytosol and mitochondrial markers, and was similar to that of plasma membrane pro...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(82)91154-4

    authors： Zisapel N,Miskin R,Laudon M,Soreq H

    更新日期：1982-09-23 00:00:00

  • Habituation of the local cyclic GMP response during amygdaloid carbachol kindling in the rat.

    abstract：:Seizures kindled with amygdaloid carbachol injections are transynaptic, dependent on activation of a specific population of muscarinic receptors, and some components of their expression could be mediated by intracellular second messengers. We measured cyclic GMP and cyclic AMP concentrations in micropunch biopsies of ...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(86)90637-2

    authors： Wasterlain CG,Csiszar E,Fairchild MD

    更新日期：1986-11-12 00:00:00

  • Exposure to low concentrations of nicotine during cranial nerve development inhibits apoptosis and causes cellular hypertrophy in the ventral oculomotor nuclei of the chick embryo.

    abstract：:Maternal cigarette use during pregnancy is associated with increased incidence of neural impairments in offspring, but nicotine's unique contribution to any neuropathology remains unclear, and nicotine's neurodevelopmental effects assessed in animal models vary with concentration. During ontogenesis, the chick oculomo...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2003.11.070

    authors： Wielgus JJ,Corbin Downey L,Ewald KW,Hatley ME,Wilson KC,Yeilding RH

    更新日期：2004-03-12 00:00:00

  • Calretinin distribution in the octopus brain: an immunohistochemical and in situ hybridization histochemical analysis.

    abstract：:The distribution of calretinin containing neurons examined by in situ hybridization mapping was compared with that obtained by immunocytochemistry in the brain of octopus. Results revealed a close correspondence between the two types of investigations. Western blot analysis disclosed a 29 kDa protein immunostained wit...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2006.11.056

    authors： Altobelli GG,Cimini V

    更新日期：2007-02-09 00:00:00

  • Electrophysiological properties of spinally-projecting A5 noradrenergic neurons.

    abstract：:Spinally-projecting A5 neurons were studied with anatomical and electrophysiological techniques in the rat. A detailed study of the number and distribution of spinally-projecting catecholaminergic (CA) and non-catecholaminergic neurons present in a defined area of ventrolateral pontine reticular formation was performe...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(84)90206-3

    authors： Byrum CE,Stornetta R,Guyenet PG

    更新日期：1984-06-11 00:00:00

  • Evidence for clonidine presynaptically modulating amino acid release in the rostral ventral medulla: role in hypertension.

    abstract：:Reports suggested that the predominant site of action for the antihypertensive effects of clonidine is the rostral ventrolateral medulla (RVL), the presumed tonic vasomotor center. This study examined whether clonidine directly interacts with nerve terminal alpha 2-adrenergic receptors in the RVL to inhibit the releas...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(90)90355-f

    authors： Tingley FD 3rd,Arnerić SP

    更新日期：1990-12-24 00:00:00

  • Are the dorsal noradrenergic bundle projections from the locus coeruleus important for neocortical or hippocampal activation?

    abstract：:Three different methods were used to examine the importance of the dorsal noradrenergic bundle projections from the locus coeruleus (LC) in activation of the neocortex and hippocampus in freely moving rats. (1) After cerebral norepinephrine (NE) was depleted by systemic neonatal injections of 6-hydroxydopamine (6-OHDA...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(77)90785-5

    authors： Robinson TE,Vanderwolf CH,Pappas BA

    更新日期：1977-12-09 00:00:00

  • Intraischemic hypothermia during pretreatment with sublethal ischemia reduces the induction of ischemic tolerance in the gerbil hippocampus.

    abstract：:We examined whether mild brain hypothermia during pretreatment with sublethal 2-min ischemia affected the tolerance to subsequent lethal 5-min ischemia. The neuronal densities in the hippocampal CA1 sector of gerbils preconditioned at mild brain hypothermia (32% of normal) were significantly lower than those in gerbil...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/s0006-8993(96)01139-0

    authors： Wada K,Miyazawa T,Katoh H,Nomura N,Yano A,Shima K,Chigasaki H

    更新日期：1997-01-23 00:00:00

  • Effect of LPS on the permeability of the blood-brain barrier to insulin.

    abstract：:Insulin has emerged as an important neuropeptide. Central actions of insulin appear to oppose those in the periphery. Insulin is transported across the blood-brain barrier (BBB) by a saturable transport system. The permeability of the BBB to insulin is altered by various events, but no studies exist that have examined...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/s0006-8993(00)03247-9

    authors： Xaio H,Banks WA,Niehoff ML,Morley JE

    更新日期：2001-03-30 00:00:00

  • Histamine H1 receptors in UC-11MG astrocytes and their regulation of cytoplasmic Ca2+.

    abstract：:Experiments were carried out on UC-11MG human astrocytoma cells, a continuous cell line that expresses a broad range of the biochemical and electrophysiological properties found in well-differentiated astrocytes. Because of a number of recent reports that astrocytes may express receptors for a variety of neuro-active ...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(92)91676-6

    authors： Lucherini MJ,Gruenstein E

    更新日期：1992-10-02 00:00:00

  • Targeting RPTPσ with lentiviral shRNA promotes neurites outgrowth of cortical neurons and improves functional recovery in a rat spinal cord contusion model.

    abstract：:After spinal cord injury (SCI), the rapidly upregulated chondroitin sulfate proteoglycans (CSPGs), the prominent chemical constituents and main repulsive factors of the glial scar, play an important role in the extremely limited ability to regenerate in adult mammals. Although many methods to overcome the inhibition h...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2014.08.048

    authors： Zhou HX,Li XY,Li FY,Liu C,Liang ZP,Liu S,Zhang B,Wang TY,Chu TC,Lu L,Ning GZ,Kong XH,Feng SQ

    更新日期：2014-10-24 00:00:00

  • Glucocorticoid effects on Fos immunoreactivity and NADPH-diaphorase histochemical staining following spinal cord injury.

    abstract：:Glucocorticoids (GC) provide neuroprotection and early recovery after spinal cord injury (SCI). While several mechanisms were proposed to account for these effects, limited information exists regarding GC actions in sensory areas of the spinal cord. Presently, we studied the time course of Fos expression, and reduced ...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/s0006-8993(01)02717-2

    authors： González S,Labombarda F,Gonzalez Deniselle MC,Saravia FE,Roig P,De Nicola AF

    更新日期：2001-09-07 00:00:00

  • Respiratory responses induced by blockades of GABA and glycine receptors within the Bötzinger complex and the pre-Bötzinger complex of the rabbit.

    abstract：:The respiratory role of GABA(A), GABA(B) and glycine receptors within the Bötzinger complex (BötC) and the pre-Bötzinger complex (preBötC) was investigated in alpha-chloralose-urethane anesthetized, vagotomized, paralysed and artificially ventilated rabbits by using bilateral microinjections (30-50 nl) of GABA and gly...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2010.05.032

    authors： Bongianni F,Mutolo D,Cinelli E,Pantaleo T

    更新日期：2010-07-16 00:00:00

  • Is there a reciprocal connection between the red nucleus and the interposed cerebellar nuclei? Conclusions based on observations of anterograde and retrograde transport of peroxidase-labelled lectin in the same animal.

    abstract：:The rubrointerposital projection was studied in cats where wheat germ agglutinin-horseradish peroxidase (WGA-HRP) was implanted in various parts of the interposed nuclei. No retrogradely labelled rubral cells were observed following implantations in the posterior interposed nucleus, and only very few such cells were i...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(86)91370-3

    authors： Walberg F,Dietrichs E

    更新日期：1986-11-05 00:00:00

  • Glucagon like peptide-1 (7-36) amide (GLP-1) nerve terminals densely innervate corticotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus.

    abstract：:Glucagon like peptide-1 (7-36) amide (GLP-1), a potent regulator of glucose homeostasis, is also produced in the central nervous system and has been implicated in the control of hypothalamic-pituitary function and food intake. GLP-1 immunoreactive (IR) fibers and terminals are widely distributed in the septum, hypotha...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/s0006-8993(03)03117-2

    authors： Sarkar S,Fekete C,Légrádi G,Lechan RM

    更新日期：2003-09-26 00:00:00

  • Conditioned taste aversion and latent inhibition following extensive taste preexposure in rats with insular cortex lesions.

    abstract：:Lesions of the insular cortex (IC) attenuate acquisition of conditioned taste aversions (CTAs). We have suggested that this impairment is the expected consequence of a failure of IC-lesioned (ICX) rats to recognize unfamiliar taste stimuli as novel. That is, ICX rats treat novel taste stimuli as if they are familiar a...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/j.brainres.2008.12.058

    authors： Roman C,Lin JY,Reilly S

    更新日期：2009-03-09 00:00:00

  • Dorsal raphe cells with collateral projections to the caudate-putamen and substantia nigra: a fluorescent retrograde double labeling study in the rat.

    abstract：:The relationship between the dorsal raphe neurons projecting to the caudate-putamen and those projecting to the substantia nigra was investigated using a fluorescent retrograde double labeling technique in the rat. The majority of the dorsal raphe neurons projecting to the substantia nigra were found to project also t...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(80)90250-4

    authors： van der Kooy D,Hattori T

    更新日期：1980-03-17 00:00:00

  • Some transforming growth factor-alpha connections and their colocalization with enkephalin in the rat central nervous system.

    abstract：:Transforming growth factor alpha (TGF alpha) has been immunocytochemically localized in neuronal perikarya throughout the adult rat central nervous system (CNS). In order to determine if any TGF alpha-immunoreactive (TGF alpha-I) cell bodies have long axonal projections, indirect immunofluorescence was used in combina...

    journal_title：Brain research

    pub_type： 杂志文章

    doi：10.1016/0006-8993(87)91317-5

    authors： Code RA,Seroogy KB,Fallon JH

    更新日期：1987-09-22 00:00:00