Abstract：
:Invasion of scrapie agent into the central nervous system (CNS) was studied in rats following intracerebral and peripheral inoculation, the latter by injection into intact or transected sciatic nerve. Comparison of sleep-wakefulness alterations, neuropathological features, and time lag of electroencephalographic and clinical signs in the 3 groups suggests that hematogenous spread of infection to the CNS may predominate over neural transport, and that peripheral inoculation may closely approximate natural infection.
journal_name
Brain Resjournal_title
Brain researchauthors
Bassant MH,Baron H,Gumpel M,Cathala F,Court Ldoi
10.1016/0006-8993(86)90048-xsubject
Has Abstractpub_date
1986-09-24 00:00:00pages
397-401issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(86)90048-Xjournal_volume
383pub_type
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