Abstract：
:Vasopressin generates a voltage-gated, sodium-dependent current in facial motoneurons in brainstem slices. Reducing the extracellular calcium concentration from 2 to 0.01 mM caused a 30 to 120% increase in the amplitude of this current. Lowering extracellular magnesium also enhanced it, but less efficiently. In the physiological solution, the response of facial neurons to vasopressin is thus partially blocked. Increasing extracellular calcium was without effect. Current-voltage curves indicate that the vasopressin current reversed at around 0 mV and suggest that the low-calcium-induced potentiation was due to an attenuation of the region of negative slope conductance.
journal_name
Brain Resjournal_title
Brain researchauthors
Alberi S,Dubois-Dauphin M,Dreifuss JJ,Raggenbass Mdoi
10.1016/0006-8993(93)90097-7subject
Has Abstractpub_date
1993-10-08 00:00:00pages
326-30issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(93)90097-7journal_volume
624pub_type
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