Abstract:
:The supracommissural ventral telencephalon and the medial preoptic area have been shown to play important roles in the sexual behavior of himé salmon (landlocked red salmon, Oncorhynchus nerka). In the present study, the sites of neurons projecting to these regions were examined by means of the retrograde horseradish peroxidase (HRP) tracing method. The morphology of neurons in these sites of origin was also studied by means of the Golgi method. The nucleus preopticus periventricularis and the rostral part of nucleus preopticus (NPP-rNPO) received bilateral projections from the middle parts of the area ventralis telencephali pars ventralis (Vv) and the area ventralis telencephali pars dorsalis (Vd), NPP and lateral part of the preoptic area (LPOA), ipsilateral projections from the caudal part of Vv, nucleus anterioris periventricularis (NAPv), nucleus ventromedialis thalami (NVM) at the level of the posterior commissure, nucleus lateralis tuberis pars medialis (NLTm), nucleus anterior tuberis (NAT), nucleus saccus vasculosus (NSV), nucleus recessus posterioris (NRP) and midbrain tegmentum (TG), and a projection from the nucleus posterior tuberis (NPT), which is situated on the midline of the brain. The area ventralis telencephali pars supracommissuralis and neighboring caudal ventral telencephalon (Vs-cV) received ipsilateral projections from almost all parts of the Vv, the middle and caudal parts of Vd, almost all parts of the NNP, the NPO at the level between the habenula and the posterior commissure, and the rostral part of the nucleus dorsomedialis thalami (NDM). The Vs-cV also received a projection from NPT. These findings seem to give anatomical bases for understanding the neural mechanisms involved in sexual behavior as well as neuroendocrine functions.
journal_name
Brain Resjournal_title
Brain researchauthors
Shiga T,Oka Y,Satou M,Okumoto N,Ueda Kdoi
10.1016/0006-8993(85)91286-7subject
Has Abstractpub_date
1985-12-30 00:00:00pages
162-77issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(85)91286-7journal_volume
361pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::Immunohistochemical localization of brain-derived neurotrophic factor (BDNF) in the monkey brain was investigated using a polyclonal anti-BDNF antibody produced in our laboratory. The antibody recognized a single band in monkey brain homogenates, and the estimated molecular weight was approximately 14 kDa, which corre...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)01082-3
更新日期:1999-03-13 00:00:00
abstract::An in vitro model was used to study the cytokinetics of astroglial cells derived from neonatal rat cerebellum. Confluent monolayers of astrocytes (85% astroglial as assessed by GFAP immunoreactivity) were subcultured at low cell density and after 2-3 days growth were rendered quiescent by shifting them to low serum me...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)91485-0
更新日期:1988-01-26 00:00:00
abstract::5-Hydroxytryptamine (5-HT) has been shown to activate the hypothalamo-pituitary-adrenal axis, possibly by a direct action on hypothalamic CRF synthesis and release. In order to study the mechanisms involved in this effect, foetal hypothalamic cells were cultured and corticotropin-releasing factor-41 (CRF) release was ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)90826-u
更新日期:1992-03-06 00:00:00
abstract::Male rats were dehydrated for 22 h and then given 4 h intracerebroventricular (i.c.v.) infusions which commenced 2 h prior to the beginning of a 2-h fluid access period. I.c.v. infusion of iso-osmotic 0.27 M mannitol-CSF more than halved the amount of water normally drunk by dehydrated rats during the fluid access per...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)91437-5
更新日期:1987-05-26 00:00:00
abstract::A motor disorder similar to idiopathic Parkinson's Disease develops in rhesus monkeys after several daily repeated doses of N-methyl-4-phenyl, 1,2,3,6-tetrahydropyridine (MPTP). The concentrations of peptides derived from proenkephalin A, proenkephalin B, substance P and somatostatin were measured by specific radioimm...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)90133-1
更新日期:1984-11-26 00:00:00
abstract::There are different kinds of visuomotor learnings. One of the most studied is error-based learning where the information about the sign and magnitude of the error is used to update the motor commands. However, there are other instances where subjects show visuomotor learning even if the use of error sign and magnitude...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2015.05.022
更新日期:2015-08-27 00:00:00
abstract::Systemic effects of anesthesia on the dynamics of the apnea-induced Blood Oxygen Level Dependent (BOLD) signal is still not clear. In the present study, the dynamics of the fMRI-BOLD signal and blood flow using laser Doppler flowmetry (LDF) was studied in rats in response to apnea. Two anesthetics namely pentobarbital...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2004.02.076
更新日期:2004-06-18 00:00:00
abstract::Regulation of tyrosine hydroxylase (TH) by second messenger pathway activators was examined in rat olfactory bulb cell cultures. The number of TH-immunoreactive neurons was increased 2-3-fold by 36 h treatments with forskolin (Fsk, 10(-6) M) or phorbol myristate acetate (PMA, 10(-7) M), but was not significantly incre...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(09)90015-4
更新日期:1994-09-26 00:00:00
abstract::It has been demonstrated previously that kappa opioid receptor agonists, such as dynorphin, inhibit oxytocin secretion in the rat. To determine whether kappa agonists act directly on oxytocin-containing magnocellular neurons to inhibit hormone secretion, we utilized immunofluorescence to examine the cellular localizat...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)02154-0
更新日期:2001-04-13 00:00:00
abstract::The effects of induced L9 activity on gill motor neuron L7's ability to elicit a gill withdrawal response were studied. It was found that L9 was a modulator of L7's effectiveness to elicit gill movements. Following L9 activity, L7's ability to elicit a gill withdrawal response was significantly potentiated by up to 24...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90350-0
更新日期:1979-03-16 00:00:00
abstract::Afferents from the nucleus reticularis thalami (RT) to the thalamic ventrobasal complex were studied in the rat by looking for degenerating terminals after selective neurotoxic lesion of RT using injections of kainic acid. Several lines of evidence are presented indicating that RT afferents terminate in the VB by F ty...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)90607-8
更新日期:1983-07-04 00:00:00
abstract::Rat hippocampal slices were perfused with epidermal growth factor (EGF) at a concentration of 10(-8) M. EGF is a well known mitogen which exhibits neurotrophic action on neurons of the CNS. During extra- and intracellular recordings in the pyramidal cell body layer of the CA1-region no influence of EGF on evoked poten...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90380-6
更新日期:1989-04-10 00:00:00
abstract::The ability to adapt a variety of motor acts to compensate for persistent natural or artificially induced errors in movement accuracy requires the cerebellum. For adaptation of the rapid shifts in the direction of gaze called saccades, the oculomotor vermis (OMV) of the cerebellum must be intact. We disrupted the neur...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.05.027
更新日期:2011-07-15 00:00:00
abstract::Spontaneous hippocampal EEG activity and evoked field potentials were investigated in intact rats and in animals with fetal hippocampal grafts. Pieces of hippocampal grafts, derived from 15- to 16-day-old fetuses, were used to prepare cell suspensions and grafted directly into the intact hippocampus. Control animals r...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90168-u
更新日期:1991-07-19 00:00:00
abstract::Glioblastoma multiform is the most common malignant primary brain tumor in adults, but there remains no effective therapeutic approach. 2-methoxyestradiol (2-ME), which is a naturally occurring metabolite of 17beta-estradiol, was shown to enhance radiotherapeutic effect in certain tumors; however, whether 2-ME can als...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.07.092
更新日期:2007-12-14 00:00:00
abstract::The multidrug resistance gene (Abcb1) protein product, phosphoglycoprotein (P-gp) is expressed on the luminal surface of capillary endothelial cells of the adult blood-brain barrier (bbb). P-gp is critical for neuroprotection as it actively pumps substrates back into the capillary lumen. The fetal brain represents a p...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.08.016
更新日期:2010-10-21 00:00:00
abstract::The uptake and efflux of 36Cl in the lateral ventricle choroid plexus of 1-7-week-old rats were measured to determine if Cl transport changed with age and if such transport responded to inhibitors of CSF secretion and ion transport. The steady-state (30 min) Cl uptakes were 148 +/- 9.4 nmol.mg-1 dry weight at 1 week a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)90076-y
更新日期:1993-10-08 00:00:00
abstract::The presence of corticotropin releasing factor (CRF)-immunoreactive nerve fibers and cell bodies in the spinal cord is demonstrated. Immunopositive fibers were found in the lateral column of the white matter, in laminae I, V-VII, X, and in the intermediolateral column of the spinal cord. Complete transection of the sp...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)91001-6
更新日期:1983-09-26 00:00:00
abstract::Spinal muscular atrophy is caused by deletions or mutations in the SMN1 gene that result in reduced expression of the SMN protein. The SMN protein is an essential molecular chaperone that is required for the biogenesis of multiple ribonucleoprotein (RNP) complexes including spliceosomal small nuclear RNPs (snRNPs). Re...
journal_title:Brain research
pub_type: 杂志文章,评审
doi:10.1016/j.brainres.2018.02.022
更新日期:2018-08-15 00:00:00
abstract::Nicergoline, a drug used for the treatment of Alzheimer's disease and other types of dementia, was tested for its ability to protect neurons against beta-amyloid toxicity. Pure cultures of rat cortical neurons were challenged with a toxic fragment of beta-amyloid peptide (betaAP(25-35)) and toxicity was assessed after...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.04.004
更新日期:2005-06-14 00:00:00
abstract::Serotonin (5-HT), dopamine (DA) and noradrenaline (NE) play important roles in brain postnatal maturation. Therefore, deficits in brain availability of biogenic amines during critical developmental phases might underlie neurodevelopmental disturbances associated with cognitive impairment. To test this hypothesis we ev...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2008.04.006
更新日期:2008-06-27 00:00:00
abstract::The effect of 4-aminopyridine (4-AP) on the release of labeled transmitters in mouse brain synaptosomes was studied in a superfusion system. 4-AP at microM concentrations notably stimulated the spontaneous release of labeled GABA and glutamate, and of acetylcholine (ACh) derived from tritiated choline. No effects on t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90423-1
更新日期:1982-11-04 00:00:00
abstract::These experiments examined the effects, on retention, of posttraining intra-amygdala administration of norepinephrine (NE), and propranolol. Rats were trained on a one-trial step-through inhibitory avoidance task and tested for retention 24 h later. Injections were administered bilaterally (1.0 microliter/injection) t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)91049-8
更新日期:1986-03-12 00:00:00
abstract::A procedure is described which allows for the selective and non-injectional staining of the three-dimensional microvasculatory bed (MVB) in thick sections (60-140 microm) of formalin-fixed brain tissue of white rats Rattus norvegicus. This histochemical method detects ATPase activity and takes place between pH 10.5 an...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.11.059
更新日期:2006-01-27 00:00:00
abstract::The dopamine-releasing and depleting substance amphetamine (AMPH) can make cortical neurons susceptible to damage, and the prevention of hyperthermia, seizures and stroke is thought to block these effects. Here we report a 2-day AMPH treatment paradigm which affected only interneurons in three cortical regions with av...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(02)03439-x
更新日期:2002-12-20 00:00:00
abstract::Gonadal steroids are thought to act by activation of the genome following cytoplasmic binding, translocation of the hormone--receptor complex to the nucleus and chromatin binding at specific acceptor sites. This study examined the kinetics of chromatin binding of estradiol by hypothalamic and cortical cells of adult g...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(78)90138-5
更新日期:1978-08-18 00:00:00
abstract::The astrocyte-derived protein S100B stimulates production of inducible nitric oxide synthase and nitric oxide (NO) in astrocytes [Hu et al., 1996, J. Biol. Chem. 271:2543], but its effect on microglia is not known. In addition, S100B's ability to modulate the activity of other glial activating agents has not been defi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)02251-9
更新日期:2000-01-17 00:00:00
abstract::Unlike the basal ganglia input from the midline and intralaminar nuclei, the origin and prominence of striatal projections arising in the lateral thalamus varies considerably among mammals being most restricted in the opossum and monkey, most extensive in the rat. To get further insight into the evolution of thalamo-s...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.04.125
更新日期:2006-07-19 00:00:00
abstract::Glycogen synthase kinase (GSK)-3beta and extracellular signal-regulated kinase (ERK) regulate several cellular signaling pathways in common, including embryonic development, cell differentiation and apoptosis. In this study, we investigated whether GSK-3beta inhibition is involved in ERK activation, which affects the ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.10.018
更新日期:2007-12-01 00:00:00
abstract::The distribution of neurocalcin-immunoreactive (NC-ir) primary sensory neurons was examined in the trigeminal ganglion (TG), mesencephalic trigeminal tract nucleus (Mes5) and intraoral structures. NC-ir primary sensory neurons were located in the TG but not the Mes5. The coexpression study demonstrated that virtually ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02175-2
更新日期:2000-05-02 00:00:00