Sleep-awake responses elicited from medial preoptic area on application of norepinephrine and phenoxybenzamine in free moving rats.

Abstract:

:The study makes an attempt to find out the action of norepinephrine (NE) and phenoxybenzamine (PB), applied at medial preoptic area (mPOA), in altering the sleep-awake responses, in free moving rats, which has not yet been reported. Effects of application of NE during day and PB during night, at mPOA, on sleep-awake responses, were compared with application of saline during identical periods. Application of NE produced arousal, whereas, PB produced the opposite effect. The findings are suggestive of the involvement of NE terminals at mPOA in normal arousal.

journal_name

Brain Res

journal_title

Brain research

authors

Mohan Kumar V,Datta S,Chhina GS,Gandhi N,Singh B

doi

10.1016/0006-8993(84)90125-2

subject

Has Abstract

pub_date

1984-11-26 00:00:00

pages

322-5

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(84)90125-2

journal_volume

322

pub_type

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