Morphologic and autoradiographic evidence for a laminated pretectal olivary nucleus in the squirrel monkey.

abstract：:The current study explored the effects of prolonged antidepressant treatment on mRNA levels of two nuclear receptors in specific brain regions of an animal model of depression, the Wistar-Kyoto (WKY) rat. Both nuclear receptors have been implicated in the development or treatment of depression. The expression of nucle...

journal_title：Brain research

authors： Schaffer DJ,Tunc-Ozcan E,Shukla PK,Volenec A,Redei EE

更新日期：2010-11-29 00:00:00

abstract：:Using a double-labelling procedure, morphological relationships existing between dopaminergic and indoleaminergic neuronal systems in the rat brain were investigated. First, thanks to a tryptamine (T) antiserum, we visualized this indoleamine in all mesencephalic regions and showed that the T-immunoreactivity (IR) see...

journal_title：Brain research

authors： Dabadie H,Mons N,Geffard M

更新日期：1990-03-26 00:00:00

abstract：:Rab3A is a small GTP-binding synaptic vesicle protein, shown to dissociate from synaptic vesicle membranes upon depolarization-induced exocytosis. Using an antiserum raised against rab3A, we found that the antigen was localized to the neuropil of specific brain regions, but was not present in major fiber tracts or mos...

journal_title：Brain research

authors： Moya KL,Tavitian B,Zahraoui A,Tavitian A

更新日期：1992-09-11 00:00:00

abstract：:Neuropathic pain remains a major complication of various forms of injury to peripheral nerves in humans. Recently, 2 models of peripheral mononeuropathy in the rat have been described which closely resemble the human condition. Bennett and Xie3 described one model induced by the placement of 4 loose ligatures around t...

journal_title：Brain research

authors： Dougherty PM,Garrison CJ,Carlton SM

更新日期：1992-01-20 00:00:00

abstract：:Administration of methamphetamine (15 mg/kg) to adrenalectomized rats significantly decreased hippocampal type I and II corticosteroid receptors as well as type II receptors in the striatum. Type II receptors in the frontal cortex and hypothalamus were unaffected by methamphetamine administration. Pretreatment with MK...

journal_title：Brain research

authors： Lowy MT

更新日期：1990-11-19 00:00:00

abstract：:Cortical sensory neurons synchronize their activity at multiple frequency bands after an external stimulation. In the somatosensory cortical areas, previous reports describe more discrete and somatotopically specific neural synchronization at the gamma band. Therefore, an efficient gamma synchronization of the neurons...

journal_title：Brain research

authors： Tecchio F,Babiloni C,Zappasodi F,Vecchio F,Pizzella V,Romani GL,Rossini PM

更新日期：2003-10-03 00:00:00

abstract：:Immunohistochemical staining with mouse monoclonal antibody R24 recognizing the ganglioside GD3 was used to study the distribution of GD3 in the human brain. Positive staining was primarily found in the surrounding neuropil of many neuronal groups in the brainstem and spinal cord, cerebellum, retina and dentate gyrus ...

journal_title：Brain research

authors： Graus F,Cordon-Cardo C,Houghton AN,Melamed MR,Old LJ

更新日期：1984-12-17 00:00:00

abstract：:The dependence of the carotid chemosensory response to hypoxia on metabolic substrate and the hypothesis that lactic acidosis is essential for O2 chemoreception were tested. Effects of 3 types of substrate (glucose, glutamate and a mixture of amino acids) on the response to hypoxia (perfusate flow interruption) were m...

journal_title：Brain research

authors： Spergel D,Lahiri S,Wilson DF

更新日期：1992-11-20 00:00:00

abstract：:Nitric oxide (NO) production in the sensory neurons of the rad nodose ganglion was studied by examining the distribuiotn of NO synthase (NOS) by use of NADPH diaphorase (NADPHD) histochemistry and immunohistochemistry ofr the presence of isoformes of NOS: neuronal (nNOS), endothelial (eNOS) and the inducible isoform (...

journal_title：Brain research

authors： Yamamoto Y,Henrich M,Snipes RL,Kummer W

更新日期：2003-01-24 00:00:00

abstract：:The main purpose of the present study was to determine whether specific lymphokines may be neurotrophic, by testing their effects on the survival of hippocampal neuronal cultures. Previous studies have shown that a variety of interleukins may be neurotrophic or neurotoxic, depending upon the culture conditions, as wel...

journal_title：Brain research

authors： Araujo DM,Cotman CW

更新日期：1993-01-08 00:00:00

abstract：:The distinction between neural mechanisms of explicit and implicit expressions of memory has been well studied at the retrieval stage, but less at encoding. In addition, dissociations obtained in many studies are complicated by methodological difficulties in obtaining process-pure measures of different types of memory...

journal_title：Brain research

authors： Meng Y,Ye X,Gonsalves BD

更新日期：2014-10-17 00:00:00

abstract：:The present study was designed to examine the trophic effect of sympathetic nerves on cerebrovascular hypertrophy in developmental hypertension. Unilateral superior cervical ganglionectomy was performed in spontaneously hypertensive rats at 4 weeks of age, and wall-to-lumen ratios of cerebral arteries were determined ...

journal_title：Brain research

authors： Sadoshima S,Fujii K,Yao H,Ibayashi S,Fujishima M

更新日期：1986-08-06 00:00:00

abstract：:A basic experiment of peripheral nerve regeneration using neuronal progenitor cells embedded in collagen gel was performed in a rat sciatic nerve defect. First, when neuronal progenitor cells derived from the fetal rat hippocampus were cultured in atelocollagen-containing medium, neurospheres positive for anti-nestin ...

journal_title：Brain research

authors： Murakami T,Fujimoto Y,Yasunaga Y,Ishida O,Tanaka N,Ikuta Y,Ochi M

更新日期：2003-06-06 00:00:00

abstract：:The enzymatic and regulatory properties of Ca2+/calmodulin-dependent protein kinase in the postsynaptic density (mPSDp CaM kinase) of the rat forebrain was compared with those of soluble Ca2+/calmodulin-dependent protein kinase II (CaM kinase II). mPSDp CaM kinase was different from soluble CaM kinase II in terms of s...

journal_title：Brain research

authors： Ochiishi T,Sugiura H,Yamauchi T

更新日期：1993-04-30 00:00:00

abstract：:Beta-amyloid(1-42) peptide (betaAP) was injected into the right nucleus basalis magnocellularis (nbm) of rats. After a 14-day survival time, the acetylcholinesterase and choline acetyltransferase activities and the number of muscarinic receptors were found biochemically to be significantly reduced in the ipsilateral f...

journal_title：Brain research

authors： Harkany T,Lengyel Z,Soós K,Penke B,Luiten PG,Gulya K

更新日期：1995-10-09 00:00:00

abstract：:We have found that daily subcutaneous injection with a maximum tolerated dose (MTD) of the mGluR2/3 agonist LY379268 (20mg/kg) beginning at 4 weeks dramatically improves the phenotype in R6/2 mice. For example, we observed normalization of motor function in distance traveled, speed, the infrequency of pauses, and the ...

journal_title：Brain research

authors： Reiner A,Wang HB,Del Mar N,Sakata K,Yoo W,Deng YP

更新日期：2012-09-14 00:00:00

abstract：:The specific binding of [3H]neurotensin binding to the rat striatum was characterized and its localization investigated by using frontal cortex ablations and the neurotoxins kainic acid and 6-hydroxydopamine. Scatchard analysis indicated the existence of a single population of binding sites and the potencies of variou...

journal_title：Brain research

authors： Goedert M,Pittaway K,Emson PC

更新日期：1984-05-07 00:00:00

abstract：:The basic characteristics of the electroencephalograms (EEGs) of the entorhinal cortex (EC) were compared to those of the olfactory bulb (OB) and prepiriform cortex (PPC) in the awake cat, using methods that take into account linear (coherence functions) and non-linear relationships (mutual information). The frequency...

journal_title：Brain research

authors： Boeijinga PH,Lopes da Silva FH

更新日期：1988-05-17 00:00:00

abstract：:Studies of the subcellular localization of neuroreceptors in the rat brain have shown that most of them are associated with light and low density subcellular fractions. In two human brain areas, quite different subcellular distributions were observed. After fractionation by differential centrifugation of frontal corte...

journal_title：Brain research

authors： Maloteaux JM,Luabeya MK,Vanisberg MA,Jeanjean AP,Baudhuin P,Scherman D,Laduron PM

更新日期：1995-07-31 00:00:00

abstract：:We have previously shown that hypothyroidism produces a decrease in the number of spines counted along the apical shafts of pyramidal neurons of the cortex. Nevertheless, other authors have found that when an animal is subjected to some adverse living conditions the size of the spines decreases, making them invisible ...

journal_title：Brain research

authors： Berbel PJ,Escobar del Rey F,Morreale de Escobar G,Ruiz-Marcos A

更新日期：1985-07-01 00:00:00

abstract：:In recent years microvillar cells (MVC) have been identified in the olfactory epithelium of numerous species, including rodents, canines, and primates. However, there is no consensus on the morphologic or histochemical features of this cell, nor is the function of these cells currently known. Previous studies have exa...

journal_title：Brain research

authors： Miller ML,Andringa A,Evans JE,Hastings L

更新日期：1995-01-09 00:00:00

abstract：:Vascular basement membrane (BM) stabilizes brain vessels and inhibits endothelial cell cycle. Cerebral ischemia causes BM breakdown with the loss of structural BM components including collagens and laminins. In this study, the expression changes of the BM proteoglycan agrin, and the non-structural BM constituent SPARC...

journal_title：Brain research

authors： Baumann E,Preston E,Slinn J,Stanimirovic D

更新日期：2009-05-07 00:00:00

abstract：:It was previously reported that chronic food restriction and maintenance of rats at 75-80% of initial body weight enhanced the reward-potentiating effect of D-amphetamine in the lateral hypothalamic self-stimulation (LHSS) paradigm. Moreover, the enhancement reversed in parallel with body weight recovery when ad libit...

journal_title：Brain research

authors： Hao J,Cabeza de Vaca S,Pan Y,Carr KD

更新日期：2006-05-04 00:00:00

abstract：:Fibrates are activators of peroxisome proliferator-activated receptor (PPAR) α. Pretreatment with fibrates has been shown to protect brain against ischemia in mice. We hypothesized that fibrates elevate superoxide dismutase (SOD) levels in the brain microvessels (BMVs). BMVs were isolated from male C57BL/6 and PPARα n...

journal_title：Brain research

authors： Wang G,Liu X,Guo Q,Namura S

更新日期：2010-11-04 00:00:00

abstract：:Binding sites of atrial natriuretic peptide in the cerebral microvessels and choroid plexus of spontaneously hypertensive rats (SHR) and Wistar Kyoto control rats (WKY) were measured. In the microvessels, the number of ANP binding sites was lower in SHR than WKY, but there was no difference in affinity of binding site...

journal_title：Brain research

authors： Okazaki M,Kobayashi H,Kuroiwa A,Izumi F

更新日期：1990-06-04 00:00:00

abstract：:The purpose of this experiment was to determine whether increased secretion of somatostatin or alterations in its molecular form contribute to the age-related decline in growth hormone secretion. Median eminences were removed from male Sprague-Dawley rats (3-4 and 21-24 months of age) and superfused with Krebs-Ringer ...

journal_title：Brain research

authors： Sonntag WE,Gottschall PE,Meites J

更新日期：1986-08-20 00:00:00

abstract：:Sleep spindles may be involved in synaptic plasticity. Learning-dependent increases in spindles have been observed in both humans and rats. In humans, the innate (i.e., baseline) number of spindles correlate with measures of academic potential such as Intelligence Quotient (IQ) tests. The present study investigated if...

journal_title：Brain research

authors： Fogel SM,Smith CT,Beninger RJ

更新日期：2010-03-10 00:00:00

abstract：:The pedunculopontine nucleus (PPN) located in the mesopontine tegmentum is innervated by descending projections from nuclei in the basal ganglia. The present study was performed to determine whether nigrostriatal dopaminergic neuron degeneration is associated with changes in PPN metabolic activity. Unilateral nigrostr...

journal_title：Brain research

authors： Carlson JD,Pearlstein RD,Buchholz J,Iacono RP,Maeda G

更新日期：1999-05-15 00:00:00

abstract：:The effects of stimulating the reticular formation were studied during fictive locomotion in lampreys (Ichthyomyzon unicuspis). The in vitro isolated preparation of the brainstem and spinal cord was used and fictive locomotion was induced by bath application of N-methyl-D-aspartate (NMDA; 50-100 microM). During differ...

journal_title：Brain research

authors： Guertin P,Dubuc R

更新日期：1997-04-11 00:00:00

abstract：:Abeta amyloidosis and tauopathy are characteristic changes in the brain of Alzheimer's disease. Although much evidence suggests that Abeta deposit is a critical initiation factor, the pathological pathway between Abeta amyloidosis and tau accumulation remains unclear. Tau accumulation was examined in the doubly transg...

journal_title：Brain research

authors： Samura E,Shoji M,Kawarabayashi T,Sasaki A,Matsubara E,Murakami T,Wuhua X,Tamura S,Ikeda M,Ishiguro K,Saido TC,Westaway D,St George Hyslop P,Harigaya Y,Abe K

更新日期：2006-06-13 00:00:00