Abstract：
:Neurotensin is a putative peptide neurotransmitter in the mammalian brain. The light microscopic localization of the neurotensin receptor has been carried out by the autoradiographic localization of [3H]neurotensin binding sites in slide-mounted tissue sections. Large variations in receptor distribution were found, even in small areas. In many regions, the distribution of the receptor paralleled that of the immunoreactive neurotensin found in other studies. The results suggest sites of neurotensin's action in producing various physiological effects such as hypothermia and analgesia.
journal_name
Brain Resjournal_title
Brain researchauthors
Young WS 3rd,Kuhar MJdoi
10.1016/0006-8993(81)90532-1subject
Has Abstractpub_date
1981-02-16 00:00:00pages
273-85issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(81)90532-1journal_volume
206pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Projection neurons from the superior colliculus (SC) to the cuneiform region (CFR) of the midbrain form distinct cell clusters in the intermediate gray layer which precisely overlap the cholinergic fiber patches in this region of the cat SC (Jeon and Mize, J. Comp. Neurol., 337 (1993) 127-150). The acetylcholine (ACh)...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00563-x
更新日期：1996-09-16 00:00:00
abstract：:Spinally-projecting A5 neurons were studied with anatomical and electrophysiological techniques in the rat. A detailed study of the number and distribution of spinally-projecting catecholaminergic (CA) and non-catecholaminergic neurons present in a defined area of ventrolateral pontine reticular formation was performe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90206-3
更新日期：1984-06-11 00:00:00
abstract：:The muscarinic cholinergic receptor of rat eccrine sweat gland was characterized using quantitative autoradiography and [3H]QNB as radioligand. The distribution of radioligand was maximal in the secretory coil. Autoradiographic competition binding studies were performed using selective antagonists to M1 (pirenzepine),...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90415-r
更新日期：1991-05-31 00:00:00
abstract：:Glia represents the most numerous group of nervous system cells and CNS development and function depend on glial cells. We developed a purified Muller glia culture to investigate the expression of several neurotransmitter markers on these cells, such as dopaminergic, cholinergic, GABAergic and peptidergic receptors or...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.01.031
更新日期：2005-03-21 00:00:00
abstract：:Diabetes mellitus can lead to functional and structural deficits in both the peripheral and central nervous system. The pathogenesis of these deficits is multifactorial, probably involving, among others, microvascular dysfunction and alterations in intracellular calcium homeostasis. The present study examined the effe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.12.025
更新日期：2005-02-21 00:00:00
abstract：:In zebra finches, androgens stimulate song production and promote growth of the neural regions controlling song. Early exposure to estrogen establishes this sensitivity to androgens and increases the number of androgen-accumulating cells in two song regions, the hyperstriatum ventralis pars caudalis (HVc) and the magn...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90715-4
更新日期：1989-05-29 00:00:00
abstract：:Whole-cell patch-clamp recordings were used to investigate electrophysiological effects of neurotensin on acutely isolated dopaminergic (DA) neurons of the rat substantia nigra pars compacta (SNC). During current-clamp recordings, neurotensin depolarized DA neurons and triggered action potentials. Under voltage-clamp ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)00379-5
更新日期：1995-06-19 00:00:00
abstract：:Neurological problems can develop when blood glucose levels rapidly rise or fall yet there has been little experimentation at a cellular level to assess how neurophysiological change may be induced. Using intracellular recording in the rat neocortical slice preparation, we examined pyramidal neurons of layers II-III a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90859-t
更新日期：1991-07-26 00:00:00
abstract：:The peak-to-peak amplitude of temporal middle latency response (MLR) of the guinea pig, evoked by a click in the contralateral ear, according to the recording side, is increased with the presence of continuous white noise (CWN) in the ipsilateral ear and this specialty is defined as the white noise enhancement (WNE). ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.05.015
更新日期：2004-08-13 00:00:00
abstract：:Visual acuity was measured by determining the highest spatial acuity at which chickens aged 1-25 days jumped consistently to a physically supported grating instead of to an unsupported homogeneous field. In contrast to the gradual visual development found for kittens, monkeys, and humans, the chicken exhibits asymptot...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90967-7
更新日期：1981-05-04 00:00:00
abstract：:Leukocyte behavior in the cerebral microvasculature following vessel occlusion has not been fully elucidated. The purpose of this study was to investigate the effects of cilostazol on leukocyte behavior (rolling and adhesion) in murine cerebral microvessels following transient bilateral carotid artery occlusion using ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2013.11.017
更新日期：2014-01-16 00:00:00
abstract：:The anteroventral subdivision of the medial amygdala (MeAV) is one of the vomeronasal structures involved in the control of hormonally dependent behaviors such as sexual and agonistic behaviors in rats. The present study investigates some anatomical and neurochemical parameters of this nucleus (volume, number of neuro...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.02.073
更新日期：2007-05-30 00:00:00
abstract：:Determining the mechanism by which fluorescent retrograde neuronal tracers are taken up requires knowledge of their composition. It has been claimed that Fluoro-Gold, a retrogradely transported fluorescent neuronal tracer, is 2-hydroxy-4,4'-diamidinostilbene (hydroxystilbamidine), an amidine antibiotic. However, this ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90241-m
更新日期：1991-07-05 00:00:00
abstract：:Single pulse stimuli were delivered to the Schaffer collaterals in the in vitro hippocampal slice preparation. Local application of bicuculline to the CA3 region resulted in a series of population cell bursts in CA3, resembling the neuronal patterns which occur in the normal, freely moving rat during hippocampal sharp...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)91618-0
更新日期：1987-12-01 00:00:00
abstract：:Mitochondrial electron transport chain (ETC) function is selectively reduced in multiple tissues, including brain, from patients with Parkinson's disease (PD) and Alzheimer's disease (AD). The ETC defects are specific to each illness, involve complex I in PD and complex IV in AD, are transferable with mitochondrial DN...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00429-0
更新日期：1997-08-15 00:00:00
abstract：:The hetero-bifunctional nitroimidazole radiosensitizer CI-1010, R-alpha-[[(2-bromoethyl)-amino]methyl]-2-nitro-1H-imidazole-1-ethanol monohydrobromide, causes selective irreversible apoptotic loss of retinal photoreceptor cells in vivo. The human neuroblastoma cell line, SH-SY5Y, was used as a neuronotypic model of CI...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03838-6
更新日期：2003-02-14 00:00:00
abstract：:Following injections of WGA-HRP into lower cervical segments, the distribution of anterograde labeled terminals of spinocerebellar fibers was examined in the vermal cortex of the cat. The labeled terminals were seen in sublobules Ib to VIc, VIIb, VIIIa and VIIIb, and lobule IX. They were present mainly in the medial p...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91261-2
更新日期：1985-12-23 00:00:00
abstract：:We previously reported the presence of Erk2 type mitogen-activated protein kinase (MAPK) and enrichment of its substrates in the post-synaptic density (PSD) fraction, and suggested a role for MAPK in the synaptic transmission and its modulation [Suzuki, T., Okumura-Noji, K., Nishida, E., ERK2-type mitogen-activated pr...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01762-x
更新日期：1999-09-04 00:00:00
abstract：:In this study, we aimed at investigating the effect of an enriched environment (EE) on the recovery from chronic inflammatory pain. Inflammatory pain was induced by the injection of 2 mg of carrageenan (CAR) into the right knee of male Sprague-Dawley rats (n=34). Rats were housed either singly (S-housed) or in an EE (...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.04.039
更新日期：2009-06-18 00:00:00
abstract：:Prior studies indicate that, in tests of recognition memory, ERPs elicited by correctly recognized test items differ according to whether the items were encoded in an emotionally arousing or an emotionally neutral study context. These prior studies employed only a relatively brief (ca. 10 min) retention interval, howe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.02.082
更新日期：2009-05-07 00:00:00
abstract：:Previous studies have shown that long-term 5-hydroxytryptamine (5-HT) depletion induced by combined dorsal and median raphe injections of 5,7-dihydroxytryptamine (5,7-DHT) leads to impairments in the acquisition and performance of behaviour maintained under a differential-reinforcement-of-low-rate (DRL) schedule of re...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)00037-q
更新日期：1995-03-27 00:00:00
abstract：:The kinetic properties of the testosterone-metabolizing enzymes were studied in the hypothalamus of adult and young zebra finches of both sexes. Estradiol, 5 alpha-dihydrotestosterone, 5 beta-dihydrotestosterone and 5 beta-androstane-3 alpha,17 beta-diol were identified as metabolites of testosterone in males and fema...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90406-4
更新日期：1988-11-01 00:00:00
abstract：:The purpose of this study was to ascertain whether visual acuity or contrast sensitivity function (CSF) is proportional to visual cortical function based on fMRI volume and level of activation or Z-score. Forced choice procedures were utilized to measure the monocular log minimal angle of resolution (logMAR) visual ac...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.10.082
更新日期：2011-01-07 00:00:00
abstract：:Recordings of single unit activity before, during and after a 1-h continuous exposure were made from the mitral cell layer of the olfactory bulbs of awake rabbits. Thirteen complete 1-h exposures were performed using 8 neurons, while a further 6 neurons were lost before the end of the exposure. During the first few mi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90951-9
更新日期：1982-10-28 00:00:00
abstract：:Cytogenesis in the kitten retina has been investigated with [3H]thymidine autoradiography and a stain for mitotic figures. The nuclei of cells in S-phase are located adjacent to the inner margin of the cytoblast layer, near the inner plexiform layer. The nuclei then migrate toward the outer limiting membrane (OLM) to ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(85)90235-4
更新日期：1985-03-01 00:00:00
abstract：:Several lines of evidence indicate that psychostimulant withdrawal can induce negative emotional symptoms, such as anhedonia and dysphoria, which may be due in part, to dysfunction of the serotonin (5-HT) system, including alterations in 5-HT receptors. For example, changes in 5-HT(2A) receptor function in prefrontal ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.03.033
更新日期：2011-05-16 00:00:00
abstract：:This study investigated the long-lasting effects of chronic ethanol consumption on the distribution of Schaffer collateral-commissural (SCH/COM) afferents within stratum radiatum of rat hippocampal CA1. Experimental animals were fed an ethanol-containing liquid diet for 20 weeks but were withdrawn from the special die...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90559-5
更新日期：1982-04-08 00:00:00
abstract：:Previous electrophysiological as well as imaging research has contributed to the understanding of impairments in attention, executive functions, and memory in patients with attention-deficit/hyperactivity disorder (ADHD). However, there is a lack of studies investigating ADHD related differences in the gamma range of ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.06.023
更新日期：2008-10-15 00:00:00
abstract：:Metallothioneins (MTs) are metal-binding proteins that are expressed in many tissues including brain. MTs protect cells and organs against metal toxicity and oxidants. Among MTs, a brain-predominant subtype MT-III has prominent neuroprotective activity against various types of damage. Here we show that the expression ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(03)02633-7
更新日期：2003-06-20 00:00:00
abstract：:To address the question of whether fine myelinated and unmyelinated primary afferent fibers contribute to the mechanism of presynaptic inhibition in the spinal cord, we studied dorsal root-evoked dorsal root potentials (DR-DRPs) using a newly developed longitudinal spinal cord slice preparations in the adult rat. Sing...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)00619-2
更新日期：1995-09-11 00:00:00
