Abstract：
:Single pulse stimuli were delivered to the Schaffer collaterals in the in vitro hippocampal slice preparation. Local application of bicuculline to the CA3 region resulted in a series of population cell bursts in CA3, resembling the neuronal patterns which occur in the normal, freely moving rat during hippocampal sharp waves. These bicuculline-induced cell bursts in CA3 resulted in long-term potentiation (LTP) of the CA1 response. These findings suggest that the naturally occurring hippocampal sharp waves may reflect events analogous to artificially induced LTP.
journal_name
Brain Resjournal_title
Brain researchauthors
Buzsáki G,Haas HL,Anderson EGdoi
10.1016/0006-8993(87)91618-0subject
Has Abstractpub_date
1987-12-01 00:00:00pages
331-3issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(87)91618-0journal_volume
435pub_type
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