Abstract:
:Intracellular staining of neurons located in the superficial layers of the superior colliculus (SC) of the cat was carried out through an intracellular recording micropipette with which responses to stimulation of the optic chiasm (OX) and the optic tract (OT) ipsilateral to the explored SC were recorded. :A total of 16 SC neurons were successfully stained. Retinotectal fibers which were synaptically connected to those morphologically identified neurons were classified as either W- or Y-fibers according to their conduction velocities. The conduction velocity of W-fibers ranged from 4.0 to 13.1 m/sec and that of Y-fibers from 35.5 to 42.0 m/sec. Neurons located in the upper part of the stratum griseum superficiale (SGS) were found to be monosynaptically or polysynaptically supplied by W-fibers, while some neurons located in the lower part of SGS were monosynaptically connected to Y-fibers and others monosynaptically or polysynaptically to W-fibers. Morphologically SC neurons were classified as horizontal (1), narrow-field vertical (3), wide-field vertical type II (6) and type III cells (3) with 3 unidentified neurons. W-fibers were connected to the horizontal, narrow-field vertical and wide-field vertical type-II cells while Y-fibers contacted only wide-field vertical type-III cells.
journal_name
Brain Resjournal_title
Brain researchauthors
Ogawa T,Takahashi Ydoi
10.1016/0006-8993(81)90180-3subject
Has Abstractpub_date
1981-07-27 00:00:00pages
1-11issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(81)90180-3journal_volume
217pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::Monoclonal antibodies were produced against tyrosine hydroxylase (TH), the enzyme catalyzing the rate limiting step in catecholamine neurotransmitter synthesis. An enzyme linked immunosorbant assay was used to detect the presence of specific antibody in culture. Specificity of the antibodies is characterized. These mo...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90583-7
更新日期:1981-03-16 00:00:00
abstract::Electrophysiological techniques and the retrograde transport of horseradish peroxidase (HRP) were used to determine the efferent projections from the caudal mediobasal hypothalamus to the amygdala. In pentobarbital anesthetized rats, the activity of 1780 mediobasal hypothalamic neurons was examined for response to sti...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(77)90147-0
更新日期:1977-02-01 00:00:00
abstract::The glutamate analogue 2-amino-4-phosphonobutyric acid (AP4) is a potent antagonist at several synapses where an excitatory amino acid appears to be the neurotransmitter. Previous studies identified a Cl-/Ca2+ dependent [3H]glutamate binding site in synaptic plasma membrane (SPM) preparations that was also labeled by ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)90977-7
更新日期:1986-06-04 00:00:00
abstract::Methylazoxymethanol acetate (MAM)-induced cortical hypoplasia resulted in a 2-fold increase in the concentration of norepinephrine and its metabolite, 3-methoxyl-4-hydroxyphenylglycol sulfate, and a 26% decrease in the Bmax for the beta-receptor ligand, [3H]dihydroalprenolol (DHA) in the rat cortex. Chronic treatment ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(82)90195-x
更新日期:1982-08-01 00:00:00
abstract::c-Fos protein is a nuclear protein coded by c-fos proto-oncogene subsequent to synaptic activation of the neurons. We used immunohistochemical methods to visualize the expression of c-Fos protein in myenteric neurons of the guinea pig distal colon and examined the effects of the extrinsic autonomic inputs on the enter...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(02)02943-8
更新日期:2002-09-06 00:00:00
abstract::Murine brain cells differentiated for 19 days in culture before treatment for 5 days with 10 microM diazepam. Radioligand binding to the benzodiazepine receptors on membranes obtained from these cultures was determined by the filtration assay method. Decreased binding was observed in the membranes from treated culture...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)90117-8
更新日期:1983-12-12 00:00:00
abstract::The purpose of this study was to identify the functional fields activated in relation to the self-paced proximal and distal arm movements. The regional cerebral blood flow (rCBF) was measured with positron emission tomography (PET) and 15O-labelled H2O (H2(15)O) in eight healthy subjects. All subjects performed the fo...
journal_title:Brain research
pub_type: 临床试验,杂志文章
doi:10.1016/0006-8993(96)00032-7
更新日期:1996-04-15 00:00:00
abstract::Subcommissural organ (SCO) is a highly specialized ependymal gland located in the roof of the third ventricle. The secretory products of the SCO, which condense to form Reissner's fiber (RF), were recently found to cross-react with the anti-calcitonin antibody. To understand the mechanisms regulating the formation of ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)02144-7
更新日期:2000-01-10 00:00:00
abstract::Administration of non-competitive N-methyl-D-aspartate (NMDA) receptor antagonists (e.g. phencyclidine, MK-801) has been shown to elicit behavioral abnormalities related to symptoms of schizophrenia, such as spontaneous locomotor activity and impaired sensorimotor gating, as represented by deficits of prepulse inhibit...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.07.013
更新日期:2010-09-17 00:00:00
abstract::Stroke-prone spontaneously hypertensive rats (SHRSP) develop severe hypertension and cerebrovascular lesions. We investigated the influence of dietary supplementation with L-arginine, an amino acid precursor of endothelium-derived nitric oxide, on blood pressure and stroke in these rats. L-Arginine, administered in th...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90482-b
更新日期:1991-05-24 00:00:00
abstract::The present study combined masked priming with electrophysiological recordings to investigate orthographic priming effects with nonword targets. Targets were pronounceable nonwords (e.g., STRENG) or consonant strings (e.g., STRBNG), that both differed from a real word by a single letter substitution (STRONG). Targets ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.02.050
更新日期:2011-04-22 00:00:00
abstract::Cerebral autoregulation was tested here in 3- and 18-month-old spontaneously hypertensive rats (SHR) and Wistar Kyoto controls (WKY). Cerebral blood flow (CBF) was measured in each rat using radioactive micropheres under unanesthetized control conditions and after hypotension induced by ganglionic blockade. Under cont...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90454-6
更新日期:1981-06-09 00:00:00
abstract::This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.05.012
更新日期:2011-05-12 00:00:00
abstract::Distribution of adult T cell leukemia derived factor (ADF/TRX), a human thioredoxin homologue, was studied by immunohistochemistry in gerbil brain during reperfusion after transient cerebral ischemia. In control brains, immunoreactivity was observed widely in the central nervous system, including the ependyma, tanycyt...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)90130-f
更新日期:1993-10-15 00:00:00
abstract::Experiments have been performed on pentobarbitone anesthetized or decerebrated rats. The nature of the synchronous rhythmical activity which occurs in the inferior olive following the electrophoretic or systemic administration of harmaline, harmine, dihydro-beta-erythroidine and various other compounds, is described. ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(76)90471-6
更新日期:1976-01-23 00:00:00
abstract::Hypoxia-inducible transcription factors (HIFs) are crucially involved in brain development and cellular adaptation to hypoxia and ischemia. Degradation of HIF is regulated under normoxia by oxygen-dependent hydroxylation of specific prolyl residues on the labile alpha-subunit by HIF prolyl hydroxylases (PHD). Prolyl-4...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2009.05.023
更新日期:2009-07-14 00:00:00
abstract::MicroRNAs (miRNAs) are abundantly expressed in the brain and play an important role in disorders of the brain, including Alzheimer's diseases (AD). Growing body of evidence suggests that the TGF-β signaling pathway plays a key role in the pathogenesis of AD. However, it is unclear whether miRNAs involved in AD pathoge...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.08.023
更新日期:2010-10-21 00:00:00
abstract::We previously showed indirectly that the increase in diacylglycerol (DAG) levels caused by exposing differentiating PC12 cells to nerve growth factor (NGF) must derive mainly from de novo synthesis and, to a lesser and transient extent, from the hydrolysis of [3H]phosphatidylinositol (PI). To explore further the bioch...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)01280-3
更新日期:1999-02-13 00:00:00
abstract::The influence of dopamine D1 receptor agonist, SKF 38393 has been studied in vitro in the model of low calcium spontaneous epileptiform discharges. Application of SKF 38393 (3 microM) to the perfusing medium evoked a decrease in neuronal firing rate of hippocampal CA1 neurons. The effect of SKF 38393 was blocked by pr...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90208-s
更新日期:1990-09-24 00:00:00
abstract::Compound action potential recording techniques were used to investigate the time- and frequency-dependent effects of 4-aminopyridine (4-AP) and tetraethylammonium (TEA) on large diameter, fast conducting (t1) and medium diameter, middle conducting (t2) optic tract axons in anesthetized hooded rats. Single-pulse studie...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)91102-5
更新日期:1989-10-02 00:00:00
abstract::Neonatal hypoxia-ischemia (HI) has been extensively studied in a rat model characterized by unilateral brain damage (Rice-Vannucci Model). However, as well as in humans, each rat brain hemisphere is distinctly involved in cognitive functions, as for example retrieval of emotionally based memory, and neurochemical asym...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(03)02436-3
更新日期:2003-05-30 00:00:00
abstract::Hippocampal CA1 pyramidal neurons undergo delayed neurodegeneration after transient forebrain ischemia, and the phenomenon is dependent upon hyperactivation of l-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) subtype of glutamate receptors, resulting in aberrant intracellular calcium influx. The GluR2 sub...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.12.123
更新日期:2006-02-23 00:00:00
abstract::Met-enkephalin immunoreactive material content was found to be decreased in the cervical and thoracic segments of the spinal cord from rats aged 25 months as compared to young, 3-month-old, rats. No age-related variations were detectable at the lumbar level. Bio-Gel P 30 column chromatography of thoracic segment extra...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)90481-x
更新日期:1983-02-28 00:00:00
abstract::The optic nerve of anesthetized cats was completely cut and the autologous sciatic nerve was transplanted. Sixty days later some populations of retinal ganglion cells were shown to regenerate the axon with retrograde HRP labeling. We verified that ganglion cells that had projected to the lateral geniculate nucleus (LG...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91253-w
更新日期:1991-09-27 00:00:00
abstract::Migraine and anxiety disorders are frequently co-morbid with balance disorders. This study examined the relative distribution of subtypes of serotonin (5-HT) receptor in the inner ear of monkeys and rats. Most vestibular ganglion cells were immunoreactive for 5-HT(1B) and 5-HT(1D) receptors in macaques and rats. In th...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.05.057
更新日期:2010-07-30 00:00:00
abstract::The reversible blockade of geniculate PGO waves was carried out by localized cooling of the ponto-geniculate pathways during paradoxical sleep in chronic cats. In parallel, long-term recordings of unit activity were performed in non-specific visuooculomotor thalamic structures where no PGO waves occurred. Blockade of ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(77)90341-9
更新日期:1977-12-02 00:00:00
abstract::A lesion of the septum or a transection of the fimbria-fornix diminishes most, but not all, acetylcholinesterase (AChE) staining in the hippocampal formation. The residual AChE is located in the outer part of the molecular layer of the hippocampal CA1 zone and adjacent subicular field (zone 31). We report that followi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)90583-8
更新日期:1983-08-08 00:00:00
abstract::Tissue culture preparations of the myenteric plexus from the guinea pig taenia coli have been studied by electron microscopy. Three main cell types can be identified: neurons, enteric glial cells and fibroblasts. The ultrastructure of these cells resembles that of the same cells in situ. Neuronal processes form close ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)90467-5
更新日期:1983-02-28 00:00:00
abstract::Oxytocin properties have been studied in different experimental models in order to obtain evidence for its analgesic properties. The analgesic effect of an oxytocinergic pathway descending from the hypothalamus reaching the dorsal horn of the spinal cord has been studied. In anesthetized rats, we recorded single units...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.01.050
更新日期:2006-04-07 00:00:00
abstract::An increase in medial perforant synaptic strength can be observed for hippocampal slices from rats exposed to environmental enrichment. The expression of enhanced synaptic strength exhibits properties similar to long-term potentiation (LTP), a physiological model of memory storage. Similarities include an increase in ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00707-x
更新日期:1996-10-14 00:00:00