Quantitative correlation between tetanus-induced decreases in extracellular calcium and LTP.

abstract：:Endothelin (ET), a potent vasoconstrictor peptide, is believed to have central sites of action and potential neurohormonal effects relating to body fluid homeostasis and blood-pressure regulation. Systemic endothelin binds to receptors at circumventricular organs and has been shown to increase plasma concentrations of...

journal_title：Brain research

authors： Wall KM,Nasr M,Ferguson AV

更新日期：1992-01-20 00:00:00

abstract：:Expression of the immediate-early gene c-fos, a marker of neuronal activation, was employed to localize brainstem neuronal populations functionally related to the expiration reflex (ER). Twelve spontaneously breathing, non-decerebrate, pentobarbital anesthetized cats were used. The level of Fos-like immunoreactivity (...

journal_title：Brain research

authors： Poliacek I,Halasova E,Jakus J,Murin P,Barani H,Stransky A,Bolser DC

更新日期：2007-12-12 00:00:00

abstract：:In this study, seizures in the dentate gyrus were triggered by 2 Hz electrical stimulation while, at the same time, serial changes in paired-pulse depression was measured in free-moving rats. The perforant path was stimulated by paired pulses 25 ms apart and recordings were made in the dentate gyrus. We also observed ...

journal_title：Brain research

authors： Emori K,Katsumori H,Minabe Y

更新日期：1997-11-21 00:00:00

abstract：:Histaminergic neurons of the tuberomammillary nucleus (TMN) are hypothesized to promote wakefulness, but little is known about the activity of these cells during spontaneous behavior. We measured histaminergic neuron activity in the dorsomedial, ventrolateral, and caudal TMN at four different times using Fos and adeno...

journal_title：Brain research

authors： Ko EM,Estabrooke IV,McCarthy M,Scammell TE

更新日期：2003-12-05 00:00:00

abstract：:Several studies have demonstrated in the past that endogenous opioid peptides and opioid receptors may be involved as mediators of brain tissue growth and function in the neonate. Applying histological and autoradiographic methods, we have examined the effect of the mu-receptor-specific antagonist, naltrexone, on the ...

journal_title：Brain research

authors： Schmahl W,Funk R,Miaskowski U,Plendl J

更新日期：1989-05-08 00:00:00

abstract：:The immunosuppressive macrolide FK-506 has been shown to protect neurons in culture against glutamate excitotoxicity. This effect was attributed to the binding of immunosuppressants to calcineurin-inhibiting immunophilins. We now report that also the non-immunosuppressive macrolide antibiotics protect neurons in cultu...

journal_title：Brain research

authors： Manev H,Favaron M,Candeo P,Fadda E,Lipartiti M,Milani D

更新日期：1993-10-08 00:00:00

abstract：:Extracellular and intracellular recordings have been made from non-pyramidal neurones in the rat hippocampus in vivo and in vitro. These cells were situated in the stratum pyramidale but were orthodromically activated with a lower threshold than pyramidal neurones in response to stimulation of the Schaffer collateral/...

journal_title：Brain research

authors： Ashwood TJ,Lancaster B,Wheal HV

更新日期：1984-02-20 00:00:00

abstract：:Kinins, a special class of polypeptides, are represented by bradykinin (BK), kallidin (Lys-BK), as well as their metabolites. The biological actions of these polypeptides binding on their receptors (B1 and B2) have been related to inflammation process, cytokines action, glutamate release and prostaglandins production....

journal_title：Brain research

authors： Argañaraz GA,Silva JA Jr,Perosa SR,Pessoa LG,Carvalho FF,Bascands JL,Bader M,da Silva Trindade E,Amado D,Cavalheiro EA,Pesquero JB,da Graça Naffah-Mazzacoratti M

更新日期：2004-04-23 00:00:00

abstract：:The aim of this study was to examine: (1) whether long-term potentiation (LTP) can be induced in slices from adult rat visual cortex under conditions where inhibition is not antagonized, and (2) the role of N-methyl-D-aspartate (NMDA) receptors in its induction. The field potential elicited in layer III in response to...

journal_title：Brain research

authors： Aroniadou VA,Teyler TJ

更新日期：1992-07-03 00:00:00

abstract：:Atropine (5 nM to 5 muM), but not D-tubocurarine or hexamethonium, enhanced the release of acetylcholine (ACh) from rat brain cortical slices exposed to high K+. The enhancement was dose-dependent, and it could be partially antagonized by oxotremorine (50-500 muM) or by dibutyryl or 8-bromo-cyclic GMP (1 mM), but not ...

journal_title：Brain research

authors： Yonehara N,Matsuda T,Saito K,Ishida H,Yoshida H

更新日期：1980-01-20 00:00:00

abstract：:Our previous study reported that cathepsin L may contribute to the death of dopaminergic neurons in rodent model of Parkinson's disease (PD). In this study we detected the changes in the expression of lysosomal cathepsin L in cellular models of PD. In human neuroblastoma SH-SY5Y cells, treatment with 6-hydroxydopamine...

journal_title：Brain research

authors： Xiang B,Fei X,Zhuang W,Fang Y,Qin Z,Liang Z

更新日期：2011-04-28 00:00:00

abstract：:In albino rats the deep layers of the superior colliculus were stimulated, and climbing fiber responses of Purkinje cells were explored in the medial region of the lobulus simplex. They were identified in a strip (ca. 0.7-1.0 mm wide) in the most medial region of folium b. In the tectorecipient zone of the medial acce...

journal_title：Brain research

authors： Akaike T

更新日期：1987-08-11 00:00:00

abstract：:The effects of adenosine and the adenosine binding enhancer, PD 81,723, on low magnesium-induced bursting in the in vitro hippocampal slice were examined. Extracellular recordings were obtained from the CA3 pyramidal cell layer while electrically stimulating in the stratum radiatum under low magnesium perfusion. Adeno...

journal_title：Brain research

authors： Janusz CA,Berman RF

更新日期：1993-08-13 00:00:00

abstract：:This manuscript describes the use of staining of Fos-related antigens (FRAs) as markers for changes in neuronal activity. The model system consisted of the tuberoinfundibular dopamine (TIDA) neurons located in the arcuate nucleus of the hypothalamus. Under normal conditions, these neurons are devoid of c-Fos staining ...

journal_title：Brain research

authors： Hoffman GE,Le WW,Abbud R,Lee WS,Smith MS

更新日期：1994-08-22 00:00:00

abstract：:Parvalbumin (PV)-immunoreactive neurons in rat neostriatum were studied under light and electron microscopes. A small number of neurons in the striatum were immunoreactive for PV (a Ca-binding protein). Most of them were also strongly immunoreactive for glutamate decarboxylase but were negative for NADPH-diaphorase ac...

journal_title：Brain research

authors： Kita H,Kosaka T,Heizmann CW

更新日期：1990-12-17 00:00:00

abstract：:The distribution and subcellular localization of AH9 antigen, recognized by a monoclonal antibody AH9, were examined in rat brain. Highest expression was observed in the lamina lucidum of the dentate gyrus of the rat hippocampus. Synaptic subfields of other limbic areas also expressed AH9 antigen at a substantial leve...

journal_title：Brain research

authors： Fukuyama R,Rapoport SI

更新日期：1996-05-06 00:00:00

abstract：:Pituitary adenylate cyclase activating polypeptide (PACAP) is a hypothalamic peptide that affects anterior pituitary cell function. This study examined the effects of PACAP on prolactin (PRL) release in vivo and on tyrosine hydroxylase (TH) activity in tuberoinfundibular dopaminergic neurons in vivo and in vitro. In o...

journal_title：Brain research

authors： Arbogast LA,Voogt JL

更新日期：1994-08-29 00:00:00

abstract：:The morphology of so-called interplexiform (IP) cells immunoreactive to tyrosine hydroxylase (TH) or somatostatin (SOM) in the rat retina was described in comparison with those in the carp retina. In frozen cross-sections of the rat retina, many processes of TH-like immunoreactive cells were found to extend toward the...

journal_title：Brain research

authors： Negishi K,Kato S,Teranishi T,Kiyama H,Katayama Y,Tohyama M

更新日期：1985-10-28 00:00:00

abstract：:Glutamate is a major neurotransmitter in the CNS. Its release activates NMDA and non-NMDA receptors on the postsynaptic membrane. NMDA receptor activation is shown to be important in physiological and pathological events. The modulatory sites on the NMDA receptor-channel ionophore complex are important in the regulati...

journal_title：Brain research

authors： Saybasili H

更新日期：1998-03-09 00:00:00

abstract：:In the central nervous system (CNS) insulin mediates a variety of effects including feeding, metabolism and cognition. The cognitive enhancing effects of insulin are proposed to be mediated through activation of insulin receptors in the hippocampus, an important integration center for learning and memory in the mammal...

journal_title：Brain research

authors： Grillo CA,Piroli GG,Hendry RM,Reagan LP

更新日期：2009-11-03 00:00:00

abstract：:Some kinds of nociception appear to be partially mediated by the release of substance P (SP) in the spinal cord dorsal horn from terminals of primary afferent nociceptors. Only some nociceptors contain and release SP however. Specifically, SP appears to be released by unmyelinated (C) nociceptive afferents when activa...

journal_title：Brain research

authors： Zachariou V,Goldstein BD,Yeomans DC

更新日期：1997-03-28 00:00:00

abstract：:The neuroprotective effects of N-stearoyl-L-tyrosine (NSTyr) on cognitive function and neuronal plasticity during chronic cerebral hypoperfusion (CCH) in rats were investigated. After induction of CCH, NSTyr was administered daily for 3 months intraperitoneally. Cognitive functions were evaluated by Morris water maze ...

journal_title：Brain research

authors： Lin Q,Hai J,Yao LY,Lu Y

更新日期：2010-04-14 00:00:00

abstract：:Unilateral injections of 6-hydroxydopamine into the substantia nigra in the rat significantly attenuated cortical spreading depression (CSD)-induced eating from the hemisphere ipsilateral but not contralateral to the lesion. The lateralized decrease in elicited feeding was correlated with postlesion body weight loss, ...

journal_title：Brain research

authors： Siegfried B,Hefti F,Lichtensteiger W,Huston JP

更新日期：1979-01-12 00:00:00

abstract：:Unanesthetized adult male rats with indwelling right atrial cannulae were used in the majority of experiments. Morphine (MOR, 3.0 mg/kg) caused a large but transient increase in both GH and PRL levels, which could be prevented with naloxone. Disruption of central noradrenergic function with diethyldithiocarbamate (400...

journal_title：Brain research

authors： Koenig J,Mayfield MA,Coppings RJ,McCann SM,Krulich L

更新日期：1980-09-22 00:00:00

abstract：:In 16-week-old Sprague-Dawley rats lightly anesthetized with pentobarbital, 5-HT (3-96 micrograms/kg, i.v.; n = 6) produced distinct pseudaffective responses and a dose-dependent (slope = 17.2 +/- 6.8 s/log10 dose) inhibition of the tail-flick (TF) reflex (ED50 = 32.6 +/- 9.2 micrograms/kg). In the same rats, a 1:1 co...

journal_title：Brain research

authors： Meller ST,Lewis SJ,Brody MJ,Gebhart GF

更新日期：1991-10-04 00:00:00

abstract：:Previous studies have shown that one of the genetic variants BDNF val66met polymorphism is associated with drug addiction. Age at onset for drugs abuse has also been regularly cited as a factor associated with high genetic predispositions. We conducted an exploratory research to investigate the association of BDNF val...

journal_title：Brain research

authors： Hou H,Qing Z,Jia S,Zhang X,Hu S,Hu J

更新日期：2010-09-24 00:00:00

abstract：:A correlated intracellular and extracellular study of lumbar motoneuron excitability during sleep and wakefulness was performed in the chronic, unanesthetized, undrugged, normally respiring cat. Experiments were designed to reveal the extent to which hypotonia during active sleep in mammals is dependent on postsynapti...

journal_title：Brain research

authors： Morales F,Chase MH

更新日期：1981-11-30 00:00:00

abstract：:Orexin-A (OX-A) and -B (OX-B) peptides present in the hippocampus are considered to be exclusively contained in fibers arising from hypothalamus neurons, which were established as the only source of orexins (OXs). Because OX-A is known to exert excitatory actions in the hippocampus, we hypothesized that the level of O...

journal_title：Brain research

authors： Morales A,Bonnet C,Bourgoin N,Touvier T,Nadam J,Laglaine A,Navarro F,Moulin C,Georges B,Pequignot JM,Bezin L

更新日期：2006-09-13 00:00:00

abstract：:The aim of this study was to investigate the degree of functional and anatomical overlap between two major neuronal subpopulations in the rostral ventrolateral medulla: pre-sympathetic (sympathoexcitatory) neurons, and expiratory neurons of the Bötzinger complex. Extracellular recordings were made with dye-filled micr...

journal_title：Brain research

authors： Kanjhan R,Lipski J,Kruszewska B,Rong W

更新日期：1995-11-13 00:00:00

abstract：:There have been few reports concerning facilitation and depression in sympathetic ganglia9,17,40. In the present investigation, pairs of excitatory postsynaptic potentials (EPSPs) were recorded intracellularly from bullfrog paravertebral sympathetic ganglia for an analysis of the site and mechanism responsible for the...

journal_title：Brain research

authors： Tashiro N,Gallagher JP,Nishi S

更新日期：1976-12-10 00:00:00