Abstract:
:The peak-to-peak amplitude of temporal middle latency response (MLR) of the guinea pig, evoked by a click in the contralateral ear, according to the recording side, is increased with the presence of continuous white noise (CWN) in the ipsilateral ear and this specialty is defined as the white noise enhancement (WNE). This phenomenon is evaluated as an interesting electrophysiological finding from the viewpoint of binaural interaction and in this study, its dynamic specifications were investigated. After the beginning of ipsilateral CWN, significant WNE was observed at 275th ms and it reached to a maximum, with an increase more than 40%, at 350th ms. After a habituation occurred, WNE reached to 20% on the 4th second by gradually decreasing and came to a steady state. In the time window between 2 and 5 ms after CWN started, a surprising amplitude decrease is observed. Therefore, CWN causes an effect, like a click, in the short-term and this on-response type effect originates from low level binaural centers, which decreases the MLR amplitude. However, the same CWN increases the MLR amplitude (WNE) by the effects over the high level binaural centers in the succeeding period, by its continuous characteristic.
journal_name
Brain Resjournal_title
Brain researchauthors
Goksoy C,Demirtas S,Ungan Pdoi
10.1016/j.brainres.2004.05.015subject
Has Abstractpub_date
2004-08-13 00:00:00pages
61-8issue
1-2eissn
0006-8993issn
1872-6240pii
S0006899304007425journal_volume
1017pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::For the evaluation of glutamatergic and GABAergic transmission during seizures, rat hippocampal CA1 and CA3 areas were separately assessed by brain microdialysis, and extracelluar glutamate and GABA were measured through the course of the seizures after a systemic administration of kainic acid (KA). The generalized co...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00507-1
更新日期:1998-07-27 00:00:00
abstract::In the brain, nitric oxide (NO) has been identified as a messenger molecule and a mediator of excitatory amino acid-induced neurotoxicity. In this study, the effects of NO on serum-induced mitogenesis and cell proliferation of the cerebellar glial cells were assessed. NO-generating agent, S-nitroso-N-acetylpenicillami...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)91678-8
更新日期:1992-10-02 00:00:00
abstract::Dopamine neurons are overstimulated by drugs of abuse and suffer molecular alterations that lead to addiction behavior. Nurr1 is a transcription factor crucial for dopamine neurons survival and dopamine production, activating the transcription of key genes like tyrosine hydroxylase (TH). Interestingly, nuclear factor-...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2016.09.031
更新日期:2016-12-01 00:00:00
abstract::The accumulation of acid-labile CO2 was measured in the rat brain at early times after exposure to 30% CO2 in oxygen. In particular, the effect on CO2 accumulation of inhibiting brain carbonic anhydrase with acetazolamide was studied. For 57 rats, a rat head perfusion technique was used which permits control and rapid...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90443-6
更新日期:1980-09-15 00:00:00
abstract::parkin is the most frequent causative gene among familial Parkinson's disease (PD). Although parkin deficiency induces autosomal recessive juvenile parkinsonism (AR-JP, PARK2) in humans, parkin knockout (PKO) mice consistently show few signs of dopaminergic degeneration. We aimed to directly measure evoked extracellul...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.06.065
更新日期:2010-09-17 00:00:00
abstract::Intraocular injections of tetrodotoxin were used to block activity for 27 days in normal fish and for the first 27 or 31 days of regeneration in fish with one optic nerve crushed. Synaptic activity was then assessed by a current source-density analysis of field potentials evoked by optic nerve shock at different times...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)90958-7
更新日期:1983-06-13 00:00:00
abstract::The neurobiology of social bonding, despite its relevance to human mental health, has been studied primarily in rodents. In this study we used position emission tomography (PET), registered with structural magnetic resonance imaging (MRI) to investigate central glucose uptake in 17 males of a monogamous primate specie...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.09.087
更新日期:2007-12-12 00:00:00
abstract::The effects of indomethacin (10 mg/kg) on the release of the transmitter amino acids, glutamate, aspartate, GABA, and of the purines, adenosine and inosine, from the cerebral cortex was studied in a four-vessel occlusion rat model of cerebral ischemia/reperfusion. In comparison with the control group, indomethacin sig...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)90248-8
更新日期:1994-08-01 00:00:00
abstract::Synaptic potentials evoked in the medial amygdala (m-AMG) neurons were studied in in vitro slice preparations obtained from normal and olfactory bulbectomized rats. Local stimulation induced a sequence of responses: a fast EPSP, a fast IPSP and a slow EPSP. The fast EPSP was suppressed by kynurenic acid (KYN) at a con...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)91743-z
更新日期:1990-11-05 00:00:00
abstract::Following transection of a peripheral nerve in mice, a newly synthesized neurotropic pyrimidine compound, MS-818 was administered intraperitoneally at a dose of 1 mg kg-1 b.wt. day-1. The film model experiments for analyzing the early growth of axonal regeneration suggested that MS-818 activated Schwann cells which mi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)01491-1
更新日期:1998-03-23 00:00:00
abstract::Some occluded arteries of acute ischemic stroke (AIS) patients are not recanalized, even if thrombolytic therapy is performed. Considering such clinical settings, we examined the potential cerebroprotective efficacy of TAK-937, a novel cannabinoid receptor agonist, in young adult and aged rats with a permanent middle ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2013.06.014
更新日期:2013-08-14 00:00:00
abstract::Intracellular staining of neurons located in the superficial layers of the superior colliculus (SC) of the cat was carried out through an intracellular recording micropipette with which responses to stimulation of the optic chiasm (OX) and the optic tract (OT) ipsilateral to the explored SC were recorded. :A total of ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90180-3
更新日期:1981-07-27 00:00:00
abstract::Marmoset monkeys (Callithrix jacchus) with bilateral transections of the anterior temporal stem, amygdala and fornix were unable to relearn a 2-choice object discrimination first learnt prior to surgery, and were very severely impaired at relearning a concurrent object discrimination task which they had learnt and rel...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02998-x
更新日期:2001-01-05 00:00:00
abstract::The occurrence of unmyelinated axons was examined ultrastructurally in rat molar and incisor root pulps of normal rats, of neonatally capsaicin-treated rats, of rats subjected to neonatal capsaicin treatment followed by resection of the superior cervical ganglion and of sympathectomized but otherwise normal rats. Foll...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)90533-1
更新日期:1988-10-25 00:00:00
abstract::It has been accepted that the descending system from the nucleus locus coeruleus (LC)/nucleus subcoeruleus (SC) plays a significant role in spinal nociceptive processing. The present study was designed to examine modulation of nociceptive processing in the caudal part of the trigeminal sensory nuclear complex, the tri...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2003.09.023
更新日期:2003-12-12 00:00:00
abstract::Melatonin is a hormone that mostly produced from the pineal gland, and it performs as a strong neuroprotectant to both neuron and glial cells against methamphetamine (METH)-induced neurotoxicity. Recently, it has been found that METH also damages the blood brain barrier (BBB) structure and function. However, the prote...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2016.08.045
更新日期:2016-11-01 00:00:00
abstract::Previously, we have shown that intracisternal (i.c.) administration of beta-endorphin suppresses brain and liver DNA synthesis in rat pups. This finding is consistent with the view that endogenous CNS beta-endorphin plays an important role in controlling postnatal growth. Recent evidence suggests that brain CCK8, the ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91175-4
更新日期:1994-10-24 00:00:00
abstract::Thermoregulation is a complex intercommunicative function requiring coordination between core body temperature (CBT), the central nervous system, and peripheral vasculature. In menopausal women, dysregulation of thermoregulatory mechanisms leads to hot flushes and night sweats. A previous study in ovariectomized (OVX)...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.09.050
更新日期:2006-12-06 00:00:00
abstract::SBA and NADPH-d histochemistries allow identification of functionally distinct components of the amphibian primary olfactory system. In Pipa, a secondarily aquatic frog, combination of both methodologies, using alternate sets of histological sections, reveals that, apart from Jacobson's organ, this species has a "wate...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)00507-6
更新日期:1997-07-11 00:00:00
abstract::Intracisternal (i.c.) administration of the glutamate-receptor antagonist kynurenate to halothane-anesthetized rats (paralyzed, ventilated) produced an initial hypertension associated with an increase in lumbar sympathetic nerve discharge. Kynurenate (i.c.) blocked or greatly reduced all sympathetic reflexes investiga...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)91320-0
更新日期:1988-01-12 00:00:00
abstract::Previous reports from our laboratory have demonstrated that ethanol- and cannabinoid-induced ataxia is modulated by cerebellar adenosine A(1) receptor because intracerebellar (i.c.b.) adenosine A(1) agonists potentiated and A(1) antagonist attenuated ataxia by these psychoactive drugs. In this study, the novel approac...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(02)03599-0
更新日期:2002-12-06 00:00:00
abstract::In the adult brain, γ-amino butyric acid (GABA) is an inhibitory neurotransmitter, whereas it acts as an excitatory transmitter in the immature brain, and may be involved in morphogenesis. In the present study, we immunohistochemically examined the developmental changes in GABA signaling in the embryonic mouse cervica...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2012.10.003
更新日期:2012-11-27 00:00:00
abstract::The distribution of hypocretin-1 (hcrt-1) and hypocretin-2 (hcrt-2) immunoreactivities in the cat brainstem was examined using immunohistochemical techniques. Hcrt-1- and hcrt-2-positive fibers with varicosities were detected in almost all brainstem regions. However, no hcrt-1- or hcrt-2-immunoreactive neuronal somata...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2003.10.004
更新日期:2004-01-09 00:00:00
abstract::A pathway from the pretectal region to the dorsal division of the lateral geniculate body has been studied by autoradiography in adult cats following injection of tritium-labeled amino acids into the meso-diencephalic border zone. The findings suggest that the pretecto-geniculate connection arises in the ipsilateral n...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90861-6
更新日期:1980-08-11 00:00:00
abstract::A direct projection from rat mesencephalic trigeminal nucleus (Vme) neurons to the hypoglossal nucleus (XII) motoneurons was studied using a double labeling method of anterogradely biotinylated dextran amine (BDA) tracing combined with retrogradely horseradish peroxidase (HRP) transport at both light and electron micr...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)02911-0
更新日期:2001-10-26 00:00:00
abstract::The horizontal and vertical vestibulo ocular reflex (VOR) of head tilted (het) mutant mice was compared to C57BL/6 controls. Eye movements were recorded in darkness using a temporarily attached search coil. Contributions of semicircular canal versus otolith organ signals were investigated by providing a canal only (ve...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(03)02505-8
更新日期:2003-05-16 00:00:00
abstract::We developed a new model of embolic cerebral ischemia in the rat which provides a reproducible and predictable infarct volume within the territory supplied by the middle cerebral artery (MCA). The MCA was occluded by an embolus in Wistar rats (n = 71). An additional three non-embolized rats were used as a control. Cer...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)00580-5
更新日期:1997-08-22 00:00:00
abstract::Although nitric oxide (NO) has been shown to play an important role in the pathophysiology of cerebral ischemia, its contribution to the pathogenesis of experimentally induced thromboembolic stroke is unknown. In this study, we pharmacologically manipulated NO levels in the acute post-thrombotic stage and determined t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)00200-x
更新日期:1997-06-06 00:00:00
abstract::Using the hippocampal slice preparation, extracellular recordings of CA3 field excitatory postsynaptic potentials (fEPSPs) were performed to assess the effects of adenosine on the induction of mossy fiber long-term potentiation (LTP). When present during tetanization, adenosine (50 microM) significantly suppressed mos...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91061-5
更新日期:1991-03-08 00:00:00
abstract::Repeated amphetamine administration produced behavioral sensitization to subsequent amphetamine challenge. The development of sensitization was blocked by coadministration of the N-methyl-D-aspartate (NMDA) antagonist MK-801. Conditioned locomotion, as revealed by saline challenge, was also blocked by MK-801, suggesti...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91202-c
更新日期:1991-10-18 00:00:00