Adenosine depresses induction of LTP at the mossy fiber-CA3 synapse in vitro.

abstract：:Growth hormone releasing factor (GRF) applied by iontophoresis, pressure, and in the perfusate, increased (14.81%) or decreased (45.92%) the firing of paraventricular neurons extracellularly recorded from guinea-pig hypothalamic slices. Effects were similar whatever the mode of application and were elicited in the nan...

journal_title：Brain research

authors： Poulain P,Carette B

更新日期：1986-04-23 00:00:00

abstract：:Habituation kinetics were found to vary considerably in different polysynaptic pathways of the brain stem in man. The exteroceptive reflex of the digastric muscle habituates markedly, even for stimuli repeated at 1-min intervals. The second component of the blink reflex habituates for intervals below about 8 sec, but ...

journal_title：Brain research

authors： Desmedt JE,Godaux E

更新日期：1976-04-16 00:00:00

abstract：:The thalamic midline/intralaminar complex is part of the higher-order thalamus, which receives little sensory input, and instead forms extensive cortico-thalamo-cortical pathways. The midline thalamic nuclei connect with the medial prefrontal cortex and the medial temporal lobe. On the other hand, the intralaminar nuc...

journal_title：Brain research

authors： Silva Ade M,de Santana MA,Morais PL,de Sousa TB,Engelberth RC,Lucena EE,Campêlo CL,Cavalcante JS,Cavalcante JC,Costa MS,do Nascimento ES Jr

更新日期：2014-10-24 00:00:00

abstract：:The myelin vacuolation (mv) rat exhibits hypomyelination and vacuole formation in the myelin throughout the CNS, caused by a null mutation in the attractin gene. Myelin alterations in the spinal cord of mv rats progress during postnatal development and are more prominent in the white matter. In contrast, microglial ac...

journal_title：Brain research

authors： Izawa T,Yamate J,Franklin RJ,Kuwamura M

更新日期：2010-02-02 00:00:00

abstract：:We have previously demonstrated resiniferatoxin (RTX) to be an ultrapotent analog of capsaicin. Like capsaicin, RTX initially induces neurogenic inflammation, pain, and hypothermia and then causes desensitization of these responses. We examine here the duration of desensitization following acute treatment with the max...

journal_title：Brain research

authors： Szallasi A,Joo F,Blumberg PM

更新日期：1989-11-27 00:00:00

abstract：:A polyclonal antiserum raised against the carboxy-terminal 17 amino acids of the rat p185c-neu (anct) reacted with a 140 kDa polypeptide in membranes of synaptosome fractions from neocortex and hippocampus of 11-day-old and adult rats. The same antiserum reacted with a 185 kDa polypeptide in microsome membranes from r...

journal_title：Brain research

authors： Stieber A,Chen Y,Gonatas J,Dougall W,Qian X,O'Rourke D,Samanta A,Greene MI,Gonatas NK

更新日期：1995-11-27 00:00:00

abstract：:A new quantitative staining technique for the assay of protein in tissue sections using the dye Coomassie brilliant blue G 250 is discussed. This densitometric procedure uses commercially available hardware and software employed in the quantitation of receptor autoradiographs. Rather than assuming a homogeneous distri...

journal_title：Brain research

authors： Miller JA,Curella P,Zahniser NR

更新日期：1988-04-26 00:00:00

abstract：:Of 602 rats tested for amphetamine-induced or nocturnal rotation (circling behavior), 54.8% (P less than 0.025) had right side biases. Of 292 rats tested in two-lever operant situations, 57.5% (P less than 0.02) preferred the right lever. Right-biased rats were significantly more active and had stronger side preferenc...

journal_title：Brain research

authors： Glick SD,Ross DA

更新日期：1981-01-26 00:00:00

abstract：:In the course of pulse-label studies on the axonal transport of the small, basic, actin-binding proteins--actin depolymerizing factor, cofilin and profilin--in chicken motor neurones, we observed a heavily labelled protein of M(r) 18 kDa and pI 8.2 on fluorographs of two-dimensional polyacrylamide gels. On the basis o...

journal_title：Brain research

authors： Yuan A,Mills RG,Bamburg JR,Bray JJ

更新日期：1997-10-17 00:00:00

abstract：:We used rabbit antisera against manganese (Mn)-superoxide dismutase for immunohistochemical studies of localization in the rat neostriatum. Immunostaining was intense in large-sized neurons and several medium-sized neurons, but it was moderate to weak in other cells. Double immunostaining with monoclonal antibody to c...

journal_title：Brain research

authors： Inagaki S,Suzuki K,Taniguchi N,Takagi H

更新日期：1991-05-17 00:00:00

abstract：:The aim of this study was to test the role of the perifornical hypothalamus and adjacent areas in the behavioral and cardiovascular responses to two forms of stress, conditioned fear to context and restraint. Of particular interest was the role of the hypocretin (orexin) containing neurons in these responses. Rats imp...

journal_title：Brain research

authors： Furlong T,Carrive P

更新日期：2007-01-12 00:00:00

abstract：:4-Aminopyridine (4-AP), bicuculline and GABA were applied locally to dorsal horn cells in the lumbar spinal cord in Nembutal-anaesthetized cats and in spinal cats. 4-AP expanded the cutaneous receptive field of 29 of 33 cells tested. Bicuculline and GABA had little or no effect on receptive field size. ...

journal_title：Brain research

authors： Saadé N,Jabbur SJ,Wall PD

更新日期：1985-10-07 00:00:00

abstract：:In this study intracellular recording techniques were used to study the synaptic events related to phase-locking of cochlear nucleus cells to low frequency stimuli. A variable degree of phase-locking was noted even with units of the same low characteristic frequency. With low frequency phase-locking units an excitator...

journal_title：Brain research

authors： Britt RH

更新日期：1976-08-13 00:00:00

abstract：:The mouse auditory neurons, hair cells and their supporting cells in the cochlea are considered to be generated mainly in the embryonic days and to be sustained throughout the whole life. In the present study, however, we observed that auditory ganglion cells in the spiral ganglia undergo apoptosis and mitosis in the ...

journal_title：Brain research

authors： Kamiya K,Takahashi K,Kitamura K,Momoi T,Yoshikawa Y

更新日期：2001-05-18 00:00:00

abstract：:IL-10 reduces pro-inflammatory responses after ischemic stroke primarily by acting on glia and endothelium, but relatively little is known about the direct effects of IL-10 on cortical neurons, which are often damaged in stroke. We found by PCR and immunohistochemistry that cortical neurons express IL-10 receptor. Tre...

journal_title：Brain research

authors： Sharma S,Yang B,Xi X,Grotta JC,Aronowski J,Savitz SI

更新日期：2011-02-10 00:00:00

abstract：:Cerebral ischemia initiates an inflammatory response in the brain that is associated with the induction of a variety of cytokines, including tumor necrosis factor-alpha (TNF-alpha) and interleukin-1alpha/beta (IL-1alpha/beta) that contributes to stroke injury. Transient middle cerebral artery occlusion (tMCAO) in spon...

journal_title：Brain research

authors： Adibhatla RM,Hatcher JF

更新日期：2007-02-23 00:00:00

abstract：:Although the role of cAMP-response-element-binding protein (CREB) binding protein (CBP) in the neuroprotective mechanisms has been the focus of many studies, very little is known about the expression or function of CBP in aged brains. We have therefore examined age-related changes in CBP expression in the cerebral cor...

journal_title：Brain research

authors： Chung YH,Kim EJ,Shin CM,Joo KM,Kim MJ,Woo HW,Cha CI

更新日期：2002-11-29 00:00:00

abstract：:The aim of this study is to verify whether anatomical changes occur in the brains of chess players. Besides, it is a potential attempt to evaluate diffusion properties along the tracts due to the diverse situations at anatomical level in different locations; moreover, conventional voxel-based analysis (VBA) has alread...

journal_title：Brain research

authors： Zhou S,Jin L,He J,Zeng Q,Wu Y,Cao Z,Feng Y

更新日期：2018-12-01 00:00:00

abstract：:Our previous studies demonstrated that Austrolebias charrua annual fish is an excellent model to study adult brain cell proliferation and neurogenesis due to the presence of active and fast neurogenesis in several regions during its short lifespan. Our main goal was to identify and localize the cells that compose the ...

journal_title：Brain research

authors： Torres-Pérez M,Rosillo JC,Berrosteguieta I,Olivera-Bravo S,Casanova G,García-Verdugo JM,Fernández AS

更新日期：2017-10-15 00:00:00

abstract：:In alert cats, extracellular spikes of neurons in the medial pontine tegmentum were recorded simultaneously with whole nerve discharges of the abducens and medial rectus nerves during horizontal vestibular nystagmus. Nystagmus-related neurons were classified by their firing patterns in relation to the abrupt cessation...

journal_title：Brain research

authors： Curthoys IS,Nakao S,Markham CH

更新日期：1981-10-05 00:00:00

abstract：:There is evidence that D1 and D2 dopamine receptor subtypes coexist at the cellular level in the striatum and act synergistically to mediate the effects of dopamine. Other data suggest that these receptor subtypes are largely segregated in different striatal projection pathways. We used in situ hybridization in serial...

journal_title：Brain research

authors： Lester J,Fink S,Aronin N,DiFiglia M

更新日期：1993-09-03 00:00:00

abstract：:The involvement of bulbospinal pathways in the antinociceptive effect of clomipramine in experimental pain was studied. The antinociceptive effect of the antidepressant (0.5 mg/kg), intravenously injected, was evaluated after a unilateral lesion of the dorsolateral funiculus. The results showed that this effect was su...

journal_title：Brain research

authors： Ardid D,Jourdan D,Mestre C,Villanueva L,Le Bars D,Eschalier A

更新日期：1995-10-16 00:00:00

abstract：:These experiments examine the dependence of medial hypothalamic alpha 2-receptor binding on the availability of circulating glucose. Food deprivation and tolbutamide-induced hypoglycemia both diminished alpha 2-binding. These binding results were highly correlated with serum glucose levels. Prevention of tolbutamide h...

journal_title：Brain research

authors： Chafetz MD,Parko K,Diaz S,Leibowitz SF

更新日期：1986-10-08 00:00:00

abstract：:The effects of retinoic acid (RA), a naturally occurring metabolite of vitamin A, on the growth, morphology and neurochemical differentiation of the PC12 clone of rat pheochromocytoma cells were investigated. RA added to the medium inhibited the growth of PC12 cells in a dose-dependent manner up to 10 microM without a...

journal_title：Brain research

authors： Matsuoka I,Mizuno N,Kurihara K

更新日期：1989-11-13 00:00:00

abstract：:The VIIIth cranial nerve projections in the hagfish, which has only one circular canal in the ear, were studied by transganglionic HRP transport. This nerve has two branches, the nervus utricularis (N. utr.) and the nervus saccularis (N. sac.), each with its own ganglion, the ganglion utriculare (G. utr.) and the gang...

journal_title：Brain research

authors： Amemiya F,Kishida R,Goris RC,Onishi H,Kusunoki T

更新日期：1985-06-24 00:00:00

abstract：:Diazoxide (DZ), a highly selective opener of the mitochondrial ATP-sensitive potassium (mitoK(ATP)) channel, has neuroprotective effects. However, the mechanism of DZ protecting hippocampal neurons against cell death in pilocarpine-induced seizures is unknown. In this study, we investigated DZ attenuating neuronal los...

journal_title：Brain research

authors： Xue Y,Xie N,Lin Y,Xu J,Han Y,Wang S,Jiang H,Chi Z

更新日期：2011-04-06 00:00:00

abstract：:Inbred mouse strains differed significantly in sensitivity to convulsions induced by 9 convulsant drugs administered using a timed infusion procedure. Some strains (e.g. BALB/cJ, A/J) were generally seizure-susceptible, while some were generally seizure resistant (e.g. C57BL/6J, SWR/J). However, the overall pattern of...

journal_title：Brain research

authors： Kosobud AE,Crabbe JC

更新日期：1990-08-27 00:00:00

abstract：:The effect of an extended program of perforant path or amygdala kindling on paired-pulse suppression in the dentate gyrus was studied in male hooded rats. Repeated kindling stimulations were delivered twice or three times daily until either 300 stimuli had been delivered or generalized convulsions had been observed to...

journal_title：Brain research

authors： Milgram NW,Michael M,Cammisuli S,Head E,Ferbinteanu J,Reid C,Murphy MP,Racine R

更新日期：1995-01-23 00:00:00

abstract：:An extensive exploration of the discriminating properties of olfactory receptors cells has been conducted in our laboratory through the statistical processing of single cell responses recorded in the frog's olfactory epithelium. Similarities between odorant stimulating properties could be demonstrated by comparing the...

journal_title：Brain research

authors： Sicard G,Holley A

更新日期：1984-02-06 00:00:00

abstract：:Experiments were performed which demonstrate that low power, pulsed microwave exposure induces a significant increase in local cerebral blood flow within the brain of the conscious rat. Previous studies purporting to examine changes in brain vascular permeability induced by microwave radiation must be re-evaluated in ...

journal_title：Brain research

authors： Oscar KJ,Gruenau SP,Folker MT,Rapoport SI

更新日期：1981-01-05 00:00:00