Involvement of bulbospinal pathways in the antinociceptive effect of clomipramine in the rat.

abstract：:Bombesin (BN)- and substance P (SP)-containing neurons are found in the dorsal root ganglia, and project to the dorsal horn of the spinal cord. The present study was undertaken to determine if chronic deafferentation of the cat spinal cord would affect BN or SP receptors in the spinal cord. Ten and 30 days after a uni...

journal_title：Brain research

authors： Massari VJ,Shults CW,Park CH,Tizabi Y,Moody TW,Chronwall BM,Culver M,Chase TN

更新日期：1985-09-23 00:00:00

abstract：:Region-specific noradrenergic inputs to the bed nuclei of the stria terminalis (BST) from the caudal medulla were studied using combined Fast Blue injections and tyrosine hydroxylase immunoreactivity (TH-ir). Injections into the rostral, dorsal, ventral and lateral BST resulted in predominantly ipsilateral retrograde ...

journal_title：Brain research

authors： Terenzi MG,Ingram CD

更新日期：1995-02-20 00:00:00

abstract：:The basic characteristics of the electroencephalograms (EEGs) of the entorhinal cortex (EC) were compared to those of the olfactory bulb (OB) and prepiriform cortex (PPC) in the awake cat, using methods that take into account linear (coherence functions) and non-linear relationships (mutual information). The frequency...

journal_title：Brain research

authors： Boeijinga PH,Lopes da Silva FH

更新日期：1988-05-17 00:00:00

abstract：:Our previous study reported that cathepsin L may contribute to the death of dopaminergic neurons in rodent model of Parkinson's disease (PD). In this study we detected the changes in the expression of lysosomal cathepsin L in cellular models of PD. In human neuroblastoma SH-SY5Y cells, treatment with 6-hydroxydopamine...

journal_title：Brain research

authors： Xiang B,Fei X,Zhuang W,Fang Y,Qin Z,Liang Z

更新日期：2011-04-28 00:00:00

abstract：:Detailed quantitative information on catecholamines and 5-hydroxytryptamine (serotonin) in the human thalamus is much needed because of increasing interest in norepinephrine and serotonin as modulators of thalamic behavioral state control and overall information processing. This study provides three-dimensional distri...

journal_title：Brain research

authors： Oke AF,Carver LA,Gouvion CM,Adams RN

更新日期：1997-07-18 00:00:00

abstract：:Opioid-binding cell adhesion molecule (OBCAM) is the member of the IgLON family, a subgroup of the immunoglobulin superfamily. In the present study, the functions and dynamics of OBCAM were investigated in hippocampal neurons in vitro. Western blotting revealed that OBCAM expression was low at early stages of culture ...

journal_title：Brain research

authors： Yamada M,Hashimoto T,Hayashi N,Higuchi M,Murakami A,Nakashima T,Maekawa S,Miyata S

更新日期：2007-08-24 00:00:00

abstract：:Parvalbumin (PV) and calbindin (CB) immunoreactivities were assessed in nucleus robustus archistriatalis (RA) of male and female zebra finches, together with retrograde labelling of RA neurons. The results of double and triple labelling experiments suggested that, in males, moderately and faintly PV-positive neurons w...

journal_title：Brain research

authors： Wild JM,Williams MN,Suthers RA

更新日期：2001-11-02 00:00:00

abstract：:Polyamines play critical roles during the development of brain neurons. In the present study we examined the effects of polyamines on neuronal apoptotic death. Rat cerebellar granule neurons were cultured in the presence of a depolarizing concentration of KCl (25 mM) in the medium. Apoptotic neuronal death was induced...

journal_title：Brain research

authors： Harada J,Sugimoto M

更新日期：1997-04-11 00:00:00

abstract：:After traumatic brain injury, extracellular K(+) in brain can dramatically increase. We studied the effects of increased K(+) on the isolated pressurized rat middle cerebral artery (MCA). MCAs (200-250 microm OD) were isolated, cannulated with glass micropipettes, and pressurized. K(+) was increased in the extralumina...

journal_title：Brain research

authors： Golding EM,Steenberg ML,Johnson TD,Bryan RM Jr

更新日期：2000-10-13 00:00:00

abstract：:Appetite suppressants lose efficacy when given chronically; the mechanisms are unknown. We gave male rats once-daily dl-fenfluramine (dl-FEN, 5 mg/kg, i.p.) injections for 15 days and measured mRNA expression of corticotropin releasing factor (CRF), neuropeptide Y (NPY) and proopiomelanocortin (POMC) in hypothalamic n...

journal_title：Brain research

authors： Choi S,Blake V,Cole S,Fernstrom JD

更新日期：2006-05-04 00:00:00

abstract：:The primary objective of this study was to test the hypothesis that intravenous administration of autologous bone marrow cells could improve functional recovery after middle cerebral artery occlusion (MCAO) for 45 min in the rat and to determine specific time windows for efficacy. Mononuclear cells from autologous bon...

journal_title：Brain research

authors： Iihoshi S,Honmou O,Houkin K,Hashi K,Kocsis JD

更新日期：2004-05-08 00:00:00

abstract：:The pattern of generation of neurons in the albino rat superior colliculus has been studied in adult and fetal material. Neurons are generated between embryonic days 12 to 17, with rostrolateral colliculus in advance of caudomedial parts. More of the cells contributing to the deeper layers are generated early, while m...

journal_title：Brain research

authors： Mustari MJ,Lund RD,Graubard K

更新日期：1979-03-23 00:00:00

abstract：:Small reductions in temperature have been shown to improve neurologic recovery after ischemia. We have examined the effect of temperature on biochemical and physiological changes during hypoxia using rat hippocampal slices as a model system. The postsynaptic population spike recorded from the CA1 pyramidal cell region...

journal_title：Brain research

authors： Amorim P,Cottrell JE,Kass IS

更新日期：1999-10-09 00:00:00

abstract：:Endogenous calcitonin was altered in rats by thyroparathyroidectomy, followed by supplementation with thyroxine and calcium. As a result, a reduction in the content of 5-hydroxytryptamine in the brain together with an increase in the concentration of tryptophan in the plasma were observed. The changes were accompanied...

journal_title：Brain research

authors： Nakhla AM,Latif A

更新日期：1982-04-29 00:00:00

abstract：:The effects of two drugs with anxiolytic actions, diazepam (0.1, 0.3 and 1 mg/kg) and nicotine (0.1 and 0.5 mg/kg) were examined on the time spent in social interaction by pairs of male gerbils. In a test arena lit by high light, diazepam (0.1 mg/kg) increased social interaction, without changing locomotor activity. D...

journal_title：Brain research

authors： File SE,Cheeta S,Akanezi C

更新日期：2001-01-12 00:00:00

abstract：:Brief applications of high glycine concentrations to hippocampal slices have been shown to produce long-lasting changes in synaptic efficacy. In the present study, we show that glycine application transiently and reversibly increases the amplitude and prolongs the duration of synaptic potentials mediated by N-methyl-D...

journal_title：Brain research

authors： Shahi K,Baudry M

更新日期：1993-11-12 00:00:00

abstract：:Despite a blood-brain barrier for norepinephrine, the concentration of norepinephrine in plasma and cerebrospinal fluid has been observed to be similar. This relationship between plasma and cerebrospinal fluid norepinephrine levels suggest that peripheral sympathetic neurons innervating blood vessels to brain and spin...

journal_title：Brain research

authors： Peskind ER,Raskind MA,Wilkinson CW,Flatness DE,Halter JB

更新日期：1986-03-05 00:00:00

abstract：:Cholinergic systems modulate synaptic transmission across the neuraxis and play an important role in higher brain function including cognition, arousal and nociception. The anterior cingulate cortex (ACC) is a fundamental brain region for nociception and chronic pain, and receives cholinergic projections mainly from b...

journal_title：Brain research

authors： Koga K,Matsuzaki Y,Migita K,Shimoyama S,Eto F,Nakagawa T,Matsumoto T,Terada K,Mishima K,Furue H,Honda K

更新日期：2019-02-01 00:00:00

abstract：:Coated vesicles within dentate gyrus granule cell dendrites were found free in the cytoplasm and also attached to the smooth endoplasmic reticulum and plasmalemma. Coated vesicles began increasing in number 40-48 h following partial dendritic deafferentation. This increase continued up to 15-30 days postlesion, after ...

journal_title：Brain research

authors： McWilliams JR,Lynch G

更新日期：1981-04-27 00:00:00

abstract：:The discontinuous terminal distributions of thalamo- and nigrostriatal axons were examined in adjacent tissue sections from single cat brains by combined anterograde labeling with tritiated proline autoradiography and wheat germ-horseradish peroxidase histochemistry. Injection of one tracer into the centromedian-paraf...

journal_title：Brain research

authors： Beckstead RM

更新日期：1985-05-27 00:00:00

abstract：:Angiotensin converting enzyme (ACE) is Zn2+ metallopeptidase which plays an important role in blood pressure homeostasis in mammals and other vertebrates. Homologues of ACE involved in the biosynthesis of mammalian peptide hormones have also been identified in the insects, Musca domestica, Drosophila melanogaster and ...

journal_title：Brain research

authors： Schoofs L,Veelaert D,De Loof A,Huybrechts R,Isaac E

更新日期：1998-03-02 00:00:00

abstract：:Endoplasmic reticulum (ER) and mitochondria dysfunction contribute to insulin resistance generation during obesity and diabetes. ER and mitochondria interact through Mitofusin 2 (MTF2), which anchors in the outer mitochondrial and ER membranes regulating energy metabolism. Ablation of MTF2 leads to ER stress activatio...

journal_title：Brain research

authors： Diaz B,Fuentes-Mera L,Tovar A,Montiel T,Massieu L,Martínez-Rodríguez HG,Camacho A

更新日期：2015-11-19 00:00:00

abstract：:Intraventricular administration of cholecystokinin-octapeptide in unanesthetized rats results in a significant reduction in the number of [3H]spiperone binding sites. Striatal levels of the dopamine metabolites 3,4-dihydroxyphenylacetic acid and homovanillic acid were significantly reduced, whereas there was no signif...

journal_title：Brain research

authors： Mashal RD,Owen F,Deakin JF,Poulter M

更新日期：1983-10-31 00:00:00

abstract：:The amygdala has long been implicated in conditioned fear. The mesencephalic dopaminergic system provides a rich innervation to the amygdala [J.H. Fallon, P. Ciofi, Distribution of monoamines within the amygdala, in: J.P. Aggleton (Ed.), The Amygdala: Neurobiological Aspects of Emotion, Memory and Mental Dysfunction, ...

journal_title：Brain research

authors： Guarraci FA,Frohardt RJ,Kapp BS

更新日期：1999-05-08 00:00:00

abstract：:Fasting induced a reduction in neuronal nitric oxide synthase (nNOS) mRNA in the paraventricular nucleus (PVN) and supraoptic nucleus (SON) of rats. The effect of intracerebroventricular (i.c.v.) administration of leptin on the nNOS mRNA level in the PVN and SON of fasting rats was studied by in situ hybridization his...

journal_title：Brain research

authors： Isse T,Ueta Y,Serino R,Noguchi J,Yamamoto Y,Nomura M,Shibuya I,Lightman SL,Yamashita H

更新日期：1999-11-06 00:00:00

abstract：:The aim of this study was to test the hypothesis that ATP elevates cytosolic free Ca2+ levels ([Ca2+]i) in myenteric neurons expressing the Ca2+ binding protein, calbindin-D28. A laser microbeam marked the location of cultured neurons on coverslips and provided unequivocal relocation of ATP-responsive neurons after im...

journal_title：Brain research

authors： Christofi FL,Guan Z,Lucas JH,Rosenberg-Schaffer LJ,Stokes BT

更新日期：1996-07-01 00:00:00

abstract：:These studies examined the microsomal brain metabolism of phencyclidine (PCP) in male and female Sprague-Dawley rats. Several monohydroxylated metabolites of PCP were detected including cis- and trans-1-(1-phenyl-4-hydroxycyclohexyl)piperidine (c-PPC and t-PPC) and 1-(1-phenylcyclohexyl)-4-hydroxypiperidine (PCHP). Th...

journal_title：Brain research

authors： Laurenzana EM,Owens SM

更新日期：1997-05-09 00:00:00

abstract：:Using an immunoperoxidase technique, somatostatin-28-like immunoreactive (LIR) neurons were observed in the main and accessory olfactory bulb (MOB and AOB) of adult rats. In the MOB, a restricted population of periglomerular cells in the glomerular layer, some superficial short-axon cells in the juxtaglomerular layer,...

journal_title：Brain research

authors： Takami S,el-Hawary MH,Graziadei PP

更新日期：1990-09-03 00:00:00

abstract：:The purpose of this study was to determine the effects of specific proinflammatory cytokines interleukin-6 (Il-6), interleukin-1beta (Il-1beta), interferon-gamma (IFN), and tumor necrosis factor-alpha (TNFalpha), on content and distribution of alpha-synuclein (alpha-synuclein), tau and ubiquitin in human derived cultu...

journal_title：Brain research

authors： Bick RJ,Poindexter BJ,Kott MM,Liang YA,Dinh K,Kaur B,Bick DL,Doursout MF,Schiess MC

更新日期：2008-06-27 00:00:00

abstract：:During the middle of the subjective day, circadian activity rhythms in Syrian hamsters can be phase advanced by a variety of stimuli including microinjection of neuropeptide Y (NPY) or muscimol into the suprachiasmatic nucleus (SCN). It is not known, however, if these treatments shift activity rhythms by acting direct...

journal_title：Brain research

authors： Huhman KL,Marvel CL,Gillespie CF,Mintz EM,Albers HE

更新日期：1997-10-24 00:00:00