Sprouting in the hippocampus is accompanied by an increase in coated vesicles.

abstract：:Chemotherapy-induced pain is the most common treatment-limiting complication encountered by cancer patients receiving taxane-, vinca alkaloid- or platin-based chemotherapy. Several lines of evidence indicate that activation of pro-inflammatory cascades involving the release of cytokines including tumor necrosis factor...

journal_title：Brain research

authors： Cata JP,Weng HR,Dougherty PM

更新日期：2008-09-10 00:00:00

abstract：OBJECTIVE:To investigate the effect of salvinorin A (SA) on brain injury and neurologic function post-brain ischemia/reperfusion (I/R) using a rat forebrain ischemia model and further explore the effect of kappa opioid receptor (KOR) inhibition by SA on aquaporin-4 (AQP4) expression in the hippocampus, cortex and stria...

journal_title：Brain research

authors： Xin J,Zhang Y,He Z,Wang Z

更新日期：2016-04-15 00:00:00

abstract：:In human brain, regulation of agonist binding to the D2 dopamine receptors by guanine nucleotides is different between several regions. In membranes of the anterior pituitary lobe, agonist binding is fully sensitive to GTP or Gpp(NH)p, whereas it is resistant in membranes of globus pallidus. Both guanine nucleotide-se...

journal_title：Brain research

authors： De Keyser J,Walraevens H,De Backer JP,Ebinger G,Vauquelin G

更新日期：1989-04-10 00:00:00

abstract：:Previous studies in piglets show that opioid-induced pial artery dilation was impaired following fluid percussion brain injury (FPI). This study was designed to determine the role of the newly described opioid nociceptin orphanin FQ (NOC/oFQ) in such impaired dilation to other opioids after FPI. CSF NOC/oFQ concentrat...

journal_title：Brain research

authors： Armstead WM

更新日期：2000-06-30 00:00:00

abstract：:Hydrogen-rich water (HRW) has anti-oxidant activities, and it exerts neuroprotective effects during ischemia-reperfusion brain injury. Parvalbumin and hippocalcin are two calcium buffering proteins, which are involved in neuronal differentiation, maturation and apoptosis. The aim of this study was to investigate wheth...

journal_title：Brain research

authors： Han L,Tian R,Yan H,Pei L,Hou Z,Hao S,Li YV,Tian Q,Liu B,Zhang Q

更新日期：2015-07-30 00:00:00

abstract：:An acute pain animal model for fMRI study would provide useful spatial and temporal information for studying the supraspinal nociceptive neuronal responses. The aim of the present study was to investigate whether the nociceptive responses in different brain areas can be differentiated by using functional magnetic reso...

journal_title：Brain research

authors： Chang C,Shyu BC

更新日期：2001-04-06 00:00:00

abstract：:Pain resulting from peripheral nerve injury, characterised by ongoing pain, hyperalgesia and allodynia arises from peripheral and central processes. Here, we studied the potential role of central facilitations in nerve injury by investigating the effect of blocking the excitatory 5HT3 receptor with ondansetron. 5HT3 r...

journal_title：Brain research

authors： Suzuki R,Rahman W,Hunt SP,Dickenson AH

更新日期：2004-09-03 00:00:00

abstract：:We compared the laminar location and morphology of superior colliculus cells projecting to the dorsal and ventral lateral geniculate nuclei (LGd, LGv), the pretectum (PT), the parabigeminal nucleus (Pb), and nucleus lateralis posterior (LP) in the ground squirrel Spermophilus tridecemlineatus. Horseradish peroxidase w...

journal_title：Brain research

authors： Lugo-Garcia N,Kicliter E

更新日期：1987-11-17 00:00:00

abstract：:Monoclonal antibody N210 (mabN210) recognizes the 210 kdalton neurofilament protein in mammals and gives characteristic immunocytochemical staining of neurofilament-rich processes. For example, in the cerebellum it recognizes myelinated axons and the calyx formed by basket cell axon collaterals. The distribution of ma...

journal_title：Brain research

authors： Maler L,Leclerc N,Hawkes R

更新日期：1986-07-23 00:00:00

abstract：:This work examines the age-related changes of the NO pathway in the central nervous system (CNS), analyzing nitric oxide synthase (NOS) isoform expression, the level of nitrotyrosine-modified proteins, and the NOS activity in the cerebral cortex, decorticated brain (basal ganglia, thalamus, hypothalamus, tegtum and te...

journal_title：Brain research

authors： Siles E,Martínez-Lara E,Cañuelo A,Sánchez M,Hernández R,López-Ramos JC,Del Moral ML,Esteban FJ,Blanco S,Pedrosa JA,Rodrigo J,Peinado MA

更新日期：2002-11-29 00:00:00

abstract：:We have established a cell line (TB) from a cerebrospinal fluid (CSF) specimen of a patient with a primary leptomeningeal melanomatosis. TB cell line was immunoreactive with the antibodies for low molecular weight neurofilament protein, vimentin, neuron-specific enolase, chromogranin, synaptophysin and HMB-45 (an anti...

journal_title：Brain research

authors： Sorrentino G,Monsurrò MR,Pettinato G,Vanni R,Zuddas A,Di Porzio U,Bonavita V

更新日期：1999-05-08 00:00:00

abstract：:Long-term potentiation (LTP) consists of an enhanced response to released transmitter by the quisqualate/AMPA subclass of glutamate receptors with little change in the slower currents generated by the NMDA receptor subclass. Recent computer simulations suggest that a decrease in the resistance of dendritic spines woul...

journal_title：Brain research

authors： Larson J,Lynch G

更新日期：1991-01-11 00:00:00

abstract：:The localization of the glycine cleavage system was examined in the rat brain by immunohistochemistry using an antibody to P-protein (a constituent of the system). In all sites studied, the enzyme was confined to the astrocytes. The intensity of astrocyte staining varied in different brain regions, with the strongest ...

journal_title：Brain research

authors： Sato K,Yoshida S,Fujiwara K,Tada K,Tohyama M

更新日期：1991-12-13 00:00:00

abstract：:The intracellular localization of the serine protease plasminogen activator was analyzed in homogenates of bovine brain cortex using differential fractionation procedures. The distribution of the enzyme was clearly different from that of cytosol and mitochondrial markers, and was similar to that of plasma membrane pro...

journal_title：Brain research

authors： Zisapel N,Miskin R,Laudon M,Soreq H

更新日期：1982-09-23 00:00:00

abstract：:We have previously reported that lead (Pb(2+)) exposure results in both presynaptic and postsynaptic changes in developing neurons as a result of inhibition of the N-methyl-d-aspartate receptor (NMDAR). NMDAR inhibition by Pb(2+) during synaptogenesis disrupts downstream trans-synaptic signaling of brain-derived neuro...

journal_title：Brain research

authors： Neal AP,Stansfield KH,Guilarte TR

更新日期：2012-02-23 00:00:00

abstract：:Myelin of several Caudata (Urodela) species appears to be unique in the fact that it lacks hydroxycerebrosides and hydroxysulfatides although it contains their non-hydroxy counterparts. Comparison of the nerve conduction velocities in the Urodeles Necturus (salamander) and Notophthalmus (newt) with that in a reptile, ...

journal_title：Brain research

authors： Ki PF,Kishimoto Y,Lattman EE,Stanley EF,Griffin JW

更新日期：1985-10-14 00:00:00

abstract：:Preconditioning describes a variety of treatments that induce neurons to become more resistant to a subsequent ischemic insult. How preconditioned neurons adapt to subsequent ischemic stress is not fully understood, but is likely to involve multiple protective mechanisms. We hypothesized hypoxic preconditioning induce...

journal_title：Brain research

authors： Arthur PG,Lim SC,Meloni BP,Munns SE,Chan A,Knuckey NW

更新日期：2004-08-13 00:00:00

abstract：:Neurons in the ventromedial tegmental area that project to the rostral part of the dorsal cap of the ipsilateral inferior olive were labeled by the technique of retrograde transport of horseradish peroxidase (HRP). Following iontophoresis of HRP into the rostral part of the dorsal cap a cluster of labeled cells are fo...

journal_title：Brain research

authors： Maekawa K,Takeda T

更新日期：1979-08-31 00:00:00

abstract：:Cajal-Retzius (CR) cells of the mammalian neocortex co-express the extracellular matrix protein Reelin and p73, a transcription factor involved in cell death and survival. Most neocortical CR cells derive from the cortical hem, with minor additional sources. We analyzed the distribution of Reelin and p73 immunoreactiv...

journal_title：Brain research

authors： Cabrera-Socorro A,Hernandez-Acosta NC,Gonzalez-Gomez M,Meyer G

更新日期：2007-02-09 00:00:00

abstract：:Met5-enkephalin- (Met-ENK), Leu5-enkephalin-, Met5-enkephalin-Arg6-Phe7-, metorphamide- and BAM 22P-like peptides could be detected in the lumbar spinal cord of the chicken by immunocytochemistry and/or high performance liquid chromatography. However, a peptide identical to Met5-enkephalin-Arg6-Gly7-Leu8 could not be ...

journal_title：Brain research

authors： Maderdrut JL,Merchenthaler I,Sundberg DK,Okado N,Oppenheim RW

更新日期：1986-07-02 00:00:00

abstract：:The ontogeny of muscarinic cholinergic receptors was studied in primary cultures of dissociated rat hippocampal cells. The specific [3H]quinuclidinyl benzilate [( 3H]QNB) to intact cells was detected after two days in culture. Scatchard analysis revealed only a unique binding site at all of the days tested, with a ver...

journal_title：Brain research

authors： Fernandez-Tomé P,Segal M

更新日期：1987-09-01 00:00:00

abstract：:Using psychophysical techniques, the ability of human subjects to discriminate the velocity of brush movement across the glabrous skin of the hand was determined. The same stimulus was then used in a series of neurophysiological experiments designed to determine the ability of neurons in the primary somatosensory cort...

journal_title：Brain research

authors： Collins JG,Roppolo JR

更新日期：1980-10-06 00:00:00

abstract：:The principal finding in this study is that the callosal projection to the occipital cortex in rats and mice follows a complex and highly reproducible pattern which has not previously been described in detail. In some regions, the callosal projection is associated with well defined cytoarchitectonic boundaries such as...

journal_title：Brain research

authors： Cusick CG,Lund RD

更新日期：1981-06-15 00:00:00

abstract：:Autoradiographic analysis of [(35)S]GTPgammaS binding was used to investigate functional activation of dopamine receptors in rat striatum. Dopamine-stimulated [(35)S]GTPgammaS binding was observed with a maximal increase of 38% over basal activity. A similar stimulatory response was obtained with the D(2) agonist quin...

journal_title：Brain research

authors： He L,Di Monte DA,Langston JW,Quik M

更新日期：2000-12-01 00:00:00

abstract：:The herpes virus suis has been used as a tracer for the pathways in the central nervous system of the rat. The viruses have been inoculated in various peripheral structures innervated by the trigeminal nerve, namely in the cornea by instillation or scarification, in the anterior chamber of the eye by injection and als...

journal_title：Brain research

authors： Martin X,Dolivo M

更新日期：1983-08-29 00:00:00

abstract：:The VIIIth cranial nerve projections in the hagfish, which has only one circular canal in the ear, were studied by transganglionic HRP transport. This nerve has two branches, the nervus utricularis (N. utr.) and the nervus saccularis (N. sac.), each with its own ganglion, the ganglion utriculare (G. utr.) and the gang...

journal_title：Brain research

authors： Amemiya F,Kishida R,Goris RC,Onishi H,Kusunoki T

更新日期：1985-06-24 00:00:00

abstract：:Hyperactivity of the dopaminergic pathway is thought to contribute to clinical symptoms in the early stages of Huntington's disease (HD). It is suggested to be result of a reduced dopaminergic inhibition by degeneration of medium spiny neurons in the striatum. Previously, we have shown that the number of dopaminergic ...

journal_title：Brain research

authors： Huguet G,Temel Y,Kádár E,Pol S,Casaca-Carreira J,Segura-Torres P,Jahanshahi A

更新日期：2019-06-01 00:00:00

abstract：:The neuronal pathology caused by neonatal infection of rats with the PVC-211 murine leukemia virus (PVC-211 MuLV) and its underlying mechanisms are not well defined even though a loss of neurons and spongiform neurodegeneration has been reported to accompany the disease. Here we sought to identify sites of neurodegene...

journal_title：Brain research

authors： Xue QS,Yang C,Hoffman PM,Streit WJ

更新日期：2010-03-10 00:00:00

abstract：:Postnatal development of the K+-stimulated release of [3H]GABA in rat cortex slices was compared to the density of Gray type 2 synapses (which correlate with GABAergic synapses in rat cortex). The [3H]GABA release system develops earlier than the inhibitory synapses which suggests that, at least in the young cortical ...

journal_title：Brain research

authors： Balcar VJ,Dammasch I,Wolff JR

更新日期：1983-11-01 00:00:00

abstract：:Cell transplantation using ventral mesencephalic tissue is an experimental approach to treat Parkinson's disease. This approach is limited by poor survival of the transplants and the high number of dopaminergic neurons needed for grafting. Increasing the yield of dopaminergic neurons in donor tissue is of great import...

journal_title：Brain research

authors： Seiler S,Di Santo S,Sahli S,Andereggen L,Widmer HR

更新日期：2017-08-01 00:00:00