The effects of cholecystokinin on dopaminergic mechanisms in rat striatum.

abstract：:The effects of oligemia (moderate ischemia) on the brain need to be explored because of the potential role of subtle microvascular changes in vascular cognitive impairment and dementia. Chronic bilateral common carotid artery occlusion (BCCAO) in adult rats has been used to study effects of oligemia (hypoperfusion) us...

journal_title：Brain research

authors： Schmidt-Kastner R,Aguirre-Chen C,Saul I,Yick L,Hamasaki D,Busto R,Ginsberg MD

更新日期：2005-08-02 00:00:00

abstract：:In intact guinea pigs a passive horizontal rotation of the body about the fixed head induces compensatory ocular movements (cervico-ocular reflex). When the static neck deviation is maintained, a significant ocular displacement is observed. In acutely hemilabyrinthectomized animals, static body deviation towards the l...

journal_title：Brain research

authors： Pettorossi VE,Petrosini L

更新日期：1984-12-17 00:00:00

abstract：:The activities of 5'-nucleotidase (EC 3.1.3.5) and of 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNP) (EC 3.1.4.37) were measured in crude membrane preparations from 6 brain regions of hypothyroid rats 31 days and 42 days after conception (8-9 days and 19-20 days after birth respectively) and from normal rats 31, 36...

journal_title：Brain research

authors： King RA,Smith RM,Dreosti IE

更新日期：1983-04-01 00:00:00

abstract：:Deltamethrin is a highly potent pyrethroid insecticide that causes hypersensitivity, choreoathetosis, tremors, and paralysis in mammals. It is known to modify the sodium channel in such a way as to prolong the tail current associated with step repolarization following a depolarizing pulse. Using the axial-wire voltage...

journal_title：Brain research

authors： Brown LD,Narahashi T

更新日期：1992-07-03 00:00:00

abstract：:Experiments were performed in pigeons (Columba livia). Sympathetic preganglionic neurons (SPNs) in the first thoracic spinal cord segment (T1) were identified electrophysiologically using antidromic activation and collision techniques and then intracellularly labeled with horseradish peroxidase (HRP). In 6 of 10 HRP-l...

journal_title：Brain research

authors： Bogan N,Cabot JB

更新日期：1991-02-15 00:00:00

abstract：:Microinjection of apomorphine into the ventral tegmental area (VTA) of male rats was previously shown to delay the onset of copulation and slow its rate, presumably by stimulating impulse-regulating autoreceptors on cell bodies of the A10 mesocorticolimbic dopamine tract. Such stimulation would be expected to slow the...

journal_title：Brain research

authors： Hull EM,Weber MS,Eaton RC,Dua R,Markowski VP,Lumley L,Moses J

更新日期：1991-07-19 00:00:00

abstract：:Brain and anterior pituitary growth hormone (GH), thyroid-stimulating hormone (TSH) and luteinizing hormone (LH) were measured during fetal, neonatal, and pubertal life and into adulthood. Immunoassayable GH and TSH could be found in the fetal whole brain before their detection in the fetal pituitary. Developmental pa...

journal_title：Brain research

authors： Hojvat S,Emanuele N,Baker G,Connick E,Kirsteins L,Lawrence AM

更新日期：1982-08-01 00:00:00

abstract：:Venous capacitance plays an important role in the control of cardiac output. However, the central nervous system sites and neurochemical signals involved in modulating venous function remain to be fully elucidated. The hypothalamic paraventricular nucleus (PVN) is an important site modulating autonomic outflow to the ...

journal_title：Brain research

authors： Martin DS,Rodrigo MC,Egland MC,Barnes LU

更新日期：1997-05-09 00:00:00

abstract：:Corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) are pivotal mediators of the hormonal response to stressors and are found within neurons of the paraventricular nucleus of the hypothalamus (PVN) and several extrahypothalamic sites where expression is activity-dependent. Previous work has shown incr...

journal_title：Brain research

authors： Foradori CD,Lund TD,Nagahara AH,Koenig JI,Handa RJ

更新日期：2007-08-20 00:00:00

abstract：:This study attempted to ascertain whether heatstroke-induced ischemia is associated with augmented striatal glutamate release and can be attenuated by NMDA receptor antagonists. Mean arterial pressure (MAP), striatal cerebral blood flow (CBF), striatal glutamate release and striatal neuronal damage score were assessed...

journal_title：Brain research

authors： Yang YL,Pan WH,Chiu TH,Lin MT

更新日期：1998-06-08 00:00:00

abstract：:Alpha-synuclein is a natively unfolded protein playing a key role in the regulation of several neuronal synaptic functions in physiological and pathological conditions. Many studies, over the past years, have shown that it is actively involved in PD pathophysiology. Alpha-synuclein is integrated in a complex network o...

journal_title：Brain research

authors： Bellucci A,Zaltieri M,Navarria L,Grigoletto J,Missale C,Spano P

更新日期：2012-10-02 00:00:00

abstract：:The nature of the delayed blood-brain barrier (BBB) opening that occurs in rats subjected to forebrain ischemia by the technique of two-vessel (carotid) occlusion plus hypovolemic hypotension (2VO ischemia) was probed by examining the simultaneous, trans-barrier movement of two hydrophilic, normally poorly permeative ...

journal_title：Brain research

authors： Preston E,Foster DO

更新日期：1997-06-27 00:00:00

abstract：:The basal ganglia of rhesus and squirrel monkeys were examined using immunohistochemical techniques with antibodies against the neurotensin-related hexapeptides Lys8-Asn9-Neurotensin(8-13) (LANT6) and Neuromedin N. A high percentage of neurons in both segments of globus pallidus and many large neurons of the striatum ...

journal_title：Brain research

authors： Reiner A

更新日期：1987-09-29 00:00:00

abstract：:Neurons containing immunoreactivity to the endogenous lactose-binding lectin, RL-29, were examined in the L4 segment of the spinal cord of rats with an experimental neuropathy. The cells appeared by 5 days and were also present at 14 and 28 days postoperatively. All neurons were found in the dorsal horn ipsilateral to...

journal_title：Brain research

authors： Cameron AA,Dougherty PM,Garrison CJ,Willis WD,Carlton SM

更新日期：1993-08-20 00:00:00

abstract：:Our previous studies indicated that L-type calcium channel blocker diltiazem could potentiate pentobarbital-induced hypnosis through serotonergic system. In view of the important role of dorsal raphe nucleus (DRN) on the sleep regulation and the pharmacological actions of calcium channel blocker, we presumed that Ca(2...

journal_title：Brain research

authors： Cui SY,Cui XY,Zhang J,Wang ZJ,Yu B,Sheng ZF,Zhang XQ,Shi XL,Zhang YH

更新日期：2011-07-27 00:00:00

abstract：:Methylenedioxymethamphetamine (MDMA, Ecstasy) is a powerful releaser of serotonin. Increasing recreational use of this stimulant and hallucinogenic drug has raised concerns about its potential to produce brain damage. The vast majority of previous research studies have focused on the compound's ability to deplete sero...

journal_title：Brain research

authors： Schmued LC

更新日期：2003-06-06 00:00:00

abstract：:Mounting evidence suggests that sleep loss negatively affects learning and memory processes through disruption of hippocampal function. In the present study, we examined whether sleep loss alters the generation, differentiation, and survival of new cells in the dentate gyrus. Rats were sleep restricted by keeping them...

journal_title：Brain research

authors： Roman V,Van der Borght K,Leemburg SA,Van der Zee EA,Meerlo P

更新日期：2005-12-14 00:00:00

abstract：:Discharges of neurons in the midpontine dorsal tegmental field (DTF neurons) were recorded and analyzed during locomotion and were compared with those of reticulospinal neurons (RS neurons) located lateral to the DTF area. The conduction velocity of the descending axon of the DTF neurons was significantly smaller than...

journal_title：Brain research

authors： Kawahara K,Mori S,Tomiyama T,Kanaya T

更新日期：1985-08-26 00:00:00

abstract：:We utilized proton magnetic resonance spectroscopy to evaluate the metabolic profile of the hippocampus and anterior cingulate cortex of the developing rat brain from postnatal days 14-70. Measured metabolite concentrations were modeled using linear, exponential, or logarithmic functions and the time point at which th...

journal_title：Brain research

authors： Ramu J,Konak T,Liachenko S

更新日期：2016-11-15 00:00:00

abstract：:Recently, this laboratory provided evidence that interleukin-1beta (IL-1beta), an immune and brain-derived cytokine, microinjected into the medial hypothalamus, potentiates defensive rage behavior in the cat elicited from the midbrain periaqueductal gray (PAG), and that such effects are blocked by a 5-HT2 receptor ant...

journal_title：Brain research

authors： Hassanain M,Bhatt S,Zalcman S,Siegel A

更新日期：2005-06-28 00:00:00

abstract：:A novel and convenient assay was used to determine the effect of recombinant Interleukin-2 (IL-2) on the function of the blood-brain barrier (BBB). The assay is based on a variant of the West Nile virus, WN-25, which had lost its neuroinvasiveness but not its neurovirulence. WN-25, when injected intravenously, can cau...

journal_title：Brain research

authors： Kobiler D,Lustig S,Gozes Y,Ben-Nathan D,Akov Y

更新日期：1989-09-04 00:00:00

abstract：:Humans flexibly adapt their behavior using feedback from their environment. This ability is impaired in old age, but recent research suggests this mainly concerns processing of negative feedback and that positive feedback might be spared. The aim of this study was to test this idea of an age-related positivity bias ag...

journal_title：Brain research

authors： Ferdinand NK

更新日期：2019-08-15 00:00:00

abstract：:The suprachiasmatic nucleus of the hypothalamus receives dense serotonergic projections from the raphe nuclei. This input may be involved in the transmission of photic information with activation of 5-HT receptors at night having a photo-mimetic effect. 5-HT2C receptors have been implicated in this role, with 5-HT2C r...

journal_title：Brain research

authors： Varcoe TJ,Kennaway DJ

更新日期：2008-05-13 00:00:00

abstract：:We have previously reported progressive reactive astrocytes in the cerebellum of taiep rats, one of the most regions affected by demyelination, and activation of cerebellar glial cells in vitro. Based on the hypothesis that activated glial cells produce high levels of reactive nitrogen intermediates, we assessed the p...

journal_title：Brain research

authors： Leon-Chavez BA,Aguilar-Alonso P,Gonzalez-Barrios JA,Eguibar JR,Ugarte A,Brambila E,Ruiz-Arguelles A,Martinez-Fong D

更新日期：2006-11-22 00:00:00

abstract：:The effects of dexmedetomidine, a highly selective alpha(2)-adrenoceptor agonist, on extracellular dopamine (DA) concentrations in the nucleus accumbens of awake rats were collected via in vivo cerebral microdialysis and measured using HPLC with electrochemical detection. The administration of dexmedetomidine (DEX) at...

journal_title：Brain research

authors： Whittington RA,Virag L,Morishima HO,Vulliemoz Y

更新日期：2001-11-16 00:00:00

abstract：:Glycans are components of glycoconjugates and function in odorant recognition and cell signaling in the olfactory mucosa. However, little is known about glycan expression in the olfactory mucosa in the presence of neuroinflammatory disorders, which can influence olfaction. We evaluated the changes in glycan in the olf...

journal_title：Brain research

authors： Park C,Kim J,Ahn M,Choi Y,Shin T

更新日期：2020-04-01 00:00:00

abstract：:Obesity and related metabolic disorders are important side effects of some antipsychotic drugs (APs). The currently available animal model of AP-induced bodyweight gain (BWG) in rats is based on administration of sulpiride (SUL). However, this model has important limitations. For example, SUL is a pure dopamine antago...

journal_title：Brain research

authors： Baptista T,Araujo de Baptista E,Ying Kin NM,Beaulieu S,Walker D,Joober R,Lalonde J,Richard D

更新日期：2002-12-06 00:00:00

abstract：:The effects of target and non-target cells on the growth and function of intrastriatal grafts of mesencephalic dopamine neurons have been studied in rats with unilateral 6-hydroxydopamine-induced lesions of the nigrostriatal dopamine pathway. Cell suspensions of ventral mesencephalon from 14-15-day-old rat fetuses (ri...

journal_title：Brain research

authors： Brundin P,Isacson O,Gage FH,Björklund A

更新日期：1986-01-01 00:00:00

abstract：:Voltage-gated potassium (Kv) channels are essential components of neuronal excitability. The Kv3.4 channel protein is widely distributed throughout the central nervous system (CNS), where it can form heteromeric or homomeric Kv3 channels. Electrophysiological studies reported here highlight a functional role for this ...

journal_title：Brain research

authors： Dallas ML,Morris NP,Lewis DI,Deuchars SA,Deuchars J

更新日期：2008-01-16 00:00:00

abstract：:Field potentials and radial current source-densities (CSDs) evoked by optic tract stimulation were observed in goldfish tectum in vitro. The effects of different concentrations of calcium and magnesium were studied to improve understanding of component events in retinotectal transmission and interpretations of effects...

journal_title：Brain research

authors： Langdon RB,Manis PB,Freeman JA

更新日期：1988-02-16 00:00:00