Abstract:
:Following transection of a peripheral nerve in mice, a newly synthesized neurotropic pyrimidine compound, MS-818 was administered intraperitoneally at a dose of 1 mg kg-1 b.wt. day-1. The film model experiments for analyzing the early growth of axonal regeneration suggested that MS-818 activated Schwann cells which migrate from the proximal stump, inducing axonal elongation in vivo.
journal_name
Brain Resjournal_title
Brain researchauthors
Torigoe K,Awaya Adoi
10.1016/s0006-8993(97)01491-1subject
Has Abstractpub_date
1998-03-23 00:00:00pages
337-40issue
2eissn
0006-8993issn
1872-6240pii
S0006-8993(97)01491-1journal_volume
787pub_type
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