Abstract：
:The ability of embryonic tissue to survive cross-transplantation between histologically incompatible rat strains was examined by transplanting septal neurons from Sprague Dawley fetuses to adult Wistar rats (Ag-B6 to Ag-B2 histocompatibility haplotype). Transplants were found to survive without rejection over a period of 3 months. Furthermore, the laminar pattern of cholinergic innervation was similar to that of homogenic septal transplants and of intrinsic septal projections. These results suggest that embryonic neural tissue transplanted across major histocompatibility barriers are capable of survival for extended periods of time, and are in support of the concept of the privileged nature of embryonic tissue as a source of material for cross-transplantation.
journal_name
Brain Resjournal_title
Brain researchauthors
Low WC,Lewis PR,Terri STdoi
10.1016/0006-8993(83)91028-4subject
Has Abstractpub_date
1983-03-07 00:00:00pages
328-33issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(83)91028-4journal_volume
262pub_type
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