Abstract:
:Both nictitating membrane extension and eyelid EMG activity were measured during classical conditioning of rabbits to tone-airpuff pairings. Both measures were highly correlated. Over trials, learning criterion was met earlier with eyelid EMG activity than with nictitating membrane extension. Within a trial, eyelid EMG preceded and was more robust than nictitating membrane extension. The rabbits were lesioned in the cerebellar interpositus nucleus and then trained for up to 26 days. Detailed analyses of tone alone trials demonstrate that the lesion abolished conditioned responses for both measures. These data confirm that conditioned responses are abolished by lesion of the cerebellar interpositus nucleus.
journal_name
Brain Resjournal_title
Brain researchauthors
Lavond DG,Logan CG,Sohn JH,Garner WD,Kanzawa SAdoi
10.1016/0006-8993(90)91419-hsubject
Has Abstractpub_date
1990-04-30 00:00:00pages
238-48issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(90)91419-Hjournal_volume
514pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::During normal aging, men experience a significant decline in testosterone levels and a compensatory elevation in levels of gonadotropin luteinizing hormone (LH). Both low testosterone and elevated LH have been identified as significant risk factors for the development of Alzheimer's disease (AD) in men. It is unclear ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2012.05.011
更新日期:2012-07-23 00:00:00
abstract::Systemic administration of kainic acid in the rat results in the development of a characteristic excitotoxic syndrome, consisting of automatisms (wet dog shakes, WDS), sustained limbic seizures and brain damage. Since kainate increases the release of excitatory amino acid neurotransmitters such as glutamate, this synd...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)90227-5
更新日期:1994-08-01 00:00:00
abstract::Biochemical analysis of the binding of [125I]Bolton-Hunter coupled substance P [( 125I]BH-SP) to slide-mounted sections of rat brain demonstrated that [125I]BH-SP labels a binding site with a structure-activity profile characteristic of a substance P receptor. Under optimized preincubation and incubation conditions, t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)91009-6
更新日期:1984-08-20 00:00:00
abstract::Postsynaptic potentials evoked in motoneurons innervating m. posterior biceps and semitendinosus (PBSt) and m. triceps surae (GS) by low threshold afferents from various tail muscles located at the level of the second-third caudal vertebrae were investigated in the non-anesthetized and spinalized cat. Afferent inputs ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00039-0
更新日期:1998-03-30 00:00:00
abstract::GEC1 protein shares high identity with GABARAP (GABA(A) Receptor-Associated Protein), interacts with tubulin and GABA(A) receptors and is potentially involved in intracellular transport processes. Recently, using quantitative real time PCR, we have reported the gec1 mRNA expression in different rat brain areas. In the...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2008.02.077
更新日期:2008-05-19 00:00:00
abstract::To better understand the contributions of effort on cortical activation associated with motor tasks, healthy participants with varying capacities for isolating the control of individual finger movements performed tasks consisting of a single concurrent abduction of all digits (Easy) and paired finger abduction with di...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2009.09.005
更新日期:2009-12-08 00:00:00
abstract::Chemotherapy is an effective treatment but difficult to tolerate due to side effects like vomiting. Studies on the etiology of chemotherapy-related emesis have implicated brainstem nuclei and the neurotransmitter substance P, among other substrates. Since rodents do not vomit, other species have been necessary as alte...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.04.061
更新日期:2007-07-02 00:00:00
abstract::Superfusion of slices of the dorsal zone of the lumbar enlargement with an artificial cerebrospinal fluid was used to investigate the possible modulation by GABA receptor ligands of the in vitro release of calcitonin gene-related peptide- and substance P-like materials (CGRPLM and SPLM) from the rat spinal cord. Where...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(10)80048-4
更新日期:1992-06-26 00:00:00
abstract::Although extracellular matrix (ECM) glycoproteins play important roles in neural development, their levels are generally believed to decrease in the adult brain. Immunohistochemical analysis indicates that the anti-adhesive ECM glycoprotein SPARC/osteonectin, which contains a follistatin 'module,' is expressed in the ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00101-u
更新日期:1995-04-03 00:00:00
abstract::Intracellular Neurobiotin-injections were used to label functionally identified neurons in the rostro-dorsomedial part of the trigeminal oral nucleus (Vo.r) in the cat. The labeled Vo.r neurons with the mechanoreceptive field in oral tissues innervated bilaterally either jaw-opening motoneurons or jaw-closing motoneur...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2004.12.042
更新日期:2005-03-02 00:00:00
abstract::The neural connections from the ventral pallidum (VP) through the mediodorsal nucleus of the thalamus (MD) to the medial prefrontal cortex (MPC) were investigated. Extracellular recordings were made from 219 neurons in the medial and lateral portions of the MD and the VP and the MPC were stimulated. The most frequent ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90811-x
更新日期:1985-10-07 00:00:00
abstract::Stroke is the major cause of acquired epilepsy in the adult population. The mechanisms of ischemia-induced epileptogenesis are not completely understood, but glutamate is associated with both ischemia-induced injury and epileptogenesis. The objective of this study was to develop an in vitro model of epileptogenesis in...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.11.065
更新日期:2011-01-31 00:00:00
abstract::In decerebrate cats, the extracellular activities of neurons in the medial medullary reticular formation were studied during constant velocity off-vertical axis rotations (OVAR) in the clockwise (CW) and counterclockwise (CCW) directions (at 10 degrees tilt). Spontaneously active neurons demonstrated sinusoidal positi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00516-1
更新日期:1996-09-02 00:00:00
abstract::Rabbits reared from birth in stroboscopic illumination have no experience of visual motion. In primary visual cortex of these animals there is a large reduction in the number of cells which are direction selective. This result, contrary to previous reports, shows that the rabbit visual system can be modified by early ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(81)90099-7
更新日期:1981-01-01 00:00:00
abstract::Granule cell progenitors in the dentate gyrus of the hippocampal formation have the unusual capacity to be able to divide in the brains of adult rats and primates. The basal proliferation rate of granule cell progenitors in the adult rat is low compared with development, however, it is possible that this rate may beco...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00030-4
更新日期:1998-04-20 00:00:00
abstract::To test the hypothesis that there is a functional modulation of conventional EEG bands associated with preparatory attention, putative changes in the spontaneous brain rhythms and their associated cerebral sources were addressed. The goals of the present report were, first, to find the brain areas with maximal rhythmi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.06.019
更新日期:2006-08-30 00:00:00
abstract::Developmental alcohol exposure can permanently alter brain structures and produce functional impairments in many aspects of behavior, including learning and memory. This study evaluates the effect of neonatal alcohol exposure on adult neurogenesis in the dentate gyrus of the hippocampus and the implications of such ex...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.07.027
更新日期:2011-09-15 00:00:00
abstract::Brains of reptiles, Caiman crocodilus, were processed by standard immunocytochemical methodology using a polyclonal antibody to gamma-aminobutyric acid (GABA) raised in rabbit and a polyclonal antibody to glutamic acid decarboxylase (GAD) raised in sheep. No GABA(+) or GAD(+) cells or puncta were observed over any tha...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)90068-6
更新日期:1988-08-02 00:00:00
abstract::Several forebrain areas have been shown to project to the parabrachial nucleus (PBN) and exert inhibitory and excitatory influences on taste processing. The neurochemicals by which descending forebrain inputs modulate neural taste-evoked responses remain to be established. This study investigated the existence of soma...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2009.08.038
更新日期:2009-11-17 00:00:00
abstract::Following injection of the acylating reagent N-succinimidyl [3H]propionate into the optic nerve of goldfish, labeled protein appeared in the ipsilateral retina and contralateral tectum in a time-dependent manner. Autoradiography indicated the presence of the labeled material in the neuroplasm of the retinal ganglion c...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)91251-9
更新日期:1983-01-24 00:00:00
abstract::Neurotransmitter effects were studied on in vitro release of immunoreactive somatostatin (SRIF) from slices prepared from several regions of the rat brain: mediobasal hypothalamus (MBH), preoptic anterior hypothalamic area (POA) and amygdaloid complex (AMY). Potassium (K+, 56 mM) stimulated SRIF release in all structu...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90523-0
更新日期:1981-06-29 00:00:00
abstract::A decline in the magnitude of the summated responses evoked by taste solutions began about 1 h following IXth nerve transection. In 41 IXth nerves transected at different lengths we found a linear relationship between the length of the IXth nerve stump remaining attached to the tongue and the time for the taste respon...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91331-1
更新日期:1980-07-21 00:00:00
abstract::Choline supplementation of the maternal diet has long-term facilitative effects on spatial and temporal memory processes in the offspring. To further delineate the impact of early nutritional status on brain and behavior, we examined effects of prenatal-choline availability on hippocampal oscillatory frequency bands i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2008.08.077
更新日期:2008-10-27 00:00:00
abstract::A histochemical stain for cytochrome oxidase (CO) activity was used to examine the maturation of a neurochemical correlate of ON and OFF channels in the retina and dorsal lateral geniculate nucleus (LGN) of the tree shrew. In the adult tree shrew, the CO staining pattern can be used as a histochemical marker of segreg...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(87)90217-3
更新日期:1987-08-01 00:00:00
abstract::[1-14C]Octanoate (OCTO) is rapidly extracted from blood and metabolized by brain. Up to 6 min following an intravenous pulse injection the autoradiographic pattern of brain labeling reflects differences in blood flow and energy metabolism. When animals are given OCTO during visual or somatosensory stimulation the auto...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90486-x
更新日期:1985-06-03 00:00:00
abstract::The effect of cerebellar stimulation on the accommodation of the lens was examined in anesthetized cats. An infrared optometer was used to measure the refractive power of the lens during stimulation of the cerebellum. The area giving responses within latencies shorter than 160 msec and amplitudes larger than 0.15 diop...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(78)90334-7
更新日期:1978-09-29 00:00:00
abstract::This study examined the relationship between the affinity of cholinergic drugs for muscarinic receptor subtypes and their potency in potentiating or inhibiting amphetamine-induced rotation. The ascending nigrostriatal dopaminergic pathway was unilaterally lesioned in male Wistar rats using 6-hydroxydopamine. In these ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(87)80021-5
更新日期:1987-04-28 00:00:00
abstract::The present study evaluated the central effects of beta-funaltrexamine (B-FNA), a non-equilibrium antagonist of mu-opioid receptors and a reversible agonist of kappa-opioid receptors upon food intake in rats under freely-feeding, deprivation and glucoprivic conditions. B-FNA elicited distinct short-term and long-term ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)91828-5
更新日期:1990-12-03 00:00:00
abstract::The present study aimed to determine the kinetics of L-3, 4-dihydroxyphenylalanine (L-DOPA) uptake in an immortalised cell line of rat capillary cerebral endothelial cells (clones RBE 4 and RBE 4B), to define the type of inhibition produced by L-5-hydroxytryptophan (L-5-HTP), 2-aminobicyclo(2,2,1)-heptane-2-carboxylic...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)01387-6
更新日期:1999-05-22 00:00:00
abstract::In the present study, we investigated the possibility that MK-801 (dizocilpine), a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, owes its potent neuroprotective properties to calcium channel blocking ability rather than to its NMDA receptor antagonism. Rat hippocampal slices were exposed to a long hy...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00466-4
更新日期:1995-07-03 00:00:00