Synaptic glomeruli in the nucleus submedius of the rat thalamus.

abstract：:Rd mutant mice are visually blind but they maintain the ability of synchronising their circadian rhythms to the external light-dark cycles. We used immunocytochemical procedures to detect light-induced Fos expression in the rd mice retina. We found that Fos is expressed in the rd retina in an unattenuated pattern thro...

journal_title：Brain research

authors： Huerta JJ,Llamosas MM,Cernuda-Cernuda R,García-Fernández JM

更新日期：1999-07-10 00:00:00

abstract：:We have investigated sensitivity to the conditioned fear procedure of mice is influenced by the genetic deletion of alpha2A adrenoceptors (ARs). We observed a heightened freezing response in the discrete cue memory test in alpha2A AR knockout (alpha2A AR KO) mice and in D79N mice, a transgenic mouse strain with functi...

journal_title：Brain research

authors： Davies MF,Tsui JY,Flannery JA,Li X,DeLorey TM,Hoffman BB

更新日期：2003-10-03 00:00:00

abstract：:Previous lectin-histochemical and immunocytochemical investigations using fixed tissue revealed perineuronal nets as lattice-like accumulations of extracellular matrix proteoglycans at the surface of several types of neurons. In the present study, perineuronal nets in the rat brain were labelled for the first time in ...

journal_title：Brain research

authors： Brückner G,Bringmann A,Köppe G,Härtig W,Brauer K

更新日期：1996-05-13 00:00:00

abstract：:Sites which bind oxytocin and vasopressin with high affinity were detected in the brain and upper spinal cord of 12 human subjects, using in vitro light microscopic autoradiography. Tissue sections were incubated with tritiated vasopressin, tritiated oxytocin or an iodinated oxytocin antagonist. The ligand specificity...

journal_title：Brain research

authors： Loup F,Tribollet E,Dubois-Dauphin M,Dreifuss JJ

更新日期：1991-08-02 00:00:00

abstract：:MabQ155, a monoclonal antibody against synaptophysin, has been used to conduct a light microscopic survey of synaptogenesis in the suprachiasmatic nucleus of the perinatal rat. Synaptophysin is an integral component of synaptic vesicle membranes which is expressed in growth cones and growth cone filopodia as well as i...

journal_title：Brain research

authors： Laemle LK,Repke KB,Hawkes R,Rice FL

更新日期：1991-03-22 00:00:00

abstract：:Traumatic brain injury (TBI) is a major public health problem with long-term neurobehavioral sequela. The evidences have revealed that TBI is a risk factor for later development of neurodegenerative disease and both the single and repetitive brain injury can lead to the neurodegeneration. But whether the effects of ac...

journal_title：Brain research

authors： Gao H,Han Z,Bai R,Huang S,Ge X,Chen F,Lei P

更新日期：2017-02-15 00:00:00

abstract：:The blink reflex consists of an early, pontine R1-component and a late, medullary R2-component. R1 and R2 can be evoked by innocuous stimuli, but only the R2 also by painful heat, suggesting that the R2 is mediated by wide dynamic range neurons (WDR) of the spinal trigeminal nucleus. Remote noxious stimuli suppress th...

journal_title：Brain research

authors： Ellrich J,Treede RD

更新日期：1998-08-24 00:00:00

abstract：:Training can induce significant changes in brain functioning and behavioral performance. One consequence of training is changing the pattern of brain activation. Abacus training is of interest because abacus experts gain the ability to handle digits with unusual speed and accuracy. However, the neural correlates of nu...

journal_title：Brain research

authors： Li Y,Hu Y,Zhao M,Wang Y,Huang J,Chen F

更新日期：2013-11-20 00:00:00

abstract：:Isolated brain capillary endothelial cells contain high activity levels of the blood-brain barrier (BBB) marker enzymes gamma-glutamyltranspeptidase (gamma-GT) and alkaline phosphatase (ALP). In primary culture the activities of these specific enzymes decrease with increasing cell proliferation to a constant low value...

journal_title：Brain research

authors： Meyer J,Mischeck U,Veyhl M,Henzel K,Galla HJ

更新日期：1990-04-30 00:00:00

abstract：:Toxoplasma gondii can cause parasitic encephalitis, a life-threatening infection that predominately occurs in immunocompromised individuals. T. gondii has the ability to invade the brain, but the mechanisms by which this parasite crosses the blood-brain-barrier (BBB) remain incompletely understood. The present study r...

journal_title：Brain research

authors： Harun MSR,Marsh V,Elsaied NA,Webb KF,Elsheikha HM

更新日期：2020-11-01 00:00:00

abstract：:Converging evidence implicates alterations in multiple signaling pathways in the etiology of schizophrenia. Previously, these studies were limited to the analysis of one or a few phosphoproteins at a time. Here, we use a novel kinase array platform to simultaneously investigate the convergence of multiple signaling ca...

journal_title：Brain research

authors： McGuire JL,Hammond JH,Yates SD,Chen D,Haroutunian V,Meador-Woodruff JH,McCullumsmith RE

更新日期：2014-06-03 00:00:00

abstract：:Repeating a stimulus generally leads to a decreased response in neural activity compared to that for novel items. This neural attenuation provides a marker for stimulus-specific perceptual encoding and memory that can be detected using functional magnetic resonance imaging (fMRI). Although previously assumed to occur ...

journal_title：Brain research

authors： Yi DJ,Kelley TA,Marois R,Chun MM

更新日期：2006-03-29 00:00:00

abstract：:In order to determine the origin of the catecholamine innervation of the rat piriform cortex (PC), we combined retrograde transport of the B subunit of the cholera toxin (CTb) with tyrosine hydroxylase (TH) immunohistochemistry. A substantial number of CTb retrogradely labeled cells was found in the parabrachial pigme...

journal_title：Brain research

authors： Datiche F,Cattarelli M

更新日期：1996-02-26 00:00:00

abstract：:The gustatory responses of the Mongolian gerbil were tested with 12 sugar alcohols. The electrophysiological effectiveness of the linear polyols as gustatory stimulants increased as the length of the carbon chain increased from 2 to 5. Six and 7 carbon acyclic polyols were no more effective than the pentitols. By comp...

journal_title：Brain research

authors： Jakinovich W Jr,Oakley B

更新日期：1976-07-16 00:00:00

abstract：:In the adult central nervous system (CNS), GABA and glycine (Gly) are predominant inhibitory neurotransmitters, negatively regulating glutamatergic transmission. In the immature CNS, on the other hand, they act as trophic factors, mediating morphogenesis. In the present study, to investigate their involvement in axona...

journal_title：Brain research

authors： Tatetsu M,Kim J,Kina S,Sunakawa H,Takayama C

更新日期：2012-03-29 00:00:00

abstract：:The present study examined the behavioral effects of dopamine receptor agonists, antagonists, or N-methyl-D-aspartate (NMDA) glutamate receptor antagonist in rats with a unilateral excitotoxic lesion of the globus pallidus (GP). After the unilateral GP lesions were made by injections of the ibotenic acid, drugs were s...

journal_title：Brain research

authors： Miwa H,Nishi K,Fuwa T,Mizuno Y

更新日期：1998-01-19 00:00:00

abstract：:Effects of systemic administration of a single dose (50 mg/kg) of ethosuximide (ESM) on extracellularly recorded thalamic (nucleus centralis lateralis, CL; nucleus reticularis, RE) and cortical neurons and on cortical EEG activity of acute cats, have been studied. In intact animals ESM led to: (a) desynchronization of...

journal_title：Brain research

authors： Pellegrini A,Dossi RC,Dal Pos F,Ermani M,Zanotto L,Testa G

更新日期：1989-09-18 00:00:00

abstract：:We report here that following partial spinal transections in adult lampreys, the fibers of the spinal cords can regenerate and restore some intersegmental coordination to the central pattern generator for locomotion, as tested in the isolated cord preparation. However, the regeneration by this test is not successful i...

journal_title：Brain research

authors： Cohen AH,Baker MT,Dobrov TA

更新日期：1989-09-04 00:00:00

abstract：:Dissociated striatal neurons exhibited increased neurite outgrowth when co-cultured with myenteric plexus explants. Enriched enteric neurons or enriched enteric glia produced a less marked response; non-ganglionic cells had no effect. Increases in striatal neuron and glial cell numbers were seen in all co-cultures. Te...

journal_title：Brain research

authors： Höpker VH,Saffrey MJ,Burnstock G

更新日期：1994-06-20 00:00:00

abstract：:The present experiments showed that there is a cortico-thalamo-cortical projection system in the cat, which originates from the primary visual cortex, relayed by the lateral part of the lateral posterior nucleus of the thalamus, and reaching the medial bank of the lateral suprasylvian visual area. This finding suggest...

journal_title：Brain research

authors： Kato N

更新日期：1990-02-12 00:00:00

abstract：:Cultured cells derived from Tay-Sachs disease (TSD) fetal cerebellum were shown to accumulate GM2 ganglioside when compared with control cultures. In contrast, fibroblasts derived from TSD fetal lung do not contain GM2. GM2 was identified by thin-layer chromatography (TLC) and confirmed by gas-liquid chromatography (G...

journal_title：Brain research

authors： Hoffman LM,Amsterdam D,Schneck L

更新日期：1976-07-23 00:00:00

abstract：:Large neurons in the neostriatum of patients with Alzheimer's disease (AD) and progressive supranuclear palsy (PSP) were investigated topographically, histologically and ultrastructurally. The number of large neurons whose nuclear area is greater than 101 microns2 was uniformly decreased in the neostriatum in PSP, but...

journal_title：Brain research

authors： Oyanagi K,Takahashi H,Wakabayashi K,Ikuta F

更新日期：1991-03-29 00:00:00

abstract：:The aim of this study was to determine the effect of different concentrations of normobaric oxygen (NBO) on neurological function and the expression of caspase-3 and -9 in a rat model of acute cerebral ischaemia. Sprague-Dawley rats (n=120) were randomly divided into four groups (n=30 per group), including 3 groups gi...

journal_title：Brain research

authors： Chen S,Peng H,Rowat A,Gao F,Zhang Z,Wang P,Zhang W,Wang X,Qu L

更新日期：2015-08-27 00:00:00

abstract：:Using the teased fiber recording method, we have compared pathophysiological properties of afferent axons injured in the infraorbital nerve (ION) vs the sciatic nerve in rats. Both myelinated and unmyelinated axons ending in ION neuromas produced much less ongoing discharge than those ending in sciatic nerve neuromas....

journal_title：Brain research

authors： Tal M,Devor M

更新日期：1992-05-01 00:00:00

abstract：:An increase in medial perforant synaptic strength can be observed for hippocampal slices from rats exposed to environmental enrichment. The expression of enhanced synaptic strength exhibits properties similar to long-term potentiation (LTP), a physiological model of memory storage. Similarities include an increase in ...

journal_title：Brain research

authors： Foster TC,Gagne J,Massicotte G

更新日期：1996-10-14 00:00:00

abstract：:The dorsolateral funiculus (DLF) spinal pathway has previously been identified as a major pathway involved in descending modulation of pain. While bilateral lesions of the DLF attenuated systemic morphine analgesia as measured by the tail-flick test, they failed to attenuate analgesia as measured by the formalin test....

journal_title：Brain research

authors： Ryan SM,Watkins LR,Mayer DJ,Maier SF

更新日期：1985-05-13 00:00:00

abstract：:Unilateral injections of 6-hydroxydopamine into the lateral hypothalamus or ventral tegmental area that damage extensively the mesotelencephalic dopaminergic projection result in significant hemispheric asymmetries in autoradiographic labeling after [14C]2-deoxy-D-glucose (2DG) administration. The incorporation of thi...

journal_title：Brain research

authors： Kozlowski MR,Marshall JF

更新日期：1980-09-15 00:00:00

abstract：:Cytochemistry was used to examine the distribution of two pathways of utilization of hydrogen (Type I and Type II H) generated by glucose-6-phosphate dehydrogenase (G6PD) in circumventricular organs (CVOs) and the hypothalamo-neurohypophysial system in cryostat sections of rat brain. Type I H is defined as that portio...

journal_title：Brain research

authors： Summy-Long JY,Salisbury R,Marietta MP,Hartman RD,Weisz J

更新日期：1984-02-27 00:00:00

abstract：:Present study revealed the stimulatory effects of delta opioid receptor on intracellular Ca(2+) concentration ([Ca(2+)](i)) in SH-SY5Y cells. Fura-2 based single cell fluorescence ratio (F345/F380) was used to monitor the fluctuation of [Ca(2+)](i). Application of the selective delta-opioid receptor agonist alone, [D-...

journal_title：Brain research

authors： Chen L,Zou S,Lou X,Kang HG

更新日期：2000-11-03 00:00:00

abstract：:In Alzheimer's disease (AD), there is a loss of presynaptic cholinergic markers in the cerebral cortex, but the nature of cholinergic receptor changes is unclear. In this study, [3H]acetylcholine and [3H]nicotine were used to label nicotinic cholinergic binding sites in cerebral cortical tissues obtained at autopsy fr...

journal_title：Brain research

authors： Whitehouse PJ,Martino AM,Antuono PG,Lowenstein PR,Coyle JT,Price DL,Kellar KJ

更新日期：1986-04-16 00:00:00