Abstract:
:We report here that following partial spinal transections in adult lampreys, the fibers of the spinal cords can regenerate and restore some intersegmental coordination to the central pattern generator for locomotion, as tested in the isolated cord preparation. However, the regeneration by this test is not successful in all animals.
journal_name
Brain Resjournal_title
Brain researchauthors
Cohen AH,Baker MT,Dobrov TAdoi
10.1016/0006-8993(89)91090-1subject
Has Abstractpub_date
1989-09-04 00:00:00pages
368-72issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(89)91090-1journal_volume
496pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::The effect of an extended program of perforant path or amygdala kindling on paired-pulse suppression in the dentate gyrus was studied in male hooded rats. Repeated kindling stimulations were delivered twice or three times daily until either 300 stimuli had been delivered or generalized convulsions had been observed to...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)01277-o
更新日期:1995-01-23 00:00:00
abstract::An effective animal model for elucidating the neurobiological basis of human smoking should simulate important aspects of this behavior. Therefore, a 23 h unlimited access nicotine self-administration model was used to compare inbred Lewis rats, which have a propensity to self-administer drugs of abuse, to inbred Fish...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)03375-3
更新日期:2002-03-15 00:00:00
abstract::Visual spatial orienting of attention towards exogenous cues has been one of the attentional functions considered to be spared in ADHD. Here we present a design in which 60 (30 ADHD) children, age: 10.9±1.4, were asked to covertly orient their attention to one or two (out of four) cued locations, and search for a targ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2012.11.036
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:Empathizing is a specific component of social cognition. Empathizing is also specifically impaired in autism spectrum condition (ASC). These are two dimensions, measurable using the Empathy Quotient (EQ) and the Autism Spectrum Quotient (AQ). ASC also involves strong systemizing, a dimension measured using t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.01.012
更新日期:2006-03-24 00:00:00
abstract::The substantia nigra pars reticulata (SNr) receives both inhibitory GABAergic and excitatory glutamatergic afferents from diverse origins. Ischemic injury to the striatum and/or the globus pallidus causes delayed transneuronal death of the SNr neurons, in the course of which neuronal disinhibition induced by loss of G...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(96)01052-9
更新日期:1996-12-16 00:00:00
abstract::In this study, noradrenergic (NE) terminals in the dorsal raphe were identified by [3H]NE electron microscopic (EM) autoradiography. Lesioning of NE terminals by treatment with the selective catecholamine neurotoxin, 6-hydroxydopamine produced a marked decrease in NE-labelled terminals. [3H]5-HT EM autoradiography of ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90646-6
更新日期:1981-01-05 00:00:00
abstract::We investigated the effects of pituitary adenylate cyclase-activating polypeptide (PACAP38) on cytosolic free calcium ([Ca2+]i) at a single cell level in both type-1 and type-2 cultured rat astrocytes using a calcium-sensitive fluorescent dye, fura-2. Type-1 astrocytes were relatively silent during the 20 min observat...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)90790-0
更新日期:1994-10-31 00:00:00
abstract::Physical activity has been related to antioxidant adaptations, which is associated with health benefits, including those to the nervous system. Additionally, available data suggest exercise and a caloric restriction regimen may reduce both the incidence and severity of neurological disorders. Therefore, our aim was to...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.08.003
更新日期:2011-11-03 00:00:00
abstract::The effect of electrolytic lesion of the paraventricular nucleus of the hypothalamus (PVN) on yawning and penile erection induced by apomorphine, oxytocin and adrenocorticotropic hormone (ACTH1-24) was studied in male rats. In sham-operated rats, apomorphine (50 micrograms/kg s.c.), oxytocin (30 ng i.c.v.), and ACTH1-...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)91305-9
更新日期:1987-09-22 00:00:00
abstract::Previous studies have found that the primary change in the brain of chronic alcoholics is a selective loss of white matter in cerebral hemispheres. It is unknown whether the loss of white matter is due to alcohol-induced degeneration of axons in white matter, and this hypothesis has never been tested. We used a newly ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2004.09.035
更新日期:2004-12-17 00:00:00
abstract::Proechimys, a rodent living in the Amazon region, has shown resistance to developing chronic epilepsy when submitted to different experimental models. Recently, many studies have attributed a potent anticonvulsant action to cannabinoid receptor CB1. This study investigated the distribution and expression of the CB1 re...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.03.031
更新日期:2010-06-04 00:00:00
abstract::Stroke is one of the leading causes of unnatural death and disability. No effective therapy is available. Recombinant human granulocyte colony-stimulating factor (rhG-CSF), as a mobilizing agent for bone marrow stem cells, can promote stem cell mobilization, homing to brain after cerebral ischemia. In the present stud...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.02.140
更新日期:2006-07-07 00:00:00
abstract::The effects of the 8-alpha-amino-ergoline CU 32-085 on central dopamine neuronal systems was investigated. Two h after administration of CU 32-085 a slight increase of dopamine levels was observed in the nucleus caudatus-putamen. Radioligand binding studies in vitro have shown that CU 32-085 has a low affinity for str...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91044-3
更新日期:1985-03-04 00:00:00
abstract::Neuromuscular patterns associated with the development of hindlimb stepping behaviors were studied from birth to postnatal day 60 in normal kittens. Hindlimb muscles were chronically implanted with EMG electrodes at birth to characterize interlimb coordination and intralimb synergies during development of overground a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(88)90084-3
更新日期:1988-01-01 00:00:00
abstract::Receptor subunit composition is believed to play a major role in the synaptic trafficking of AMPA receptors (AMPARs), and thus in activity-dependent synaptic plasticity. To isolate a physiological role of GluA1-containing AMPARs in area CA3 of the hippocampus, pair recordings were performed in organotypic hippocampal ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.11.029
更新日期:2012-01-30 00:00:00
abstract::Recently, cerebral blood flow changes were re-discussed to contribute to tissue protection after preconditioning. In the present study, we demonstrate increased vessel diameters of the leptomeningeal anastomoses after hypoxic preconditioning by visualization of the brain angioarchitecture using the latex perfusion tec...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.07.081
更新日期:2006-10-18 00:00:00
abstract::Electrophysiological characteristics were described for neurons of the parabrachial nucleus (PBN) which receive baroreceptive and somatosensory inputs in the rat. Following focal electrical stimulation in the ipsilateral caudal nucleus of the tractus solitarii (NTS), the firing rates of these neurons were increased in...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91704-5
更新日期:1991-12-06 00:00:00
abstract::Sardinian alcohol non-preferring (sNP) rats, selected for their low ethanol preference and consumption, carry a point mutation (R100Q) in the gene coding for GABA(A) receptor alpha(6) subunit, which becomes more sensitive to diazepam-evoked GABA currents. We performed binding studies in the cerebellum of normal (RR) a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(02)04230-0
更新日期:2003-03-28 00:00:00
abstract::The mechanisms controlling the reorganisation of synaptic inputs to developing skeletal muscle fibres was studied using electrophysiological and histological methods. In the developing rat soleus muscle there is a rapid reduction of polyneuronal innervation between 9 and 12 days. Reducing the local concentration of ca...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(86)90069-6
更新日期:1986-07-01 00:00:00
abstract::Maternal care is crucial for offspring development and licking/grooming patterns can be induced by sensorial, neuroendocrine, and metabolic variations in the CNS. Important brain functions, such as learning and memory, can be influenced by oxidative stress, which can also modulate pathophysiological processes (e.g., d...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2016.11.010
更新日期:2017-01-15 00:00:00
abstract::Three priming injections with the D1/D2 dopamine agonist apomorphine permits a challenge with the D2 agonist quinpirole to elicit robust contralateral rotation and ipsilateral striatal Fos expression in 6-hydroxydopamine lesioned rats. Pretreatment with NMDA glutamate antagonists MK-801 or CPP dose-dependently attenua...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)02086-8
更新日期:2001-04-06 00:00:00
abstract::To facilitate the study of the CaMKIIα function in vivo, a CaMKIIα-GFP transgenic mouse line was generated. Here, our goal is to provide the first neuroanatomical characterization of GFP expression in the CNS of this line of mouse. Overall, CaMKIIα-GFP expression is strong and highly heterogeneous, with the dentate gy...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2013.04.042
更新日期:2013-06-26 00:00:00
abstract::Nasal and temporal microexplants from the retina of the chicken embryo (E6; White Leghorn) were cultured on a collagen gel in the presence of extract from anterior or posterior E18 optic tectum. After 4 days of incubation maximum neurite lengths were measured as a function of protein concentration (1-500 micrograms/ml...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(87)90085-x
更新日期:1987-01-01 00:00:00
abstract::The intracellular localization of the serine protease plasminogen activator was analyzed in homogenates of bovine brain cortex using differential fractionation procedures. The distribution of the enzyme was clearly different from that of cytosol and mitochondrial markers, and was similar to that of plasma membrane pro...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)91154-4
更新日期:1982-09-23 00:00:00
abstract::The non-cholinergic slow excitatory postsynaptic potential (EPSP) in the guinea pig inferior mesenteric ganglion (IMG) is believed to be mediated by substance P (SP). Yet, in ganglia of guinea pigs treated with capsaicin (50, 100, or 350 mg/kg, s.c.), a compound that depletes SP from sensory neurons, slow EPSPs were o...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)90227-0
更新日期:1984-06-11 00:00:00
abstract::The suitability of (3H)DPCPX (8-cyclopentyl-1,3-dipropylxanthine), a xanthine derivative, as an vivo probe for labelling adenosine A1 receptors was studied in rats. [3H]DPCPX (nM) penetrated largely into the brain (0.8% of the injected dose per gram of brain tissue 5 min after injection). Brain concentrations stayed a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)90845-z
更新日期:1992-12-18 00:00:00
abstract::The regional distribution of proline biosynthetic enzymes, ornithine-delta-aminotransferase and delta 1-pyrroline-5-carboxylate reductase, in the rat brain, and basic conditions for proline synthesis from ornithine in rat and chicken brain slices and chicken retinas were investigated. The cerebral regions relating to ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)91022-5
更新日期:1987-06-16 00:00:00
abstract::Intracranial microdialysis was used to measure dopamine (DA) release in the ventrolateral neostriatum of freely moving rats before and after unilateral tactile stimulation was applied to the orofacial region. Several behavioral parameters which have been linked to changes in nigrostriatal DA transmission (scanning, or...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90842-j
更新日期:1991-07-12 00:00:00
abstract::It is now well documented that optogenetics brings to neuroscience a long sought-after foothold to study the causal role of millisecond-scale activity of genetically or anatomically defined populations of neurons. Progress is rapid, and, as evidenced by the work collected in this Special Issue, the possibilities of wh...
journal_title:Brain research
pub_type: 杂志文章,评审
doi:10.1016/j.brainres.2013.01.008
更新日期:2013-05-20 00:00:00
abstract::Proliferative response of astrocytes to unilateral injury of the cerebral hemisphere was investigated in 30-day-old rats using a combination of [3H]thymidine autoradiography and immunocytochemical staining for glial fibrillary acidic protein. At different intervals following injury the animals were injected with [3H]t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90566-0
更新日期:1989-04-24 00:00:00