Abstract:
:The understanding of sentences involves not only the retrieval of the meaning of single words, but the identification of the relation between a verb and its arguments. The way the brain manages to process word meaning and syntactic relations during language comprehension on-line still is a matter of debate. Here we review the different views discussed in the literature and report data from crucial experiments investigating the temporal and neurotopological parameters of different information types encoded in verbs, i.e. word category information, the verb's argument structure information, the verb's selectional restriction and the morphosyntactic information encoded in the verb's inflection. The neurophysiological indices of the processes dealing with these different information types suggest an initial independence of the processing of word category information from other information types as the basis of local phrase structure building, and a later processing stage during which different information types interact. The relative ordering of the subprocesses appears to be universal, whereas the absolute timing of when during later phrases interaction takes places varies as a function of when the relevant information becomes available. Moreover, the neurophysiological indices for non-local dependency relations vary as a function of the morphological richness of the language.
journal_name
Brain Resjournal_title
Brain researchauthors
Friederici AD,Weissenborn Jdoi
10.1016/j.brainres.2006.08.038subject
Has Abstractpub_date
2007-05-18 00:00:00pages
50-8eissn
0006-8993issn
1872-6240pii
S0006-8993(06)02433-4journal_volume
1146pub_type
杂志文章,评审相关文献
BRAIN RESEARCH文献大全abstract::The N400 is an event-related potential (ERP) component that is elicited by semantically meaningful stimuli; one of its defining characteristics is that it is amplified for sentence completions that are semantically unexpected or incongruous with the preceding context. Some prior reports using visual sentence reading p...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.07.099
更新日期:2010-10-08 00:00:00
abstract::This study investigated the effects of morphine microinjection into the nucleus raphe magnus (RMg) on electrically evoked C-fiber activities of convergent neurons in the spinal trigeminal nucleus oralis (Sp5O), in halothane-anesthetized rats. Although the neurons could be depressed by systemic morphine (6 mg/kg, i.v.)...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00659-3
更新日期:1998-08-24 00:00:00
abstract::The organization of corticotectal projections from the medial agranular cortex (AGm), which has been considered to contain rat's frontal eye field, was examined using anterograde and retrograde tracing techniques. When biotinylated dextranamine (BDA) injections were made into the rostral part of the AGm, small numbers...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)02437-4
更新日期:2001-06-08 00:00:00
abstract::The intercollicular pathway of the rat was studied using autoradiographic (ARG) and horseradish peroxidase (HRP) tracing techniques. The HRP experiments demonstrated that the cells of origin of the intertectal pathway were located primarily in the rostral stratum griseum intermediale ( SGI ), stratum album intermedium...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)90848-5
更新日期:1984-05-23 00:00:00
abstract::The behavioural response following infusion of a novel, stable substance P (SP) analogue, DiMe-C7, into the ventral tegmental area (VTA) of rats was characterized and contrasted with the response to an equal dose of the parent compound SP. DiMe-C7 produced a longer-lasting behavioural stimulation than SP as evidenced ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90777-6
更新日期:1982-04-22 00:00:00
abstract::Studies were undertaken to characterize the binding of [3H]estradiol ([3H]E2) to blood plasma and to brain cytosols collected from perinatal ferrets of both sexes. A dialysis experiment showed that the binding capacity of plasma for [3H]E2 was low in neonatal ferrets. Saturable, high-affinity binding of [3H]E2 to cyto...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(83)90075-5
更新日期:1983-03-01 00:00:00
abstract::The purpose of this study was to determine whether treatment with high-dose human serum albumin (HSA) would offer protection in a model of high-grade transient forebrain ischemia. Twenty-six fasted Wistar rats underwent bilateral common carotid artery occlusion and severe hypotension (50 mmHg) for 10 min. The agent (2...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)01952-6
更新日期:1999-10-16 00:00:00
abstract::Ibogaine, a naturally occurring iboga alkaloid, has been claimed to be effective in treating addiction to opioids and stimulants, and has been reported to inhibit morphine and cocaine self-administration in rats. However, ibogaine also has acute nonspecific side effects (e.g. tremors, decreased motivated behavior in g...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00056-x
更新日期:1996-05-06 00:00:00
abstract::The present electric shock (ES) schedule followed in these experiments produced different functional changes in endogenous putative opioid agonist- and antagonist-type receptors, depending on the type of receptor: the amount of antagonist binding was increased by ES application, while the amount of agonist binding was...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91155-2
更新日期:1985-09-16 00:00:00
abstract::Little is known about putative transmitters in the nucleus ambiguus (NA) mediating parasympathetic control of the heart, although Met-enkephalin (m-ENK), Leu-enkephalin (l-ENK), substance P (SP) and acetylcholine (Ach) have been detected in the cell bodies and fibers of this nucleus. The effects of these substances on...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91534-8
更新日期:1991-11-01 00:00:00
abstract::It has been suggested that individual predisposition to develop amphetamine self-administration is associated with impairment in corticosteroid negative feedback mechanisms. Since corticosteroid receptors, particularly those in the hippocampus, are involved in corticosterone feedback sensitivity, we examined the relat...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91137-p
更新日期:1991-05-10 00:00:00
abstract::Adult Wistar rats injected with the dopamine receptor agonist apomorphine display different types of motility patterns with respect to oral stereotypes and locomotor activities. It was tested whether phenotypes exhibiting either 'sniffing' or 'non-sniffing' behaviour differed in gene structures of dopamine receptors D...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)03136-5
更新日期:2002-02-01 00:00:00
abstract::Traumatic brain injury (TBI) contributes to morbidity in children, and more boys experience TBI. Cerebral autoregulation is impaired after TBI, contributing to poor outcome. Cerebral Perfusion Pressure (CPP) is often normalized by use of vasoactive agents to increase mean arterial pressure (MAP). In prior studies of n...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2017.06.010
更新日期:2017-09-01 00:00:00
abstract::Whole-cell patch-clamp recordings were used to investigate electrophysiological effects of neurotensin on acutely isolated dopaminergic (DA) neurons of the rat substantia nigra pars compacta (SNC). During current-clamp recordings, neurotensin depolarized DA neurons and triggered action potentials. Under voltage-clamp ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00379-5
更新日期:1995-06-19 00:00:00
abstract::Introduction of 15-30 U of interleukin-2 (IL-2) into the 3rd ventricle of Wistar rats was followed by a marked and significant decrease in neuron discharge frequency in the ventromedial nucleus of hypothalamus and a marked increase in the supraoptic and paraventricular nuclei. The monoclonal antibody ART62 partly bloc...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)90578-1
更新日期:1988-10-11 00:00:00
abstract::Combined amylin+leptin (AMN+LEP) can reduce diet induced obesity and is very effective in combating LEP resistance. The purpose of this study was to evaluate the effect of AMN+LEP on central histaminergic signaling in lean and obese rats. Male rats were administered LEP (300 μg/kg/d), AMN (100 μg/kg/d), AMN+LEP or veh...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2011.12.022
更新日期:2012-03-09 00:00:00
abstract::One optic nerve of mature goldfish was crushed in the orbit and allowed to regenerate. During regeneration impulse activity was eliminated by periodic intraocular injections of tetrodotoxin (TTX). At 32-104 days, the retinotopography of the retinotectal projection was measured autoradiographically by intraocular [3H]p...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(83)90068-8
更新日期:1983-02-01 00:00:00
abstract::Previous studies showed that electroacupuncture (EA) significantly attenuates inflammatory hyperalgesia in a complete Freund's adjuvant (CFA)-induced inflammatory pain rat model. The present study demonstrates that pretreatment with Derm-sap, a selective toxin for neurons that contain mu opioid receptor (MOR), specifi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.05.008
更新日期:2005-06-28 00:00:00
abstract::Current and voltage clamp recordings were made with a patch-clamp technique from large, light, dorsal root ganglia (DRG) neurons in tissue culture, derived from trisomy 16 and normal fetal mice. In a Na gradient of [52 mM]o/[28 mM]i, the action potential was accelerated, depolarization and repolarization were faster a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(88)90052-1
更新日期:1988-02-01 00:00:00
abstract::Previous studies have demonstrated that punctate injections of 6-hydroxydopamine (6-OHDA) into structures along the ventral lamina terminalis reduce drinking responses elicited by angiotensin II (ANG II). The purpose of the present study was to extend these findings by quantifying the catecholamine depletions that are...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)91567-9
更新日期:1989-02-20 00:00:00
abstract::Morphologically distinct subsets of mesotelencephalic neurons were sought following retrograde transport of Fluoro-Gold from iontophoretic injections relatively restricted to the medial shell, core or rostral pole subterritories of the nucleus accumbens. The diameter and lengths of Fluoro-Gold immunolabeled dendrites ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00556-6
更新日期:1995-08-14 00:00:00
abstract::Immunofluorescence on primary dissociated rat neuronal cultures (cortical, hippocampal, and cerebellar) and organotypic hippocampal cultures was used to investigate the pattern of distribution of cell-surface amyloid protein (APP). Antibodies directed against the extracellular (N-terminal) portion of APP or against th...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00608-7
更新日期:1996-10-07 00:00:00
abstract::The median preoptic nucleus (MnPN) of the hypothalamus contains sleep-active neurons including sleep-active GABAergic neurons and is involved in the regulation of nonREM/REM sleep. The hypocretinergic (HCRT) neurons of the perifornical-lateral hypothalamic area (PF-LHA) and serotonergic (5-HT) neurons of the dorsal ra...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2008.07.115
更新日期:2008-10-09 00:00:00
abstract::The spinal cord dorsal horn contains neural mechanisms which can greatly facilitate pain. We have recently shown that 'illness'-inducing agents, such as intraperitoneally administered lipopolysaccharide (LPS; bacterial endotoxin), can produce prolonged hyperalgesia. This hyperalgesic state is mediated at the level of ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91948-8
更新日期:1994-11-21 00:00:00
abstract::About 45% of the serotonergic raphe neurons are reported to express nerve growth factor (NGF) receptors. We therefore investigated whether selective serotonergic lesions of the median or dorsal raphe nuclei are associated with changes in NGF protein levels of the brain and whether the loss of serotonergic function alt...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)02611-7
更新日期:2001-07-13 00:00:00
abstract::Angiotensin peptides are thought to act as neurotransmitters or neuromodulators in central osmoregulation. We tested the hypothesis that angiotensin peptides are released in the paraventricular nucleus (PVN) of the hypothalamus upon local osmotic stimulation. Brain microdialysis and radioimmunoassay (RIA) techniques w...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91215-7
更新日期:1994-02-21 00:00:00
abstract::Amphetamine releases dopamine through a transporter-mediated mechanism. The purpose of this report was to further our understanding of the intracellular pool from which amphetamine releases dopamine: the cytoplasmic pool, the vesicular pool, or both. Rats were treated with D-amphetamine (AMPH) (1.0 or 10.0 mg/kg) or a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00720-3
更新日期:1998-09-21 00:00:00
abstract::Anandamide (arachydonylethanolamide) is a naturally-occurring ligand of the canabinoid receptor. When anandamide binds to its receptor, adenylate cyclase is inhibited. At the frog neuromuscular junction, anandamide lessened the increase in quantal size produced by pretreatment in hypertonic solution. It did not alter ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91062-6
更新日期:1994-06-27 00:00:00
abstract::Gamma-hydroxybutyrate (GHB) at low doses (5-10 mg/kg i.p.) increased and at high doses (160-320 mg/kg i.p.) decreased the spontaneous firing rate of prefrontal cortex (PFC) neurons recorded in urethane-anesthetized rats. Only excitations were blocked by NCS-382, a specific GHB receptor antagonist; this suggests that t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)01461-p
更新日期:1995-02-27 00:00:00
abstract::Early environmental factors can modulate the development of the hypothalamic-pituitary-adrenal (HPA) axis response to stress, together with subsequent brain functions and emotional behaviors. Two rat strains, Sprague-Dawley (SD) and Fischer 344 (F344), are known to exhibit differences in HPA axis reactivity and anxiet...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2009.11.070
更新日期:2010-02-26 00:00:00