Abstract：
:This study investigated the effects of morphine microinjection into the nucleus raphe magnus (RMg) on electrically evoked C-fiber activities of convergent neurons in the spinal trigeminal nucleus oralis (Sp5O), in halothane-anesthetized rats. Although the neurons could be depressed by systemic morphine (6 mg/kg, i.v.) in a naloxone-reversible fashion, morphine microinjected into the RMg (2. 5 microgram or 5 microgram) neither depressed their C-fiber-evoked responses, nor the diffuse noxious inhibitory controls acting on them. It is concluded that the RMg is not involved in reinforcing descending inhibitory controls that are tonic or triggered by noxious stimuli acting on Sp5O convergent neurons.
journal_name
Brain Resjournal_title
Brain researchauthors
Dualé C,Molat JL,Dallel Rdoi
10.1016/s0006-8993(98)00659-3subject
Has Abstractpub_date
1998-08-24 00:00:00pages
208-11issue
1-2eissn
0006-8993issn
1872-6240pii
S0006-8993(98)00659-3journal_volume
803pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Despite insights into an increasingly significant role for delta opioid receptors in thermoregulation, it is unclear whether delta receptors located in the brain or periphery play the more critical role in body temperature regulation. Moreover, it is not entirely clear which delta receptor phenotype, delta1 or delta2,...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.04.074
更新日期：2005-07-05 00:00:00
abstract：:We electrically stimulated individual Mauthner (M-) cells to determine their motor contribution to C-starts of swimming goldfish. In comparison with sensory-evoked C-starts, M-reflexes triggered by electrical stimulation of single M-cells were significantly weaker and less variable. Stage 1 turns were both longer in d...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91012-6
更新日期：1990-05-28 00:00:00
abstract：:Diffusion patterns of 14C-labeled penicillin, resulting from microinjections into different neocortical laminae, were compared with simultaneous electrophysiologic monitoring of epileptogenesis across these laminae. Injections into layer IV produced response alterations quickly in all recorded layers even with penicil...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90957-0
更新日期：1984-01-09 00:00:00
abstract：:Excitatory amino acid neurotoxicity and the inflammatory response are suspected as mediators of some of the pathological sequelae occurring as a result of spinal cord injury. Here we report temporal and regional increases of the NMDA receptor agonist, quinolinic acid (QUIN), in an experimental model of spinal contusio...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)91560-1
更新日期：1994-01-07 00:00:00
abstract：:Secretion and progressive cerebral accumulation of beta-amyloid peptides (Abeta) derived by endoproteolytic ("amyloidogenic") processing of beta-amyloid precursor protein (APP) represent collectively an early and necessary event in the pathogenesis of Alzheimer's disease. We previously demonstrated that secretion of t...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.01.031
更新日期：2008-03-10 00:00:00
abstract：:The effects of intracerebral injections of brain-gut peptides in the preoptic region on the secretion of luteinizing hormone (LH) and prolactin (PRL) were examined in ovariectomized, estrogen-primed rats. Gastrin or cholecystokinin-octapeptide injection in the preoptic region induced a moderate increase of circadian r...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90330-1
更新日期：1987-05-05 00:00:00
abstract：:The influence of the superficial layers of the superior colliculus (SC) on responses of the lateral geniculate nucleus was studied in anesthetized and paralyzed rabbits. Fifty to one hundred nanoliters of inactivating drugs were injected through a micropipette positioned in the SC in register with the geniculate cells...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90959-5
更新日期：1986-06-04 00:00:00
abstract：:Alterations in the membraneous organelles were studied in two experimental neuropathies: 2,5-hexanedione (2,5-HD) and beta,beta'-iminodiproprionitrile (IDPN), both of which exhibit massive neurofilamentous accumulation. The membranous organelles were stained using the diaminobenzidine potassium ferrocyanide (DPF) meth...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90489-4
更新日期：1983-06-06 00:00:00
abstract：:The firing patterns of up to 4 concurrently active masseter motor units were studied with intramuscular electrodes during a continuous isometric contraction of 15 min duration, in which the subject maintained the mean firing rate of one selected unit at 10 Hz. With this paradigm the net excitation (i.e. mean firing ra...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90467-a
更新日期：1991-05-24 00:00:00
abstract：:Previous findings from this laboratory demonstrating changes in dopamine (DA) transporter and D2 receptors in the amygdaloid complex of subjects with major depression indicate that disruption of dopamine neurotransmission to the amygdala may contribute to behavioral symptoms associated with depression. Quantitative re...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.02.009
更新日期：2008-05-01 00:00:00
abstract：:Brain-derived angiotensin II (ANG II) and prostaglandins have important roles in the regulation of body fluid and blood pressure homeostasis. In the present studies we investigated the central interactions between these two neurochemical products in regulating the hypothalamo-neurohypophysial system during dehydration...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)03113-9
更新日期：2001-01-19 00:00:00
abstract：:We have examined the effects of isotonic hypovolemia on the expression of the neuronal nitric oxide synthase (nNOS) gene in the paraventricular (PVN) and supraoptic nuclei (SON) of the rat, using in situ hybridization histochemistry with a 35S-labelled oligodeoxynucleotide probe complementary to nNOS mRNA. Intraperito...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)01531-x
更新日期：1998-04-20 00:00:00
abstract：:Onset of hearing in the ferret was judged by simple behavioral, physiological and anatomical indices. The ear canals do not open until the end of the first postnatal month. This coincides with the appearance of a startle response to loud hand claps and the recording of acoustically activated neurons in the midbrain. T...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90698-9
更新日期：1982-12-16 00:00:00
abstract：UNLABELLED:The effects of acute and chronic exposure to phencyclidine (PCP) on the regulation of prolactin (PRL) secretion were examined. Female Sprague-Dawley rats were injected with PCP (10 mg/kg) or saline for 14 days, or just prior to the administration of the serotonin precursor, 5-hydroxytryptophan (5-HTP). A sin...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90764-z
更新日期：1992-02-28 00:00:00
abstract：:Nestin is an embryonic intermediate filament that transiently expressed in the neural stem/progenitor cells in the developing central nervous system (CNS). Growing evidence has shown that abundant expression of nestin also occurs in both pathological glial-derived tumor cells and reactive astrocytes in various CNS inj...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.11.026
更新日期：2008-02-27 00:00:00
abstract：:Maternal care is crucial for offspring development and licking/grooming patterns can be induced by sensorial, neuroendocrine, and metabolic variations in the CNS. Important brain functions, such as learning and memory, can be influenced by oxidative stress, which can also modulate pathophysiological processes (e.g., d...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2016.11.010
更新日期：2017-01-15 00:00:00
abstract：:Corticotropin-releasing factor (CRF) has been hypothesized to be involved in the pathophysiology of anxiety, depression, cognitive and feeding disorders. Two distinct CRF receptor subtypes, CRFR1 and CRFR2, are thought to mediate CRF actions in the CNS. However, the role for each receptor subtype in animal models of n...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)01158-5
更新日期：1999-07-17 00:00:00
abstract：:The purpose of this study was to investigate morphological characteristics of the synaptic relations of choline acetyltransferase (ChAT)-positive terminals that are made with a variety of post-synaptic profiles in the lateralis medialis-suprageniculate nuclear complex (LM-Sg) using ChAT, gamma-aminobutyric acid (GABA)...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(96)01208-5
更新日期：1997-01-30 00:00:00
abstract：:Astrogliogenesis in the human fetal cerebellum was examined in 46 cerebella obtained from hysterotomy specimens ranging between 9 and 20 weeks of ovulation age. By correlating the results obtained by rapid Golgi and Golgi-Cox methods, the indirect immunofluorescence technique for glial fibrillary acidic protein, and e...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)90280-2
更新日期：1980-05-26 00:00:00
abstract：:Cultured astrocytes contain immunologically specific aromatic L-amino acid decarboxylase (AADC) protein and express the AADC gene. Following incubation with L-Dopa, glial cultures synthesize and metabolize dopamine. The addition of pyridoxal 5-phosphate did not change the rate of dopamine synthesis. The formation of d...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90592-b
更新日期：1993-10-29 00:00:00
abstract：:Two high molecular weight surface glycoproteins of cerebellar cells which are selectively labeled by lactoperoxidase-catalyzed iodination of monolayer cultures from the developing mouse cerebellum, have been identified and partially characterised. Both molecules, called peak 2 and peak 3 proteins, were the major glyco...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)91197-x
更新日期：1980-01-27 00:00:00
abstract：:Activation of serotonin neurotransmission produces increase of plasma oxytocin, prolactin, vasopressin and ACTH levels. Using dual-immunocytochemistry, the number of oxytocinergic neurons in the hypothalamic magnocellular nuclei co-storing Fos after administration of D-fenfluramine was found to be 15-fold higher compa...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01953-8
更新日期：1999-12-18 00:00:00
abstract：:There is evidence that heme oxygenase plays a role in cellular defense against reactive oxygen species and thereby has neuroprotective effects. We examined the interaction of Neotrofin, a cognitive-enhancing and neuroprotective drug, with the heme oxygenase system. In adult rats, both a single administration or seven ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03670-3
更新日期：2003-02-07 00:00:00
abstract：:The present study examined the effect of chronic paroxetine (10 mg/kg p.o., 21 days) on the 5-HT1B and 5-HT1D autoreceptors controlling 5-HT efflux in slices of rat ventrolateral geniculate nucleus. Electrically stimulated 5-HT efflux (10 pulses, 200 Hz, 0.1 ms, 10 mA) was measured using fast cyclic voltammetry. Peak ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00289-8
更新日期：1997-06-20 00:00:00
abstract：:This freeze-fracture study examines the development of myelinated fibers in the rat optic nerve. Axolemma of optic nerve fibers were studied before, during, and after myelination. At birth, the optic nerve is composed entirely of non-myelinated (premyelinated) axons, while in the adult, virtually all fibers acquire co...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90948-9
更新日期：1982-10-28 00:00:00
abstract：:Wild red foxes, proverbially cunning carnivores, are investigated for adult hippocampal neurogenesis and morphological characteristics of the dentate gyrus. Adult red foxes harbor almost 15-times more young, doublecortin-positive neurons in their dentate gyrus than domesticated dogs. The number of doublecortin-positiv...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.02.075
更新日期：2010-04-30 00:00:00
abstract：:The subfornical organ of the brain has a role in the regulation of fluid balance in higher animals. In this study the effects of salt loading and water deprivation on specific proteins in this organ were investigated. For 4 days, 3 groups of rats were given an appropriate fluid diet (control, 2% NaCl and water deprive...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91463-0
更新日期：1986-04-30 00:00:00
abstract：:A search for vasomotor depressor sites in the lateral medullary brainstem of anesthetized cat using microinjections of AMPA has delineated a longitudinal column of sympathoinhibitory neurons consisting of the rostral depressor area, the caudal ventrolateral medulla, and a new intermediate depressor area. Systematic bl...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91257-s
更新日期：1993-02-19 00:00:00
abstract：:The trisomy-16 mouse is considered to be a model of human trisomy-21 (Down syndrome). We have examined the electrical membrane properties of cultured dorsal root ganglion (DRG) neurons from normal and trisomy-16 fetuses. Trisomy-16 neurons had significantly accelerated rates of action potential depolarization and repo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90678-1
更新日期：1989-04-17 00:00:00
abstract：:The research question was, do events arising from rhythmic passive movement of the human leg lead to inhibition of the H reflex pathway in the stationary leg contralateral to that movement? Further, as the angular velocity of the passive movement increases, does the contralateral reflex inhibition also increase? Stabl...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91303-a
更新日期：1993-02-12 00:00:00
