Abstract：
:The influence of the superficial layers of the superior colliculus (SC) on responses of the lateral geniculate nucleus was studied in anesthetized and paralyzed rabbits. Fifty to one hundred nanoliters of inactivating drugs were injected through a micropipette positioned in the SC in register with the geniculate cells. The latter were tested with discrete moving and stationary targets presented in random sequences. Results revealed that the SC exerted a dual facilitative (n = 19) and inhibitory (n = 25) influence. The latter segment of the response pattern was modified while the initial portion remained unchanged. In some cases differential effects were observed, that is, the responses to one particular stimulus were more affected than responses to other modalities. However, in the majority of cells it was the on-off responses which were most affected. These findings point toward complex influences of the SC upon geniculate responses in rabbits. This complexity is also supported by findings that in cats the colliculo-geniculate synapses are of various types.
journal_name
Brain Resjournal_title
Brain researchauthors
Molotchnikoff S,Delaunais D,Casanova C,Lachapelle Pdoi
10.1016/0006-8993(86)90959-5subject
Has Abstractpub_date
1986-06-04 00:00:00pages
66-72issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(86)90959-5journal_volume
375pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Endoplasmic reticulum (ER) and mitochondria dysfunction contribute to insulin resistance generation during obesity and diabetes. ER and mitochondria interact through Mitofusin 2 (MTF2), which anchors in the outer mitochondrial and ER membranes regulating energy metabolism. Ablation of MTF2 leads to ER stress activatio...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.09.014
更新日期：2015-11-19 00:00:00
abstract：:Rats with 6-hydroxydopamine (6-OHDA) lesions of the nigrostriatal pathway show enhanced locomotor and stereotyped behaviors when challenged with direct and indirect dopamine (DA) agonists due to the development of postsynaptic supersensitivity. To determine if this phenomenon generalizes to other motor behaviors, we h...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02753-0
更新日期：2000-10-06 00:00:00
abstract：BACKGROUND:It is unclear whether spinal cord stimulation (SCS) at higher frequencies induces further increases in vasodilation and enhances clinical efficacy. OBJECTIVES:This study investigated effects of SCS at both a normal frequency (as used clinically) and two higher frequencies on peripheral vasodilation. METHOD...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.11.072
更新日期：2010-02-08 00:00:00
abstract：:To determine whether the cytokine, interleukin-1 beta, is present in the rat brain as has been reported in human brain, immunocytochemical studies were performed using an antiserum that recognizes recombinant, rat IL-1 beta. Immunoreaction product was present in the periventricular and medial hypothalamus, mossy fiber...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90445-h
更新日期：1990-04-23 00:00:00
abstract：:Oxytocin properties have been studied in different experimental models in order to obtain evidence for its analgesic properties. The analgesic effect of an oxytocinergic pathway descending from the hypothalamus reaching the dorsal horn of the spinal cord has been studied. In anesthetized rats, we recorded single units...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.01.050
更新日期：2006-04-07 00:00:00
abstract：:The postnatal maturation of the medial preoptic area (MPOA) of male and female rats was studied by means of light and electron microscopy. In Golgi-Kopsch preparations, bi- and multipolar cells were present at birth in both sexes; the perikarya of most of these cells, as seen with the electron microscope, exhibited an...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(77)90454-1
更新日期：1977-02-25 00:00:00
abstract：:A sizeable, feedforward, GABAergic projection exists from the inferior colliculus to the medial geniculate body in cats. We compared the dimensions of GABA-immunoreactive and non-immunoreactive axons in the brachium of the cat inferior colliculus, and demonstrate that GABA-immunoreactive axons are among the largest of...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00654-9
更新日期：1997-08-08 00:00:00
abstract：:The neuropathological consequences of acute exposure to the neurotoxicants ammonia and octanoic acid were investigated with the isolated, perfused canine brain preparation. After 1 h of combined hyperammonemia and octanoic acidemia, ultrastructural changes were apparent in all brain regions examined. The cell bodies o...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90916-3
更新日期：1985-08-12 00:00:00
abstract：:The metabolic effects of intravenous administration of 200 mg/kg imidazole-4-acetic acid (IMA) on normoxic, hypoxemic and hypoxemic-oligemic rat brain were assessed by measurement of the cerebral contents of energy phosphates and selected glycolytic-citric acid cycle intermediates. In normoxic brain IMA was associated...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90286-4
更新日期：1982-01-28 00:00:00
abstract：:Three hours after administration of the pro-oxidant 2-cyclohexen-1-one, calpain activity was significantly reduced in the brain of young rats, but not in the brain of adult rats, and cathepsin D activity remained unchanged. Addition of isovalerylcarnitine to the incubation medium increased calpain activity 5-7-fold, c...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91560-2
更新日期：1992-11-20 00:00:00
abstract：:Seventy-two hybridoma lines that produce monoclonal antibodies to molecules of a rat synaptosomal plasma membrane fraction (SPM) were generated. The topographical distribution of the antigens in the cerebellum and other areas of the brain was studied by light microscopy immunocytochemistry. Some of the antibodies reco...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90118-5
更新日期：1984-11-26 00:00:00
abstract：:Defeat stress in mice, a model of social stress, increases benzodiazepine receptor binding as measured by specific [3H]Ro15-1788 binding in vivo, but not by [3H]flunitrazepam binding in vitro. This increase occurs rapidly, by 20 min following exposure to stress, and resolves by 60 min. Increased benzodiazepine recepto...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90023-0
更新日期：1987-06-30 00:00:00
abstract：:When rabbit retinas are exposed in vitro to specific excitatory amino acid receptor agonists certain GABAergic amacrine cells are activated to cause a release of GABA. The GABA that is not released can be detected by immunohistochemistry. Exposure of tissues to kainate or NMDA each caused a characteristic change in th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)91510-5
更新日期：1994-12-26 00:00:00
abstract：:It is well established that autonomic control of digestive function is modulated by central autonomic neurotransmission. In this context it has been shown that digestive function can be modulated by exogenous neuropeptides microinjected into specific brain sides. Furthermore, there is considerable evidence suggesting ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.12.034
更新日期：2005-03-02 00:00:00
abstract：:After transplantation of autologous sciatic nerve segments into the retina of adult hamsters for 1-2 months, retrograde labelling with horseradish peroxidase demonstrated a population of ganglion cells situated peripheral to the graft. If an additional lesion was placed between the insertion of the graft and the optic...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91203-5
更新日期：1986-07-02 00:00:00
abstract：:Neurons located in the nucleus raphe magnus (NRM), a region important in the control of nociception, appear to be tonically inhibited by noradrenergic (NA) neurons. Anatomical studies have suggested that the A5 catecholamine nucleus may be the primary source of noradrenergic neurons whose terminals are located in the ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91108-x
更新日期：1986-04-02 00:00:00
abstract：:Our previous work has demonstrated that 100-Hz electroacupuncture (EA) or 100-Hz transcutaneous electrical nerve stimulation (TENS) was very effective in ameliorating the morphine withdrawal syndrome in rats and humans. The mechanism was obscure. (1) Rats were made dependent on morphine by repeated morphine injections...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)02069-7
更新日期：1999-12-18 00:00:00
abstract：:The dorsolateral quadrant of the lateral septal nucleus receives projections from both the ipsilateral and the contralateral fimbria. In the adult rat the effect of fimbrial lesions on synapse formation has been studied by a quantitative electron microscopic analysis of the various types of synapses present, using ele...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)90010-4
更新日期：1980-05-05 00:00:00
abstract：:William James noted that memories could persist from minutes to weeks. This essay attempts to explain this variation by situating the explanation in the biochemistry of dendritic spines. Two outcomes are critical to generate the synaptic basis of memory: (1) the actin cytoskeleton in the spine must be degraded to perm...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2014.12.009
更新日期：2015-09-24 00:00:00
abstract：:Myelination is an important process in brain development, and delays or abnormalities in this process have been associated with a number of conditions including autism, developmental delay, attention deficit disorder, and schizophrenia. Myelination can be sensitive to developmental experience; however, although the ad...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.06.087
更新日期：2009-09-08 00:00:00
abstract：:Chick embryos ranging in age from 4.0 to 18 days of incubation and 1-2-day-old hatchlings received injections of HRP solutions directly into the leg musculature. After survival periods of from 5 to 25 h motoneurons and cells in the spinal sensory ganglia were found to be stained with the HRP reaction product. It was f...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(75)90007-4
更新日期：1975-11-14 00:00:00
abstract：:Glycine is taken up twice as rapidly by neurons R3-R14 as by other identified neurons in the Aplysia parietovisceral ganglion. Earlier studies had shown that R3-R14 have much higher glycine concentrations than other Aplysia neurons. Most of the glycine taken up by R3-R14 was biochemically untransformed for at least 1 ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(78)91049-1
更新日期：1978-10-06 00:00:00
abstract：:Intracellular recordings in vivo from serotonergic dorsal raphe neurons of the rat brain reveal that these cells undergo a pronounced postspike hyperpolarization followed by a gradual interspike depolarization leading to the succeeding spike. Such repetitive cycles of interspike hyperpolarization and depolarization, w...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90124-x
更新日期：1982-04-29 00:00:00
abstract：:Rabbit retina was used as a model to study the possible role of taurine in the retina. The taurine-synthesizing enzyme, cysteine sulfinic acid decarboxylase (CSAD), is localized immunohistochemically using specific antibodies against CSAD. The CSAD-immunoreactivity appears to be most prominent in the inner nuclear lay...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90066-6
更新日期：1985-07-01 00:00:00
abstract：:Alterations in neurotrophic signaling pathways may contribute to the changes in the mesolimbic dopamine system induced by chronic morphine exposure. In a rat model of morphine dependence, we previously identified increased levels of phospholipase C gamma-1 (PLCgamma1) immunoreactivity specifically within the ventral t...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.04.059
更新日期：2007-07-02 00:00:00
abstract：OBJECTIVE:The purpose of this study is to characterize functional connectivity changes in mild cognitive impaired Alzheimer's disease (MCI-AD) under resting and cognitive task conditions. METHOD:EEG signals were recorded under resting states (Eyes closed (EC) and Eyes open (EO)) and cognitive states (Mental Arithmetic...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2020.146743
更新日期：2020-05-15 00:00:00
abstract：:The neurotoxic effects of exogenous glutamate were studied in the rat cochlea. Glutamate-treated rats (4 g/kg/day i.p., postnatal days 2-9) exhibited electrophysiologically-measured elevations in high frequency thresholds usually associated with hair cell loss in the basal region of the cochlea. While surface preparat...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90090-i
更新日期：1991-06-28 00:00:00
abstract：:This study shows that the axons of some raphespinal sympathoinhibitory neurons projecting to the third thoracic spinal segment emit branches in the third-fourth cervical spinal segments of cats. This was demonstrated by using time-controlled collision of neuronal action potentials initiated by stimuli applied at these...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)91417-5
更新日期：1988-02-16 00:00:00
abstract：:Humans share the common intuition of a self that has access to an inner 'theater of mind' (Baars, 2003). The problem is how this internal theater is formed. Moving from Cook's view (Cook, 2008), we propose that the 'sentience' present in single excitable cells is integrated into units of neurons and glial cells transi...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2012.01.003
更新日期：2012-10-02 00:00:00
abstract：:The intracellular pH, 7.54 +/- 0.03 (mean +/- S.D., n = 15), determined with the Neutral red method, of the hippocampal brain slice preparation under baseline incubation conditions is considerably more alkaline than the bath buffer pH. Neutralization by amiloride suggests that the alkalinity was due to Na+/H+ exchange...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00512-4
更新日期：1996-08-26 00:00:00
