Abstract：
:Bilateral intraventricular injections of 6-hydroxydopamine depleted dopamine (DA) in striatal tissue of rats by 88%. Tail shock increased DA in striatal extracellular fluid of these rats from 10 to 17 pg/20 microliters as measured by microdialysis, values less than half those seen in normal striatum. The increase was observed even in rats that were akinetic. DA in extracellular fluid after stress was negatively correlated with behavioral performance. Thus, residual nigrostriatal DA neurons are responsive to stress but do not produce normal DA levels in striatal extracellular fluid.
journal_name
Brain Resjournal_title
Brain researchauthors
Keefe KA,Stricker EM,Zigmond MJ,Abercrombie EDdoi
10.1016/0006-8993(90)91158-dsubject
Has Abstractpub_date
1990-09-17 00:00:00pages
350-3issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(90)91158-Djournal_volume
527pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Dexmedetomidine (Dex) has the neuroprotective effect on cerebral ischemia-reperfusion injury (CIRI). But the mechanism is not yet clear. In this study, we established a model of middle cerebral artery occlusion (MCAO) and treated primary cortical neurons with oxygen glucose deprivation (OGD), followed by Dex treatment...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2018.09.007
更新日期：2018-12-15 00:00:00
abstract：:Extracellular microelectrode recordings were made from a total of 868 neurons in the medullas of cats in regions known to contain high densities of respiratory-related neurons (solitary tract complex, nucleus ambiguus/retroambigualis, lateral tegmental field). Both the discharge patterns and the locations of units wer...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90979-x
更新日期：1984-03-19 00:00:00
abstract：:We have previously shown that systemic administration of ondansetron, a selective serotonin type-3 (5-HT3) receptor antagonist, attenuates cholecystokinin (CCK)-induced suppression of food intake. The exact location of 5-HT3 receptors mediating this action is not clear and may involve hindbrain 5-HT3 receptors. In thi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.05.058
更新日期：2006-08-04 00:00:00
abstract：:In the inferior colliculus of the mouse, 4 cell types project across the collicular commissure: small to medium sized spiny cells, small to medium sized spineless cells, medium sized sparsely spinous neurons and large cells. The axons of large cells give rise to a great number of ipsi- and contralateral collaterals te...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90571-8
更新日期：1986-03-19 00:00:00
abstract：:The myosin S-1 subfragment was used to label actin filaments in the developing rat brain. The results show actin filaments present throughout the dendritic region with highest concentrations within growth cones and regions of spine development. Between 6 and 25 days postnatal, spines became more complex and actin fila...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(86)90253-1
更新日期：1986-06-01 00:00:00
abstract：:Insulin-like 6 immunoreactivity (irINSL6) was detected in Leydig cells of the mouse testis. In the brain, labeled somata were detected mainly in the caudal hypothalamus and midbrain. Double labeling the brainstem sections revealed that irINSL6 somata were 5-hydroxytryptamine (5-HT) positive. The presence of irINSL6 in...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.01.077
更新日期：2005-04-08 00:00:00
abstract：:The effects of recombinant mouse stem cell factor (rmSCF) on paired-pulse facilitation (PPF) and long-term potentiation (LTP) in the mossy fiber (MF)-CA3 pathway were examined in mouse hippocampal slices by recording field EPSPs. When PPF was measured before and 30 min after tetanic stimulation, the initial PPF positi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)02879-2
更新日期：2002-08-16 00:00:00
abstract：:In order to obtain further insight into the interactions between the purinergic and dopaminergic pathways in the striatum, we studied both metabolisms simultaneously, using a microdialysis technique in 1-methyl-1,4-phenylpyridinium ion (MPP+) unilaterally-denervated conscious rats. In these rats the contralateral side...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90052-8
更新日期：1989-03-27 00:00:00
abstract：:Chronic administration of caffeine (s.c. for a period of 14 days in escalating doses of 10-70 mg/kg) increased the sensitivity of rat cerebral cortical neurons to the inhibitory action of microiontophoretically applied adenosine. The sensitivity of spontaneously firing rat cerebral cortical neurons in caffeine-treated...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91722-s
更新日期：1990-06-18 00:00:00
abstract：:Coupling between lumbar motoneurons in the isolated frog spinal cord was studied by using intracellular recordings and intracellular injections of Lucifer Yellow CH. Physiological studies revealed intra- and intersegmental, short latency electrical interactions between many motoneurons. Injections of Lucifer Yellow in...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90721-7
更新日期：1983-09-12 00:00:00
abstract：:We have previously shown that blockade of neurotransmission mediated by gamma-aminobutyric acid (GABA) in the ventromedial nucleus of the hypothalamus (VMH) by the microinjection of a GABAA receptor antagonist, bicuculline methiodide (BM), exclusively induced running activity in the rat. The purpose of the present stu...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91243-l
更新日期：1993-02-19 00:00:00
abstract：:Nuclear factor kappa B (NFkappaB) is a transcription factor which can be activated by some neurotrophic factors and cytokines, and then translocated into the nucleus. We examined NFkappaB immunoreactivity (IR) in L4 and L5 dorsal root ganglion (DRG) cells of normal rats, and 2 weeks after complete sciatic nerve transe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00380-1
更新日期：1998-06-29 00:00:00
abstract：:Systemic injection of kainic acid (KA) in adult rat elicits a pattern of neuronal pathology which exhibits several features of human temporal lobe epilepsy. KA-induced seizure activity is accompanied by the activation of the calcium-dependent protease calpain in limbic structures. In the present study, we evaluated th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)01360-1
更新日期：1996-07-08 00:00:00
abstract：:During early postnatal development in reeler mutant mice, lectin binding delineates prospective abnormal barrels as they will appear in the adult mutant somatosensory cortex. Glial fibers also may be more condensed within fascicles in developing reeler barrels. These fibers also appear to be misaligned, coursing predo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(87)90112-x
更新日期：1987-04-01 00:00:00
abstract：:In the course of pulse-label studies on the axonal transport of the small, basic, actin-binding proteins--actin depolymerizing factor, cofilin and profilin--in chicken motor neurones, we observed a heavily labelled protein of M(r) 18 kDa and pI 8.2 on fluorographs of two-dimensional polyacrylamide gels. On the basis o...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00766-x
更新日期：1997-10-17 00:00:00
abstract：:Neural transplantation is a promising approach for treating neurodegenerative disease. Neural stem/progenitor cells (NPCs) are self-renewing and multipotent and thus are good candidates for donor cells when they have been clearly defined to differentiate into neurons. As neuronal differentiation follows cell cycle exi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.02.046
更新日期：2006-05-30 00:00:00
abstract：:The action of 5-hydroxytryptamine (5-HT) via the 5-HT1A receptor on dissociated rat dorsal raphe neurons was characterized under the whole-cell mode by using the nystatin-perforated patch-clamp technique. Under voltage-clamp conditions, 5-HT induced an inwardly rectifying K+ current (I5-HT) in a concentration-dependen...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(96)01141-9
更新日期：1997-01-16 00:00:00
abstract：:The organization and representation of conceptual knowledge in the brain remains a controversial issue in terms of both neuropsychological and imaging evidence. We report the results of a functional magnetic resonance study in which the role of the most debated dimensions (domain and feature type) was evaluated throug...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.11.070
更新日期：2008-02-15 00:00:00
abstract：:Chick pineal cells contain a circadian oscillator that derives rhythmic synthesis and secretion of melatonin even in dispersed cell culture. Here, we demonstrate that the mRNA encoding tryptophan hydroxylase (TPH), the first enzyme in the melatonin synthetic pathway, is expressed rhythmically under the control of the ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00743-3
更新日期：1996-10-28 00:00:00
abstract：:The retrorubral field (RRF) contains numerous dopaminergic neurons and projects to the parvicellular reticular formation (RFp) of the medullary and pontomedullary brainstem, where many premotor neurons project to the orofacial motor nuclei. To know how the amygdala affects the RRF-RFp pathway in the rat, we first exam...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.09.118
更新日期：2010-01-08 00:00:00
abstract：:Expression of the immediate-early gene c-fos, a marker of neuronal activation, was employed to localize brainstem neuronal populations functionally related to the expiration reflex (ER). Twelve spontaneously breathing, non-decerebrate, pentobarbital anesthetized cats were used. The level of Fos-like immunoreactivity (...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.09.064
更新日期：2007-12-12 00:00:00
abstract：:To assess the role of calcitonin gene-related peptide (CGRP) within the trigeminal subnucleus caudalis (Vc) on adrenal and autonomic function, microinjections were directed at different laminae of Vc in chloralose-anesthetized cats. Microinjections of CGRP (5 pmol, 100 nl) into laminae I-II increased significantly the...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90713-6
更新日期：1991-08-30 00:00:00
abstract：:Field potentials (FP) recorded from the surface of toad's optic tectum (OT) to electrical stimulation of the contralateral optic nerve (ON) show initial positive deflections P*, followed by negative wave N and positive wave P; the former result from axonal inputs, the latter two resemble excitatory and inhibitory post...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)01260-o
更新日期：1995-01-09 00:00:00
abstract：:Human arachnoid villi were studied ultrastructurally to clarify the mechanism of cerebrospinal fluid absorption. Arachnoid villi of humans showed quite different features from those of animals. The former were not always invested with endothelial linings as previously reported in the latter. Instead, there was a cover...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91220-5
更新日期：1986-10-01 00:00:00
abstract：:In anesthetized cats, medial gastrocnemius motor units (MUs) were electrically stimulated via their ventral-root axons with independent random patterns. Muscle tension and homonymous alpha-motoneuron (alpha-MN) membrane potential fluctuations in response to these stimuli were recorded simultaneously. Cross-correlating...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90763-2
更新日期：1985-09-23 00:00:00
abstract：:Transforming growth factor alpha (TGF alpha) has been immunocytochemically localized in neuronal perikarya throughout the adult rat central nervous system (CNS). In order to determine if any TGF alpha-immunoreactive (TGF alpha-I) cell bodies have long axonal projections, indirect immunofluorescence was used in combina...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)91317-5
更新日期：1987-09-22 00:00:00
abstract：:This study examined the effect of feeding either a bland cornstarch-based diet (BCD) or a highly palatable, high fat diet containing sucrose (HPD) on hypothalamic arcuate nucleus (ARC) gene expression for neuropeptide-Y (NPY). Male Sprague-Dawley rats received either BCD ad libitum, HPD ad libitum, HPD pair-fed to the...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00755-0
更新日期：1998-09-21 00:00:00
abstract：:Evidence from human and animal studies has shown that experiences of early attachment can influence brain development and structure. Adult attachment style develops from early attachment experiences. However, little is known about the relationship between gray matter volume and attachment style. Further, the structura...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2018.06.035
更新日期：2018-11-15 00:00:00
abstract：:Water deprivation caused daily urinary Na output to more than double in normal sheep, but caused no increase in Na excretion in sheep (A3VL-sheep) in which the anterior third ventricle wall had been ablated. Dehydrated A3VL-sheep exhibited a much greater degree of hypernatremia than dehydrated normal sheep, although w...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90326-8
更新日期：1983-03-21 00:00:00
abstract：:The actions of convulsant and sedative barbiturates on responses to gamma-aminobutyric acid (GABA) application and on inhibitory postsynaptic currents were compared using voltage-clamp techniques in cultured rat hippocampal neurons. The convulsant barbiturates, 5-ethyl-5-(3-methylbut-2-enyl) barbituric acid (3M2B), an...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90910-4
更新日期：1990-05-14 00:00:00
